| scholarly article | Q13442814 |
| retracted paper | Q45182324 |
| P356 | DOI | 10.1074/JBC.M604636200 |
| P698 | PubMed publication ID | 16754685 |
| P50 | author | Ersilia Marra | Q40274161 |
| Arnaldo A Arbini | Q43282577 | ||
| P2093 | author name string | Loredana Moro | |
| Margherita Greco | |||
| P2860 | cites work | p53 mediates repression of the BRCA2 promoter and down-regulation of BRCA2 mRNA and protein levels in response to DNA damage | Q44319466 |
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| Beta1 integrins modulate cell adhesion by regulating insulin-like growth factor-II levels in the microenvironment | Q46882692 | ||
| PI3K/Akt signaling regulates p27(kip1) expression via Skp2 in PC3 and DU145 prostate cancer cells, but is not a major factor in p27(kip1) regulation in LNCaP and PC346 cells | Q46902981 | ||
| Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer | Q51992670 | ||
| PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2) | Q73617626 | ||
| Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma Invasion | Q74037504 | ||
| Regulation of Mitogen-activated Protein Kinase Activation by the Cytoplasmic Domain of the α6 Integrin Subunit | Q74263760 | ||
| BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells | Q81656247 | ||
| The BRCA2 gene product functionally interacts with p53 and RAD51 | Q24650406 | ||
| Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression | Q24685645 | ||
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| Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front | Q30989699 | ||
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| Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins. | Q36322254 | ||
| Endothelial cells interact with the core protein of basement membrane perlecan through beta 1 and beta 3 integrins: an adhesion modulated by glycosaminoglycan | Q36532155 | ||
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| Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation | Q40439945 | ||
| Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins. | Q40601873 | ||
| A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells | Q40612662 | ||
| Regulation of beta1C and beta1A integrin expression in prostate carcinoma cells. | Q40621534 | ||
| HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation | Q40767550 | ||
| The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds | Q41226231 | ||
| Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation | Q41237399 | ||
| Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer | Q41454824 | ||
| Mechanisms and consequences of activation of protein kinase B/Akt | Q41751003 | ||
| P433 | issue | 31 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | prostate cancer | Q181257 |
| cell adhesion | Q187640 | ||
| P304 | page(s) | 22100-22107 | |
| P577 | publication date | 2006-06-05 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Up-regulation of Skp2 after prostate cancer cell adhesion to basement membranes results in BRCA2 degradation and cell proliferation | |
| P478 | volume | 281 |
| Q47753583 | Amentoflavone suppresses tumor growth in ovarian cancer by modulating Skp2. |
| Q34095173 | Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. |
| Q33490254 | Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data |
| Q35989467 | Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas |
| Q44993222 | Centrosomal BRCA2 is a target protein of membrane type-1 matrix metalloproteinase (MT1-MMP). |
| Q34452275 | Copy number and targeted mutational analysis reveals novel somatic events in metastatic prostate tumors |
| Q34365216 | Cullins and Cancer |
| Q28388312 | DNA damage response genes and the development of cancer metastasis |
| Q24648025 | Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer |
| Q30278581 | Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis |
| Q112289605 | ER expression associates with poor prognosis in male lung squamous carcinoma after radical resection |
| Q48338119 | ERα, SKP2 and E2F-1 form a feed forward loop driving late ERα targets and G1 cell cycle progression |
| Q91893999 | Identification and structural characterization of deleterious non-synonymous single nucleotide polymorphisms in the human SKP2 gene |
| Q38781756 | Interaction between angiotensin II and relaxin 2 in the progress of growth and spread of prostate cancer cells |
| Q40029092 | Loss of BRCA2 promotes prostate cancer cell invasion through up-regulation of matrix metalloproteinase-9. |
| Q58575520 | Methylsulfonylmethane (organic sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells |
| Q64061295 | MiRNA-7-5p Inhibits the Growth and Migration of Hepatoma Cells via Cross-Species Regulation of S-Phase Kinase-Associated Protein 2 |
| Q39905594 | Mitochondrial DNA depletion in prostate epithelial cells promotes anoikis resistance and invasion through activation of PI3K/Akt2. |
| Q53319625 | Mitochondrial DNA depletion reduces PARP-1 levels and promotes progression of the neoplastic phenotype in prostate carcinoma. |
| Q37614527 | Mitochondrial DNA depletion sensitizes cancer cells to PARP inhibitors by translational and post-translational repression of BRCA2. |
| Q37840759 | NEDD8 Pathways in Cancer, Sine Quibus Non |
| Q37971404 | Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis |
| Q35997223 | Oestrogen-mediated phosphorylation and stabilization of BRCA2 protein in breast |
| Q37678439 | Overexpression of SKP2 Inhibits the Radiation-Induced Bystander Effects of Esophageal Carcinoma |
| Q46304969 | Physcion 8-O-β-glucopyranosideregulates cell cycle, apoptosis, and invasion in glioblastoma cells through modulating Skp2. |
| Q37444091 | RAS promotes tumorigenesis through genomic instability induced by imbalanced expression of Aurora-A and BRCA2 in midbody during cytokinesis. |
| Q24645701 | Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes |
| Q28284368 | Regulation of Skp2 expression and activity and its role in cancer progression |
| Q64243440 | SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination |
| Q38987920 | Silencing of BRCA2 decreases anoikis and its heterologous expression sensitizes yeast cells to acetic acid-induced programmed cell death |
| Q40096464 | Skp2 inhibits osteogenesis by promoting ubiquitin-proteasome degradation of Runx2. |
| Q34838226 | Skp2 overexpression is associated with loss of BRCA2 protein in human prostate cancer |
| Q24625558 | Skp2: A novel potential therapeutic target for prostate cancer |
| Q92390159 | Targeting SCF E3 Ligases for Cancer Therapies |
| Q89515865 | The Skp2 Pathway: A Critical Target for Cancer Therapy |
| Q38113016 | The role of BRCA1 and BRCA2 in prostate cancer |
| Q34227747 | The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth |
| Q26782159 | The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma |
| Q37767875 | The ubiquitin-proteasome system in prostate cancer and its transition to castration resistance |
| Q42362115 | p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance |
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