Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants

scientific article published on 25 June 2010

Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BRAINRESBULL.2010.06.010
P932PMC publication ID2922476
P698PubMed publication ID20600679
P5875ResearchGate publication ID45091800

P50authorTheodore A. SlotkinQ88773550
Frederic J SeidlerQ88773672
P2093author name stringDoug Lobner
P2860cites workCurrent issues in organophosphate toxicologyQ22337366
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A case for revisiting the safety of pesticides: a closer look at neurodevelopmentQ25256593
The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamateQ28208620
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Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickelQ28395180
Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamilyQ28395997
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Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinonQ30491985
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Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifosQ34292224
Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphatesQ34331472
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Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cellsQ37113546
Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cellsQ37185608
Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamatesQ37658753
Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiationQ38314836
Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell lossQ39633639
Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cellsQ39987295
L-Glutamate in the extracellular space regulates endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cellsQ40578785
Neuronal differentiation in PC12 cells is inhibited by chlorpyrifos and its metabolites: is acetylcholinesterase inhibition the site of action?Q40920286
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Common mechanism of toxicity: a case study of organophosphorus pesticides.Q41728715
Disparate developmental neurotoxicants converge on the cyclic AMP signaling cascade, revealed by transcriptional profiles in vitro and in vivoQ41949474
Unrelated developmental neurotoxicants elicit similar transcriptional profiles for effects on neurotrophic factors and their receptors in an in vitro modelQ42128564
Prenatal exposure to the pesticide dieldrin or the GABA(A) receptor antagonist bicuculline differentially alters expression of GABA(A) receptor subunit mRNAs in fetal rat brainstemQ42542197
In vitro and in vivo induction of heat shock (stress) protein (Hsp) gene expression by selected pesticidesQ42554258
Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical cultureQ43185752
Nickel and strontium distribution in some mouse tissues. Passage through placenta and mammary glandsQ43508863
Hypoxia regulates glutamate metabolism and membrane transport in rat PC12 cellsQ43548239
Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cellsQ43812555
Organophosphorus neuropathy target esterase inhibitors selectively block outgrowth of neurite-like and cell processes in cultured cellsQ44085638
Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degenerationQ44494831
Release and metabolism of dopamine in a clonal line of pheochromocytoma (PC12) cells exposed to fenthionQ45138907
A novel L-glutamate transporter inhibitor reveals endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cellsQ46429804
Gamma-tocopheryl quinone, not alpha-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4.Q46463054
Iptakalim hydrochloride protects cells against neurotoxin-induced glutamate transporter dysfunction in in vitro and in vivo modelsQ46524996
Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifosQ46553074
Copper, manganese, zinc, nickel, cadmium and lead in human foetal tissuesQ48193141
Prenatal exposure to neurotoxicants dieldrin or lindane alters tert-butylbicyclophosphorothionate binding to GABA(A) receptors in fetal rat brainstemQ48463101
Direct actions of anticholinesterases on the neuronal nicotinic acetylcholine receptor channelsQ48592373
Dieldrin toxicosis: fetotoxicosis, tissue concentrations, and microscopic and ultrastructural changes in guinea pigs.Q48789839
Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?Q52167210
The toxicity of organophosphate compounds towards cultured PC12 cells.Q52544690
P433issue1-2
P921main subjectorganophosphateQ411097
P304page(s)76-83
P577publication date2010-06-25
P1433published inBrain Research BulletinQ4955784
P1476titleTranscriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants
P478volume83

Reverse relations

cites work (P2860)
Q35739063Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors
Q28393707Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo
Q28397594Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro
Q34103892Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: Effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells
Q41828857Does mechanism matter? Unrelated neurotoxicants converge on cell cycle and apoptosis during neurodifferentiation

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