Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells

scientific article

Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1289/EHP.8750
P932PMC publication ID1459917
P698PubMed publication ID16675418
P5875ResearchGate publication ID7106308

P50authorTheodore A. SlotkinQ88773550
Frederic J SeidlerQ88773672
P2093author name stringDan Qiao
Ruth R Jameson
P2860cites workDevelopmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signalingQ24810907
Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposureQ24811167
Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cellsQ24813250
Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposureQ24815257
Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target?Q24816964
Measurement of protein using bicinchoninic acidQ26778491
Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9Q28140774
Regulation of the cholinergic gene locus by the repressor element-1 silencing transcription factor/neuron restrictive silencer factor (REST/NRSF)Q28250127
Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout miceQ28590665
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal modelsQ29547388
Organophosphorus pesticides: do they all have the same mechanism of toxicity?Q29615471
Does the developmental neurotoxicity of chlorpyrifos involve glial targets? Macromolecule synthesis, adenylyl cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cellsQ31873230
Developmental cholinotoxicants: nicotine and chlorpyrifosQ33608802
Determination of the reference dose for chlorpyrifos: proceedings of an expert panelQ33701216
Vulnerable processes of nervous system development: a review of markers and methods.Q33905413
Prevalence of fetal exposure to environmental toxins as determined by meconium analysisQ33962016
Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifosQ34292224
Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphatesQ34331472
Accumulation of chlorpyrifos on residential surfaces and toys accessible to childrenQ34936318
Regulation of the differentiation of PC12 pheochromocytoma cellsQ35032923
Age dependence of organophosphate and carbamate neurotoxicity in the postnatal rat: extrapolation to the humanQ35744595
Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targetsQ35862603
Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamatesQ37658753
Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiationQ38314836
Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combinationQ40376841
Neuronal differentiation in PC12 cells is inhibited by chlorpyrifos and its metabolites: is acetylcholinesterase inhibition the site of action?Q40920286
Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cellsQ41016073
Effects of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase, on nucleic acids and proteins in developing rat brain: critical perinatal periods for regional selectivityQ41245643
Mammalian PC-12 cell genetically engineered for human cytochrome P450 2E1 expressionQ41547462
Inhibition of forskolin-stimulated cAMP formation in vitro by paraoxon and chlorpyrifos oxon in cortical slices from neonatal, juvenile, and adult ratsQ42164518
Tyrosine hydroxylase transcription depends primarily on cAMP response element activity, regardless of the type of inducing stimulusQ42458860
Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposureQ42518328
Comparative presynaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathionQ43333139
Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposureQ43625074
Nerve growth factor enhances [3H]nicotine binding to a nicotinic cholinergic receptor on PC 12 cellsQ43690092
Assay of tyrosine hydroxylase by coupled decarboxylation of DOPA formed from 1- 14 C-L-tyrosineQ43723154
The toxicity of chlorpyrifos towards differentiating mouse N2a neuroblastoma cells.Q43744478
Effects of sub-chronic in vivo chlorpyrifos exposure on muscarinic receptors and adenylate cyclase of rat striatumQ43834337
Inhibitors of nitric oxide synthase attenuate nerve growth factor-mediated increases in choline acetyltransferase expression in PC12 cellsQ44028801
Noncholinesterase mechanisms of chlorpyrifos neurotoxicity: altered phosphorylation of Ca2+/cAMP response element binding protein in cultured neuronsQ44078569
Selective effects of insecticides on nigrostriatal dopaminergic nerve pathways.Q44214162
BDNF and CNTF regulate cholinergic properties of sympathetic neurons through independent mechanismsQ44558664
Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifosQ45149272
Effects of repeated oral postnatal exposure to chlorpyrifos on cholinergic neurochemistry in developing ratsQ45221888
Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifosQ46553074
Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal culturesQ46652083
Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathwaysQ48137279
Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: Effects of α-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylaseQ48619378
Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade.Q48673103
Nutritional influences on adrenal chromaffin cell development: comparison with central neurons.Q52249801
Differential modulation of organophosphate-sensitive muscarinic receptors in rat brain by parathion and chlorpyrifos.Q52536101
In vitro effect of chlorpyrifos oxon on muscarinic receptors and adenylate cyclase.Q52536837
Chlorpyrifos, parathion, and their oxons bind to and desensitize a nicotinic acetylcholine receptor: relevance to their toxicities.Q52559630
Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes.Q52575337
Maturation-dependent effects of chlorpyrifos and parathion and their oxygen analogs on acetylcholinesterase and neuronal and glial markers in aggregating brain cell cultures.Q52580193
Protein concentrations in the umbilical cord plasma of premature and mature infants.Q54542219
The binding of physostigmine to human serum albuminQ68170541
Toxicokinetics of methyl parathion and parathion in the dog after intravenous and oral administrationQ71094085
The developmental origins of adult diseaseQ73942742
P433issue5
P921main subjectchlorpyrifosQ414915
P1104number of pages6
P304page(s)667-672
P577publication date2006-05-01
P1433published inEnvironmental Health PerspectivesQ1345904
P1476titleChlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells
P478volume114

Reverse relations

cites work (P2860)
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