Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells

scientific article published on 23 October 2012

Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ADDR.2012.10.005
P932PMC publication ID3582797
P698PubMed publication ID23099275
P5875ResearchGate publication ID232704927

P50authorHenry DaniellQ30533568
P2093author name stringDheeraj Verma
Kwang-Chul Kwon
Nameirakpam D Singh
Roland Herzog
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Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylureaQ46458866
Preparation and evaluation of chitosan-ethylenediaminetetraacetic acid hydrogel films for the mucoadhesive transbuccal delivery of insulinQ46597054
Nasal delivery of insulin using bioadhesive chitosan gelsQ46886042
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Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potatoQ47614578
The role of ADP‐ribosylation and GM1‐binding activity in the mucosal immunogenicity and adjuvanticity of the Escherichia coli heat‐labile enterotoxin and Vibrio cholerae cholera toxinQ47771715
Immune response of infants to fractional doses of intradermally administered inactivated poliovirus vaccineQ47773752
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A phase 1 trial of PfCP2.9: an AMA1/MSP1 chimeric recombinant protein vaccine for Plasmodium falciparum malariaQ47885076
Immunogenicity and protective efficacy of Escherichia coli expressed Plasmodium falciparum merozoite surface protein-1(42) using human compatible adjuvantsQ48021487
Nasal drug deliveryQ48291849
Remodeling the isoprenoid pathway in tobacco by expressing the cytoplasmic mevalonate pathway in chloroplastsQ49522968
Characterization of heterologous multigene operons in transgenic chloroplasts: transcription, processing, and translationQ51421888
Expression of the cholera toxin B subunit (CT-B) in maize seeds and a combined mucosal treatment against cholera and traveler’s diarrheaQ54352501
MalariaQ55878749
Drawing lithography: three-dimensional fabrication of an ultrahigh-aspect-ratio microneedleQ57154601
Immunogenicity of a plant-derived edible chimeric EspA, Intimin and Tir of Escherichia coli O157:H7 in miceQ59274678
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Cholera toxin B subunit as a carrier protein to stimulate a mucosal immune responseQ70591810
Monomer of the B subunit of heat-labile enterotoxin from enterotoxigenic Escherichia coli has little ability to bind to GM1 ganglioside compared to its coligenoidQ70940365
Transgenic plants expressing autoantigens fed to mice to induce oral immune toleranceQ73486424
Human nasal mucosa contains antigen-presenting cells of strikingly different functional phenotypesQ73581449
Cell surface phenotype and ultramicroscopic analysis of purified human enterocytes: a possible antigen-presenting cell in the intestineQ74150936
Study on a nanoparticle system for buccal delivery of insulinQ79727645
Insulin as an autoantigen in NOD/human diabetesQ36499414
Oral delivery of bioencapsulated exendin-4 expressed in chloroplasts lowers blood glucose level in mice and stimulates insulin secretion in beta-TC6 cellsQ36504504
Buccal bioadhesive drug delivery--a promising option for orally less efficient drugsQ36530971
Cholera toxin B subunit linked to glutamic acid decarboxylase suppresses dendritic cell maturation and function.Q36551840
Novel delivery technologies for protein and peptide therapeuticsQ36570172
Present and future cholera vaccinesQ36690265
Effective plague vaccination via oral delivery of plant cells expressing F1-V antigens in chloroplasts.Q36804213
Inhibitor development in haemophilia B: an orphan disease in need of attentionQ36872038
Current challenges in non-invasive insulin delivery systems: a comparative reviewQ36946206
Expression of cholera toxin B-proinsulin fusion protein in lettuce and tobacco chloroplasts--oral administration protects against development of insulitis in non-obese diabetic miceQ36990434
Field production and functional evaluation of chloroplast-derived interferon-alpha2bQ37000665
Chloroplast vector systems for biotechnology applicationsQ37023309
Albinterferon alpha-2b: a genetic fusion protein for the treatment of chronic hepatitis C.Q37027164
Apical membrane antigen 1: a malaria vaccine candidate in reviewQ37069649
Cholera vaccines for the developing world.Q37138956
Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and functionQ37182165
Transdermal drug deliveryQ37238479
Barrier properties of mucusQ37365829
Immune response to FVIII in hemophilia A: an overview of risk factorsQ37370005
Minimally invasive insulin delivery in subjects with type 1 diabetes using hollow microneedlesQ37426334
Infections and autoimmunity--friends or foes?Q37567077
Plant-made vaccine antigens and biopharmaceuticalsQ37616370
Prevention of bubonic and pneumonic plague using plant-derived vaccinesQ37636760
Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunitQ37657673
Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4.Q37682917
Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in miceQ30402980
Stable expression of Gal/GalNAc lectin of Entamoeba histolytica in transgenic chloroplasts and immunogenicity in mice towards vaccine development for amoebiasisQ30424547
Hypoglycaemic effect of a novel insulin buccal formulation on rabbitsQ30868752
Uptake of poly(D,L-lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivoQ31045989
Discovering and improving novel peptide therapeuticsQ33349255
Investigation on the synergistic effect of a combination of chemical enhancers and modulated iontophoresis for transdermal delivery of insulinQ33545395
The clinical-grade 42-kilodalton fragment of merozoite surface protein 1 of Plasmodium falciparum strain FVO expressed in Escherichia coli protects Aotus nancymai against challenge with homologous erythrocytic-stage parasitesQ33558061
Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable deliveryQ33596284
Immunotherapy of type 1 diabetes: where are we and where should we be going?Q33815506
Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B miceQ33859520
The NOD mouse model of type 1 diabetes: as good as it gets?Q33865111
Modulation of immune responses following antigen administration by mucosal routeQ33869471
Plague as a biological weapon: medical and public health management. Working Group on Civilian BiodefenseQ33901607
Evolving trends in insulin delivery in pursuit of improvements in diabetes managementQ33932057
Collaboration of epithelial cells with organized mucosal lymphoid tissues.Q33955758
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP).Q33989220
C-peptide is a bioactive peptideQ34002043
Vaccine efficacy of recombinant Plasmodium falciparum merozoite surface protein 1 in malaria-naive, -exposed, and/or -rechallenged Aotus vociferans monkeysQ34003578
Specificity of the protective antibody response to apical membrane antigen 1Q34007362
Cholera toxin - a foe & a friend.Q34026162
A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responsesQ34161016
Factors and strategies for improving buccal absorption of peptides.Q34167000
Plant-based vaccine: mice immunized with chloroplast-derived anthrax protective antigen survive anthrax lethal toxin challengeQ34194628
Mapping the T helper cell response to acid α-glucosidase in Pompe miceQ34228856
Systematic review of mucosal immunity induced by oral and inactivated poliovirus vaccines against virus shedding following oral poliovirus challengeQ34244892
Protection conferred by recombinant Yersinia pestis antigens produced by a rapid and highly scalable plant expression systemQ34250117
Vaccination against bubonic and pneumonic plagueQ34310210
Overcoming skin's barrier: the search for effective and user-friendly drug deliveryQ34322370
Robust recall and long-term memory T-cell responses induced by prime-boost regimens with heterologous live viral vectors expressing human immunodeficiency virus type 1 Gag and Env proteinsQ34343020
A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis.Q34343581
Mucosal immunity and vaccinesQ34409172
The pancreas in human type 1 diabetesQ34496850
Protein transduction technologyQ34534961
Metallothionein expression in chloroplasts enhances mercury accumulation and phytoremediation capabilityQ34628765
Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit.Q34629092
A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvantsQ34678990
Bioreducible polymers for gene deliveryQ34812807
The role of incretins in glucose homeostasis and diabetes treatmentQ34901533
The immune geography of IgA induction and functionQ34903056
Interaction of cholera toxin and membrane GM1 ganglioside of small intestineQ35083242
TH1-TH2: a procrustean paradigmQ35139852
Curbing activation: proprotein convertases in homeostasis and pathologyQ35165457
A recombinant baculovirus 42-kilodalton C-terminal fragment of Plasmodium falciparum merozoite surface protein 1 protects Aotus monkeys against malaria.Q35463512
Comparison of protection induced by immunization with recombinant proteins from different regions of merozoite surface protein 1 of Plasmodium yoeliiQ35551948
Recovery of skin barrier after stratum corneum removal by microdermabrasionQ35577226
Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetesQ35618856
Unsafe injections in low-income country health settings: need for injection safety promotion to prevent the spread of blood-borne virusesQ35672048
Transgene containment by maternal inheritance: effective or elusive?Q35758721
Immune therapy for autoimmune diseasesQ35833158
Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccinationQ35865115
The mucosal immune system: from fundamental concepts to vaccine developmentQ35897681
Clinical utility gene card for: haemophilia B.Q35899385
Novel approaches to vaccine deliveryQ35924680
Chloroplast-derived vaccine antigens and other therapeutic proteinsQ36055964
Mucosal adjuvantsQ36055990
Towards an effective malaria vaccineQ36121709
Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatmentQ36338254
Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptideQ36344923
Expression of Bacillus anthracis protective antigen in transgenic chloroplasts of tobacco, a non-food/feed cropQ36349402
Receptor-mediated oral delivery of a bioencapsulated green fluorescent protein expressed in transgenic chloroplasts into the mouse circulatory systemQ36349444
Invasion-inhibitory antibodies inhibit proteolytic processing of apical membrane antigen 1 of Plasmodium falciparum merozoitesQ36349656
A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.Q36352078
Mucosal vaccines: the promise and the challengeQ36402244
Strategies to improve plasma half life time of peptide and protein drugsQ36452632
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectvaccineQ134808
P304page(s)782-799
P577publication date2012-10-23
P1433published inAdvanced Drug Delivery ReviewsQ2825362
P1476titleOral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells
P478volume65

Reverse relations

cites work (P2860)
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