Heterogeneity in Pseudomonas aeruginosa biofilms includes expression of ribosome hibernation factors in the antibiotic-tolerant subpopulation and hypoxia-induced stress response in the metabolically active population

scientific article published on 17 February 2012

Heterogeneity in Pseudomonas aeruginosa biofilms includes expression of ribosome hibernation factors in the antibiotic-tolerant subpopulation and hypoxia-induced stress response in the metabolically active population is …
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scholarly articleQ13442814

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P356DOI10.1128/JB.00022-12
P932PMC publication ID3318454
P698PubMed publication ID22343293
P5875ResearchGate publication ID221840848

P2093author name stringBetsey Pitts
Philip S Stewart
Kathleen McInnerney
Kerry S Williamson
Michael J Franklin
Ailyn C Perez-Osorio
Lee A Richards
P2860cites workExtracellular DNA Required for Bacterial Biofilm FormationQ22065541
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Clustering of Pseudomonas aeruginosa transcriptomes from planktonic cultures, developing and mature biofilms reveals distinct expression profilesQ33247985
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Heterogeneous rpoS and rhlR mRNA levels and 16S rRNA/rDNA (rRNA gene) ratios within Pseudomonas aeruginosa biofilms, sampled by laser capture microdissectionQ33546954
Spatial patterns of alkaline phosphatase expression within bacterial colonies and biofilms in response to phosphate starvationQ33707879
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Physiology of Pseudomonas aeruginosa in biofilms as revealed by transcriptome analysis.Q33749041
Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacinQ33979968
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Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genesQ34757004
The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress.Q34941745
Noise-based switches and amplifiers for gene expressionQ35047931
Nonuniform spatial patterns of respiratory activity within biofilms during disinfection.Q35184620
Degradation of stable RNA in bacteriaQ35207031
Characterization of colony morphology variants isolated from Streptococcus pneumoniae biofilmsQ35759418
Characterization of a Pseudomonas putida rough variant evolved in a mixed-species biofilm with Acinetobacter sp. strain C6.Q35879451
Vibrio cholerae O1 El Tor: identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formationQ36456326
Self-generated diversity produces "insurance effects" in biofilm communitiesQ37621081
Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coliQ37663571
Bistability and biofilm formation in Bacillus subtilisQ39257013
Genotypic and phenotypic variation in Pseudomonas aeruginosa reveals signatures of secondary infection and mutator activity in certain cystic fibrosis patients with chronic lung infectionsQ39656697
Enhanced activity of combination of tobramycin and piperacillin for eradication of sessile biofilm cells of Pseudomonas aeruginosaQ39816719
Tobramycin resistance of Pseudomonas aeruginosa cells growing as a biofilm on urinary catheter materialQ39849725
Stratified growth in Pseudomonas aeruginosa biofilmsQ40172940
Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis.Q40624126
Oxygen limitation contributes to antibiotic tolerance of Pseudomonas aeruginosa in biofilms.Q40968095
A Tn7-based broad-range bacterial cloning and expression systemQ41458282
Interrelationships between colonies, biofilms, and planktonic cells of Pseudomonas aeruginosaQ41807621
Relative and Absolute Quantitative Real-Time PCR-Based Quantifications of hcnC and phlD Gene Transcripts in Natural Soil Spiked with Pseudomonas sp. Strain LBUM300Q42001432
Transcription level of messenger RNA per gene copy determined with dual-spike-in strategyQ42024448
Characterization of in vitro biofilm-associated pneumococcal phase variants of a clinically relevant serotype 3 cloneQ42912686
Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms.Q42957523
Gene expression in Pseudomonas aeruginosa biofilmsQ43777487
The Pseudomonas aeruginosa RpoS regulon and its relationship to quorum sensing.Q44756516
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytesQ46149392
Effect of pH on the antimicrobial susceptibility of planktonic and biofilm-grown clinical Pseudomonas aeruginosa isolates.Q46971285
Activities of Escherichia coli ribosomes in IF3 and RMF change to prepare 100S ribosome formation on entering the stationary growth phase.Q54410274
Distinct activities of Escherichia coli small heat shock proteins IbpA and IbpB promote efficient protein disaggregation.Q54412070
Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosisQ73335181
Strain-specific proteome responses of Pseudomonas aeruginosa to biofilm-associated growth and to calciumQ81535144
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectantibioticQ12187
Pseudomonas aeruginosaQ31856
hypoxiaQ105688
hibernationQ159408
biofilmQ467410
P304page(s)2062-2073
P577publication date2012-02-17
P1433published inJournal of BacteriologyQ478419
P1476titleHeterogeneity in Pseudomonas aeruginosa biofilms includes expression of ribosome hibernation factors in the antibiotic-tolerant subpopulation and hypoxia-induced stress response in the metabolically active population
P478volume194

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