| scholarly article | Q13442814 |
| P50 | author | Divya Vohora | Q43145694 |
| Razia Khanam | Q82418116 | ||
| P2093 | author name string | M Bhowmik | |
| P2860 | cites work | Cloning and functional expression of the human histamine H3 receptor | Q22009916 |
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| Histamine and its receptors | Q24670415 | ||
| p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils | Q28141837 | ||
| Modulation of neurotransmitter release via histamine H3 heteroreceptors | Q28244199 | ||
| International Union of Pharmacology. XIII. Classification of histamine receptors | Q28249809 | ||
| Histamine in the brain: beyond sleep and memory | Q28284471 | ||
| The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons | Q28292338 | ||
| Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB | Q28505126 | ||
| Akt1 regulates a JNK scaffold during excitotoxic apoptosis | Q28574706 | ||
| Differences in activation of ERK1/2 and p38 kinase in Jnk3 null mice following KA treatment. | Q43037982 | ||
| Involvement of histamine 1 receptor in seizure susceptibility and neuroprotection in immature mice. | Q43111831 | ||
| Proconvulsant potential of cyproheptadine in experimental animal models. | Q43225308 | ||
| Different role of cAMP dependent protein kinase and CaMKII in H3 receptor regulation of histamine synthesis and release. | Q43279952 | ||
| Identification of rat H3 receptor isoforms with different brain expression and signaling properties. | Q43513207 | ||
| Mechanism responsible for epileptogenic activity by first-generation H1-antagonists in rats | Q43514287 | ||
| Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain | Q43690545 | ||
| Identification and characterization of histamine H4 receptor | Q43702138 | ||
| Histamine and selective H3-receptor ligands: a possible role in the mechanism and management of epilepsy | Q43722658 | ||
| Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists | Q43803802 | ||
| Presynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway. | Q43830258 | ||
| Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats. | Q43946398 | ||
| Histamine levels and clonic convulsions of electrically-induced seizure in mice: the effects of alpha-fluoromethylhistidine and metoprine. | Q44008589 | ||
| Cell signaling in the epileptic hippocampus | Q44012484 | ||
| The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. | Q44046080 | ||
| Effects of MK-801 and CNQX on various neurotoxic responses induced by kainic acid in mice. | Q44274104 | ||
| Down-regulation of delta-opioid receptors in Na+/H+ exchanger 1 null mutant mouse brain with epilepsy. | Q44351035 | ||
| Chemical kindling induced by pentylenetetrazol in histamine H(1) receptor gene knockout mice (H(1)KO), histidine decarboxylase-deficient mice (HDC(-/-)) and mast cell-deficient W/W(v) mice. | Q44366949 | ||
| Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats. | Q44529329 | ||
| Contribution of the histaminergic receptor subtypes to histamine-induced cerebellar granular neurotoxicity | Q44594190 | ||
| Improvement in fear memory by histamine-elicited ERK2 activation in hippocampal CA3 cells. | Q44610916 | ||
| Effects of clobenpropit on pentylenetetrazole-kindled seizures in rats | Q44683125 | ||
| Development of amygdaloid kindling in histidine decarboxylase-deficient and histamine H1 receptor-deficient mice | Q44805056 | ||
| Akt activity in Alzheimer's disease and other neurodegenerative disorders | Q44838986 | ||
| 4-Aminopyridine-induced epileptogenesis depends on activation of mitogen-activated protein kinase ERK. | Q44846033 | ||
| Inhibitory effect of iodophenpropit, a selective histamine H3 antagonist, on amygdaloid kindled seizures | Q44886274 | ||
| Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion | Q44910869 | ||
| Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. | Q41086785 | ||
| The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS | Q41420104 | ||
| Is histamine an anticonvulsive inhibitory transmitter? | Q42059596 | ||
| CREB activity maintains the survival of cingulate cortical pyramidal neurons in the adult mouse brain | Q42089518 | ||
| Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors. | Q42164100 | ||
| Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice | Q42282710 | ||
| Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography | Q42284492 | ||
| H3 receptor antagonism enhances NCAM PSA-mediated plasticity and improves memory consolidation in odor discrimination and delayed match-to-position paradigms | Q42458022 | ||
| A histamine-containing neuronal system in human brain | Q42484231 | ||
| The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo. | Q42488934 | ||
| Endogenous GABA modulates histamine release from the anterior hypothalamus of the rat. | Q42518998 | ||
| Therapeutic doses of theophylline exert proconvulsant effects in developing mice | Q42547038 | ||
| Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice. | Q42749349 | ||
| Glutamate and GABA in the balance: convergent pathways sustain seizures during status epilepticus | Q42974956 | ||
| Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133 | Q29617856 | ||
| Function and regulation of CREB family transcription factors in the nervous system | Q29619559 | ||
| ERK activation causes epilepsy by stimulating NMDA receptor activity | Q30480774 | ||
| Decreased CREB levels suppress epilepsy | Q30577603 | ||
| The physiology of brain histamine. | Q31875011 | ||
| Carnosine protects against NMDA-induced neurotoxicity in differentiated rat PC12 cells through carnosine-histidine-histamine pathway and H(1)/H(3) receptors | Q33266625 | ||
| Status epilepticus and wide-complex tachycardia secondary to diphenhydramine overdose | Q33881137 | ||
| The CREB/CRE transcriptional pathway: protection against oxidative stress-mediated neuronal cell death | Q33908467 | ||
| High constitutive activity of native H3 receptors regulates histamine neurons in brain. | Q33929208 | ||
| ERK/MAPK is essential for endogenous neuroprotection in SCN2.2 cells | Q33999730 | ||
| Involvement of central histamine in amygdaloid kindled seizures in rats | Q34097939 | ||
| Hsp70 and its molecular role in nervous system diseases | Q34170760 | ||
| Excitotoxic cell death | Q34245367 | ||
| Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor | Q34249836 | ||
| The histamine H3 receptor: from gene cloning to H3 receptor drugs | Q34387276 | ||
| Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research | Q34458158 | ||
| Antiepileptic drugs and neuroprotection: current status and future roles | Q34461434 | ||
| Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat. | Q34470541 | ||
| Coupling of histamine H3 receptors to neuronal Na+/H+ exchange: a novel protective mechanism in myocardial ischemia | Q34500237 | ||
| Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway. | Q34537179 | ||
| Glycogen synthase kinase 3: an emerging therapeutic target | Q34552674 | ||
| The physiological and pathophysiological roles of neuronal histamine: an insight from human positron emission tomography studies | Q34554604 | ||
| Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway | Q34568648 | ||
| The histamine H3 receptor: from discovery to clinical trials with pitolisant | Q34629532 | ||
| Constitutive activity of the histamine H3 receptor. | Q34638124 | ||
| Histamine in the nervous system | Q34795903 | ||
| The histamine H3 receptor as a therapeutic drug target for CNS disorders | Q34980219 | ||
| Pharmacological effects of carcinine on histaminergic neurons in the brain | Q35047783 | ||
| Histamine H3 receptor: a potential drug target for the treatment of central nervous system disorders | Q35551812 | ||
| Genetic and pharmacological aspects of histamine H3 receptor heterogeneity | Q35556324 | ||
| Histamine 3 receptor activation reduces the expression of neuronal angiotensin II type 1 receptors in the heart | Q35650739 | ||
| Neuroprotection abilities of cytosolic phospholipase A2 inhibitors in kainic acid-induced neurodegeneration | Q35731291 | ||
| Mitogen-activated protein kinases in apoptosis regulation | Q35743118 | ||
| Advances in protein kinase B signalling: AKTion on multiple fronts | Q35766370 | ||
| CRE-mediated transcription and COX-2 expression in the pilocarpine model of status epilepticus | Q35858127 | ||
| [Molecular imaging of histamine receptors in the human brain]. | Q51976825 | ||
| AQ-0145, a newly developed histamine H3 antagonist, decreased seizure susceptibility of electrically induced convulsions in mice. | Q52012433 | ||
| In-vivo histamine H3 receptor antagonism activates cellular signaling suggestive of symptomatic and disease modifying efficacy in Alzheimer's disease | Q53418054 | ||
| Inhibition of sound-induced convulsions by metoprine in the audiogenic seizure susceptible rat | Q70185256 | ||
| Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decarboxylase as a marker | Q71321202 | ||
| Thioperamide, a selective histamine H3 receptor antagonist, protects against PTZ-induced seizures in mice | Q73840323 | ||
| Lack of substantial effect of the H(3)-antagonist thioperamide and of the non-selective mixed H(3)-antagonist/H(1)-agonist betahistine on amygdaloid kindled seizures | Q73915440 | ||
| Effect of clobenpropit, a centrally acting histamine H3-receptor antagonist, on electroshock- and pentylenetetrazol-induced seizures in mice | Q77591881 | ||
| Cerebral ischemia and brain histamine | Q81255574 | ||
| Seizure-modifying potential of histamine H1 antagonists: a clinical observation | Q83284712 | ||
| Progress on the issue of excitotoxic injury modification vs. real neuroprotection; implications for post-traumatic epilepsy | Q84758681 | ||
| ??? | Q28299003 | ||
| Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability | Q35868150 | ||
| Mammalian histidine decarboxylase: from structure to function | Q35990462 | ||
| Histamine-containing neurons in the rat hypothalamus | Q36258236 | ||
| The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials | Q36265307 | ||
| Histaminergic neurons in the rat brain: correlative immunocytochemistry, Golgi impregnation, and electron microscopy | Q36425925 | ||
| Modulation of histamine synthesis and release in brain via presynaptic autoreceptors and heteroreceptors | Q36601233 | ||
| Molecular aspects of the histamine H3 receptor | Q36727499 | ||
| Progress in neuroprotective strategies for preventing epilepsy. | Q36739694 | ||
| Regulation of pH in the mammalian central nervous system under normal and pathological conditions: facts and hypotheses. | Q37025232 | ||
| Neuroprotection in epilepsy | Q37106016 | ||
| Seizures and sodium hydrogen exchangers: potential of sodium hydrogen exchanger inhibitors as novel anticonvulsants. | Q37320352 | ||
| Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: role of GSK-3beta in adult brain | Q37380476 | ||
| Alteration of epileptogenesis genes | Q37426983 | ||
| Emerging concepts in the pathogenesis of epilepsy and epileptogenesis | Q37443484 | ||
| Molecular and biochemical pharmacology of the histamine H4 receptor | Q37469102 | ||
| Inducible cAMP early repressor (ICER) and brain functions | Q37478244 | ||
| Histamine H3 and H4 receptors as novel drug targets. | Q37598261 | ||
| ERK and cell death: ERK1/2 in neuronal death | Q37618294 | ||
| Phospholipases A2 and inflammatory responses in the central nervous system | Q37621283 | ||
| Therapeutic approaches to epileptogenesis--hope on the horizon | Q37771378 | ||
| CREB: a multifaceted regulator of neuronal plasticity and protection | Q37806285 | ||
| Histamine receptors in the CNS as targets for therapeutic intervention. | Q37842889 | ||
| En route to new blockbuster anti-histamines: surveying the offspring of the expanding histamine receptor family | Q37854214 | ||
| Histamine in neurotransmission and brain diseases. | Q37880826 | ||
| Several down, a few to go: histamine H3 receptor ligands making the final push towards the market? | Q37944920 | ||
| Classical neurotransmitters and neuropeptides involved in generalized epilepsy: a focus on antiepileptic drugs | Q37952355 | ||
| Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control | Q37988223 | ||
| Discovery of naturally occurring splice variants of the rat histamine H3 receptor that act as dominant-negative isoforms | Q38316776 | ||
| A common pattern of persistent gene activation in human neocortical epileptic foci | Q38319641 | ||
| A detailed mapping of the histamine H(3) receptor and its gene transcripts in rat brain | Q38363392 | ||
| Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models | Q39924456 | ||
| The Akt/GSK-3beta axis as a new signaling pathway of the histamine H(3) receptor. | Q40108899 | ||
| Carnosine inhibits pentylenetetrazol-induced seizures by histaminergic mechanisms in histidine decarboxylase knock-out mice. | Q40232552 | ||
| Opposing roles for ERK1/2 in neuronal oxidative toxicity: distinct mechanisms of ERK1/2 action at early versus late phases of oxidative stress | Q40290776 | ||
| Seizure susceptibility due to antihistamines in febrile seizures | Q40363396 | ||
| Histamine in cerebrospinal fluid of children with febrile convulsions | Q40688399 | ||
| Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole | Q44923257 | ||
| Histamine H3-receptor-induced attenuation of norepinephrine exocytosis: a decreased protein kinase a activity mediates a reduction in intracellular calcium | Q45015192 | ||
| Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia | Q45023804 | ||
| H3 autoreceptors modulate histamine synthesis through calcium/calmodulin- and cAMP-dependent protein kinase pathways. | Q45091226 | ||
| Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo | Q45100557 | ||
| Role of histaminergic neurons in development of epileptic seizures in EL mice | Q45153402 | ||
| Activity-dependent neuroprotection and cAMP response element-binding protein (CREB): kinase coupling, stimulus intensity, and temporal regulation of CREB phosphorylation at serine 133. | Q45249977 | ||
| MEK and ERK protect hypoxic cortical neurons via phosphorylation of Bad. | Q45253403 | ||
| Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults. | Q45956897 | ||
| Prevention of brain infarction by postischemic administration of histidine in rats | Q46394863 | ||
| Histamine H(1) and H(3) receptors in the rat thalamus and their modulation after systemic kainic acid administration | Q46495117 | ||
| Inhibition of GSK3beta is a common event in neuroprotection by different survival factors | Q46541261 | ||
| The histaminergic signaling system exerts a neuroprotective role against neurodegenerative-induced processes in the hamster. | Q46564586 | ||
| Neuroprotective effect of the new thiadiazolidinone NP00111 against oxygen-glucose deprivation in rat hippocampal slices: implication of ERK1/2 and PPARgamma receptors | Q46601596 | ||
| Histamine induces neural stem cell proliferation and neuronal differentiation by activation of distinct histamine receptors. | Q46639170 | ||
| Transient changes in the limbic histaminergic system after systemic kainic acid-induced seizures | Q46682635 | ||
| Postischemic regulation of central histamine receptors | Q46718627 | ||
| Specific cerebral heat shock proteins and histamine receptor cross-talking mechanisms promote distinct lead-dependent neurotoxic responses in teleosts | Q46876803 | ||
| Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells. | Q46890505 | ||
| Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system. | Q46911546 | ||
| Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways. | Q46944737 | ||
| Clobenpropit (VUF-9153), a new histamine H3 receptor antagonist, inhibits electrically induced convulsions in mice | Q48087726 | ||
| Chronic activation of CREB and p90RSK in human epileptic hippocampus | Q48129418 | ||
| Reduced histamine levels and H3 receptor antagonist-induced histamine release in the amygdala of Apoe-/- mice | Q48133951 | ||
| NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders | Q48157997 | ||
| Beneficial interaction between clobenpropit and pyridoxine in prevention of electroshock-induced seizures in mice: lack of histaminergic mechanisms. | Q48181447 | ||
| Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy | Q48201269 | ||
| Ultrastructural and transcriptional profiling of neuropathological misregulation of CREB function | Q48235161 | ||
| Histamine 1 receptor knock out mice show age-dependent susceptibility to status epilepticus and consequent neuronal damage | Q48257620 | ||
| Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylenetetrazol model | Q48262417 | ||
| Terfenadine induces toxicity in cultured cerebellar neurons: a role for glutamate receptors. | Q48264053 | ||
| In vivo modulation of rat hypothalamic histamine release by the histamine H3 receptor ligands, immepip and clobenpropit. Effects of intrahypothalamic and peripheral application. | Q48317100 | ||
| Effect of thioperamide, a histamine H3 receptor antagonist, on electrically induced convulsions in mice | Q48318221 | ||
| Aggravation of ischemic neuronal damage in the rat hippocampus by impairment of histaminergic neurotransmission | Q48344607 | ||
| Histamine H1 receptors in complex partial seizures. | Q48344921 | ||
| Lesion of the tuberomammillary nucleus E2-region attenuates postictal seizure protection in rats | Q48349978 | ||
| Proconvulsive effects of histamine H1-antagonists on electrically-induced seizure in developing mice | Q48389556 | ||
| The effects of histamine H3-receptor antagonists on amygdaloid kindled seizures in rats | Q48395108 | ||
| Histaminergic mechanisms in amygdaloid-kindled seizures in rats | Q48433993 | ||
| Mechanism of imipramine-induced seizures in amygdala-kindled rats | Q48445673 | ||
| Glutamatergic regulation of histamine release from rat hypothalamus | Q48506474 | ||
| Spatial organization and morphometric characteristics of histaminergic neurons in the rat brain. | Q48563076 | ||
| Histamine receptors in the brain. | Q48575174 | ||
| Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats | Q48617262 | ||
| Histamine in brain--its role in regulation of seizure susceptibility | Q48628402 | ||
| Centrally acting histamine H1 antagonists promote the development of amygdala kindling in rats | Q48888730 | ||
| Increased PLA2 activity in the hippocampus of patients with temporal lobe epilepsy and psychosis | Q48966025 | ||
| Hippocampal neuronal death induced by kainic acid and restraint stress is suppressed by exercise | Q49101436 | ||
| Biphasic action of the histamine precursor L-histidine in the rat kindling model of epilepsy | Q49118553 | ||
| Sensitivity of histamine H3 receptor agonist-stimulated [35S]GTP gamma[S] binding to pertussis toxin | Q49160810 | ||
| Participation of GABAergic and histaminergic systems in inhibiting amygdaloid kindled seizures. | Q51393707 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neurodegeneration | Q1755122 |
| P304 | page(s) | 1398-1414 | |
| P577 | publication date | 2012-12-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives | |
| P478 | volume | 167 |
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| Q49167073 | Anticonvulsant and reproductive toxicological studies of the imidazole-based histamine H3R antagonist 2-18 in mice. |
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| Q64228128 | Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats |
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