Characterization of LMP-1's association with TRAF1, TRAF2, and TRAF3.

scientific article

Characterization of LMP-1's association with TRAF1, TRAF2, and TRAF3. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID191686
P698PubMed publication ID9151858

P2093author name stringM Sandberg
W Hammerschmidt
B Sugden
P2860cites workA novel RING finger protein interacts with the cytoplasmic domain of CD40Q24306382
A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40Q24306620
Involvement of CRAF1, a relative of TRAF, in CD40 signalingQ24306746
Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinomaQ24315735
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathwaysQ24317441
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorQ24318280
Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming proteinQ24599252
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunitQ27860669
CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteinsQ28281794
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor familyQ28307399
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40Q28610812
Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-kappa B activityQ30452167
Cloning and characterization of the latent membrane protein (LMP) of a specific Epstein-Barr virus variant derived from the nasopharyngeal carcinoma in the Taiwanese populationQ30794609
Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elementsQ30990490
Stimulation of NF-kappa B-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virusQ35838888
The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor.Q35841701
Epstein-Barr virus LMP1 induction of the epidermal growth factor receptor is mediated through a TRAF signaling pathway distinct from NF-kappaB activationQ35875444
Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activationQ36564433
Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformationQ36575274
Transformation by the oncogenic latent membrane protein correlates with its rapid turnover, membrane localization, and cytoskeletal associationQ36695348
Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcriptsQ36696963
Processing of the Epstein-Barr virus-encoded latent membrane protein p63/LMPQ36801187
The transforming domain alone of the latent membrane protein of Epstein-Barr virus is toxic to cells when expressed at high levelsQ36827992
Orientation and patching of the latent infection membrane protein encoded by Epstein-Barr virusQ36861507
Posttranslational processing of an Epstein-Barr virus-encoded membrane protein expressed in cells transformed by Epstein-Barr virusQ36885739
Posttranslational processing of the Epstein-Barr virus-encoded p63/LMP proteinQ36889566
Nucleotide sequence of an mRNA transcribed in latent growth-transforming virus infection indicates that it may encode a membrane proteinQ36893502
CD30/TNF receptor-associated factor interaction: NF-kappa B activation and binding specificityQ37360807
All three domains of the Epstein-Barr virus-encoded latent membrane protein LMP-1 are required for transformation of rat-1 fibroblasts.Q40044497
The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain.Q41371042
Upregulation of bcl-2 by the Epstein-Barr virus latent membrane protein LMP1: a B-cell-specific response that is delayed relative to NF-kappa B activation and to induction of cell surface markersQ41447311
Effect of beta-lymphocyte- and NPC-derived EBV-LMP1 gene expression on in vitro growth and differentiation of human epithelial cellsQ41465786
Clonability and tumorigenicity of human epithelial cells expressing the EBV encoded membrane protein LMP1.Q41549956
Morphological transformation of human keratinocytes expressing the LMP gene of Epstein Barr virusQ41733704
Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virusQ41976287
DNA sequence analysis of the EcoRI Dhet fragment of B95-8 Epstein-Barr virus containing the terminal repeat sequencesQ45807158
Transformation of foetal human keukocytes in vitro by filtrates of a human leukaemic cell line containing herpes-like virusQ45814517
TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activationQ48064873
An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.Q53541156
P433issue6
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)4649-4656
P577publication date1997-06-01
P1433published inJournal of VirologyQ1251128
P1476titleCharacterization of LMP-1's association with TRAF1, TRAF2, and TRAF3
P478volume71

Reverse relations

cites work (P2860)
Q40117245A membrane leucine heptad contributes to trafficking, signaling, and transformation by latent membrane protein 1.
Q33759787A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling
Q39606109Activation of TRAF5 and TRAF6 signal cascades negatively regulates the latent replication origin of Epstein-Barr virus through p38 mitogen-activated protein kinase
Q24683297Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein
Q33825713An Epstein-Barr virus that expresses only the first 231 LMP1 amino acids efficiently initiates primary B-lymphocyte growth transformation
Q42937211Analysis of the Epstein-Barr virus (EBV) latent membrane protein 1 (LMP-1) gene and promoter in Hodgkin's disease isolates: selection against EBV variants with mutations in the LMP-1 promoter ATF-1/CREB-1 binding site
Q39645275CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex
Q38782732CD63 Regulates Epstein-Barr Virus LMP1 Exosomal Packaging, Enhancement of Vesicle Production, and Noncanonical NF-κB Signaling
Q33813615Control of cell cycle entry and apoptosis in B lymphocytes infected by Epstein-Barr virus.
Q36369236Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).
Q38869012Epstein - Barr virus Latent Membrane Protein 1 suppresses reporter activity through modulation of promyelocytic leukemia protein-nuclear bodies
Q58803477Epstein-Barr Virus-Associated Malignancies: Roles of Viral Oncoproteins in Carcinogenesis
Q39604074Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways.
Q33887684Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade
Q35291650Epstein-Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors
Q24516975Epstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2
Q33888498Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor
Q39544175Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes
Q34682093Generation and characterization of a novel recombinant antibody against LMP1-TES1 of Epstein-Barr virus isolated by phage display
Q34008771HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2.
Q33642411Hepatitis C virus core protein enhances NF-kappaB signal pathway triggering by lymphotoxin-beta receptor ligand and tumor necrosis factor alpha.
Q37587096High molecular weight complex analysis of Epstein-Barr virus Latent Membrane Protein 1 (LMP-1): structural insights into LMP-1's homo-oligomerization and lipid raft association
Q40595025High physiological levels of LMP1 result in phosphorylation of eIF2 alpha in Epstein-Barr virus-infected cells
Q34479733IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation
Q33786551Interaction of tumor necrosis factor receptor-associated factor signaling proteins with the latent membrane protein 1 PXQXT motif is essential for induction of epidermal growth factor receptor expression
Q33834888Interferon regulatory factor 7 mediates activation of Tap-2 by Epstein-Barr virus latent membrane protein 1.
Q33870488Intracellular signaling molecules activated by Epstein-Barr virus for induction of interferon regulatory factor 7.
Q39685776LMP-1's transmembrane domains encode multiple functions required for LMP-1's efficient signaling
Q33890869LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2
Q35139273LMP1 transmembrane domain 1 and 2 (TM1-2) FWLY mediates intermolecular interactions with TM3-6 to activate NF-kappaB
Q39777437LMP1, a viral relative of the TNF receptor family, signals principally from intracellular compartments
Q35122447Latent infection membrane protein transmembrane FWLY is critical for intermolecular interaction, raft localization, and signaling
Q24682515Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway
Q39593467Latent membrane protein 1 of Epstein-Barr virus inhibits as well as stimulates gene expression
Q33891012Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins
Q34250209Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.
Q37535521Marek's disease is a natural model for lymphomas overexpressing Hodgkin's disease antigen (CD30)
Q33815241Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2.
Q43003742Modification of Cepsilon mRNA expression by EBV-encoded latent membrane protein 1.
Q34225554Molecular virology of Epstein-Barr virus
Q36961875Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor.
Q24300115PRA1 promotes the intracellular trafficking and NF-kappaB signaling of EBV latent membrane protein 1
Q42775424Regulation of CD30 antigen expression and its potential significance for human disease
Q36403897Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes
Q33784729Role of the TRAF binding site and NF-kappaB activation in Epstein-Barr virus latent membrane protein 1-induced cell gene expression
Q33822504Signaling activities of gammaherpesvirus membrane proteins
Q33772240Simian homologues of human herpesvirus 8
Q35634395TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation
Q38359234TRAF1 is a critical regulator of JNK signaling by the TRAF-binding domain of the Epstein-Barr virus-encoded latent infection membrane protein 1 but not CD40.
Q28361340TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1
Q39578471The 30-base-pair deletion in Chinese variants of the Epstein-Barr virus LMP1 gene is not the major effector of functional differences between variant LMP1 genes in human lymphocytes.
Q35076801The Epstein-Barr virus BRRF1 protein, Na, induces lytic infection in a TRAF2- and p53-dependent manner
Q33882153The Epstein-Barr virus and its association with human cancers
Q34327176The Epstein-Barr virus latent membrane protein 1 putative Janus kinase 3 (JAK3) binding domain does not mediate JAK3 association or activation in B-lymphoma or lymphoblastoid cell lines
Q24554457The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation
Q95789811The collagen repeat sequence is a determinant of the degree of herpesvirus saimiri STP transforming activity
Q34089485The expression and function of Epstein-Barr virus encoded latent genes
Q34384112The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor
Q35140197The molecular basis for the generation of Hodgkin and Reed-Sternberg cells in Hodgkin's lymphoma
Q40997583The plasmid replicon of EBV consists of multiple cis-acting elements that facilitate DNA synthesis by the cell and a viral maintenance element
Q39596927The residues between the two transformation effector sites of Epstein-Barr virus latent membrane protein 1 are not critical for B-lymphocyte growth transformation
Q24685892The viral etiology of AIDS-associated malignancies
Q35192167Thermodynamic characterization of the interaction between TRAF2 and tumor necrosis factor receptor peptides by isothermal titration calorimetry
Q39732619Transmembrane domains 1 and 2 of the latent membrane protein 1 of Epstein-Barr virus contain a lipid raft targeting signal and play a critical role in cytostasis
Q37021555Tumor-derived variants of Epstein-Barr virus latent membrane protein 1 induce sustained Erk activation and c-Fos

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