scholarly article | Q13442814 |
P50 | author | David D Roberts | Q42408238 |
Katherine Cook | Q42681142 | ||
Leena Hilakivi-Clarke | Q119139100 | ||
P2093 | author name string | David R Soto-Pantoja | |
Robert Clarke | |||
M Idalia Cruz | |||
Anni Wärri | |||
Alan Zwart | |||
Pamela A G Clarke | |||
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Lipid biology of breast cancer | Q27013858 | ||
Cancer statistics, 2014 | Q27861018 | ||
GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease | Q28254667 | ||
Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer | Q28268250 | ||
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production | Q28534981 | ||
Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex | Q28567616 | ||
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Q29547646 | ||
AMPK: a nutrient and energy sensor that maintains energy homeostasis | Q29615410 | ||
Tumor cell metabolism: cancer's Achilles' heel | Q29619809 | ||
Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance | Q33556664 | ||
Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer. | Q33813981 | ||
Knockdown of estrogen receptor-α induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death | Q34072615 | ||
Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis. | Q34118737 | ||
Regulation of food intake by oleoylethanolamide | Q34403399 | ||
CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapy | Q34621578 | ||
NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer | Q34745409 | ||
Bortezomib enhances the efficacy of fulvestrant by amplifying the aggregation of the estrogen receptor, which leads to a proapoptotic unfolded protein response | Q35596882 | ||
Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer | Q35634154 | ||
Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate. | Q35855031 | ||
Heat shock 70 kDa protein 5/glucose-regulated protein 78 "AMP"ing up autophagy | Q36521680 | ||
Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness | Q36622926 | ||
Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer | Q37072811 | ||
Cancer metabolism: fatty acid oxidation in the limelight | Q37155867 | ||
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase | Q37340913 | ||
Cholesterol metabolism and resistance to tamoxifen. | Q38051937 | ||
Targeting GRP78 and antiestrogen resistance in breast cancer | Q38111800 | ||
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis | Q39843795 | ||
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis | Q40144533 | ||
Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications. | Q41578634 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen | Q42815735 | ||
Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer | Q46665995 | ||
Tamoxifen treatment for breast cancer enforces a distinct gene-expression profile on the human endometrium: an exploratory study | Q46831175 | ||
Tamoxifen and toremifene lower serum cholesterol by inhibition of delta 8-cholesterol conversion to lathosterol in women with breast cancer. | Q53971615 | ||
Polyunsaturated fatty acid-induced cytotoxicity against tumor cells and its relationship to lipid peroxidation | Q68277142 | ||
Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids | Q68740692 | ||
Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions | Q73639378 | ||
Linoleic acid induces MCP-1 gene expression in human microvascular endothelial cells through an oxidative mechanism | Q74179062 | ||
Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation | Q81127015 | ||
ER stress triggers MCP-1 expression through SET7/9-induced histone methylation in the kidneys of db/db mice | Q87146747 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 5657-5670 | |
P577 | publication date | 2016-10-01 | |
P1433 | published in | Cancer Research | Q326097 |
P1476 | title | Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer | |
P478 | volume | 76 |
Q38621233 | "UPRegulation" of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses |
Q64096895 | A Pathophysiological Model of Non-Alcoholic Fatty Liver Disease Using Precision-Cut Liver Slices |
Q90593641 | Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy |
Q99418051 | Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells |
Q61796567 | ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness" |
Q37618279 | Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice |
Q92282534 | Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response |
Q90441712 | GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells |
Q38692967 | GRP78 at the Centre of the Stage in Cancer and Neuroprotection |
Q92508950 | GRP94 Is Involved in the Lipid Phenotype of Brain Metastatic Cells |
Q64238292 | Immune targets in the tumor microenvironment treated by radiotherapy |
Q89599348 | Impairment of Membrane Lipid Homeostasis by Bichalcone Analog TSWU-BR4 Attenuates Function of GRP78 in Regulation of the Oxidative Balance and Invasion of Cancer Cells |
Q94957210 | KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression |
Q49544341 | Perspectives of Reprogramming Breast Cancer Metabolism |
Q46556374 | Regulation of tumor-stroma interactions by the Unfolded Protein Response. |
Q98771779 | Targeting the GRP78 Pathway for Cancer Therapy |
Q57105740 | The Unfolded Protein Response in Breast Cancer |
Q42700708 | The meta and bioinformatics analysis of GRP78 expression in gastric cancer |
Q44964898 | Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness |
Q64932561 | miR‑495 enhances the efficacy of radiotherapy by targeting GRP78 to regulate EMT in nasopharyngeal carcinoma cells. |
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