scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.BBALIP.2013.03.011 |
P8608 | Fatcat ID | release_iicdwu442vhwjbgvo3hdcg54xi |
P932 | PMC publication ID | 3926128 |
P698 | PubMed publication ID | 23562840 |
P2093 | author name string | Jan Baumann | |
Christopher Sevinsky | |||
Douglas S. Conklin | |||
P2860 | cites work | Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response | Q22000747 |
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase | Q24297921 | ||
Regulation of cellular metabolism by protein lysine acetylation | Q24300091 | ||
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide | Q24305343 | ||
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth | Q24309283 | ||
Mechanism of activation of protein kinase B by insulin and IGF-1 | Q24309528 | ||
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation | Q24322925 | ||
Fatty acid synthesis: a potential selective target for antineoplastic therapy | Q24561903 | ||
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells | Q24561962 | ||
Understanding the Warburg effect: the metabolic requirements of cell proliferation | Q24604760 | ||
Comprehensive molecular portraits of human breast tumours | Q24630844 | ||
mTOR: from growth signal integration to cancer, diabetes and ageing | Q24633662 | ||
mTOR signaling in growth control and disease | Q24634174 | ||
MAM: more than just a housekeeper | Q24648220 | ||
Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells | Q40022130 | ||
Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival | Q40278693 | ||
Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells | Q40435070 | ||
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance. | Q40480010 | ||
The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation | Q40561467 | ||
The eIF-2alpha kinases and the control of protein synthesis | Q41198124 | ||
Nutrition, hormones, and breast cancer: is insulin the missing link? | Q41227904 | ||
mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes. | Q41441726 | ||
IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells | Q41527015 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains | Q42809714 | ||
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis. | Q42832143 | ||
Peroxisome proliferator-activated receptor-gamma protects ERBB2-positive breast cancer cells from palmitate toxicity. | Q43120090 | ||
Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain | Q44075031 | ||
Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c | Q44280816 | ||
Fatty acid synthetase and its mRNA are induced by progestins in breast cancer cells | Q44307619 | ||
Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin | Q44516189 | ||
A gene transcription signature of obesity in breast cancer. | Q45404516 | ||
Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells | Q50889342 | ||
Serum hormone levels in relation to reproductive and lifestyle factors in postmenopausal women (United States). | Q50890538 | ||
Regulation of SREBP1c gene expression in skeletal muscle: role of retinoid X receptor/liver X receptor and forkhead-O1 transcription factor. | Q51455793 | ||
BRCA1 and acetyl-CoA carboxylase: the metabolic syndrome of breast cancer. | Q53542028 | ||
Metabolic syndrome and the risk of breast cancer in postmenopausal women | Q57559288 | ||
The effect of dietary fat and fiber on serum estrogen concentrations in premenopausal women under controlled dietary conditions | Q72078895 | ||
New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays | Q77220709 | ||
Obesity and cancer | Q80476148 | ||
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 | Q80553475 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation | Q24678674 | ||
High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate | Q27639493 | ||
Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR | Q27647018 | ||
The phosphoinositide 3-kinase pathway | Q27860738 | ||
Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults | Q28131763 | ||
Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration | Q28235184 | ||
Asymmetrical Lipid Bilayer Structure for Biological Membranes | Q28242238 | ||
Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor | Q28250779 | ||
Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1 | Q28276509 | ||
SREBP-1c transcription factor and lipid homeostasis: clinical perspective | Q28291930 | ||
Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism | Q28297621 | ||
SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma | Q28301961 | ||
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway | Q28510620 | ||
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
Acyl-coenzyme A synthetases in metabolic control | Q28647005 | ||
Metabolic regulation of invadopodia and invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis | Q28740280 | ||
ATP-citrate lyase links cellular metabolism to histone acetylation | Q29615367 | ||
THE METABOLISM OF TUMORS IN THE BODY | Q29616202 | ||
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway | Q30425628 | ||
Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols | Q30843994 | ||
Plasmalogens in biological systems: their role in oxidative processes in biological membranes, their contribution to pathological processes and aging and plasmalogen analysis | Q33466440 | ||
Eukaryotic initiation factor eIF2. | Q33601625 | ||
An RNA interference screen identifies metabolic regulators NR1D1 and PBP as novel survival factors for breast cancer cells with the ERBB2 signature | Q33722873 | ||
Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis | Q33734679 | ||
Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage | Q33750671 | ||
PPARgamma: an essential regulator of adipogenesis and modulator of fat cell function | Q33770818 | ||
DHHC20: a human palmitoyl acyltransferase that causes cellular transformation | Q33946275 | ||
Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane | Q33963946 | ||
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics | Q33986242 | ||
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins | Q34111893 | ||
Effect of obesity on breast cancer development | Q37685762 | ||
Phosphoinositide signalling pathways in metabolic regulation | Q37762204 | ||
Effect of obesity on survival of women with breast cancer: systematic review and meta-analysis | Q37767169 | ||
Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors. | Q37888979 | ||
Obesity-induced metabolic stresses in breast and colon cancer | Q37906710 | ||
Protein palmitoylation and subcellular trafficking | Q37912382 | ||
Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis | Q38062392 | ||
N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization | Q38306703 | ||
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth | Q39470144 | ||
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis | Q39843795 | ||
Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis | Q39945691 | ||
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation | Q39972783 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis | Q40002274 | ||
ERα17p, a peptide reproducing the hinge region of the estrogen receptor α associates to biological membranes: A biophysical approach | Q34199023 | ||
The SREBP pathway--insights from Insigs and insects | Q34223258 | ||
PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation | Q34235264 | ||
CD36: a multiligand molecule | Q34406219 | ||
Coenzyme A: back in action | Q34418810 | ||
Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells | Q34613543 | ||
Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells. | Q34650973 | ||
A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression | Q34656781 | ||
Phospholipase D1 is an effector of Rheb in the mTOR pathway. | Q34786317 | ||
Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism | Q34827108 | ||
Triglyceride accumulation protects against fatty acid-induced lipotoxicity | Q34866329 | ||
Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers | Q34972623 | ||
CoA synthase is in complex with p85alphaPI3K and affects PI3K signaling pathway. | Q34983963 | ||
Role of Akt/protein kinase B in metabolism. | Q34997136 | ||
Lipotoxicity: when tissues overeat | Q35168828 | ||
Fatty acid synthase as a potential therapeutic target in cancer | Q35401716 | ||
Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation | Q35747483 | ||
KAT(ching) metabolism by the tail: insight into the links between lysine acetyltransferases and metabolism | Q35892832 | ||
Breast density, body mass index, and risk of tumor marker-defined subtypes of breast cancer | Q35918620 | ||
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. | Q35965439 | ||
Endoplasmic reticulum stress in liver disease | Q36031838 | ||
Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins. | Q36140005 | ||
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
"Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways | Q36540080 | ||
Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin | Q37110578 | ||
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
Hypoxia signalling through mTOR and the unfolded protein response in cancer | Q37290935 | ||
Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells | Q37380645 | ||
mTOR and the control of whole body metabolism | Q37406462 | ||
Activation and clinical significance of the unfolded protein response in breast cancer | Q37424111 | ||
Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: molecular mechanisms and therapeutic perspectives. | Q37603645 | ||
Targeting the endoplasmic reticulum-stress response as an anticancer strategy | Q37616303 | ||
An emerging role of mTOR in lipid biosynthesis. | Q37641438 | ||
Expression of the CD36 homolog (FAT) in fibroblast cells: effects on fatty acid transport | Q37670096 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | breast cancer | Q128581 |
P304 | page(s) | 1509-17 | |
P577 | publication date | 2013-10-01 | |
P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
P1476 | title | Lipid biology of breast cancer | |
P478 | volume | 1831 |
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