| P50 | author | Steven A Weinman | Q57569765 |
| P2093 | author name string | Hartmut Jaeschke | |
| | Anup Ramachandran | |
| | Margitta Lebofsky | |
| P2860 | cites work | Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging | Q28191739 |
| | Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression | Q28215218 |
| | Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase | Q28284593 |
| | Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse | Q28585450 |
| | Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice | Q28592978 |
| | Superoxide radical and superoxide dismutases | Q29614204 |
| | Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2(+/-) mice: two-stage oxidative injury | Q33336918 |
| | c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity | Q33912798 |
| | Invited review: manganese superoxide dismutase in disease | Q33944740 |
| | Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione | Q34218007 |
| | Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine | Q34294926 |
| | Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study | Q34471434 |
| | Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity. | Q34981041 |
| | Degradation of chromosomal DNA during apoptosis | Q35091420 |
| | The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity | Q35202851 |
| | Intracellular signaling mechanisms of acetaminophen-induced liver cell death | Q36263962 |
| | Protein oxidative damage is associated with life expectancy of houseflies | Q36458801 |
| | Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury | Q37506627 |
| | Molecular mechanisms of the hepatotoxicity caused by acetaminophen | Q38027602 |
| | Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury | Q38291198 |
| | Trovafloxacin, a fluoroquinolone antibiotic with hepatotoxic potential, causes mitochondrial peroxynitrite stress in a mouse model of underlying mitochondrial dysfunction | Q39676394 |
| | Selective protein covalent binding and target organ toxicity | Q41387154 |
| | Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure | Q41396770 |
| | Hepatic mitochondrial DNA depletion after an alcohol binge in mice: probable role of peroxynitrite and modulation by manganese superoxide dismutase | Q43218250 |
| | Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress | Q43673027 |
| | Enhanced acetaminophen hepatotoxicity in transgenic mice overexpressing BCL-2. | Q43771481 |
| | Identification of hepatic protein targets of the reactive metabolites of the non-hepatotoxic regioisomer of acetaminophen, 3'-hydroxyacetanilide, in the mouse in vivo using two-dimensional gel electrophoresis and mass spectrometry | Q43838611 |
| | Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? | Q43994104 |
| | Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: protection by glutathione | Q44186021 |
| | Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation | Q44527209 |
| | Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: roles of cytochrome c, Bax, Bid, and caspases | Q44567499 |
| | Scavenging peroxynitrite with glutathione promotes regeneration and enhances survival during acetaminophen-induced liver injury in mice | Q44572957 |
| | Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes | Q45108825 |
| | Use of isolated perfused organs in hypoxia and ischemia/reperfusion oxidant stress | Q45136664 |
| | Knockdown of superoxide dismutase 2 enhances acetaminophen-induced hepatotoxicity in rat. | Q45914369 |
| | Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen | Q46068587 |
| | Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity | Q46635865 |
| | c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity | Q46679597 |
| | Deoxyribonuclease 1 aggravates acetaminophen-induced liver necrosis in male CD-1 mice | Q46914171 |
| | Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2(+/-) mice | Q46916465 |
| | Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity | Q46974191 |
| | Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo | Q47953556 |
| | Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death | Q67485782 |
| | Acetaminophen-induced inhibition of hepatic mitochondrial respiration in mice | Q68355910 |
| | Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury | Q68628042 |
| | Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol | Q68637975 |
| | Acetaminophen-induced oxidation of protein thiols. Contribution of impaired thiol-metabolizing enzymes and the breakdown of adenine nucleotides | Q68708733 |
| | Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3'-hydroxyacetanilide, in mouse liver | Q69302284 |
| | Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8 | Q73128535 |
| | Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice | Q77381301 |
| | Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice | Q77419196 |
| | Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities | Q79410849 |
| | Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury | Q79967745 |
| | Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury | Q80077527 |
| P433 | issue | 3 | |
| P921 | main subject | manganese | Q731 |
| | hepatotoxicity | Q1349821 |
| | paracetamol | Q57055 |
| P304 | page(s) | 226-233 | |
| P577 | publication date | 2011-01-15 | |
| P1433 | published in | Toxicology and Applied Pharmacology | Q2446974 |
| P1476 | title | The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity | |
| P478 | volume | 251 | |