Molecular mechanisms in spindle positioning: structures and new concepts

scientific article published on November 9, 2012

Molecular mechanisms in spindle positioning: structures and new concepts is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CEB.2012.10.005
P953full work available online athttps://api.elsevier.com/content/article/PII:S0955067412001688?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0955067412001688?httpAccept=text/xml
P698PubMed publication ID23142476

P2093author name stringDimitris Liakopoulos
Lea Stevermann
P2860cites workGuanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modulesQ24298323
Cortical dynein is critical for proper spindle positioning in human cellsQ24300064
LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA PathwaysQ27671529
Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)Q27675508
Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisionsQ27676217
Mechanism for astral microtubule capture by cortical Bud6p priming spindle polarity in S. cerevisiae.Q27930519
Spindle Pole Bodies Exploit the Mitotic Exit Network in Metaphase to Drive Their Age-Dependent SegregationQ27937451
Cell division orientation and planar cell polarity pathwaysQ28245191
Asymmetric cell divisions promote stratification and differentiation of mammalian skinQ29620393
Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientationQ29871463
The effector domain of human Dlg tumor suppressor acts as a switch that relieves autoinhibition of kinesin-3 motor GAKIN/KIF13B.Q30157896
Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical PinsQ30430174
Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cellsQ39797461
Inscuteable Regulates the Pins-Mud Spindle Orientation PathwayQ40274864
Role of inscuteable in orienting asymmetric cell divisions in DrosophilaQ42522271
Planar polarization of the atypical myosin Dachs orients cell divisions in DrosophilaQ42573858
Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisionsQ43121393
Regulation of mitotic spindle asymmetry by SUMO and the spindle-assembly checkpoint in yeastQ43525495
aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division.Q45204952
Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblastsQ47070895
Tre1 GPCR Signaling Orients Stem Cell Divisions in the Drosophila Central Nervous SystemQ47071130
Cnn Dynamics Drive Centrosome Size Asymmetry to Ensure Daughter Centriole Retention in Drosophila NeuroblastsQ47071907
Mitotic spindle misorientation in cancer – out of alignment and into the fireQ47793757
Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.Q51915523
PtdIns(3,4,5)P3 regulates spindle orientation in adherent cellsQ51970435
Ubiquitylation regulates interactions of astral microtubules with the cleavage apparatusQ53315043
External forces control mitotic spindle positioningQ60228249
Asymmetric loading of Kar9 onto spindle poles and microtubules ensures proper spindle alignmentQ73034919
LGN regulates mitotic spindle orientation during epithelial morphogenesisQ30434467
Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epitheliaQ30437856
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent mannerQ30479119
Dynactin function in mitotic spindle positioning.Q30481860
Motor- and tail-dependent targeting of dynein to microtubule plus ends and the cell cortexQ30487290
Dual role of Cdc42 in spindle orientation control of adherent cellsQ30487617
Regulated offloading of cytoplasmic dynein from microtubule plus ends to the cortexQ30500353
Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule astersQ30506063
ABL1 regulates spindle orientation in adherent cells and mammalian skin.Q30512982
Dynein tethers and stabilizes dynamic microtubule plus endsQ30513994
NuMA after 30 years: the matrix revisited.Q34097270
Cell adhesion in regulation of asymmetric stem cell divisionQ34168468
Structure of an enzyme-derived phosphoprotein recognition domainQ34251318
The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafishQ34433582
A model for cleavage plane determination in early amphibian and fish embryosQ34540517
Influence of cell geometry on division-plane positioningQ34620834
Drosophila neuroblasts retain the daughter centrosome.Q34769087
Asymmetric cell divisions promote Notch-dependent epidermal differentiationQ34796271
Fly meets yeast: checking the correct orientation of cell divisionQ35188323
Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientationQ35503704
How signaling between cells can orient a mitotic spindle.Q35569313
The Rap1-Rgl-Ral signaling network regulates neuroblast cortical polarity and spindle orientationQ35670607
A novel patch assembly domain in Num1 mediates dynein anchoring at the cortex during spindle positioningQ35841747
Spindle Position in Symmetric Cell Divisions during Epiboly Is Controlled by Opposing and Dynamic Apicobasal ForcesQ35903531
Control of the mitotic cleavage plane by local epithelial topologyQ36378980
Cell shape and cell divisionQ36625784
Cell regulation by the Apc protein Apc as master regulator of epithelia.Q37116480
The actin cytoskeleton in spindle assembly and positioningQ37414777
Spindle orientation during asymmetric cell divisionQ37428762
Function of dynein in budding yeast: mitotic spindle positioning in a polarized cellQ37463946
Rap1, a mercenary among the Ras-like GTPasesQ37671129
Elaborating polarity: PAR proteins and the cytoskeletonQ37838101
Balancing self‐renewal and differentiation by asymmetric division: Insights from brain tumor suppressors in Drosophila neural stem cellsQ37979739
Revolving movement of a dynamic cluster of actin filaments during mitosisQ39640040
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)816-824
P577publication date2012-11-09
P1433published inCurrent Opinion in Cell BiologyQ13505682
P1476titleMolecular mechanisms in spindle positioning: structures and new concepts
P478volume24

Reverse relations

cites work (P2860)
Q27310178A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis
Q26824247Atypical centrioles during sexual reproduction
Q38677606Cell adhesion molecule control of planar spindle orientation.
Q35650696Cell size modulates oscillation, positioning and length of mitotic spindles
Q38248934Centrosome positioning in polarized cells: common themes and variations.
Q39002172Chirality of the cytoskeleton in the origins of cellular asymmetry
Q39087938EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells
Q47103381Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.
Q47771280Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.
Q50531453Kar9 Controls the Cytoplasm by Visiting the Nucleus.
Q41754204Kar9 controls the nucleocytoplasmic distribution of yeast EB1.
Q27318775Live cell interferometry quantifies dynamics of biomass partitioning during cytokinesis
Q51607668Mahogunin-mediated regulation of Gαi localisation during mitosis and its effect on spindle positioning
Q35087768Mechanisms of regulating tissue elongation in Drosophila wing: impact of oriented cell divisions, oriented mechanical forces, and reduced cell size
Q24295713RanGTP and CLASP1 cooperate to position the mitotic spindle
Q40216598The GPSM2/LGN GoLoco motifs are essential for hearing
Q38537596Ubiquitin in regulation of spindle apparatus and its positioning: implications in development and disease

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