| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Fang Cao | |
| Yi Miao | |||
| Peijun Liu | |||
| Kedong Xu | |||
| P2860 | cites work | Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer | Q24302626 |
| A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain | Q24307607 | ||
| Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division | Q24337491 | ||
| The Hippo Signaling Pathway in Development and Cancer | Q24603986 | ||
| Wnt/β-catenin signaling and disease | Q26823272 | ||
| Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl | Q27681660 | ||
| The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p | Q27933359 | ||
| Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9 | Q27935690 | ||
| The WD repeat: a common architecture for diverse functions | Q28143827 | ||
| A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization | Q28214962 | ||
| The exocyst complex in polarized exocytosis | Q28252102 | ||
| EMT in developmental morphogenesis | Q28286655 | ||
| Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis | Q28507997 | ||
| Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice | Q28586326 | ||
| LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation | Q29977751 | ||
| WD40 proteins propel cellular networks. | Q30156873 | ||
| Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: entosis without matrix detachment | Q30514271 | ||
| lgl Regulates the Hippo Pathway Independently of Fat/Dachs, Kibra/Expanded/Merlin and dRASSF/dSTRIPAK. | Q33820271 | ||
| A protein product of the Drosophila recessive tumor gene, l (2) giant gl, potentially has cell adhesion properties | Q33929241 | ||
| Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells | Q33953411 | ||
| Snail: More than EMT | Q33977450 | ||
| Cell polarity in eggs and epithelia: parallels and diversity | Q34118022 | ||
| Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye. | Q34283595 | ||
| The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo | Q34356325 | ||
| Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer | Q34398455 | ||
| Expression of Hugl-1 is strongly reduced in malignant melanoma | Q34451983 | ||
| Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation | Q34460559 | ||
| Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors. | Q34570927 | ||
| Asymmetric cell divisions promote Notch-dependent epidermal differentiation | Q34796271 | ||
| Apicobasal polarization: epithelial form and function. | Q35595934 | ||
| p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase Czeta and regulates cell polarity | Q36118850 | ||
| Regulation of the DLG tumor suppressor by β-catenin | Q36129684 | ||
| Using Drosophila melanogaster to map human cancer pathways | Q36202195 | ||
| Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts | Q36229097 | ||
| Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis | Q36320849 | ||
| Connecting cancer to the asymmetric division of stem cells. | Q36431267 | ||
| Tight junctions and cell polarity. | Q36505527 | ||
| The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML. | Q36547690 | ||
| The Scribble and Par complexes in polarity and migration: friends or foes? | Q36635733 | ||
| Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth | Q37175773 | ||
| The exocyst complex in polarized exocytosis | Q37301127 | ||
| Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module | Q37333588 | ||
| Polarity proteins in migration and invasion | Q37333610 | ||
| Lgl and its phosphorylation by aPKC regulate oocyte polarity formation in Drosophila | Q37366108 | ||
| Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer | Q37457941 | ||
| Drosophila lethal giant larvae neoplastic mutant as a genetic tool for cancer modeling. | Q37480767 | ||
| Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia | Q37521313 | ||
| TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion | Q37678189 | ||
| ZEB proteins link cell motility with cell cycle control and cell survival in cancer. | Q37693583 | ||
| The Hippo pathway and apico-basal cell polarity | Q37875188 | ||
| Epithelial cell polarity, stem cells and cancer | Q37968480 | ||
| Cell polarity proteins and cancer. | Q37998815 | ||
| Apicobasal polarity and cell proliferation during development | Q38038637 | ||
| Connecting epithelial polarity, proliferation and cancer in Drosophila: the many faces of lgl loss of function | Q38176294 | ||
| Organization and execution of the epithelial polarity programme | Q38197884 | ||
| Hugl-1 induces apoptosis in esophageal carcinoma cells both in vitro and in vivo | Q39124267 | ||
| Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression | Q39850326 | ||
| Drosophila in cancer research: the first fifty tumor suppressor genes | Q40608613 | ||
| The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. | Q40664929 | ||
| Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs | Q41769266 | ||
| Aurora kinases phosphorylate Lgl to induce mitotic spindle orientation in Drosophila epithelia | Q41875956 | ||
| Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: an immunohistochemical study | Q42453047 | ||
| Drosophila nonmuscle myosin II promotes the asymmetric segregation of cell fate determinants by cortical exclusion rather than active transport | Q42454045 | ||
| Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. | Q42473975 | ||
| Loss of cell polarity protein Lgl2 in foveolar-type gastric dysplasia: correlation with expression of the apical marker aPKC-zeta | Q42478228 | ||
| Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells | Q42478774 | ||
| Regulation of Lethal giant larvae by Dishevelled | Q42485810 | ||
| The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts | Q42497218 | ||
| Role of inscuteable in orienting asymmetric cell divisions in Drosophila | Q42522271 | ||
| The Saccharomyces cerevisiae SOP1 and SOP2 genes, which act in cation homeostasis, can be functionally substituted by the Drosophila lethal(2)giant larvae tumor suppressor gene | Q42687279 | ||
| The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain | Q42771059 | ||
| The tumor suppressor Lgl1 forms discrete complexes with NMII-A and Par6α-aPKCζ that are affected by Lgl1 phosphorylation | Q42810655 | ||
| The involvement of lethal giant larvae and Wnt signaling in bottle cell formation in Xenopus embryos | Q42943491 | ||
| Ordered multisite phosphorylation of lethal giant larvae by atypical protein kinase C. | Q43201397 | ||
| Integrated activity of PDZ protein complexes regulates epithelial polarity | Q44268189 | ||
| A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. | Q44357555 | ||
| Lgl regulates Notch signaling via endocytosis, independently of the apical aPKC-Par6-Baz polarity complex. | Q45741872 | ||
| The WD-40 repeat motif of Lgl tumor suppressor proteins associated with salt tolerance and temperature sensitivity | Q45883445 | ||
| Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors | Q47070295 | ||
| Aurora A triggers Lgl cortical release during symmetric division to control planar spindle orientation | Q47072840 | ||
| Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. | Q47397341 | ||
| Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization | Q47881793 | ||
| Requirement of Drosophila I(2)gl function for survival of the germline cells and organization of the follicle cells in a columnar epithelium during oogenesis | Q48912966 | ||
| Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression. | Q51224744 | ||
| A serine-kinase associated with the p127-l(2)gl tumour suppressor of Drosophila may regulate the binding of p127 to nonmuscle myosin II heavy chain and the attachment of p127 to the plasma membrane. | Q52201244 | ||
| Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization. | Q52602094 | ||
| Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. | Q52704046 | ||
| Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition! | Q52708462 | ||
| The human Lgl polarity gene, Hugl-2, induces MET and suppresses Snail tumorigenesis. | Q53270407 | ||
| Epithelial-to-mesenchymal transition, cell polarity and stemness-associated features in malignant pleural mesothelioma | Q61851633 | ||
| The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer | Q80502357 | ||
| Immunohistochemistry for cell polarity protein lethal giant larvae 2 differentiates pancreatic intraepithelial neoplasia-3 and ductal adenocarcinoma of the pancreas from lower-grade pancreatic intraepithelial neoplasias | Q83196139 | ||
| Localization of aPKC lambda/iota and its interacting protein, Lgl2, is significantly associated with lung adenocarcinoma progression | Q95485673 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell polarity | Q189100 |
| neoplasm protein | Q66894191 | ||
| P304 | page(s) | 380-389 | |
| P577 | publication date | 2015-02-15 | |
| P1433 | published in | International Journal of Biological Sciences | Q6051326 |
| P1476 | title | Lethal (2) giant larvae: an indispensable regulator of cell polarity and cancer development | |
| P478 | volume | 11 |
| Q48158377 | A dual role of the extracellular domain of Drosophila Crumbs for morphogenesis of the embryonic neuroectoderm |
| Q37190790 | Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis |
| Q38862739 | Cell polarity proteins and spermatogenesis. |
| Q39178793 | Crosstalk of cell polarity signaling pathways. |
| Q90103107 | Drosophila Models of Cell Polarity and Cell Competition in Tumourigenesis |
| Q92021200 | Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2 |
| Q64111881 | is required for the integrity of the photoreceptor layer in the zebrafish retina |
| Q48182995 | miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila. |
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