Effect of wild-type Shigella species and attenuated Shigella vaccine candidates on small intestinal barrier function, antigen trafficking, and cytokine release

scientific article published on 09 January 2014

Effect of wild-type Shigella species and attenuated Shigella vaccine candidates on small intestinal barrier function, antigen trafficking, and cytokine release is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2014PLoSO...985211F
P356DOI10.1371/JOURNAL.PONE.0085211
P932PMC publication ID3887025
P698PubMed publication ID24416363
P5875ResearchGate publication ID259701638

P50authorAlessio FasanoQ18686101
Myron M. LevineQ29564379
Maria R FiorentinoQ42768381
P2093author name stringMarcelo B Sztein
P2860cites workPKC eta regulates occludin phosphorylation and epithelial tight junction integrityQ24311692
Shigella flexneri type III secretion system effectors OspB and OspF target the nucleus to downregulate the host inflammatory response via interactions with retinoblastoma proteinQ24315859
Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral poleQ24646749
Identification and Analysis of Occludin Phosphosites: A Combined Mass Spectrometry and Bioinformatics ApproachQ27653352
Possible involvement of phosphorylation of occludin in tight junction formationQ41104367
The enterocyte-like differentiation of the Caco-2 tumor cell line strongly correlates with responsiveness to cAMP and activation of kinase A pathway.Q41446001
CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity.Q41506361
Pathophysiology of Shigella diarrhea in the rhesus monkey: intestinal transport, morphological, and bacteriological studiesQ44633325
Occludin phosphorylation in regulation of epithelial tight junctions.Q45963248
Pathogenesis of Shigella dysenteriae 1 (Shiga) DysenteryQ46613719
Inoculum size in shigellosis and implications for expected mode of transmissionQ47172816
Prevalence of the sat, set and sen genes among diverse serotypes of Shigella flexneri strains isolated from patients with acute diarrhoeaQ47361536
Prevalence of the genes for shigella enterotoxins 1 and 2 among clinical isolates of shigella in Israel.Q48294010
Effects of diarrhea associated with specific enteropathogens on the growth of children in rural BangladeshQ50584891
Shigella flexneri regulates tight junction-associated proteins in human intestinal epithelial cells.Q51191281
New animal model of shigellosis in the Guinea pig: its usefulness for protective efficacy studies.Q53579124
A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: clinical experience and implications for Shigella infectivity.Q54158784
Prevalence of Shigella Enterotoxin 1 among Shigella Clinical Isolates of Diverse SerotypesQ54601009
Construction of an auxotrophic Shigella flexneri strain for use as a live vaccine.Q54712481
Etiology of Diarrhea Among Travelers and Foreign Residents in NepalQ54742261
Laboratory-confirmed shigellosis in the United States, 1989-2002: epidemiologic trends and patternsQ64133569
The pathology of Shigella flexneri infection in rhesus monkeys: an endoscopic and histopathological study of colonic lesionsQ68517654
Local and systemic antibody responses to Shigella infection in rhesus monkeysQ68944588
Immunity in Shigellosis. II. Protection Induced by Oral Live Vaccine or Primary InfectionQ69156182
Safety and immunogenicity of CVD 1208S, a live, oral DeltaguaBA Deltasen Deltaset Shigella flexneri 2a vaccine grown on animal-free mediaQ81445405
Enteric glia protect against Shigella flexneri invasion in intestinal epithelial cells: a role for S-nitrosoglutathioneQ82788556
Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colonQ33416439
Effect of shigella enterotoxin 1 (ShET1) on rabbit intestine in vitro and in vivoQ33617990
A challenge model for Shigella dysenteriae 1 in cynomolgus monkeys (Macaca fascicularis).Q33676706
A piglet model of acute gastroenteritis induced by Shigella dysenteriae Type 1Q33678906
Global burden of Shigella infections: implications for vaccine development and implementation of control strategiesQ33749510
A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasionQ34192675
Shigella enterotoxin 1: an enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitroQ34224319
Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivoQ34482917
Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeabilityQ34561438
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier functionQ34918139
Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cellsQ35003095
Identification and cloning of a novel plasmid-encoded enterotoxin of enteroinvasive Escherichia coli and Shigella strainsQ35455031
Live attenuated Shigella dysenteriae type 1 vaccine strains overexpressing shiga toxin B subunitQ35598035
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane proteinQ36237286
Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosisQ36363758
In vitro Intestinal Mucosal Epithelial Responses to Wild-Type Salmonella Typhi and Attenuated Typhoid VaccinesQ36601934
Occludin is a functional component of the tight junction.Q36828867
Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard roadQ36844719
Movement along actin filaments of the perijunctional area and de novo polymerization of cellular actin are required for Shigella flexneri colonization of epithelial Caco-2 cell monolayersQ36956026
Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella sppQ37010733
Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeabilityQ37344103
Modulation of tight junction structure and function by kinases and phosphatases targeting occludinQ37982360
The Shigella human challenge modelQ38035961
Protein phosphatases 2A and 1 interact with occludin and negatively regulate the assembly of tight junctions in the CACO-2 cell monolayerQ38304743
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208.Q39146446
Development of an auxotrophic oral live Shigella flexneri vaccineQ39227963
Prevalence of Shigella enterotoxins 1 and 2 among Shigella strains isolated from patients with traveler's diarrheaQ39453145
Shigella infection in a SCID mouse-human intestinal xenograft model: role for neutrophils in containing bacterial dissemination in human intestineQ39519990
Intracellular multiplication and virulence of Shigella flexneri auxotrophic mutants.Q39569905
Shigella enterotoxin-2 is a type III effector that participates in Shigella-induced interleukin 8 secretion by epithelial cellsQ39610195
Construction, characterization, and animal testing of WRSd1, a Shigella dysenteriae 1 vaccineQ39655324
Etiology and epidemiology of travelers' diarrhea in AsiaQ39737855
Effects of enteropathogenic bacteria & lactobacilli on chemokine secretion & Toll like receptor gene expression in two human colonic epithelial cell lines.Q39792532
Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosisQ40211202
Experimental Shigella infections: characteristics of a fatal infection produced in guinea pigs.Q40314454
Evaluation of the safety, immunogenicity, and efficacy in healthy adults of four doses of live oral hybrid Escherichia coli-Shigella flexneri 2a vaccine strain EcSf2a-2Q40687041
Phosphorylation of occludin correlates with occludin localization and function at the tight junctionQ41070997
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectattenuated vaccineQ1810913
P304page(s)e85211
P577publication date2014-01-09
P1433published inPLOS OneQ564954
P1476titleEffect of wild-type Shigella species and attenuated Shigella vaccine candidates on small intestinal barrier function, antigen trafficking, and cytokine release
P478volume9

Reverse relations

cites work (P2860)
Q30252849Analysis of Shigella flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts.
Q38776163Characterization of a multicomponent live, attenuated Shigella flexneri vaccine
Q49997335Cryptosporidium parvum disrupts intestinal epithelial barrier function via altering expression of key tight junction and adherens junction proteins
Q55167657Cytokine Tuning of Intestinal Epithelial Function.
Q37497781Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit
Q52691745Modulation of Intestinal Paracellular Transport by Bacterial Pathogens.
Q58327078Prolamins of maize and wheat differentially affect intestinal cells both in biopsies of celiac patients and CACO-2 cell line
Q39172391Reconstituted human polyclonal plasma-derived secretory-like IgM and IgA maintain the barrier function of epithelial cells infected with an enteropathogen
Q38760352Toxoplasma gondii Infection Promotes Epithelial Barrier Dysfunction of Caco-2 Cells.

Search more.