| scholarly article | Q13442814 |
| P2093 | author name string | Heisig P | |
| Tschorny R | |||
| P2860 | cites work | Protein measurement with the Folin phenol reagent | Q20900776 |
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| Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors | Q26778475 | ||
| Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria | Q28242053 | ||
| DNA topoisomerases | Q28264119 | ||
| A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli | Q28280711 | ||
| Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones. | Q33742392 | ||
| Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme | Q35059616 | ||
| Control of bacterial DNA supercoiling | Q35226989 | ||
| Mechanisms of quinolone resistance in Escherichia coli: characterization of nfxB and cfxB, two mutant resistance loci decreasing norfloxacin accumulation | Q35244676 | ||
| First clinical isolate of highly fluoroquinolone-resistant Escherichia coli in Scandanavia. | Q54313087 | ||
| Resistance to beta-lactam antibiotics and ciprofloxacin in gram-negative bacilli and staphylococci isolated from blood: a European collaborative study. European Study Group on Antibiotic Resistance. | Q54318566 | ||
| Escherichia coli cells resistant to the DNA gyrase inhibitor, ciprofloxacin, overproduce a 60 kD protein homologous to GroEL. | Q54329981 | ||
| New Escherichia coli gyrA and gyrB mutations which have a graded effect on DNA supercoiling. | Q54344061 | ||
| Frequency of appearance of resistant variants to norfloxacin and nalidixic acid | Q54475641 | ||
| Phenotypic characterization of quinolone-resistant mutants of Enterobacteriaceae selected from wild type, gyrA type and multiply-resistant (marA) type strains | Q59486251 | ||
| Role of the histone-like proteins OsmZ and HU in homologous recombination | Q67504431 | ||
| DNA supercoiling in Escherichia coli: topA mutations can be suppressed by DNA amplifications involving the tolC locus | Q69354160 | ||
| DNA topoisomerases | Q70095180 | ||
| Mapping the active site tyrosine of Escherichia coli DNA gyrase | Q70170795 | ||
| The determination of small quantities of bacteria by means of the biuret reaction | Q75998428 | ||
| Ciprofloxacin concentrations and impact of the colon microflora in patients undergoing colorectal surgery | Q35250995 | ||
| Endogenous active efflux of norfloxacin in susceptible Escherichia coli | Q35317399 | ||
| Development of resistance to nalidixic acid and the fluoroquinolones after the introduction of norfloxacin and ofloxacin | Q35319641 | ||
| The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans | Q35572870 | ||
| Rapid selection of organisms with increasing resistance on subinhibitory concentrations of norfloxacin in agar | Q35739909 | ||
| Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations | Q35810189 | ||
| Mutations in the gyrA gene of a highly fluoroquinolone-resistant clinical isolate of Escherichia coli | Q35811107 | ||
| Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus | Q35814875 | ||
| Escherichia coli K-12 tolF mutants: alterations in protein composition of the outer membrane | Q36601389 | ||
| Mechanisms of quinolone resistance in a clinical isolate of Escherichia coli highly resistant to fluoroquinolones but susceptible to nalidixic acid | Q36753126 | ||
| Use of a broad-host-range gyrA plasmid for genetic characterization of fluoroquinolone-resistant gram-negative bacteria | Q36755663 | ||
| Escherichia coli K-12 Mutants Resistant to Nalidixic Acid: Genetic Mapping and Dominance Studies | Q36817572 | ||
| Biology of bacterial deoxyribonucleic acid topoisomerases | Q37066515 | ||
| Laboratory survey of fluoroquinolone activity | Q37898069 | ||
| An Escherichia coli DNA topoisomerase I mutant has a compensatory mutation that alters two residues between functional domains of the DNA gyrase A protein | Q38328574 | ||
| Mechanisms of resistance to quinolones and clinical perspectives | Q38659740 | ||
| Mechanisms of action of and resistance to ciprofloxacin | Q39509001 | ||
| Fluorometric assay for fleroxacin uptake by bacterial cells | Q39814747 | ||
| Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli | Q39816339 | ||
| Norfloxacin resistance in a clinical isolate of Escherichia coli | Q39828952 | ||
| Differences in susceptibility to quinolones of outer membrane mutants of Salmonella typhimurium and Escherichia coli | Q39850992 | ||
| Genetic and biochemical characterization of norfloxacin resistance in Escherichia coli | Q39851107 | ||
| Isolation and characterization of norfloxacin-resistant mutants of Escherichia coli K-12. | Q39851366 | ||
| Novel gyrA point mutation in a strain of Escherichia coli resistant to fluoroquinolones but not to nalidixic acid | Q39866134 | ||
| In vitro antibacterial activities of tosufloxacin against and uptake of tosufloxacin by outer membrane mutants of Escherichia coli, Proteus mirabilis, and Salmonella typhimurium | Q39882625 | ||
| Limitations of plasmid complementation test for determination of quinolone resistance due to changes in the gyrase A protein and identification of conditional quinolone resistance locus | Q39883667 | ||
| DNA gyrase gyrA mutations in ciprofloxacin-resistant strains of Staphylococcus aureus: close similarity with quinolone resistance mutations in Escherichia coli | Q39952187 | ||
| Novel quinolone resistance mutations of the Escherichia coli DNA gyrase A protein: enzymatic analysis of the mutant proteins | Q40085874 | ||
| 4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction | Q40085967 | ||
| DNA gyrase on the bacterial chromosome: DNA cleavage induced by oxolinic acid | Q40260992 | ||
| Cloning and sequencing of the Escherichia coli gyrA gene coding for the A subunit of DNA gyrase | Q42648413 | ||
| Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes. | Q44244250 | ||
| The emergence of highly fluoroquinolone-resistant Escherichia coli in community-acquired urinary tract infections | Q44324064 | ||
| Nalidixic acid-resistant mutations of the gyrB gene of Escherichia coli | Q46102812 | ||
| Quinolone-resistant mutations of the gyrA gene of Escherichia coli | Q48332361 | ||
| High-level fluoroquinolone resistance in a Salmonella typhimurium isolate due to alterations in both gyrA and gyrB genes | Q50158766 | ||
| Isolation and characterization of a topA mutant of Shigella flexneri | Q50166730 | ||
| Osmotic regulation of porin expression: a role for DNA supercoiling | Q50194140 | ||
| An overlap between osmotic and anaerobic stress responses: a potential role for DNA supercoiling in the coordinate regulation of gene expression | Q50194798 | ||
| Ten-year survey of quinolone resistance in Escherichia coli causing urinary tract infections. | Q54241549 | ||
| Active efflux of ofloxacin by a highly quinolone-resistant strain of Proteus vulgaris | Q54284495 | ||
| A comparison of the mechanisms of decreased susceptibility of aztreonam-resistant and ceftazidime-resistant Enterobacteriaceae. | Q54311388 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Escherichia coli | Q25419 |
| P304 | page(s) | 1284-1291 | |
| P577 | publication date | 1994-06-01 | |
| P1433 | published in | Antimicrobial Agents and Chemotherapy | Q578004 |
| P1476 | title | Characterization of fluoroquinolone-resistant mutants of escherichia coli selected in vitro | |
| P478 | volume | 38 |
| Q54234724 | 4-Hydroxy-α-tetralone and its derivative as drug resistance reversal agents in multi drug resistant Escherichia coli. |
| Q57148574 | A Review of Scrub Typhus (Orientia tsutsugamushi and Related Organisms): Then, Now, and Tomorrow |
| Q35131092 | A novel, double mutation in DNA gyrase A of Escherichia coli conferring resistance to quinolone antibiotics. |
| Q39780047 | Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus |
| Q42906688 | Analysis of quinolone resistance mechanisms in Neisseria gonorrhoeae isolates in vitro |
| Q42861089 | Antibacterial activity of finafloxacin under different pH conditions against isogenic strains of Escherichia coli expressing combinations of defined mechanisms of fluoroquinolone resistance |
| Q47324867 | Antibiotics potentiating potential of catharanthine against superbug Pseudomonas aeruginosa. |
| Q33836664 | Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections. |
| Q33883639 | Broader distribution of plasmid-mediated quinolone resistance in the United States |
| Q64106427 | Changing paradigm of antibiotic resistance amongst Escherichia coli isolates in Indian pediatric population |
| Q36528206 | Characterization of clinical isolates of Escherichia coli showing high levels of fluoroquinolone resistance |
| Q36551331 | Clinical implications of reduced susceptibility to fluoroquinolones in paediatric Shigella sonnei and Shigella flexneri infections |
| Q38394500 | Collateral sensitivity of antibiotic-resistant microbes. |
| Q77712323 | Colonization and infection with fluoroquinolone-resistant Escherichia coli among cancer patients: clonal analysis |
| Q41810482 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials |
| Q39780359 | DNA gyrase gyrA mutations in quinolone-resistant clinical isolates of Pseudomonas aeruginosa |
| Q39469894 | Detection of gyrA mutations among 335 Pseudomonas aeruginosa strains isolated in Japan and their susceptibilities to fluoroquinolones |
| Q37511160 | Development and validation of a diagnostic DNA microarray to detect quinolone-resistant Escherichia coli among clinical isolates |
| Q36546371 | Development of a rapid assay for detecting gyrA mutations in Escherichia coli and determination of incidence of gyrA mutations in clinical strains isolated from patients with complicated urinary tract infections. |
| Q22122042 | Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria |
| Q34339497 | Dynamics of quinolone resistance in fecal Escherichia coli of finishing pigs after ciprofloxacin administration. |
| Q28378761 | Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis |
| Q33983331 | Emergence of reduced susceptibility and resistance to fluoroquinolones in Escherichia coli in Taiwan and contributions of distinct selective pressures |
| Q39860153 | Enhanced resistance to fluoroquinolones in laboratory-grown mutants & clinical isolates of Shigella due to synergism between efflux pump expression & mutations in quinolone resistance determining region |
| Q38837707 | Evolution of Drug Resistance in Bacteria |
| Q46862305 | Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase |
| Q40874282 | Gallic acid-based indanone derivative interacts synergistically with tetracycline by inhibiting efflux pump in multidrug resistant E. coli |
| Q33982113 | Genetic characterization of highly fluoroquinolone-resistant clinical Escherichia coli strains from China: role of acrR mutations |
| Q35123629 | Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli. |
| Q33976675 | Impact of gyrA and parC mutations on quinolone resistance, doubling time, and supercoiling degree of Escherichia coli. |
| Q36308072 | In vitro evaluation of the potential for resistance development to ceragenin CSA-13. |
| Q47135657 | Mechanisms of quinolone resistance in Escherichia coli isolated from companion animals, pet-owners, and non-pet-owners |
| Q40939781 | Mechanisms of resistance to fluoroquinolones: state-of-the-art 1992-1994. |
| Q36155441 | Mechanisms of resistance to quinolones |
| Q35122412 | Molecular epidemiology of fluoroquinolone-resistant Escherichia coli bloodstream isolates from patients admitted to European cancer centers |
| Q56610379 | Molecular mechanisms of resistance to antibiotics in Bartonella bacilliformis |
| Q39020968 | Mutation Supply and Relative Fitness Shape the Genotypes of Ciprofloxacin-Resistant Escherichia coli |
| Q36048167 | Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections. |
| Q33979064 | Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli |
| Q42743898 | Novel combination of mutations in the DNA gyrase and topoisomerase IV genes in laboratory-grown fluoroquinolone-resistant Shigella flexneri mutants. |
| Q42583041 | Pharmacodynamic modeling of in vitro activity of marbofloxacin against Escherichia coli strains. |
| Q64092139 | Phenotypic and genotypic characteristics of with non-susceptibility to quinolones isolated from environmental samples on pig farms |
| Q34019104 | Plasmidic qnrA3 enhances Escherichia coli fitness in absence of antibiotic exposure |
| Q89591629 | Population bottlenecks strongly influence the evolutionary trajectory to fluoroquinolone resistance in Escherichia coli |
| Q38649580 | Prediction of antibiotic resistance: time for a new preclinical paradigm? |
| Q41454301 | Quantitative contributions of target alteration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance |
| Q35111896 | Relationship between quinolone use and emergence of ciprofloxacin-resistant Escherichia coli in bloodstream infections |
| Q35116590 | Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance |
| Q57748499 | Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase |
| Q41788804 | Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli |
| Q35132378 | The population dynamics of antimicrobial chemotherapy. |
| Q37203095 | The use of platensimycin and platencin to fight antibiotic resistance |
| Q37612974 | Tigecycline Nonsusceptibility Occurs Exclusively in Fluoroquinolone-Resistant Escherichia coli Clinical Isolates, Including the Major Multidrug-Resistant Lineages O25b:H4-ST131-H30R and O1-ST648. |
| Q91724536 | Usnic acid modifies MRSA drug resistance through down-regulation of proteins involved in peptidoglycan and fatty acid biosynthesis |
| Q33699643 | gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae |
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