scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M212798200 |
P698 | PubMed publication ID | 12704184 |
P50 | author | Sudha Sharma | Q41653425 |
P2093 | author name string | Teresa M Wilson | |
Joshua A Sommers | |||
Robert M Brosh | |||
Henry C Driscoll | |||
Laura Uzdilla | |||
P2860 | cites work | Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance | Q22009967 |
Functional and physical interaction between WRN helicase and human replication protein A | Q22010009 | ||
The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities | Q22010967 | ||
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity | Q22254162 | ||
The interaction of DNA mismatch repair proteins with human exonuclease I | Q24291370 | ||
p53 Modulates the exonuclease activity of Werner syndrome protein | Q24291371 | ||
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity | Q24291787 | ||
Human exonuclease I is required for 5' and 3' mismatch repair | Q24292224 | ||
The Werner syndrome protein is a DNA helicase | Q24310486 | ||
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2 | Q24314329 | ||
Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases | Q24317166 | ||
Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1 | Q24319085 | ||
Mutator phenotype of Werner syndrome is characterized by extensive deletions | Q24609670 | ||
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei | Q27860728 | ||
Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae | Q27934255 | ||
Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate | Q27935216 | ||
Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae | Q28140402 | ||
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity | Q28589633 | ||
Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1 | Q28645598 | ||
Positional cloning of the Werner's syndrome gene | Q29618393 | ||
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes | Q30704734 | ||
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest | Q30983796 | ||
Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines | Q33189110 | ||
Loss of Werner syndrome protein function promotes aberrant mitotic recombination | Q33943676 | ||
Homologous recombination resolution defect in werner syndrome | Q34150355 | ||
Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism | Q34283406 | ||
Roles of the Werner syndrome protein in pathways required for maintenance of genome stability | Q34519481 | ||
Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO. | Q34707698 | ||
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro | Q36568265 | ||
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The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease | Q37083237 | ||
DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system | Q39720740 | ||
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants | Q39860143 | ||
Werner's syndrome cell lines are hypersensitive to camptothecin-induced chromosomal damage | Q40840880 | ||
Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase | Q40968297 | ||
An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants | Q41076163 | ||
The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair | Q41396267 | ||
Homologous recombination is elevated in some Werner-like syndromes but not during normal in vitro or in vivo senescence of mammalian cells | Q41723911 | ||
Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide. | Q53775920 | ||
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells | Q57250868 | ||
SGS1 is required for telomere elongation in the absence of telomerase | Q61782242 | ||
Altered frequency of initiation sites of DNA replication in Werner's syndrome cells | Q70427873 | ||
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts | Q73311217 | ||
Molecular biology. DNA ends ReQ-uire attention | Q73760824 | ||
Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease | Q77677868 | ||
Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase | Q77948758 | ||
Growth characteristics of Werner syndrome cells in vitro | Q93667534 | ||
Autoradiographic studies of DNA replication in Werner's syndrome cells | Q93667542 | ||
P433 | issue | 26 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Werner syndrome | Q1154619 |
P304 | page(s) | 23487-23496 | |
P577 | publication date | 2003-04-18 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein | |
P478 | volume | 278 |
Q36100873 | 14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif |
Q36457060 | ATR-dependent pathways control hEXO1 stability in response to stalled forks. |
Q33327349 | Acetylation regulates WRN catalytic activities and affects base excision DNA repair |
Q33726437 | Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks |
Q24302011 | Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA |
Q34541040 | Chromosome integrity at a double-strand break requires exonuclease 1 and MRX |
Q35961508 | DNA helicases involved in DNA repair and their roles in cancer |
Q33945750 | Delineation of WRN helicase function with EXO1 in the replicational stress response |
Q33529100 | Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA |
Q33684409 | Distinct roles of RECQ1 in the maintenance of genomic stability |
Q38919536 | Exonuclease 1 and its versatile roles in DNA repair |
Q35869772 | Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics |
Q55242530 | Genetic mutants illuminate the roles of RecQ helicases in recombinational repair or response to replicational stress. |
Q37308985 | Hitting the bull's eye: novel directed cancer therapy through helicase-targeted synthetic lethality |
Q60934518 | Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer |
Q36185175 | Human exonuclease 1 (EXO1) activity characterization and its function on flap structures |
Q28299185 | Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair |
Q36573932 | Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability |
Q35153516 | Mechanistic analysis of Xenopus EXO1's function in 5'-strand resection at DNA double-strand breaks |
Q38050774 | Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems |
Q37790458 | Nucleases: diversity of structure, function and mechanism. |
Q24810298 | Phosphorylation of human oxoguanine DNA glycosylase (alpha-OGG1) modulates its function |
Q38201043 | Probing Genome Maintenance Functions of human RECQ1. |
Q36101151 | Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples. |
Q24301788 | RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination |
Q35638929 | RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin. |
Q36204365 | Regulation of chromatin structure by poly(ADP-ribosyl)ation |
Q33317311 | Rice exonuclease-1 homologue, OsEXO1, that interacts with DNA polymerase lambda and RPA subunit proteins, is involved in cell proliferation |
Q34812299 | Roles of the Werner syndrome RecQ helicase in DNA replication |
Q24302463 | Stimulation of flap endonuclease-1 by the Bloom's syndrome protein |
Q27667527 | Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family |
Q37161449 | Telomeres do the (un)twist: helicase actions at chromosome termini |
Q37064133 | The BLM dissolvasome in DNA replication and repair. |
Q24671253 | The hSNM1 protein is a DNA 5'-exonuclease |
Q36483126 | The role of DNA exonucleases in protecting genome stability and their impact on ageing. |
Q36740600 | Unique and important consequences of RECQ1 deficiency in mammalian cells |
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