The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions

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The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions is …
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scholarly articleQ13442814

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P819ADS bibcode1988PNAS...85.2709N
P356DOI10.1073/PNAS.85.8.2709
P932PMC publication ID280068
P698PubMed publication ID3128795

P2093author name stringJ H Miller
M Cabrera
Y Nghiem
C G Cupples
P2860cites workMutagenesis by apurinic/apyrimidinic sitesQ28300337
Linkage map of Escherichia coli K-12, edition 7Q33627756
Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replicationQ34257072
Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induce base substitutions via specific transversionsQ34277036
Analysis of spontaneous base substitutions generated in mismatch-repair-deficient strains of Escherichia coliQ36259051
Spontaneous mutators of salmonella typhimurium LT2 generated by insertion of transposable elementsQ36307872
Isolation of an Escherichia coli K-12 dnaE mutation as a mutatorQ36418700
Escherichia coli K-12 mutants deficient in uracil-DNA glycosylaseQ36421752
The unusual mutagenic specificity of an E. Coli mutator geneQ36456280
Base substitution mutations induced by metabolically activated aflatoxin B1.Q37610673
Spontaneous mutagenesis in Escherichia coli strains lacking 6-methyladenine residues in their DNA an altered mutational spectrum in dam− mutantsQ41021768
Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coliQ41379292
Genetic studies of the lac repressor. III. Additional correlation of mutational sites with specific amino acid residuesQ42028460
Bacterial mutator genes and the control of spontaneous mutationQ50228161
Mutational specificity of a conditional Escherichia coli mutator, mutD5Q54154876
Base pairing and fidelity in codon-anticodon interactionQ59056701
Mutagenic deamination of cytosine residues in DNAQ59062016
Mutator gene studies in Escherichia coli: the mutT geneQ69269829
The specificity of base-pair substitution induced by the mutL and mutS mutators in E. coliQ69884370
Mutagenic specificity of ultraviolet lightQ69946985
Specificity of mutagenesis resulting from the induction of the SOS system in the absence of mutagenic treatmentQ70352825
Repair of DNA base-pair mismatches in extracts of Escherichia coliQ70415906
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)2709-2713
P577publication date1988-04-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions
P478volume85

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cites work (P2860)
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Q54522117Familial adenomatous polyposis and MYH.
Q44643713Fission yeast Uve1 and Apn2 function in distinct oxidative damage repair pathways in vivo
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Q42166009Mismatch Repair Modulation of MutY Activity Drives Bacillus subtilis Stationary-Phase Mutagenesis
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Q43939673Molecular dynamics simulation of 7, 8-dihydro-8-oxoguanine DNA.
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Q27766319MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily
Q35848055MutY, an adenine glycosylase active on G-A mispairs, has homology to endonuclease III.
Q35855424Mutagenesis and repair in Bacillus anthracis: the effect of mutators
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Q74645632Mutation spectra of chemical mutagens determined by Lac+ reversion assay with Escherichia coli WP3101P-WP3106P tester strains
Q37019987Mutational spectrometry: a general approach for hot-spot point mutations in selectable genes
Q70759379Mutations in the mutY gene of Escherichia coli enhance the frequency of targeted G:C-->T:a transversions induced by a single 8-oxoguanine residue in single-stranded DNA
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Q46057951Mutators in Escherichia coli
Q35032008Near-ultraviolet mutagenesis in superoxide dismutase-deficient strains of Escherichia coli
Q46661085Neighboring base composition is strongly correlated with base substitution bias in a region of the chloroplast genome
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Q36141161Nucleotide sequence of the Escherichia coli micA gene required for A/G-specific mismatch repair: identity of micA and mutY
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Q37056557Organization of the bacterial chromosome
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Q33958486Spontaneous mutation in the Escherichia coli lacI gene
Q35544150Stationary phase mutagenesis: mechanisms that accelerate adaptation of microbial populations under environmental stress
Q35837084Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase
Q36131550Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations
Q89453864The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites
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Q42094076The Presence of the DNA Repair Genes mutM, mutY, mutL, and mutS is Related to Proteome Size in Bacterial Genomes.
Q35630875The Vsr endonuclease of Escherichia coli: an efficient DNA repair enzyme and a potent mutagen
Q47999082The YggX protein of Salmonella enterica is involved in Fe(II) trafficking and minimizes the DNA damage caused by hydroxyl radicals: residue CYS-7 is essential for YggX function
Q38319980The active site of the Escherichia coli MutY DNA adenine glycosylase
Q35140826The art and design of genetic screens: Escherichia coli
Q28143596The compositional evolution of vertebrate genomes
Q33559060The evolution of function within the Nudix homology clan
Q33992543The genes encoding formamidopyrimidine and MutY DNA glycosylases in Escherichia coli are transcribed as part of complex operons.
Q50913027The spontaneous mutation frequencies of Prochlorococcus strains are commensurate with those of other bacteria.
Q43182530The yeast rad18 mutator specifically increases G.C----T.A transversions without reducing correction of G-A or C-T mismatches to G.C pairs
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Q37381090Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY.
Q39503738Very-short-patch repair in Escherichia coli requires the dam adenine methylase
Q33910770mutA and mutC: two mutator loci in Escherichia coli that stimulate transversions
Q36223680mutM, a second mutator locus in Escherichia coli that generates G.C----T.A transversions

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