| scholarly article | Q13442814 |
| P356 | DOI | 10.3109/07388551.2010.525498 |
| P698 | PubMed publication ID | 21091161 |
| P50 | author | Rajan Vyas | Q37830933 |
| Rupinder Tewari | Q40274249 | ||
| P2093 | author name string | Ankur Gautam | |
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| Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis | Q27644008 | ||
| Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis | Q27644055 | ||
| Structure of theE. colibifunctional GlmU acetyltransferase active site with substrates and products | Q27644659 | ||
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| Identification of dynamic structural motifs involved in peptidoglycan glycosyltransfer | Q27651887 | ||
| Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme | Q27652893 | ||
| PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity | Q27653322 | ||
| Structure ofN-acetylglucosamine-1-phosphate uridyltransferase (GlmU) fromMycobacterium tuberculosisin a cubic space group | Q27655339 | ||
| Characterization of the active site of S. aureus monofunctional glycosyltransferase (Mtg) by site-directed mutation and structural analysis of the protein complexed with moenomycin | Q27655367 | ||
| Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli | Q27655550 | ||
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| (E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) | Q27732705 | ||
| The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls | Q27733360 | ||
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| Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin | Q27733409 | ||
| Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin | Q27734363 | ||
| X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution | Q27734743 | ||
| Involvement of the C terminus in intramolecular nitrogen channeling in glucosamine 6-phosphate synthase: evidence from a 1.6 A crystal structure of the isomerase domain | Q27765339 | ||
| The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism. | Q27936943 | ||
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| An evolving hierarchical family classification for glycosyltransferases | Q28190475 | ||
| Recent advances in the formation of the bacterial peptidoglycan monomer unit | Q28204307 | ||
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| On the Initial Stage in Peptidoglycan Synthesis. Phospho-N-acetylmuramyl-pentapeptide Translocase (Uridine Monophosphate)* | Q28257596 | ||
| Initial membrane reaction in peptidoglycan synthesis. Interaction of lipid with phospho-N-acetylmuramylpentapeptide translocase | Q28326814 | ||
| On the specificity of the uridine diphospho-N-acetylmuramyl-alanyl-D-glutamic acid: diamino acid ligase of Bifidobacterium globosum | Q28333474 | ||
| Comparison of the UDP-N-acetylmuramate:L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae | Q28487429 | ||
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| 5-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases | Q58216000 | ||
| Three-dimensional structure of adenyl kinase | Q59077251 | ||
| MurAA, catalysing the first committed step in peptidoglycan biosynthesis, is a target of Clp-dependent proteolysis in Bacillus subtilis | Q28488903 | ||
| Identification of the Pseudomonas aeruginosa glmM gene, encoding phosphoglucosamine mutase | Q28492574 | ||
| Peptidoglycan structure and architecture | Q29617858 | ||
| Antibacterial resistance worldwide: causes, challenges and responses | Q29620008 | ||
| Recent developments in structure-based drug design | Q30652842 | ||
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| Identification of novel inhibitors of Pseudomonas aeruginosa MurC enzyme derived from phage-displayed peptide libraries | Q30890784 | ||
| Identification and characterization of new inhibitors of the Escherichia coli MurA enzyme | Q31016009 | ||
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| Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen | Q33225062 | ||
| Selection of peptide inhibitors against the Pseudomonas aeruginosa MurD cell wall enzyme | Q33235482 | ||
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| A MurF inhibitor that disrupts cell wall biosynthesis in Escherichia coli | Q33301093 | ||
| Two active forms of UDP-N-acetylglucosamine enolpyruvyl transferase in gram-positive bacteria | Q33601835 | ||
| Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. | Q33714592 | ||
| Mycobacterial lipid II is composed of a complex mixture of modified muramyl and peptide moieties linked to decaprenyl phosphate | Q33726863 | ||
| Active site restructuring regulates ligand recognition in class A penicillin-binding proteins | Q33756467 | ||
| Reaction mechanism of phosphoglucosamine mutase from Escherichia coli. | Q33860899 | ||
| Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli | Q33886827 | ||
| Beta-lactam antibiotics: from antibiosis to resistance and bacteriology | Q33951933 | ||
| Active site comparisons highlight structural similarities between myosin and other P-loop proteins | Q34017547 | ||
| Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae | Q34113767 | ||
| Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae | Q34140737 | ||
| Penicillin-binding proteins 1a and 1b form independent dimers in Escherichia coli. | Q34313500 | ||
| 3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria | Q34352165 | ||
| Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli | Q34370285 | ||
| The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity | Q34510574 | ||
| Peptidoglycan synthesis in the absence of class A penicillin-binding proteins in Bacillus subtilis | Q34514614 | ||
| In vitro and in vivo functional activity of Chlamydia MurA, a UDP-N-acetylglucosamine enolpyruvyl transferase involved in peptidoglycan synthesis and fosfomycin resistance | Q34514901 | ||
| Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance | Q34541598 | ||
| The mechanism of action of ramoplanin and enduracidin | Q34553065 | ||
| Structure, function and dynamics in the mur family of bacterial cell wall ligases | Q34560768 | ||
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| Mannopeptimycins, new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98: antibacterial and mechanistic activities. | Q34722061 | ||
| Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA. | Q34968575 | ||
| Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate | Q35021822 | ||
| Structure and function of the Mur enzymes: development of novel inhibitors | Q35030909 | ||
| Mechanism of action of oritavancin and related glycopeptide antibiotics | Q35066202 | ||
| Novel inhibitors of bacterial cell wall synthesis. | Q35565580 | ||
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| A promoter for the first nine genes of the Escherichia coli mra cluster of cell division and cell envelope biosynthesis genes, including ftsI and ftsW. | Q35630514 | ||
| Oritavancin and tigecycline: investigational antimicrobials for multidrug-resistant bacteria | Q35637071 | ||
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| The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm | Q36087726 | ||
| Replacement of diaminopimelic acid by cystathionine or lanthionine in the peptidoglycan of Escherichia coli | Q36109102 | ||
| Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli. | Q36122633 | ||
| The Escherichia coli mraY gene encoding UDP-N-acetylmuramoyl-pentapeptide: undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide transferase | Q36129411 | ||
| The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis | Q36150070 | ||
| Incorporation of LL-diaminopimelic acid into peptidoglycan of Escherichia coli mutants lacking diaminopimelate epimerase encoded by dapF. | Q36202185 | ||
| Does the cell wall of bacteria remain a viable source of targets for novel antibiotics? | Q36313793 | ||
| Lipid intermediates in the biosynthesis of bacterial peptidoglycan | Q36314747 | ||
| MraY Inhibitors as Novel Antibacterial Agents | Q36321142 | ||
| Syntheses around the transglycosylation step in peptidoglycan biosynthesis | Q36340522 | ||
| Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine | Q36379261 | ||
| The monofunctional glycosyltransferase of Escherichia coli localizes to the cell division site and interacts with penicillin-binding protein 3, FtsW, and FtsN. | Q36483203 | ||
| Fluorescence detection-based functional assay for high-throughput screening for MraY. | Q36492019 | ||
| Penicillin binding proteins: key players in bacterial cell cycle and drug resistance processes. | Q36566587 | ||
| Telavancin: a novel lipoglycopeptide for serious gram-positive infections | Q36736356 | ||
| DNA sequence of the murE-murD region of Bacillus subtilis 168. | Q36777227 | ||
| Serine beta-lactamases and penicillin-binding proteins | Q36784607 | ||
| Three-dimensional structure of moenomycin A--a potent inhibitor of penicillin-binding protein 1b. | Q36896175 | ||
| Development of novel inhibitors targeting intracellular steps of peptidoglycan biosynthesis | Q36907456 | ||
| The biosynthesis of peptidoglycan lipid-linked intermediates | Q37032866 | ||
| Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity | Q37051672 | ||
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| Structural details of the glycosyltransferase step of peptidoglycan assembly. | Q37250015 | ||
| Structure-based drug design strategies in medicinal chemistry | Q37597256 | ||
| Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release | Q37866109 | ||
| Identification of the gonococcal glmU gene encoding the enzyme N-acetylglucosamine 1-phosphate uridyltransferase involved in the synthesis of UDP-GlcNAc | Q38288653 | ||
| Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments | Q38294460 | ||
| Characterization of the bifunctional glycosyltransferase/acyltransferase penicillin-binding protein 4 of Listeria monocytogenes | Q38315739 | ||
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| Functional characterization of penicillin-binding protein 1b from Streptococcus pneumoniae | Q38357557 | ||
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| Development of a whole-cell assay for peptidoglycan biosynthesis inhibitors | Q39651496 | ||
| The glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae catalyzes the polymerization of murein glycan chains | Q39791499 | ||
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| A putative monofunctional glycosyltransferase is expressed in Ralstonia eutropha | Q39846218 | ||
| Identification and characterization of cell wall-cell division gene clusters in pathogenic gram-positive cocci | Q39847107 | ||
| Identification of tms-26 as an allele of the gcaD gene, which encodes N-acetylglucosamine 1-phosphate uridyltransferase in Bacillus subtilis | Q39939478 | ||
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| Mechanism of action of the mannopeptimycins, a novel class of glycopeptide antibiotics active against vancomycin-resistant gram-positive bacteria | Q40622160 | ||
| Phospho-N-acetyl-muramyl-pentapeptide translocase from Escherichia coli: catalytic role of conserved aspartic acid residues | Q40634273 | ||
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| Differential antibacterial activity of moenomycin analogues on gram-positive bacteria | Q42636554 | ||
| A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA). | Q42647502 | ||
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| Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA). | Q42680309 | ||
| Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate:L-alanine ligase | Q42845111 | ||
| Binding of substrates and modifiers to glucosamine synthetase | Q42922023 | ||
| Characterization of L-glutamine:D-fructose-6-phosphate amidotransferase from an extreme thermophile Thermus thermophilus HB8. | Q43024394 | ||
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| Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF. | Q43266886 | ||
| Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1-phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activi | Q43510086 | ||
| Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae | Q43591572 | ||
| Inhibitors of the bacterial cell wall biosynthesis enzyme MurC. | Q43621566 | ||
| Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis | Q43835367 | ||
| Benzylidene rhodanines as novel inhibitors of UDP-N-acetylmuramate/L-alanine ligase | Q43886263 | ||
| The Specificity of Enzymes Adding Amino Acids in the Synthesis of the Peptidoglycan Precursors of Corynebacterium poinsettiae and Corynebacterium insidiosum | Q43934957 | ||
| The first total synthesis of lipid II: the final monomeric intermediate in bacterial cell wall biosynthesis | Q43944569 | ||
| Intrinsic lipid preferences and kinetic mechanism of Escherichia coli MurG. | Q44001893 | ||
| Mannopeptimycins, novel antibacterial glycopeptides from Streptomyces hygroscopicus, LL-AC98. | Q44099734 | ||
| A kinetic characterization of the glycosyltransferase activity of Eschericia coli PBP1b and development of a continuous fluorescence assay | Q44171772 | ||
| A MurG assay which utilises a synthetic analogue of lipid I. | Q44320619 | ||
| Discovery of the first antibacterial small molecule inhibitors of MurB. | Q44345485 | ||
| Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes | Q44381515 | ||
| 2-Phenyl-5,6-dihydro-2H-thieno[3,2-c]pyrazol-3-ol derivatives as new inhibitors of bacterial cell wall biosynthesis | Q44508067 | ||
| Ramoplanin inhibits bacterial transglycosylases by binding as a dimer to lipid II. | Q44514000 | ||
| Structures of K(0.05)Na(0.95)NbO3 (50-300 K) and K(0.30)Na(0.70)NbO3 (100-200 K). | Q44948788 | ||
| Assembly and stability of nisin-lipid II pores | Q45045783 | ||
| Antimicrobial activity of dalbavancin tested against Gram-positive clinical isolates from Latin American medical centres | Q45243569 | ||
| Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution | Q46128390 | ||
| 4-Alkyl and 4,4'-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis | Q46465514 | ||
| Antibiotic resistance-the problem intensifies | Q46540143 | ||
| Design and synthesis of novel N-benzylidenesulfonohydrazide inhibitors of MurC and MurD as potential antibacterial agents. | Q46765233 | ||
| Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae | Q46826792 | ||
| Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction | Q46835683 | ||
| Glutamine binding opens the ammonia channel and activates glucosamine-6P synthase | Q46844173 | ||
| Staphylococcus aureus MurC participates in L-alanine recognition via histidine 343, a conserved motif in the shallow hydrophobic pocket | Q46847275 | ||
| Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening | Q47443022 | ||
| Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosis | Q47904411 | ||
| Cloning and sequencing of Staphylococcus aureus murC, a gene essential for cell wall biosynthesis | Q47909491 | ||
| Assembly of the monomer unit of bacterial peptidoglycan | Q48007374 | ||
| Conditionally lethal Escherichia coli murein mutants contain point defects that map to regions conserved among murein and folyl poly-gamma-glutamate ligases: identification of a ligase superfamily | Q48049705 | ||
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| The cell wall and cell division gene cluster in the Mra operon of Pseudomonas aeruginosa: cloning, production, and purification of active enzymes | Q48372742 | ||
| Better substrates for bacterial transglycosylases | Q49315804 | ||
| Glucosamine synthetase from Escherichia coli: kinetic mechanism and inhibition by N3-fumaroyl-L-2,3-diaminopropionic derivatives | Q50198102 | ||
| Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening. | Q51816512 | ||
| Evaluation of the kinetic mechanism of Escherichia coli uridine diphosphate-N-acetylmuramate:L-alanine ligase. | Q52262082 | ||
| Steady-state kinetic mechanism of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase. | Q52344239 | ||
| 2-Aminotetralones: novel inhibitors of MurA and MurZ. | Q52852098 | ||
| Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus. | Q53584302 | ||
| Structure-based optimization of MurF inhibitors. | Q53603346 | ||
| Structure-activity relationships of novel potent MurF inhibitors. | Q53645851 | ||
| Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria. | Q53756233 | ||
| Topological analysis of the MraY protein catalysing the first membrane step of peptidoglycan synthesis. | Q54072596 | ||
| Glucosamine-6-phosphate synthase from Escherichia coli: determination of the mechanism of inactivation by N3-fumaroyl-L-2,3-diaminopropionic derivatives. | Q54325994 | ||
| Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases. | Q54419171 | ||
| Fluorescent reagents for in vitro studies of lipid-linked steps of bacterial peptidoglycan biosynthesis: derivatives of UDPMurNAc-pentapeptide containing d-cysteine at position 4 or 5. | Q54448724 | ||
| Pyrazolidine-3,5-diones and 5-hydroxy-1H-pyrazol-3(2H)-ones, inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase. | Q54454869 | ||
| Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA. | Q54456599 | ||
| Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD. | Q54475713 | ||
| In vitro murein peptidoglycan synthesis by dimers of the bifunctional transglycosylase-transpeptidase PBP1B from Escherichia coli. | Q54479227 | ||
| Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention. | Q54528035 | ||
| Affinity labeling of Escherichia coli glucosamine-6-phosphate synthase with a fructose 6-phosphate analog--evidence for proximity between the N-terminal cysteine and the fructose-6-phosphate-binding site. | Q54567628 | ||
| Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin. | Q54590227 | ||
| Study of the overproduced uridine-diphosphate-N-acetylmuramate:L-alanine ligase from Escherichia coli. | Q54590638 | ||
| Structural studies of Escherichia coli UDP-N-acetylmuramate:L-alanine ligase. | Q54593807 | ||
| Biochemical evidence for the formation of a covalent acyl-phosphate linkage between UDP-N-acetylmuramate and ATP in the Escherichia coli UDP-N-acetylmuramate:L-alanine ligase-catalyzed reaction. | Q54593810 | ||
| The mode of action of bacilysin and anticapsin and biochemical properties of bacilysin-resistant mutants | Q54613752 | ||
| Possible involvement of Lys603 from Escherichia coli glucosamine-6-phosphate synthase in the binding of its substrate fructose 6-phosphate. | Q54690765 | ||
| Over-production, purification and properties of the uridine-diphosphate-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate ligase from Escherichia coli. | Q54704735 | ||
| Partial purification and specificity studies of the D-glutamate-adding and D-alanyl-D-alanine-adding enzymes from Escherichia coli K12. | Q54762576 | ||
| Glucosamine synthetase from Escherichia coli: purification, properties, and glutamine-utilizing site location. | Q54765865 | ||
| Specificity of the uridine-diphosphate-N-acetylmuramyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate synthetase from Escherichia coli. | Q54790491 | ||
| Thermotoga maritima sp. nov. represents a new genus of unique extremely thermophilic eubacteria growing up to 90°C | Q56701239 | ||
| Crystallization and Preliminary X-ray Analysis of the Two Domains of Glucosamine-6-phosphate Synthase from Escherichia coli | Q57276497 | ||
| Lysine 22 in UDP-N-Acetylglucosamine Enolpyruvyl Transferase fromEnterobacter cloacaeIs Crucial for Enzymatic Activity and the Formation of Covalent Adducts with the Substrate Phosphoenolpyruvate and the Antibiotic Fosfomycin† | Q57978316 | ||
| Role of the Ortholog and Paralog Amino Acid Invariants in the Active Site of the UDP-MurNAc-l-alanine:d-glutamate Ligase (MurD)† | Q57998973 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 295-336 | |
| P577 | publication date | 2010-11-22 | |
| P1433 | published in | Critical Reviews in Biotechnology | Q5186663 |
| P1476 | title | Peptidoglycan biosynthesis machinery: a rich source of drug targets | |
| P478 | volume | 31 |
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