Hepatic cannabinoid receptor type 1 mediates alcohol-induced regulation of bile acid enzyme genes expression via CREBH.

scientific article

Hepatic cannabinoid receptor type 1 mediates alcohol-induced regulation of bile acid enzyme genes expression via CREBH. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2013PLoSO...868845C
P356DOI10.1371/JOURNAL.PONE.0068845
P932PMC publication ID3718807
P698PubMed publication ID23894352
P5875ResearchGate publication ID253336408

P2093author name stringHueng-Sik Choi
Won-Il Jeong
Tiangang Li
Chul-Ho Lee
Seung-Hoi Koo
Joseph Kwon
Yong-Hoon Kim
Don-Kyu Kim
Sung-Hoon Ahn
Dipanjan Chanda
John Y L Chiang
Jagannath Misra
Tae-Sik Park
Jung Ran Kim
P2860cites workEthanol has an acute effect on bile acid biosynthesis in manQ70138890
Liver lipid metabolismQ37162701
Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.Q37266999
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Effects of ethanol on bile acid and cholesterol metabolismQ40012124
Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemiaQ40282032
The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.Q40453939
The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolismQ41909224
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasisQ42103139
Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasisQ42526474
Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH.Q43106855
Binge drinking-induced liver injuryQ43279300
Involvement of endoplasmic reticulum stress in insulin resistance and diabetesQ45127777
Bile acid levels are increased in the liver of patients with steatohepatitisQ46604037
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liverQ46721570
Ethanol stimulates bile acid formation in primary human hepatocytesQ46919593
Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytesQ46959826
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory responseQ24304232
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesityQ24523292
ER stress controls iron metabolism through induction of hepcidinQ24630714
The endocannabinoid system as an emerging target of pharmacotherapyQ24648473
Activation of the peripheral endocannabinoid system in human obesityQ24655297
Leptin-regulated endocannabinoids are involved in maintaining food intakeQ28211969
Bile acids: trying to understand their chemistry and biology with the hope of helping patientsQ28238498
Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestineQ28242281
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
Cholestasis and alcoholic liver diseaseQ34210622
Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistanceQ34290823
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feedingQ34524224
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stressQ34801719
Bile acid regulation of gene expression: roles of nuclear hormone receptors.Q34803254
Ethanol promotes endoplasmic reticulum stress-induced neuronal death: involvement of oxidative stressQ34989703
Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytesQ35150049
Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesityQ35693984
Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in miceQ35870151
Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in miceQ36351511
From acute ER stress to physiological roles of the Unfolded Protein ResponseQ36362397
Activation of cannabinoid receptor type 1 (Cb1r) disrupts hepatic insulin receptor signaling via cyclic AMP-response element-binding protein H (Crebh)-mediated induction of Lipin1 gene.Q36368276
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesityQ36431832
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in miceQ36800423
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectcannabinoid receptorQ421237
cannabinoidsQ422936
CNR2Q17907844
P304page(s)e68845
P577publication date2013-07-22
P1433published inPLOS OneQ564954
P1476titleHepatic cannabinoid receptor type 1 mediates alcohol-induced regulation of bile acid enzyme genes expression via CREBH.
P478volume8

Reverse relations

cites work (P2860)
Q64229466Alcohol Induces More Severe Fatty Liver Disease by Influencing Cholesterol Metabolism
Q34121950Colonic inflammation and secondary bile acids in alcoholic cirrhosis
Q45067732Continued Alcohol Misuse in Human Cirrhosis is Associated with an Impaired Gut-Liver Axis
Q55080645Deficiency of cholesterol 7α-hydroxylase in bile acid synthesis exacerbates alcohol-induced liver injury in mice.
Q88924595Endocannabinoids in Body Weight Control
Q54948497Gut microbial composition can differentially regulate bile acid synthesis in humanized mice.
Q35653362Gut microbiota, cirrhosis, and alcohol regulate bile acid metabolism in the gut
Q42380618MitoNEET Deficiency Alleviates Experimental Alcoholic Steatohepatitis in Mice by Stimulating Endocrine Adiponectin-Fgf15 Axis
Q33779386Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice
Q37505719Orphan nuclear receptor Errγ induces C-reactive protein gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH.
Q37677097Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression
Q27693345Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective.
Q28086898Role of farnesoid X receptor and bile acids in alcoholic liver disease

Search more.