| scholarly article | Q13442814 |
| P50 | author | Cintia Sade de Paiva | Q44473623 |
| P2093 | author name string | Stephen C Pflugfelder | |
| Rosa M Corrales | |||
| P2860 | cites work | Circulating Th17, Th22, and Th1 cells are increased in psoriasis | Q24629315 |
| Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages | Q24642180 | ||
| Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling | Q24647357 | ||
| Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells | Q27860460 | ||
| IL-17 and Th17 Cells | Q27860566 | ||
| The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells | Q27860620 | ||
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| IL-17: prototype member of an emerging cytokine family | Q28214946 | ||
| Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice | Q79445122 | ||
| Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress | Q80382639 | ||
| Autoimmune diseases are connected with disturbances in cytokine synthesis, and therapy with IFN-gamma blockers is their main pathogenetic treatment | Q81038371 | ||
| [Neutralisation of interferon gamma--a new trend in therapy of rheumatoid arthritis] | Q81551541 | ||
| Treatment of alopecia areata with anti-interferon-gamma antibodies | Q82217444 | ||
| IL-8 and IFN-gamma in tear fluid of patients with cystic fibrosis | Q82598340 | ||
| Implications of immunomodulatory interleukins for the hyperimmunoglobulinemia of Sjögren's syndrome | Q84091899 | ||
| Anticytokine therapy, particularly anti-IFN-gamma, in Th1-mediated autoimmune diseases | Q84240200 | ||
| Proinflammatory cytokine profiling of tears from dry eye patients by means of antibody microarrays | Q84579952 | ||
| Expression of interleukin-17 in autoimmune dacryoadenitis in MRL/lpr mice | Q85061502 | ||
| CD8⁺ cells regulate the T helper-17 response in an experimental murine model of Sjögren syndrome | Q37407580 | ||
| Induction of Th17 differentiation by corneal epithelial-derived cytokines | Q37462911 | ||
| Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity | Q37825597 | ||
| Th22 in inflammatory and autoimmune disease: prospects for therapeutic intervention | Q37850717 | ||
| TH17 and TH22 cells: a confusion of antimicrobial response with tissue inflammation versus protection. | Q38015504 | ||
| Ocular surface inflammation is regulated by innate immunity | Q38021235 | ||
| Th22 and related cytokines in inflammatory and autoimmune diseases | Q38068964 | ||
| Innate lymphoid cells: from border protection to the initiation of inflammatory diseases | Q38077406 | ||
| ESAT-6- and CFP-10-specific Th1, Th22 and Th17 cells in tuberculous pleurisy may contribute to the local immune response against Mycobacterium tuberculosis infection | Q39373309 | ||
| Activation of AMP-activated protein kinase by adiponectin rescues salivary gland epithelial cells from spontaneous and interferon-gamma-induced apoptosis | Q39746363 | ||
| Salivary gland tissue expression of interleukin-23 and interleukin-17 in Sjögren's syndrome: findings in humans and mice | Q39912433 | ||
| Identification of IL-18 and Th17 cells in salivary glands of patients with Sjögren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18. | Q39953212 | ||
| Interferon-gamma induces apoptosis and expression of inflammation-related proteins in Chang conjunctival cells. | Q40930968 | ||
| Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndrome | Q40972080 | ||
| Regulation of human leukocyte antigen expression in human conjunctival epithelium | Q40980938 | ||
| The expanding universe of T-cell subsets: Th1, Th2 and more. | Q41120396 | ||
| A unifying model of the immunoregulatory role of the interferon system: can interferon produce disease in humans? | Q41249397 | ||
| Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13. | Q42173370 | ||
| No consequences of dietary n-3 polyunsaturated fatty acid deficiency on the severity of scopolamine-induced dry eye. | Q42777937 | ||
| Transforming growth factor-beta induces development of the T(H)17 lineage | Q28237370 | ||
| The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation | Q28266133 | ||
| Suppression of interleukin 1alpha and interleukin 1beta in human limbal epithelial cells cultured on the amniotic membrane stromal matrix | Q28361114 | ||
| SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production | Q28507392 | ||
| The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium | Q28591094 | ||
| NK cells promote Th-17 mediated corneal barrier disruption in dry eye | Q28730069 | ||
| IL-23 drives a pathogenic T cell population that induces autoimmune inflammation | Q29547525 | ||
| Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins | Q29547534 | ||
| TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties | Q29547848 | ||
| A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 | Q29547855 | ||
| IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells | Q29616148 | ||
| IL-17 family cytokines and the expanding diversity of effector T cell lineages | Q29619361 | ||
| Apical corneal barrier disruption in experimental murine dry eye is abrogated by methylprednisolone and doxycycline | Q30818365 | ||
| TH17, TH22 and Treg cells are enriched in the healthy human cecum | Q31076852 | ||
| Flow cytometric analysis of inflammatory markers in KCS: 6-month treatment with topical cyclosporin A. | Q31775977 | ||
| Th17 cells: effector T cells with inflammatory properties | Q33732092 | ||
| Unraveling the pathophysiology of Sjogren syndrome-associated dry eye disease | Q33819490 | ||
| Tear cytokine and chemokine analysis and clinical correlations in evaporative-type dry eye disease | Q33869200 | ||
| Effect of pro-inflammatory mediators on membrane-associated mucins expressed by human ocular surface epithelial cells | Q33894453 | ||
| Desiccating stress promotion of Th17 differentiation by ocular surface tissues through a dendritic cell-mediated pathway | Q33938235 | ||
| Improved transduction of human corneal epithelial progenitor cells with cell-targeting adenoviral vectors | Q34004280 | ||
| Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice | Q34019278 | ||
| Spontaneous autoimmune dacryoadenitis in aged CD25KO mice | Q34033436 | ||
| Disruption of TGF-β signaling improves ocular surface epithelial disease in experimental autoimmune keratoconjunctivitis sicca | Q34110644 | ||
| Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. | Q34285649 | ||
| The treatment of dry eye. | Q34391944 | ||
| Colitis and intestinal inflammation in IL10-/- mice results from IL-13Rα2-mediated attenuation of IL-13 activity. | Q34427654 | ||
| Th22 cells as well as Th17 cells expand differentially in patients with early-stage and late-stage myelodysplastic syndrome | Q34510880 | ||
| Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome-like autoimmune exocrinopathy | Q34600485 | ||
| Dry eye as a mucosal autoimmune disease | Q34647761 | ||
| Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses | Q34731337 | ||
| CD4 T cells: fates, functions, and faults | Q34813153 | ||
| Interferon-γ-secreting NK cells promote induction of dry eye disease | Q35001933 | ||
| Pharmacological cholinergic blockade stimulates inflammatory cytokine production and lymphocytic infiltration in the mouse lacrimal gland | Q35027540 | ||
| Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye | Q35083557 | ||
| CCL20, γδ T cells, and IL-22 in corneal epithelial healing | Q35105392 | ||
| The IL-23/IL-17 axis in inflammation | Q42825302 | ||
| Th17 cells in inflammatory conditions | Q42976492 | ||
| Salivary gland and peripheral blood T helper 1 and 2 cell activity in Sjögren's syndrome compared with non-Sjögren's sicca syndrome. | Q43049433 | ||
| The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut. | Q43095069 | ||
| Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease | Q43723395 | ||
| Flow cytometric analysis of the inflammatory marker HLA DR in dry eye syndrome: results from 12 months of randomized treatment with topical cyclosporin A. | Q44339254 | ||
| CD4+ Th2 cells function alike effector Tr1 and Th1 cells through the deletion of a single cytokine IL-6 and IL-10 gene | Q44558146 | ||
| Antiinflammatory therapy for dry eye. | Q44763839 | ||
| Topical cyclosporine inhibits conjunctival epithelial apoptosis in experimental murine keratoconjunctivitis sicca | Q45190856 | ||
| Activation of eosinophils is more closely linked with interleukin-5 and nitric oxide production than tumor necrosis factor-α and immunoglobulin E levels | Q45810343 | ||
| Amelioration of murine dry eye disease by topical antagonist to chemokine receptor 2. | Q45930063 | ||
| Conjunctival T-cell subpopulations in Sjögren's and non-Sjögren's patients with dry eye. | Q45950875 | ||
| Immunological alterations in newly diagnosed primary Sjögren's syndrome characterized by skewed peripheral T-cell subsets and inflammatory cytokines | Q46605746 | ||
| Effective treatment with oral administration of rebamipide in a mouse model of Sjögren's syndrome | Q46778692 | ||
| Ex vivo CD(+) T-cell cytokine expression from patients with Sjögren's syndrome following in vitro stimulation to induce proliferation | Q46803675 | ||
| Multiple cytokine analysis in human tears: an optimized procedure for cytometric bead-based assay | Q47594873 | ||
| Destruction of salivary and lacrimal glands by Th1-polarized reaction in a model of secondary Sjögren's syndrome in lupus-prone female NZB × NZWF(1) mice. | Q51435076 | ||
| A dual role for interferon-gamma in the pathogenesis of Sjogren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse. | Q51821296 | ||
| Randomized, double-blind trial of anti-interferon-gamma antibodies in rheumatoid arthritis. | Q53992563 | ||
| Disruption of tight junction structure in salivary glands from Sjögren's syndrome patients is linked to proinflammatory cytokine exposure. | Q54443046 | ||
| Analysis of inflammatory cytokines in the tears of dry eye patients. | Q54467014 | ||
| Flow cytometric analysis of inflammatory markers in conjunctival epithelial cells of patients with dry eyes | Q57693415 | ||
| Expression of cell adhesion molecules in the salivary and lacrimal glands of Sjogren's syndrome | Q58205073 | ||
| Salivary cytokine profiles in primary Sjögren's syndrome differ from those in non-Sjögren sicca in terms of TNF-α levels and Th-1/Th-2 ratios | Q58336806 | ||
| Effects of Sequential Artificial Tear and Cyclosporine Emulsion Therapy on Conjunctival Goblet Cell Density and Transforming Growth Factor-β2 Production | Q61851319 | ||
| Dry Eye–Induced Conjunctival Epithelial Squamous Metaplasia Is Modulated by Interferon-γ | Q61851323 | ||
| Expression of Th-1 Chemokines and Chemokine Receptors on the Ocular Surface of C57BL/6 Mice: Effects of Desiccating Stress | Q61851325 | ||
| Desiccating Stress Induces T Cell-Mediated Sjogren's Syndrome-Like Lacrimal Keratoconjunctivitis | Q61851332 | ||
| Cytokine and chemokine levels in tears from healthy subjects | Q62075176 | ||
| Sjögren's syndrome: cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium | Q72120476 | ||
| Interferon-gamma and epithelial cell activation in Sjögren's syndrome | Q72186222 | ||
| A model to study viral and cytokine involvement in Sjögren's syndrome | Q72905646 | ||
| Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca | Q72993423 | ||
| Analysis of topical cyclosporine treatment of patients with dry eye syndrome: effect on conjunctival lymphocytes | Q73180482 | ||
| Interleukin-6 levels in the conjunctival epithelium of patients with dry eye disease treated with cyclosporine ophthalmic emulsion | Q74120740 | ||
| Altered frequency of type 1 cytokine secreting cells in the peripheral blood of patients with primary Sjögren's syndrome | Q74151277 | ||
| The Th1/Th2 cytokine balance changes with the progress of the immunopathological lesion of Sjogren's syndrome | Q74307371 | ||
| Analysis of the T-cell receptor Valpha repertoire and cytokine gene expression in Sjögren's syndrome | Q74502801 | ||
| Possible function of salivary gland epithelial cells as nonprofessional antigen-presenting cells in the development of Sjögren's syndrome | Q74793561 | ||
| T(H)1 cytokines are produced in labial salivary glands in Sjögren's syndrome, but also in healthy individuals | Q77402642 | ||
| Involvement of the interferon-gamma-induced T cell-attracting chemokines, interferon-gamma-inducible 10-kd protein (CXCL10) and monokine induced by interferon-gamma (CXCL9), in the salivary gland lesions of patients with Sjögren's syndrome | Q78387232 | ||
| Tear film osmolarity: determination of a referent for dry eye diagnosis | Q79143768 | ||
| Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity | Q79445121 | ||
| IL-13 receptors and signaling pathways: An evolving web | Q35110741 | ||
| Interferon-γ exacerbates dry eye-induced apoptosis in conjunctiva through dual apoptotic pathways. | Q35221255 | ||
| Desiccating stress induces CD4+ T-cell-mediated Sjögren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-γ | Q35235692 | ||
| A novel pro-lymphangiogenic function for Th17/IL-17. | Q35525349 | ||
| Transcriptome analysis of the interferon-signature defining the autoimmune process of Sjögren's syndrome | Q35535151 | ||
| Virus infection stages and distinct Th1 or Th17/Th22 T-cell responses in malaria/SHIV coinfection correlate with different outcomes of disease | Q35557138 | ||
| T lymphocyte subsets, cytokines, and effector functions | Q35563062 | ||
| Th2 cytokine genotypes are associated with a milder form of primary Sjogren's syndrome | Q35637117 | ||
| Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome | Q35674608 | ||
| Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease | Q35760634 | ||
| Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation | Q35865098 | ||
| Cytokines in tear fluid of patients with ocular graft-versus-host disease after allogeneic stem cell transplantation. | Q35883325 | ||
| The role of eye-associated lymphoid tissue in corneal immune protection | Q36055621 | ||
| PDE4 inhibition suppresses IL-17-associated immunity in dry eye disease | Q36122993 | ||
| Enforced IL-10 expression confers type 1 regulatory T cell (Tr1) phenotype and function to human CD4(+) T cells. | Q36220670 | ||
| Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. | Q36229199 | ||
| Tr1 cells: from discovery to their clinical application. | Q36390028 | ||
| Tear cytokine profiles in dysfunctional tear syndrome. | Q36637791 | ||
| IL-17 disrupts corneal barrier following desiccating stress. | Q36676135 | ||
| T(H)-17 cells in the circle of immunity and autoimmunity | Q36765453 | ||
| Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice. | Q36907644 | ||
| Cytokines and growth factors in airway remodeling in asthma. | Q36919505 | ||
| The CCR6/CCL20 axis mediates Th17 cell migration to the ocular surface in dry eye disease | Q36926074 | ||
| IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells | Q36985100 | ||
| Spdef null mice lack conjunctival goblet cells and provide a model of dry eye. | Q36986476 | ||
| Therapeutic efficacy of topical epigallocatechin gallate in murine dry eye. | Q36989668 | ||
| Th17 T cells: linking innate and adaptive immunity | Q37006577 | ||
| Th17 cells: a new fate for differentiating helper T cells | Q37049058 | ||
| Chronic dry eye disease is principally mediated by effector memory Th17 cells | Q37067291 | ||
| Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression | Q37071969 | ||
| Role of Th1 and Th17 cells in organ-specific autoimmunity. | Q37172965 | ||
| Sjögren's syndrome-like ocular surface disease in thrombospondin-1 deficient mice | Q37316518 | ||
| Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis | Q37316528 | ||
| Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans | Q37374938 | ||
| P921 | main subject | eye disease | Q3041498 |
| P304 | page(s) | 118-125 | |
| P577 | publication date | 2013-09-04 | |
| P1433 | published in | Experimental Eye Research | Q15754753 |
| P1476 | title | T helper cytokines in dry eye disease | |
| P478 | volume | 117 |
| Q100558870 | A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation |
| Q35773063 | Age-related Defects in Ocular and Nasal Mucosal Immune System and the Immunopathology of Dry Eye Disease |
| Q38886086 | Ageing and ocular surface immunity. |
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| Q34211406 | CCR7 is critical for the induction and maintenance of Th17 immunity in dry eye disease |
| Q35762942 | Changes of Ocular Surface and the Inflammatory Response in a Rabbit Model of Short-Term Exposure Keratopathy |
| Q39151688 | Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature |
| Q89689464 | Comparative lipidomic analysis of inflammatory mediators in the aqueous humor and tear fluid of humans and rabbits |
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| Q47625440 | Correlation of vitamin D levels with tear film stability and secretion in patients with dry eye syndrome. |
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| Q36038395 | Dual-Polymer Drops, Contact Lens Comfort, and Lid Wiper Epitheliopathy |
| Q89891558 | Efficacy and Safety of Lebrikizumab, a High-Affinity Interleukin 13 Inhibitor, in Adults With Moderate to Severe Atopic Dermatitis: A Phase 2b Randomized Clinical Trial |
| Q35507058 | Efficacy and safety of two new formulations of artificial tears in subjects with dry eye disease: a 3-month, multicenter, active-controlled, randomized trial |
| Q35532014 | Efficacy of 1% carboxymethylcellulose sodium for treating dry eye after phacoemulsification: results from a multicenter, open-label, randomized, controlled study |
| Q55363195 | Extended low oxygen transmissibility contact lens use induces alterations in the concentration of proinflammatory cytokines, enzymes and electrolytes in tear fluid. |
| Q33755012 | Goblet Cells Contribute to Ocular Surface Immune Tolerance-Implications for Dry Eye Disease. |
| Q50130535 | Goblet cell loss abrogates ocular surface immune tolerance. |
| Q38811416 | Goblet cells of the conjunctiva: A review of recent findings |
| Q89717876 | Gut dysbiosis is prevailing in Sjögren's syndrome and is related to dry eye severity |
| Q35831266 | IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells |
| Q36872927 | Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model. |
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| Q33870377 | Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation |
| Q38820726 | Langerhans cells prevent subbasal nerve damage and upregulate neurotrophic factors in dry eye disease |
| Q38663883 | MAPK signaling pathways in eye wounds: Multifunction and cooperation |
| Q53818675 | Management of post-LASIK dry eye: a multicenter randomized comparison of a new multi-ingredient artificial tear to carboxymethylcellulose. |
| Q35591394 | Mesenchymal stem/stromal cells protect the ocular surface by suppressing inflammation in an experimental dry eye. |
| Q52889830 | Randomized Controlled Crossover Trial Comparing the Impact of Sham or Intranasal Tear Neurostimulation on Conjunctival Goblet Cell Degranulation. |
| Q64066727 | Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice |
| Q47203561 | Serum components and clinical efficacies of autologous serum eye drops in dry eye patients with active and inactive Sjogren syndrome |
| Q41489266 | Sodium Hyaluronate in the Treatment of Dry Eye Syndrome: A Systematic Review and Meta-Analysis |
| Q47138569 | TRI Microspheres prevent key signs of dry eye disease in a murine, inflammatory model. |
| Q36039088 | The IMPACT study: a prospective evaluation of the effects of cyclosporine ophthalmic emulsion 0.05% on ocular surface staining and visual performance in patients with dry eye |
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