| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1029143329 |
| P356 | DOI | 10.1038/NRC3877 |
| P698 | PubMed publication ID | 25592647 |
| P2093 | author name string | Suk-Chul Bae | |
| Yoshiaki Ito | |||
| Linda Shyue Huey Chuang | |||
| P2860 | cites work | Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein | Q24292027 |
| Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation | Q24300183 | ||
| Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia | Q24309601 | ||
| RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis | Q24310469 | ||
| Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia | Q24311601 | ||
| AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization | Q24311698 | ||
| Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage | Q24314457 | ||
| Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma | Q24339585 | ||
| A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator | Q24534123 | ||
| Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter | Q24537942 | ||
| Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer | Q24654971 | ||
| Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta | Q27630690 | ||
| A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis | Q27678844 | ||
| Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone. | Q36682092 | ||
| Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks | Q36688585 | ||
| Identification of RUNX3 as a component of the MST/Hpo signaling pathway | Q36784391 | ||
| RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking. | Q36877220 | ||
| RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α | Q36971996 | ||
| Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells | Q37000350 | ||
| RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes | Q37013889 | ||
| Cyclin D1-cdk4 induce runx2 ubiquitination and degradation | Q37113937 | ||
| Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells | Q37123913 | ||
| The quest for the 1p36 tumor suppressor | Q37138877 | ||
| MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma | Q37175182 | ||
| Oncogene-induced senescence: an essential role for Runx | Q37234252 | ||
| Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity | Q37245044 | ||
| DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo | Q37263155 | ||
| Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells | Q37339049 | ||
| Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation | Q37339719 | ||
| Allelic imbalance at 1p36 may predict prognosis of chemoradiation therapy for bladder preservation in patients with invasive bladder cancer | Q37355456 | ||
| RUNX proteins in transcription factor networks that regulate T-cell lineage choice | Q37376016 | ||
| Is Runx a linchpin for developmental signaling in metazoans? | Q37388143 | ||
| Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter | Q28146024 | ||
| The RUNX genes: gain or loss of function in cancer | Q28247901 | ||
| Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation | Q28261166 | ||
| Whole-genome analysis informs breast cancer response to aromatase inhibition | Q28269291 | ||
| BET domain co-regulators in obesity, inflammation and cancer | Q28269301 | ||
| RUNX3 has an oncogenic role in head and neck cancer | Q28475605 | ||
| Causal relationship between the loss of RUNX3 expression and gastric cancer | Q28509530 | ||
| Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB | Q28589970 | ||
| Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments | Q28590882 | ||
| Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia | Q28591205 | ||
| Elephant shark genome provides unique insights into gnathostome evolution | Q28660739 | ||
| CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer | Q29614277 | ||
| A molecular signature of metastasis in primary solid tumors | Q29614442 | ||
| Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms | Q29618586 | ||
| Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions | Q30435146 | ||
| Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles. | Q30443541 | ||
| The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene | Q31047666 | ||
| PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis | Q32884406 | ||
| A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation | Q32884462 | ||
| Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity | Q32884501 | ||
| The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations. | Q32884582 | ||
| Runx3 interacts with DNA repair protein Ku70. | Q33292295 | ||
| Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia | Q33330210 | ||
| Runx expression is mitogenic and mutually linked to Wnt activity in blastula-stage sea urchin embryos | Q33385660 | ||
| Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines | Q33532630 | ||
| Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy | Q33577472 | ||
| Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis | Q33697376 | ||
| Runx1 is a tumor suppressor gene in the mouse gastrointestinal tract. | Q33711292 | ||
| Cbfβ deletion in mice recapitulates cleidocranial dysplasia and reveals multiple functions of Cbfβ required for skeletal development. | Q33767459 | ||
| TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells | Q33779910 | ||
| Lozenge directly activates argos and klumpfuss to regulate programmed cell death | Q33780707 | ||
| RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53. | Q33883483 | ||
| The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts | Q33953806 | ||
| Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. | Q34002132 | ||
| Regulation of bone development and extracellular matrix protein genes by RUNX2. | Q37569808 | ||
| t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1 | Q37627380 | ||
| RUNX3 is multifunctional in carcinogenesis of multiple solid tumors | Q37720402 | ||
| A genome-wide regulatory network identifies key transcription factors for memory CD8⁺ T-cell development. | Q37723628 | ||
| TGFbeta signalling: a complex web in cancer progression | Q37760038 | ||
| RUNX1 translocations and fusion genes in malignant hemopathies | Q37822736 | ||
| The RUNX family in breast cancer: relationships with estrogen signaling | Q38050410 | ||
| RUNX family: Regulation and diversification of roles through interacting proteins | Q38062515 | ||
| DNA methylation-based biomarkers in bladder cancer | Q38102879 | ||
| Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia | Q38287713 | ||
| Runt-related transcription factor 1 (RUNX1) stimulates tumor suppressor p53 protein in response to DNA damage through complex formation and acetylation | Q38320046 | ||
| Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains | Q38327163 | ||
| A differential gene expression profile reveals overexpression of RUNX1/AML1 in invasive endometrioid carcinoma. | Q38333031 | ||
| Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma | Q38481726 | ||
| Addiction of t(8;21) and inv(16) acute myeloid leukemia to native RUNX1. | Q39093568 | ||
| Runt-related transcription factor 2 (RUNX2) inhibits p53-dependent apoptosis through the collaboration with HDAC6 in response to DNA damage | Q39160361 | ||
| RUNX3 inhibits hypoxia-inducible factor-1α protein stability by interacting with prolyl hydroxylases in gastric cancer cells | Q39173452 | ||
| Runx3 protects gastric epithelial cells against epithelial-mesenchymal transition-induced cellular plasticity and tumorigenicity | Q39296192 | ||
| Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma | Q39367341 | ||
| RUNX3 functions as an oncogene in ovarian cancer | Q39536608 | ||
| Loss of Runx3 is a key event in inducing precancerous state of the stomach | Q39601033 | ||
| Rb regulates fate choice and lineage commitment in vivo | Q39671069 | ||
| Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells. | Q39808530 | ||
| RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors | Q39914225 | ||
| RUNX3 protein is overexpressed in human epithelial ovarian cancer | Q39927217 | ||
| Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells | Q39930114 | ||
| A regulatory circuit controlling Itch-mediated p73 degradation by Runx. | Q39950945 | ||
| Deletion mapping on chromosome 1p in well-differentiated gastric cancer | Q39993827 | ||
| Physical and functional interaction of Runt-related protein 1 with hypoxia-inducible factor-1alpha | Q40096853 | ||
| The transcription factor Runx3 represses the neurotrophin receptor TrkB during lineage commitment of dorsal root ganglion neurons | Q40116776 | ||
| Genomic and functional evidence for an ARID1A tumor suppressor role | Q40134611 | ||
| Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells | Q40195895 | ||
| RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer | Q40259898 | ||
| RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells | Q40337065 | ||
| RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors. | Q40360949 | ||
| AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression | Q40595051 | ||
| RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress | Q40708275 | ||
| Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers | Q40760185 | ||
| Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene | Q40866240 | ||
| Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle | Q40903207 | ||
| Genomic instability in 1p and human malignancies | Q41170258 | ||
| Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL. | Q35816648 | ||
| Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. | Q35853581 | ||
| Stabilization of RNT-1 protein, runt-related transcription factor (RUNX) protein homolog of Caenorhabditis elegans, by oxidative stress through mitogen-activated protein kinase pathway | Q35880035 | ||
| Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2. | Q35889648 | ||
| Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes | Q35922634 | ||
| Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling | Q36117276 | ||
| Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. | Q36174127 | ||
| Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential. | Q36288903 | ||
| Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures | Q36293998 | ||
| Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma | Q36322562 | ||
| Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation | Q36329898 | ||
| Increased dosage of the RUNX1/AML1 gene: a third mode of RUNX leukemia? | Q36359355 | ||
| Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation | Q36407144 | ||
| Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene | Q36552332 | ||
| The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability | Q36561099 | ||
| Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells | Q36652900 | ||
| Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies. | Q41227818 | ||
| Functional interplay between p63 and p53 controls RUNX1 function in the transition from proliferation to differentiation in human keratinocytes. | Q41984066 | ||
| Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif. | Q42152378 | ||
| RUNX3 protein is overexpressed in human basal cell carcinomas | Q42496689 | ||
| Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts | Q42819809 | ||
| RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53. | Q42829128 | ||
| Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme | Q43055867 | ||
| Runx3 is required for the differentiation of lung epithelial cells and suppression of lung cancer. | Q43130014 | ||
| CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. | Q43239447 | ||
| High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia | Q44654291 | ||
| The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo | Q45345510 | ||
| The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation | Q45345527 | ||
| RNT-1, the C. elegans homologue of mammalian RUNX transcription factors, regulates body size and male tail development | Q47069273 | ||
| Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. | Q48075133 | ||
| Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. | Q48860347 | ||
| RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. | Q50335772 | ||
| The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia. | Q50335773 | ||
| Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts | Q51017945 | ||
| RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation. | Q51771337 | ||
| The C. elegans RUNX transcription factor RNT-1/MAB-2 is required for asymmetrical cell division of the T blast cell. | Q52036832 | ||
| Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. | Q52111650 | ||
| Distinct in vivo requirements for establishment versus maintenance of transcriptional repression. | Q52116650 | ||
| RUNX1 DNA-binding mutants, associated with minimally differentiated acute myelogenous leukemia, disrupt myeloid differentiation. | Q52576341 | ||
| Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects. | Q52652395 | ||
| C-terminal mutation of RUNX1 attenuates the DNA-damage repair response in hematopoietic stem cells. | Q53226362 | ||
| RUNX3 in oncogenic and anti-oncogenic signaling in gastrointestinal cancers. | Q53288339 | ||
| Prognostic implication of immunohistochemical Runx2 expression in osteosarcoma. | Q53499493 | ||
| Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation. | Q54515107 | ||
| Proviral insertion indicates a dominant oncogenic role for Runx1/AML-1 in T-cell lymphoma. | Q54798575 | ||
| Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression | Q57129723 | ||
| The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia | Q73046772 | ||
| A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc | Q73270837 | ||
| Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta-selection | Q74754525 | ||
| Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult | Q81152616 | ||
| Runx2 and MYC collaborate in lymphoma development by suppressing apoptotic and growth arrest pathways in vivo | Q82606388 | ||
| Nicotinamide inhibits growth of carcinogen induced mouse bladder tumor and human bladder tumor xenograft through up-regulation of RUNX3 and p300 | Q83927529 | ||
| Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. | Q34030648 | ||
| Chromosome translocations and covert leukemic clones are generated during normal fetal development | Q34032151 | ||
| Sequence analysis of mutations and translocations across breast cancer subtypes | Q34032470 | ||
| RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD. | Q34042783 | ||
| Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation | Q34045766 | ||
| Runt and Lozenge function in Drosophila development | Q34098455 | ||
| The RUNX3 gene--sequence, structure and regulated expression | Q34104024 | ||
| Unexpected repertoire of metazoan transcription factors in the unicellular holozoan Capsaspora owczarzaki | Q34150586 | ||
| Selective activation of p53-mediated tumour suppression in high-grade tumours | Q34151826 | ||
| Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome | Q34231008 | ||
| Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer | Q34258504 | ||
| AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis | Q34299077 | ||
| Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer. | Q34303695 | ||
| Stage-specific sensitivity to p53 restoration during lung cancer progression. | Q34412341 | ||
| T helper 17 cells play a critical pathogenic role in lung cancer | Q34413917 | ||
| The Role of RUNX2 in Osteosarcoma Oncogenesis | Q34423871 | ||
| Targeting transcription regulation in cancer with a covalent CDK7 inhibitor | Q34429918 | ||
| Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3. | Q34452491 | ||
| mab-2 encodes RNT-1, a C. elegans Runx homologue essential for controlling cell proliferation in a stem cell-like developmental lineage | Q34461185 | ||
| The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis | Q34718167 | ||
| Runx1 modulates developmental, but not injury-driven, hair follicle stem cell activation. | Q34747058 | ||
| An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome | Q34820210 | ||
| p53--a Jack of all trades but master of none | Q35004843 | ||
| A role for RUNX3 in inflammation-induced expression of IL23A in gastric epithelial cells. | Q35018677 | ||
| Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms | Q35024882 | ||
| RUNX transcription factors as key targets of TGF-beta superfamily signaling | Q35062437 | ||
| AML1/RUNX1 phosphorylation by cyclin-dependent kinases regulates the degradation of AML1/RUNX1 by the anaphase-promoting complex | Q35131768 | ||
| The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1. | Q35544219 | ||
| RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the making | Q35642451 | ||
| The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation | Q35650662 | ||
| Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2. | Q35652284 | ||
| Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility | Q35762938 | ||
| Structure and regulated expression of mammalian RUNX genes | Q35779684 | ||
| Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia | Q35779731 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 81-95 | |
| P577 | publication date | 2015-01-16 | |
| P1433 | published in | Nature Reviews Cancer | Q641657 |
| P1476 | title | The RUNX family: developmental regulators in cancer | |
| P478 | volume | 15 |
| Q28550430 | A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells |
| Q51097592 | A Regulatory Role for RUNX1, RUNX3 in the Maintenance of Genomic Integrity. |
| Q55076813 | A feedback loop consisting of RUNX2/LncRNA-PVT1/miR-455 is involved in the progression of colorectal cancer. |
| Q37688549 | A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice |
| Q90282411 | A novel transcriptional network for the androgen receptor in human epididymis epithelial cells |
| Q38658747 | A positive feedback loop promotes HIF-1α stability through miR-210-mediated suppression of RUNX3 in paraquat-induced EMT. |
| Q89475542 | A role for CBFβ in maintaining the metastatic phenotype of breast cancer cells |
| Q42635937 | Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts |
| Q40723774 | Addiction to Runx1 is partially attenuated by loss of p53 in the Eµ-Myc lymphoma model |
| Q42359651 | Aurora kinase and RUNX: Reaching beyond transcription |
| Q37183604 | Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression |
| Q47134182 | Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells |
| Q36064594 | BST2 Mediates Osteoblast Differentiation via the BMP2 Signaling Pathway in Human Alveolar-Derived Bone Marrow Stromal Cells |
| Q47436328 | Biomechanical regulation of drug sensitivity in an engineered model of human tumor |
| Q92618977 | CBFβ/RUNX3-miR10b-TIAM1 molecular axis inhibits proliferation, migration, and invasion of gastric cancer cells |
| Q92999945 | CROX (Cluster Regulation of RUNX) as a Potential Novel Therapeutic Approach |
| Q42378493 | Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity |
| Q33437471 | Clinical characteristics and platelet phenotype in a family with RUNX1 mutated thrombocytopenia. |
| Q89634514 | Complex Interplay between the RUNX Transcription Factors and Wnt/β-Catenin Pathway in Cancer: A Tango in the Night |
| Q38728190 | Core binding factor (CBF) is required for Epstein-Barr virus EBNA3 proteins to regulate target gene expression |
| Q39181397 | Covalent Modifications of RUNX Proteins: Structure Affects Function |
| Q35947699 | Differentially Expressed MicroRNAs in Meningiomas Grades I and II Suggest Shared Biomarkers with Malignant Tumors |
| Q50077138 | Emerging role of RUNX3 in the regulation of tumor microenvironment. |
| Q36140873 | Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs) |
| Q57214597 | Ethanol Extract of Turcz. ex Benth Inhibits Metastasis by Downregulation of Runx-2 in Mouse Colon Cancer Cells |
| Q55355645 | Expression levels of the runt-related transcription factor 1 and 3 genes in the development of acute myeloid leukemia. |
| Q47552260 | Functional Analyses of RUNX3 and CaMKIINα in Ovarian Cancer Cell Lines Reveal Tumor-Suppressive Functions for CaMKIINα and Dichotomous Roles for RUNX3 Transcript Variants. |
| Q90392099 | Functional relationship between p53 and RUNX proteins |
| Q58699333 | Genetic compensation of RUNX family transcription factors in leukemia |
| Q41661754 | Genetic regulation of the RUNX transcription factor family has antitumor effects |
| Q55263355 | Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21). |
| Q37714507 | Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice. |
| Q36601446 | How do K-RAS-activated cells evade cellular defense mechanisms? |
| Q52646480 | Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations. |
| Q47437143 | Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators |
| Q55341003 | Influence of TS (rs34743033) and RUNX1 (rs2014300) gene polymorphisms on survival outcomes of fluorouracil-based chemotherapy in Chinese advanced gastric cancer patients. |
| Q97524482 | Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking |
| Q38735531 | Interferon-γ promotes double-stranded RNA-induced TLR3-dependent apoptosis via upregulation of transcription factor Runx3 in airway epithelial cells |
| Q64898951 | Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. |
| Q91848843 | Involvement of RUNX and BRD Family Members in Restriction Point |
| Q98612815 | Knockdown of circ_0000512 Inhibits Cell Proliferation and Promotes Apoptosis in Colorectal Cancer by Regulating miR-296-5p/RUNX1 Axis |
| Q36334223 | LRG1 promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation |
| Q38395972 | Lineage factors and differentiation states in lung cancer progression |
| Q52680804 | Long Noncoding RNA uc002yug.2 Activates HIV-1 Latency through Regulation of mRNA Levels of Various RUNX1 Isoforms and Increased Tat Expression. |
| Q93062897 | Lung Cancer Staging and Associated Genetic and Epigenetic Events |
| Q38441748 | MiR-146b Mediates Endotoxin Tolerance in Human Phagocytes |
| Q92999963 | Oncogenic RUNX3: A Link between p53 Deficiency and MYC Dysregulation |
| Q89777196 | Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions |
| Q37604399 | Parathyroid Hormone-Like Hormone is a Poor Prognosis Marker of Head and Neck Cancer and Promotes Cell Growth via RUNX2 Regulation |
| Q42366151 | Pathway-based discovery of genetic interactions in breast cancer |
| Q89748207 | Phosphorylation independent eIF4E translational reprogramming of selective mRNAs determines tamoxifen resistance in breast cancer |
| Q37642717 | Phylointeractomics reconstructs functional evolution of protein binding |
| Q93188516 | Profiling the epigenetic interplay of lncRNA RUNXOR and oncogenic RUNX1 in breast cancer cells by gene in situ cis-activation |
| Q36079567 | RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3. |
| Q33771657 | RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples |
| Q64902344 | RUNX family: Oncogenes or tumor suppressors (Review). |
| Q91559627 | RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation |
| Q64095564 | RUNX represses to drive neurofibromagenesis |
| Q38793717 | RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth. |
| Q92999949 | RUNX1 Dosage in Development and Cancer |
| Q36916273 | RUNX1 and FOXP3 interplay regulates expression of breast cancer related genes |
| Q90375158 | RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells |
| Q42334131 | RUNX1 and breast cancer |
| Q42709502 | RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. |
| Q52568539 | RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells. |
| Q36637143 | RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer |
| Q92348349 | RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer |
| Q90265629 | RUNX1-dependent mechanisms in biological control and dysregulation in cancer |
| Q26800112 | RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression |
| Q91689904 | RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis |
| Q91928087 | RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line |
| Q51097612 | RUNX3 and p53: How Two Tumor Suppressors Cooperate Against Oncogenic Ras? |
| Q38851800 | RUNX3 contributes to carboplatin resistance in epithelial ovarian cancer cells |
| Q40545042 | RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer |
| Q36259257 | RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC. |
| Q49196981 | RUNX3 loss turns on the dark side of TGF-beta signaling. |
| Q101051347 | RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis |
| Q64097479 | RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-point |
| Q91666331 | RUNX3 suppresses metastasis and stemness by inhibiting Hedgehog signaling in colorectal cancer |
| Q49853226 | Reciprocal regulation of YAP/TAZ by the Hippo pathway and the Small GTPase pathway. |
| Q47241645 | Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α. |
| Q38722836 | Relationship between RUNX1 and AXIN1 in ER-negative versus ER-positive Breast Cancer |
| Q38716908 | Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance. |
| Q92999956 | Role of RUNX Family Members in G1 Restriction-Point Regulation |
| Q89553222 | Role of RUNX Family Transcription Factors in DNA Damage Response |
| Q47944350 | Roles of RUNX in Hippo Pathway Signaling. |
| Q50796410 | Roles of RUNX in Solid Tumors. |
| Q40558970 | Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock |
| Q90526645 | Runt-related transcription factor 1 promotes apoptosis and inhibits neuroblastoma progression in vitro and in vivo |
| Q39181420 | Runx Genes in Breast Cancer and the Mammary Lineage. |
| Q39169246 | Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis. |
| Q33566597 | Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition |
| Q43135021 | Runx1: a new driver in neurofibromagenesis |
| Q58106010 | Runx2 was Correlated with Neurite Outgrowth and Schwann Cell Differentiation, Migration After Sciatic Nerve Crush |
| Q51338556 | Runx2, a novel regulator for goblet cell differentiation and asthma development. |
| Q38717913 | Runx2-I is an Early Regulator of Epithelial-Mesenchymal Cell Transition in the Chick Embryo |
| Q47097047 | Runx3 plays a critical role in restriction-point and defense against cellular transformation |
| Q37167523 | Silencing of RUNX2 enhances gemcitabine sensitivity of p53-deficient human pancreatic cancer AsPC-1 cells through the stimulation of TAp63-mediated cell death. |
| Q38827698 | Silencing of RUNX2 enhances gemcitabine sensitivity of p53-deficient human pancreatic cancer AsPC-1 cells through the stimulation of TAp63-mediated cell death. |
| Q52779937 | TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management. |
| Q46602221 | Tcf1 and Lef1 pack their own HDAC. |
| Q83500609 | The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies |
| Q38744455 | The Emerging Roles of RUNX Transcription Factors in Epithelial-Mesenchymal Transition |
| Q60019698 | The Genomics and Molecular Biology of Natural Killer/T-Cell Lymphoma: Opportunities for Translation |
| Q38591845 | The RUNX complex: reaching beyond haematopoiesis into immunity |
| Q92572237 | The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells |
| Q92660789 | The Role of RUNX1 in NF1-Related Tumors and Blood Disorders |
| Q92572233 | The Roles of RUNX Family Proteins in Development of Immune Cells |
| Q38743681 | The enigmatic role of RUNX1 in female-related cancers - current knowledge & future perspectives. |
| Q33796552 | The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia |
| Q47369077 | The structure of the S-layer of Clostridium difficile. |
| Q54945552 | The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis. |
| Q64065767 | The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription |
| Q37301914 | The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma |
| Q38768286 | The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1. |
| Q64071863 | Thermodynamic investigation of DNA-binding affinity of wild-type and mutant transcription factor RUNX1 |
| Q35793648 | Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements |
| Q89553219 | Tour d'Horizon of Recent Advances in RUNX Family Gene Research |
| Q38813906 | Transcription Factor Runx3 Is Induced by Influenza A Virus and Double-Strand RNA and Mediates Airway Epithelial Cell Apoptosis |
| Q37190507 | Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer |
| Q47878462 | Transcription factors-Intricate players of the bone morphogenetic protein signaling pathway |
| Q38763233 | Transcriptional and post-transcriptional regulation of NK cell development and function |
| Q45316819 | Transcriptional regulation by RUNX2 |
| Q52663565 | Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx. |
| Q39382872 | UnPAKing RUNX3 functions-Both sides of the coin |
| Q94421150 | UnPAKing RUNX3 functions–Both sides of the coin |
| Q42672131 | Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function |
| Q47330690 | Wnt/β-Catenin Signaling Activates Expression of the Bone-Related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types |
| Q57815287 | is a RUNX1 target gene and promotes migration of NSCLC cells |
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