| P2093 | author name string | Cox Terhorst | |
| | Xiaomei Wang | |
| | Roland W Herzog | |
| P2860 | cites work | Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway | Q24310325 |
| | Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells | Q24538658 |
| | Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells | Q24645614 |
| | Mechanism of oral tolerance induction to therapeutic proteins | Q26866369 |
| | Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation | Q27311412 |
| | Control of regulatory T cell development by the transcription factor Foxp3 | Q27860489 |
| | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Q27860714 |
| | Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases | Q28131652 |
| | The inhibitory cytokine IL-35 contributes to regulatory T-cell function | Q28258462 |
| | TGF-beta: a mobile purveyor of immune privilege | Q28263622 |
| | Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells | Q28289781 |
| | Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin | Q28475626 |
| | The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues | Q28510383 |
| | T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation | Q28511506 |
| | Glucocorticoid-induced TNF receptor family-related protein ligand regulates the migration of monocytes to the inflamed intestine | Q28587236 |
| | A function for interleukin 2 in Foxp3-expressing regulatory T cells | Q28590646 |
| | Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species | Q29547701 |
| | A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism | Q29614266 |
| | Mechanisms of foxp3+ T regulatory cell-mediated suppression | Q29615842 |
| | The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis | Q29616351 |
| | Regulatory T cells and immune tolerance | Q29616864 |
| | An essential role for Scurfin in CD4+CD25+ T regulatory cells | Q29618395 |
| | The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 | Q29619324 |
| | A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis | Q29619339 |
| | IL-10 inhibits cytokine production by activated macrophages | Q29619453 |
| | Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses | Q29619908 |
| | Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation | Q29620116 |
| | CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice | Q30491507 |
| | Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells | Q30873503 |
| | Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo | Q33723552 |
| | Immune tolerance induction to factor IX through B cell gene transfer: TLR9 signaling delineates between tolerogenic and immunogenic B cells | Q33724236 |
| | Long-term tolerance to factor VIII is achieved by administration of interleukin-2/interleukin-2 monoclonal antibody complexes and low dosages of factor VIII. | Q33748093 |
| | GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells | Q33752581 |
| | TGF-β induces surface LAP expression on murine CD4 T cells independent of Foxp3 induction | Q33760756 |
| | A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells | Q36974721 |
| | In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure | Q36979997 |
| | Regulatory T cells - a brief history and perspective | Q36986732 |
| | Tolerance induction by gene transfer to lymphocytes | Q36990116 |
| | Special regulatory T-cell review: Regulation of immune responses--examining the role of T cells | Q37043717 |
| | Combined Administration of a Mutant TGF-β1/Fc and Rapamycin Promotes Induction of Regulatory T Cells and Islet Allograft Tolerance | Q37155930 |
| | Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice | Q37161107 |
| | Fms-like tyrosine kinase 3 ligand increases a lung DC subset with regulatory properties in allergic airway inflammation | Q37212901 |
| | Activated B cells in autoimmune diseases: the case for a regulatory role | Q37335863 |
| | Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies | Q37342834 |
| | Immune response to FVIII in hemophilia A: an overview of risk factors | Q37370005 |
| | The role of apoptosis in immune hyporesponsiveness following AAV8 liver gene transfer | Q37393827 |
| | Anti-CD3 antibodies modulate anti-factor VIII immune responses in hemophilia A mice after factor VIII plasmid-mediated gene therapy | Q37420500 |
| | Role of regulatory T cells in tolerance to coagulation factors | Q37561470 |
| | Immunomodulation for inhibitors in hemophilia A: the important role of Treg cells | Q37803130 |
| | Parallel use of by‐passing agents in haemophilia with inhibitors: a critical review | Q37927122 |
| | Innate Immune Responses to AAV Vectors | Q37939843 |
| | T cell tolerance and immunity to commensal bacteria. | Q38011862 |
| | In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity | Q38039963 |
| | Induction of antigen-specific tolerance through hematopoietic stem cell-mediated gene therapy: the future for therapy of autoimmune disease? | Q38050613 |
| | Progress toward inducing immunologic tolerance to factor VIII | Q38090391 |
| | Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications. | Q38227343 |
| | Control of tissue-localized immune responses by human regulatory T cells | Q38265955 |
| | Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice | Q39084223 |
| | Improved induction of immune tolerance to factor IX by hepatic AAV-8 gene transfer | Q39302902 |
| | Amelioration of colitis by genetically engineered murine regulatory T cells redirected by antigen-specific chimeric receptor. | Q40003509 |
| | T regulatory-1 cells induce IgG4 production by B cells: role of IL-10. | Q40437966 |
| | Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins | Q40446327 |
| | Prevention and Reversal of Antibody Responses Against Factor IX in Gene Therapy for Hemophilia B. | Q40485786 |
| | Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation | Q41488164 |
| | Regulatory T Cells Require Mammalian Target of Rapamycin Signaling To Maintain Both Homeostasis and Alloantigen-Driven Proliferation in Lymphocyte-Replete Mice | Q41615490 |
| | Induction of tolerance to factor VIII by transient co-administration with rapamycin. | Q41824863 |
| | Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer | Q41920883 |
| | Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells. | Q41926775 |
| | Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver. | Q41972673 |
| | Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood | Q41988688 |
| | Flt3 ligand expands CD103+dendritic cells and FoxP3+T regulatory cells, and attenuates Crohn's-like murine ileitis | Q42024414 |
| | Retroviral Vectors Induce Epigenetic Chromatin Modifications and IL-10 Production in Transduced B Cells via Activation of Toll-like Receptor 2 | Q42178313 |
| | Prophylactic immune tolerance induced by changing the ratio of antigen-specific effector to regulatory T cells | Q42362478 |
| | Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood | Q42572213 |
| | Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer | Q42786561 |
| | Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation | Q42974140 |
| | Induction of antigen-specific tolerance by intrathymic injection of lentiviral vectors. | Q44122249 |
| | Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4. | Q44302983 |
| | Smad3 is essential for TGF-beta 1 to suppress IL-2 production and TCR-induced proliferation, but not IL-2-induced proliferation | Q44807473 |
| | Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells | Q44967317 |
| | Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. | Q45299244 |
| | Prevention and treatment of factor VIII inhibitors in murine hemophilia A. | Q45865107 |
| | Preventing restimulation of memory B cells in hemophilia A: a potential new strategy for the treatment of antibody-dependent immune disorders | Q45873471 |
| | Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer | Q45874902 |
| | Long-term induction of immune tolerance after blockade of CD40-CD40L interaction in a mouse model of hemophilia A. | Q45876403 |
| | Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells | Q45878833 |
| | Anti-CD3 prevents factor VIII inhibitor development in hemophilia A mice by a regulatory CD4+CD25+-dependent mechanism and by shifting cytokine production to favor a Th1 response | Q45880461 |
| | Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A. | Q45883210 |
| | Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines | Q45889051 |
| | Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation. | Q46759811 |
| | Manufacturing of large numbers of patient-specific T cells for adoptive immunotherapy: an approach to improving product safety, composition, and production capacity | Q47573453 |
| | The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis | Q47734606 |
| | Regulatory T cells: recommendations to simplify the nomenclature. | Q48624465 |
| | STAT3 regulates NF-kappaB recruitment to the IL-12p40 promoter in dendritic cells | Q50799062 |
| | STAT3 is required for Flt3L-dependent dendritic cell differentiation | Q51012505 |
| | Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells | Q51103369 |
| | Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. | Q51997055 |
| | Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+CD25+ regulatory T cells versus CD8+ memory T cells. | Q52004102 |
| | Clinical grade production of IL-10 producing regulatory Tr1 lymphocytes for cell therapy of chronic inflammatory diseases | Q52697883 |
| | Flt3 ligand expands CD4+ FoxP3+ regulatory T cells in human subjects. | Q54473462 |
| | Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells | Q54613578 |
| | An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation. | Q54736687 |
| | TGF-β1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression | Q56987564 |
| | IL-10 inhibits human T cell proliferation and IL-2 production | Q67749838 |
| | Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells | Q73612987 |
| | Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide | Q73688337 |
| | Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation | Q74080415 |
| | T cell regulation: a special job or everyone's responsibility? | Q74433979 |
| | Induction and mechanism of action of transforming growth factor‐β‐secreting Th3 regulatory cells | Q77291206 |
| | Blockade of CD40/CD40 ligand interactions prevents induction of factor VIII inhibitors in hemophilic mice but does not induce lasting immune tolerance | Q77447728 |
| | Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice | Q79445122 |
| | Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells | Q80034250 |
| | Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors | Q80444910 |
| | Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells | Q80812598 |
| | Oral tolerance | Q80945963 |
| | CD4-8- dendritic cells prime CD4+ T regulatory 1 cells to suppress antitumor immunity | Q81099175 |
| | A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells | Q81157115 |
| | IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells | Q81476292 |
| | Flt3 signaling-dependent dendritic cells protect against atherosclerosis | Q82480465 |
| | Oral tolerance | Q83849376 |
| | Induction of IL-10-producing regulatory T cells with TCR diversity by epitope-specific immunotherapy in pollinosis | Q84458232 |
| | T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development | Q85350477 |
| | Oral tolerance in the absence of naturally occurring Tregs | Q33840440 |
| | Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice | Q33859520 |
| | Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development | Q33892077 |
| | Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance | Q33897693 |
| | Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate | Q33908130 |
| | Lipopolysaccharide-Mediated IL-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and IL-27 in Macrophages | Q33919041 |
| | IL-27 is a key regulator of IL-10 and IL-17 production by human CD4+ T cells | Q33998909 |
| | Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cells | Q34107172 |
| | Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance | Q34111451 |
| | CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor | Q34116317 |
| | Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells | Q34137024 |
| | B cells regulate autoimmunity by provision of IL-10. | Q34150590 |
| | Transient B Cell Depletion or Improved Transgene Expression by Codon Optimization Promote Tolerance to Factor VIII in Gene Therapy | Q34289040 |
| | IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells | Q34318928 |
| | Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism | Q34392100 |
| | Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia. | Q34424570 |
| | Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance | Q34503328 |
| | Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression | Q34504988 |
| | Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. | Q34509694 |
| | Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy | Q34541550 |
| | Human T regulatory cells can use the perforin pathway to cause autologous target cell death | Q34551876 |
| | Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection. | Q34558853 |
| | Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis | Q34563552 |
| | Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. | Q34569888 |
| | Transforming growth factor-beta in T-cell biology | Q34572232 |
| | Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function | Q34604727 |
| | Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells | Q34609504 |
| | Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis | Q34719541 |
| | Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer | Q34729938 |
| | Development of Gene Transfer for Induction of Antigen-specific Tolerance | Q34794525 |
| | The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. | Q34801853 |
| | New immunosuppressive approaches: oral administration of CD3-specific antibody to treat autoimmunity | Q34831889 |
| | Dendritic cell control of tolerogenic responses | Q34982085 |
| | Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer | Q34985105 |
| | Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance | Q34985424 |
| | Hepatic T cells and liver tolerance | Q35038298 |
| | Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses | Q35080090 |
| | Natural versus adaptive regulatory T cells | Q35092554 |
| | B-Cell Gene Therapy for Tolerance Induction: Host but Not Donor B-Cell Derived IL-10 is Necessary for Tolerance | Q35116488 |
| | Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance | Q35119879 |
| | CD4CD8αα lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. | Q35142800 |
| | In Vivo Expansion of Regulatory T cells With IL-2/IL-2 mAb Complexes Prevents Anti-factor VIII Immune Responses in Hemophilia A Mice Treated With Factor VIII Plasmid-mediated Gene Therapy | Q35144444 |
| | AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice | Q35153203 |
| | T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse | Q35213550 |
| | Peripheral education of the immune system by colonic commensal microbiota. | Q35341308 |
| | Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells | Q35348677 |
| | Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg. | Q35583409 |
| | Immunomodulation of transgene responses following naked DNA transfer of human factor VIII into hemophilia A mice | Q35849770 |
| | Latent TGF-beta binding proteins: extracellular matrix association and roles in TGF-beta activation | Q35861493 |
| | Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins | Q36013422 |
| | Low cost industrial production of coagulation factor IX bioencapsulated in lettuce cells for oral tolerance induction in hemophilia B. | Q36037525 |
| | CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery. | Q36112863 |
| | CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. | Q36229540 |
| | The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease | Q36370178 |
| | In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes | Q36399048 |
| | Regulatory T cells: magic bullets for immunotherapy? | Q36461689 |
| | Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells | Q36640081 |
| | Inhibitor treatment in haemophilias A and B: inhibitor diagnosis | Q36661822 |
| | Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering | Q36778446 |
| | Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice | Q36843682 |
| | Inhibitor development in haemophilia B: an orphan disease in need of attention | Q36872038 |
| | Tolerogenic dendritic cells and the quest for transplant tolerance | Q36879029 |
| | Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. | Q36891917 |
| P921 | main subject | hemophilia | Q134003 |
| P1104 | number of pages | 12 | |
| P304 | page(s) | 18-29 | |
| P577 | publication date | 2015-10-07 | |
| P1433 | published in | Cellular Immunology | Q2597167 |
| P1476 | title | In vivo induction of regulatory T cells for immune tolerance in hemophilia | |
| P478 | volume | 301 | |