scholarly article | Q13442814 |
P50 | author | Tom K. Kerppola | Q38319401 |
P2093 | author name string | Huai Deng | |
P2860 | cites work | An integrated encyclopedia of DNA elements in the human genome | Q22122150 |
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region | Q24563505 | ||
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2 | Q24563807 | ||
Nrf2 regulates haematopoietic stem cell function | Q24604639 | ||
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain | Q24609907 | ||
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene | Q24649776 | ||
Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19 | Q27316136 | ||
Regulation of Drosophila metamorphosis by xenobiotic response regulators | Q27324641 | ||
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes | Q27861039 | ||
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray | Q28202142 | ||
Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2 | Q28382872 | ||
Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy | Q28579882 | ||
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds | Q28755952 | ||
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model | Q28910182 | ||
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression | Q29615644 | ||
Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation | Q29616037 | ||
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation | Q29618051 | ||
Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences | Q30484141 | ||
WAVE Forms Hetero- and Homo-oligomeric Complexes at Integrin Junctions in Drosophila Visualized by Bimolecular Fluorescence Complementation | Q30497636 | ||
Visualization of protein interactions in living Drosophila embryos by the bimolecular fluorescence complementation assay | Q30498214 | ||
Polytene chromosome squash methods for studying transcription and epigenetic chromatin modification in Drosophila using antibodies | Q33652253 | ||
Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity | Q33726669 | ||
Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains | Q33734064 | ||
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2 | Q33900511 | ||
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis | Q34146310 | ||
The eve stripe 2 enhancer employs multiple modes of transcriptional synergy | Q34371968 | ||
Role of antioxidants in paraquat toxicity | Q34904565 | ||
Transcriptional regulation of xenobiotic detoxification in Drosophila | Q35220210 | ||
A cis-regulatory map of the Drosophila genome. | Q35229726 | ||
Hormonal cross talk in insect development | Q35994193 | ||
Opposite orientations of a transcription factor heterodimer bind DNA cooperatively with interaction partners but have different effects on interferon-β gene transcription | Q36234728 | ||
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila | Q36481370 | ||
Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane | Q36557973 | ||
Cross-regulatory protein-protein interactions between Hox and Pax transcription factors | Q36869905 | ||
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice. | Q37214176 | ||
Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution | Q37830775 | ||
Nrf2: control of sensitivity to carcinogens | Q37849195 | ||
An overview of transcriptional regulation in response to toxicological insult. | Q38038498 | ||
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis | Q38358203 | ||
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival | Q38359163 | ||
A role for juvenile hormone in the prepupal development of Drosophila melanogaster | Q39513143 | ||
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice | Q40158424 | ||
Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head. | Q41757128 | ||
Krüppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster | Q41766039 | ||
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system | Q41962064 | ||
How does juvenile hormone control insect metamorphosis and reproduction? | Q42012655 | ||
Characterization of juvenile hormone epoxide hydrolase and related genes in the larval development of the silkworm Bombyx mori. | Q42020408 | ||
Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs. | Q42069589 | ||
Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation | Q42470857 | ||
Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole | Q42732652 | ||
EcR isoforms in Drosophila: testing tissue-specific requirements by targeted blockade and rescue | Q44238500 | ||
A cap 'n' collar protein isoform contains a selective Hox repressor function. | Q46732843 | ||
Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice | Q46974887 | ||
Subcellular localization and cytoplasmic complex status of endogenous Keap1. | Q46976303 | ||
Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila. | Q47072425 | ||
A comparative analysis of juvenile hormone metabolyzing enzymes in two species of Drosophila during development. | Q52199903 | ||
The effects of phenobarbital pretreatment on the metabolism and toxicity of paraoxon in the mouse. | Q52546531 | ||
Immunostaining of whole-mount imaginal discs. | Q52642615 | ||
Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex. | Q53616483 | ||
Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice. | Q54581515 | ||
P433 | issue | 16 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Drosophila | Q312154 |
P1104 | number of pages | 12 | |
P304 | page(s) | 3277-3288 | |
P577 | publication date | 2014-07-25 | |
P1433 | published in | Development | Q3025404 |
P1476 | title | Visualization of the Drosophila dKeap1-CncC interaction on chromatin illumines cooperative, xenobiotic-specific gene activation | |
P478 | volume | 141 |
Q46364818 | Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc |
Q41985716 | Dual Roles of Glutathione in Ecdysone Biosynthesis and Antioxidant Function During the Larval Development in Drosophila. |
Q51731708 | Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan. |
Q33763536 | Mechanisms and functions of Nrf2 signaling in Drosophila |
Q92476511 | Regulation of position effect variegation at pericentric heterochromatin by Drosophila Keap1-Nrf2 xenobiotic response factors |
Q26751266 | Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism |
Q41241392 | Visualization of the Genomic Loci That Are Bound by Specific Multiprotein Complexes by Bimolecular Fluorescence Complementation Analysis on Drosophila Polytene Chromosomes |
Q29248295 | Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster |