Cardiogenic differentiation and transdifferentiation of progenitor cells

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Cardiogenic differentiation and transdifferentiation of progenitor cells is …
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scholarly articleQ13442814

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P356DOI10.1161/CIRCRESAHA.108.180588
P932PMC publication ID2748983
P698PubMed publication ID18988903

P50authorMichael A. LaflammeQ39673791
P2093author name stringHans Reinecke
Elina Minami
Wei-Zhong Zhu
P2860cites workRegenerating the heartQ22251075
MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortexQ24563497
Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heartQ24606117
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cellsQ24616059
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cellsQ24672061
Induced pluripotent stem cell lines derived from human somatic cellsQ27860597
Establishment in culture of pluripotential cells from mouse embryosQ27860625
Multilineage potential of adult human mesenchymal stem cellsQ27860737
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsQ27860937
Induction of pluripotent stem cells from adult human fibroblasts by defined factorsQ27860967
Embryonic Stem Cell Lines Derived from Human BlastocystsQ27861010
Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytesQ28209232
Bone marrow cells regenerate infarcted myocardiumQ28210640
Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscleQ28240311
Reprogramming of human somatic cells to pluripotency with defined factorsQ28262710
Chimerism of the Transplanted HeartQ77452324
Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human heartsQ77885470
A Cre-loxP based system for studying horizontal gene transferQ80419816
Isolation and expansion of adult cardiac stem cells from human and murine heartQ80837204
Cardiac stem cells in the real worldQ80842631
Human cord blood cells induce angiogenesis following myocardial infarction in NOD/scid-miceQ81526279
Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvementQ83043116
Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarctionQ83697673
The significant cardiomyogenic potential of human umbilical cord blood-derived mesenchymal stem cells in vitroQ50684064
Human cord blood CD133+ cells immunoselected by a clinical-grade apparatus differentiate in vitro into endothelial- and cardiomyocyte-like cellsQ50705076
Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathyQ51371194
Extracardiac progenitor cells repopulate most major cell types in the transplanted human heartQ51833240
Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approachQ51996048
Cardiac and Extracardiac Expression of Csx/Nkx2.5 Homeodomain ProteinQ52187531
Expression of the T-box family genes, Tbx1-Tbx5, during early mouse developmentQ52200425
Magnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heart.Q53493162
Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts.Q53518426
Effects of bone marrow derived mesenchymal stem cells transplantation in acutely infarcting myocardiumQ53614409
Cardiac progenitor cells in brown adipose tissue repaired damaged myocardiumQ54457409
Bioenergetic and Functional Consequences of Bone Marrow-Derived Multipotent Progenitor Cell Transplantation in Hearts With Postinfarction Left Ventricular RemodelingQ56777840
Genetic Proof-of-Concept for Cardiac Gene Expression in Human Circulating Blood-Derived Progenitor CellsQ58816187
Notch Signaling Contributes to the Expression of Cardiac Markers in Human Circulating Progenitor CellsQ58816239
Cell-to-Cell Connection of Endothelial Progenitor Cells With Cardiac Myocytes by NanotubesQ58816268
Differentiation of circulating endothelial progenitor cells to a cardiomyogenic phenotype depends on E-cadherinQ58816270
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarctsQ59064540
Transdifferentiation of Blood-Derived Human Adult Endothelial Progenitor Cells Into Functionally Active CardiomyocytesQ60723059
Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal propertiesQ62704063
Cardiomyocyte transplantation improves heart functionQ71476830
Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendantsQ72678188
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted heartsQ73791469
Does transplantation of cardiomyocytes improve function of infarcted myocardium?Q73914632
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularizationQ77323614
Human umbilical cord blood-derived CD133+ cells enhance function and repair of the infarcted myocardiumQ48944721
Troponin I gene expression during human cardiac development and in end-stage heart failureQ28268307
Human mesenchymal stem cells modulate allogeneic immune cell responsesQ28288692
Isolation of putative progenitor endothelial cells for angiogenesisQ28302884
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineagesQ28306800
Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytesQ28345594
Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repairQ28587325
Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factorsQ28588872
GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesodermQ28594534
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived populationQ29616533
Adult cardiac stem cells are multipotent and support myocardial regenerationQ29620122
Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat heartsQ29620480
Autologous transplantation of bone marrow cells improves damaged heart functionQ30815113
Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularizationQ30876047
Physiological Coupling of Donor and Host Cardiomyocytes After Cellular TransplantationQ31141231
Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiationQ33202256
CD31- but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiationQ33216802
Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cellsQ33226565
No evidence of transdifferentiation of human endothelial progenitor cells into cardiomyocytes after coculture with neonatal rat cardiomyocytesQ33235640
Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivoQ33270812
Bone marrow cells adopt the cardiomyogenic fate in vivoQ33304156
Lineage tracing of cardiac explant derived cells.Q33328467
Adult bone marrow-derived cells do not acquire functional attributes of cardiomyocytes when transplanted into peri-infarct myocardiumQ33330259
Cardiomyocytes can be generated from marrow stromal cells in vitroQ33843659
Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineagesQ33862841
Myosin isoforms, muscle fiber types, and transitionsQ33918690
Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac functionQ33928468
Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult heartsQ34226034
Desmin: a major intermediate filament protein essential for the structural integrity and function of muscleQ34361378
Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac graftsQ34387398
Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes.Q34478174
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat heartsQ34508414
The role of the sca-1+/CD31- cardiac progenitor cell population in postinfarction left ventricular remodelingQ34513743
Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injuryQ34657173
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophyQ35918432
Human cardiac stem cellsQ35956924
Human embryonic stem cell transplantation to repair the infarcted myocardiumQ36025653
Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissuesQ36220146
Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiationQ36220944
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarctionQ36349782
The production and directed differentiation of human embryonic stem cells.Q36376692
A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potentialQ36399846
Plasticity and tissue regenerative potential of bone marrow-derived cellsQ36667445
Concise review: stem cell antigen-1: expression, function, and enigma.Q36767396
Extra-atrial expression of the gene for atrial natriuretic factor.Q37398504
Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cellsQ38292474
Transgenic enrichment of cardiomyocytes from human embryonic stem cellsQ40076187
Identification and selection of cardiomyocytes during human embryonic stem cell differentiationQ40145603
Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response.Q40173892
Niche-dependent translineage commitment of endothelial progenitor cells, not cell fusion in general, into myocardial lineage cellsQ40429287
Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterizationQ40641800
Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cellsQ40648427
Cardiomyocyte differentiation of mouse and human embryonic stem cellsQ40729330
Circulating endothelial precursors: mystery, reality, and promiseQ40741679
Transplantation of bone marrow-derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarctionQ41829084
Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycleQ42916219
Monoclonal antibodies to the muscle isoform of alpha-actinin--a marker for the study of the differentiation of skeletal and cardiac musclesQ43611556
Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effectsQ43697103
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cellsQ44145594
TNF-alpha plus IFN-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responsesQ44285411
Cell fusion is the principal source of bone-marrow-derived hepatocytesQ44383220
Growth and differentiation of rat bone marrow stromal cells: does 5-azacytidine trigger their cardiomyogenic differentiation?Q44448228
Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiationQ44592644
Spontaneous cardiomyocyte differentiation from adipose tissue stroma cellsQ44680903
Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cellsQ45098355
Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia modelQ45218845
The post-natal heart contains a myocardial stem cell population.Q45855585
Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selectionQ45864313
Transplantation of fetal myocardial tissue into the infarcted myocardium of rat. A potential method for repair of infarcted myocardium?Q45879469
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardiumQ46057122
Thymidine analogs are transferred from prelabeled donor to host cells in the central nervous system after transplantation: a word of cautionQ46864866
Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats.Q47575065
Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heartQ47611450
Evidence for circulating bone marrow-derived endothelial cellsQ47612637
Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cellsQ47820046
Evidence for fusion between cardiac and skeletal muscle cellsQ47999205
Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesisQ48132703
Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.Q48414650
Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and gliaQ48460765
Dose-dependent contribution of CD34-positive cell transplantation to concurrent vasculogenesis and cardiomyogenesis for functional regenerative recovery after myocardial infarctionQ48619654
Cell transplantation preserves cardiac function after infarction by infarct stabilization: augmentation by stem cell factor.Q48943611
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)1058-1071
P577publication date2008-11-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inCirculation ResearchQ2599020
P1476titleCardiogenic differentiation and transdifferentiation of progenitor cells
P478volume103

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