| scholarly article | Q13442814 |
| P50 | author | Shigeo Murata | Q55186538 |
| Akihiro Kikuchi | Q64167480 | ||
| P2093 | author name string | Keiji Tanaka | |
| Fei Lan | |||
| Tsuguhito Ota | |||
| Shoichi Iseki | |||
| Hiroaki Takayama | |||
| Shuichi Kaneko | |||
| Toshinari Takamura | |||
| Hirofumi Misu | |||
| Yuki Kita | |||
| Yumie Takeshita | |||
| Miyuki Yamamoto | |||
| Hiroto Hayashi | |||
| Kazuhide Ishikura | |||
| Seiichiro Kurita | |||
| Takashi Takeda | |||
| Kosuke R Shima | |||
| Kaito Iwayama | |||
| Masafumi Uno | |||
| Toshiki Otoda | |||
| Takehiro Kanamori | |||
| Ken-ichiro Kato | |||
| Kunpei Tokuyama | |||
| P2860 | cites work | The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis. | Q51567705 |
| Impaired immunoproteasome assembly and immune responses in PA28-/- mice. | Q52537275 | ||
| Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney | Q73117350 | ||
| Growth retardation in mice lacking the proteasome activator PA28gamma | Q73297649 | ||
| Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 | ||
| Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress | Q24296668 | ||
| Inflammation, stress, and diabetes | Q24523336 | ||
| Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation | Q24673179 | ||
| Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis | Q28143710 | ||
| Expression and subcellular localization of mouse 20S proteasome activator complex PA28 | Q28248267 | ||
| Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta. | Q28363065 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria | Q28573343 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
| Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
| The 26S proteasome: a molecular machine designed for controlled proteolysis | Q29619692 | ||
| Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response | Q33264844 | ||
| Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes. | Q33267520 | ||
| Hyperglycemia impairs proteasome function by methylglyoxal | Q33688582 | ||
| The proteasome, a novel protease regulated by multiple mechanisms | Q33700949 | ||
| Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation | Q33755125 | ||
| Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. | Q33896647 | ||
| Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity | Q34181503 | ||
| Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting. | Q34395323 | ||
| β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency | Q34448671 | ||
| Enhancement of proteasome function by PA28α overexpression protects against oxidative stress. | Q34592321 | ||
| Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans | Q34615491 | ||
| The unfolded protein response in nutrient sensing and differentiation | Q34664763 | ||
| Transcriptional and translational control in the Mammalian unfolded protein response | Q34762452 | ||
| Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice | Q35187068 | ||
| Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation. | Q35612368 | ||
| Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII. | Q35821221 | ||
| Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents | Q36183590 | ||
| Brown rice and its component, γ-oryzanol, attenuate the preference for high-fat diet by decreasing hypothalamic endoplasmic reticulum stress in mice. | Q36410722 | ||
| Selective versus total insulin resistance: a pathogenic paradox | Q37076798 | ||
| Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase | Q37314375 | ||
| Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins | Q37535142 | ||
| A liver-derived secretory protein, selenoprotein P, causes insulin resistance. | Q39638094 | ||
| Preliminary report: inhibition of cellular proteasome activity by free fatty acids | Q39855345 | ||
| Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome | Q40115986 | ||
| Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion | Q40303586 | ||
| Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts | Q40575367 | ||
| Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28. | Q40851962 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling | Q42800302 | ||
| Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway | Q43690470 | ||
| Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients. | Q45009688 | ||
| Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo | Q45045429 | ||
| Involvement of endoplasmic reticulum stress in insulin resistance and diabetes | Q45127777 | ||
| Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning | Q45728735 | ||
| Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 | ||
| Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients | Q46322589 | ||
| Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity | Q46473862 | ||
| Stressed out about obesity and insulin resistance | Q46883060 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported | Q19125045 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | obesity | Q12174 |
| insulin resistance | Q1053470 | ||
| endoplasmic reticulum | Q79927 | ||
| P1104 | number of pages | 14 | |
| P304 | page(s) | 811-824 | |
| P577 | publication date | 2012-12-03 | |
| P1433 | published in | Diabetes | Q895262 |
| P1476 | title | Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver | |
| P478 | volume | 62 |
| Q48211716 | Aortic dysfunction in metabolic syndrome mediated by perivascular adipose tissue TNFα and NOX2 dependent pathway |
| Q37433001 | Association of obesity with proteasomal gene polymorphisms in children |
| Q48106093 | Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. |
| Q91801159 | Cellular Responses to Proteasome Inhibition: Molecular Mechanisms and Beyond |
| Q49069786 | Cellular senescence: Implications for metabolic disease |
| Q40564967 | Changes in glucose transporter expression and nitric oxide production are associated with liver injury in diabetes |
| Q28251174 | Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes |
| Q34449244 | Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity |
| Q49520691 | Effect of Fish Oil vs. Resolvin D1, E1, Methyl Esters of Resolvins D1 or D2 on Diabetic Peripheral Neuropathy |
| Q35867508 | Effect of enriching the diet with menhaden oil or daily treatment with resolvin D1 on neuropathy in a mouse model of type 2 diabetes. |
| Q38923148 | Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view |
| Q92369782 | Exercise training prevents the perivascular adipose tissue-induced aortic dysfunction with metabolic syndrome |
| Q37625006 | Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome |
| Q51736974 | High-Fructose Consumption Impairs the Redox System and Protein Quality Control in the Brain of Syrian Hamsters: Therapeutic Effects of Melatonin. |
| Q64890389 | High-carb or low-carb, that is a question. |
| Q90406900 | Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation |
| Q42806806 | Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes |
| Q59127969 | Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes |
| Q36635306 | Impact of ER protein homeostasis on metabolism |
| Q38210860 | Impaired proteostasis: role in the pathogenesis of diabetes mellitus |
| Q91711447 | Inflammatory Signaling and Brown Fat Activity |
| Q52622038 | Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples. |
| Q90377509 | Involvement of sarco/endoplasmic reticulum calcium ATPase-mediated calcium flux in the protective effect of oleic acid against lipotoxicity in hepatocytes |
| Q55548365 | JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies. |
| Q49843619 | Liver function and dysfunction - a unique window into the physiological reach of ER stress and the unfolded protein response |
| Q30009308 | Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression |
| Q36951713 | Nitric oxide differentially affects proteasome activator 28 after arterial injury in type 1 and type 2 diabetic rats |
| Q64067884 | Obesity May Accelerate the Aging Process |
| Q37497314 | Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma. |
| Q36302442 | PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection |
| Q54957638 | Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress. |
| Q36010708 | Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity |
| Q36713798 | Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility |
| Q35123951 | Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets |
| Q48286906 | Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice. |
| Q64965104 | Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes. |
| Q48409756 | Sodium 4-Phenylbutyrate Attenuates Myocardial Reperfusion Injury by Reducing the Unfolded Protein Response |
| Q46355679 | The Pathogenesis of Obesity-Associated Adipose Tissue Inflammation |
| Q37269271 | The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy |
| Q37695350 | The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes |
| Q52568660 | Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline. |
| Q88771047 | p62-mediated autophagy affects nutrition-dependent insulin receptor substrate 1 dynamics in 3T3-L1 preadipocytes |
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