Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes.

scientific article published on 24 August 2015

Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1681/ASN.2015020191
P932PMC publication ID4814187
P698PubMed publication ID26303067

P50authorGilbert W MoeckelQ77628695
P2093author name stringHossam Hassan
Chang Liu
Stefan Somlo
Ann-Hwee Lee
Keita Soda
Shuta Ishibe
Xuefei Tian
Kazunori Inoue
Sorin Fedeles
Alda Tufro
Nathan Chai
P2860cites workRole of the endoplasmic reticulum unfolded protein response in glomerular epithelial cell injuryQ46465778
Involvement of endoplasmic reticulum (ER) stress in podocyte injury induced by excessive protein accumulationQ46826531
Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocyte-specific injury.Q51531177
Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes.Q52616889
Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.Q53661064
mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome.Q54351691
Podocyte-specific expression of cre recombinase in transgenic miceQ57740867
A pathogenic role for JNK signaling in experimental anti-GBM glomerulonephritisQ80540602
WT1 activates a glomerular-specific enhancer identified from the human nephrin geneQ80907733
Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1Q86412807
ER stress triggers MCP-1 expression through SET7/9-induced histone methylation in the kidneys of db/db miceQ87146747
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stressQ24291026
Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cellsQ24306519
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymeraseQ28302692
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formationQ28590393
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICEQ29619356
Role of dynamin, synaptojanin, and endophilin in podocyte foot processesQ30530966
Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.Q30572680
Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagyQ33646704
Inhibition of podocyte FAK protects against proteinuria and foot process effacement.Q35153198
Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out miceQ35709954
Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severityQ35719978
Increased tubular proliferation as an adaptive response to glomerular albuminuriaQ35804206
Endoplasmic reticulum stress sensing in the unfolded protein responseQ36626672
Laminin β2 gene missense mutation produces endoplasmic reticulum stress in podocytesQ37078425
Endoplasmic reticulum stress as a progression factor for kidney injuryQ37666123
PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegenerationQ37822920
The intersecting roles of endoplasmic reticulum stress, ubiquitin- proteasome system, and autophagy in the pathogenesis of proteinuric kidney diseaseQ38068781
Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potentialQ38198491
Proteostasis in endoplasmic reticulum--new mechanisms in kidney diseaseQ38206090
Evidence for activation of the unfolded protein response in collagen IV nephropathiesQ38311017
Survival and death of endoplasmic-reticulum-stressed cells: Role of autophagyQ38833593
Regulation of CD2-associated protein influences podocyte endoplasmic reticulum stress-mediated apoptosis induced by albumin overloadQ39523359
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging miceQ39812158
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in miceQ41912848
Podocyte Injury Associated with Mutant α-Actinin-4Q42844049
Glomerular epithelial cell injury associated with mutant alpha-actinin-4.Q45916571
Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetesQ46275218
P4510describes a project that usesImageJQ1659584
P433issue4
P921main subjectendoplasmic reticulumQ79927
P304page(s)1055-1065
P577publication date2015-08-24
P1433published inJournal of the American Society of NephrologyQ17123893
P1476titleEssential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes
P478volume27

Reverse relations

cites work (P2860)
Q37223452Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models
Q58693568Comparative Analysis of Podocyte Foot Process Morphology in Three Species by 3D Super-Resolution Microscopy
Q47177962DEV induce autophagy via the endoplasmic reticulum stress related unfolded protein response.
Q41813833Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy
Q58798920Duck enteritis virus activates CaMKKβ-AMPK to trigger autophagy in duck embryo fibroblast cells via increased cytosolic calcium
Q47239353Endoplasmic reticulum stress in the pathogenesis of fibrotic disease
Q47711878Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases
Q90068105Inhibition of Endocytosis of Clathrin-Mediated Angiotensin II Receptor Type 1 in Podocytes Augments Glomerular Injury
Q36355151Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response.
Q36819483Newcastle disease virus NP and P proteins induce autophagy via the endoplasmic reticulum stress-related unfolded protein response
Q91675723Podocyte histone deacetylase activity regulates murine and human glomerular diseases
Q90636660Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation

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