| scholarly article | Q13442814 |
| P50 | author | Markus Grompe | Q28967735 |
| P2093 | author name string | Andreas Rothfuss | |
| P2860 | cites work | UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization | Q24531288 |
| Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses | Q24677973 | ||
| Megabase chromatin domains involved in DNA double-strand breaks in vivo | Q24680284 | ||
| DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
| Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139 | Q28139691 | ||
| A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage | Q28144576 | ||
| The Fanconi anaemia/BRCA pathway | Q28201371 | ||
| Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress | Q28201846 | ||
| S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51 | Q28202527 | ||
| Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway | Q28203777 | ||
| Induction of DNA replication-mediated double strand breaks by psoralen DNA interstrand cross-links | Q44243364 | ||
| Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents. | Q52828715 | ||
| In vivo genotoxicity of dichloroacetic acid: evaluation with the mouse peripheral blood micronucleus assay and the single cell gel assay. | Q53458688 | ||
| Deficiency in BRCA2 leads to increase in non-conservative homologous recombination. | Q53963846 | ||
| Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families | Q64388665 | ||
| Microgel electrophoresis: sensitivity, mechanisms, and DNA electrostretching | Q64389259 | ||
| A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents | Q68664547 | ||
| Differential introduction and repair of psoralen photoadducts to DNA in specific human genes | Q70154003 | ||
| Elevated homologous recombination activity in fanconi anemia fibroblasts | Q73674707 | ||
| The comet assay (single-cell gel test). A sensitive genotoxicity test for the detection of DNA damage and repair | Q78114381 | ||
| A novel ubiquitin ligase is deficient in Fanconi anemia | Q28206919 | ||
| Histone H2A variants H2AX and H2AZ | Q28207014 | ||
| Biallelic inactivation of BRCA2 in Fanconi anemia | Q29616130 | ||
| BRCA2 is required for homology-directed repair of chromosomal breaks | Q29618799 | ||
| Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair | Q30648450 | ||
| DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts | Q30845806 | ||
| Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease. | Q33908401 | ||
| Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences | Q34081887 | ||
| DNA polymerase stalling, sister chromatid recombination and the BRCA genes | Q34130589 | ||
| hMutSbeta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro | Q34276816 | ||
| Repair of DNA interstrand cross-links | Q34343361 | ||
| Fanconi anemia and DNA repair | Q34416703 | ||
| Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance. | Q34571928 | ||
| The comet assay. An overview of techniques | Q34695068 | ||
| Repair of DNA Containing Interstrand Crosslinks in Escherichia coli: Sequential Excision and Recombination | Q35100710 | ||
| Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells | Q35161876 | ||
| Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation. | Q35195073 | ||
| The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: comparison of wild-type and repair-deficient strains | Q36286355 | ||
| Initiation of DNA interstrand cross-link repair in humans: the nucleotide excision repair system makes dual incisions 5' to the cross-linked base and removes a 22- to 28-nucleotide-long damage-free strand | Q36573759 | ||
| Angelicins, angular analogs of psoralens: chemistry, photochemical, photobiological and phototherapeutic properties | Q37060523 | ||
| Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells | Q39456389 | ||
| DNA replication is required To elicit cellular responses to psoralen-induced DNA interstrand cross-links. | Q39456549 | ||
| DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coli | Q39495577 | ||
| DNA adducts of medicinal drugs: some selected examples | Q39591849 | ||
| Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin | Q39688114 | ||
| Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics | Q40484333 | ||
| The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase | Q40762324 | ||
| Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation | Q40798697 | ||
| Fanconi anemia, complementation group A, cells are defective in ability to produce incisions at sites of psoralen interstrand cross-links | Q40888588 | ||
| Detection of crosslinks with the comet assay in relationship to genotoxicity and cytotoxicity | Q40958541 | ||
| DNA adducts from chemotherapeutic agents | Q41090650 | ||
| Sensitivity of CHO mutant cell lines with specific defects in nucleotide excision repair to different anti-cancer agents. | Q41192356 | ||
| Molecular biology of Fanconi anemia: implications for diagnosis and therapy | Q41591099 | ||
| Repair of psoralen-induced cross-links and monoadducts in normal and repair-deficient human fibroblasts | Q43777963 | ||
| Processing of psoralen adducts in an active human gene: repair and replication of DNA containing monoadducts and interstrand cross-links | Q43794638 | ||
| S. cerevisiae has three pathways for DNA interstrand crosslink repair | Q43819402 | ||
| Attenuation of the formation of DNA-repair foci containing RAD51 in Fanconi anaemia | Q44064001 | ||
| Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody | Q44140576 | ||
| DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein | Q44159127 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 123-134 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway | |
| P478 | volume | 24 |
| Q42709830 | 3-Methyladenine DNA glycosylase is important for cellular resistance to psoralen interstrand cross-links. |
| Q48014596 | A Boolean network model of the FA/BRCA pathway. |
| Q40514077 | A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint |
| Q34619732 | ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency |
| Q39941293 | ATR couples FANCD2 monoubiquitination to the DNA-damage response |
| Q92341124 | Acid-specific formaldehyde donor is a potential, dual targeting cancer chemotherapeutic/chemo preventive drug for FANC/BRCA-mutant cancer |
| Q46781831 | An in vivo analysis of MMC-induced DNA damage and its repair |
| Q39958586 | BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks |
| Q42016124 | BRCA1 Forms a Functional Complex with γ-H2AX as a Late Response to Genotoxic Stress |
| Q41848878 | BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells. |
| Q90284585 | Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment |
| Q36370912 | CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene |
| Q37661508 | Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention |
| Q35904230 | Celastrol induces proteasomal degradation of FANCD2 to sensitize lung cancer cells to DNA crosslinking agents. |
| Q33755415 | Cellular Repair of DNA-DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane |
| Q28252640 | Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights |
| Q41537227 | Cho Endonuclease Functions during DNA Interstrand Cross-Link Repair in Escherichia coli |
| Q36813011 | Chromatin as a target for the DNA-binding anticancer drugs. |
| Q34623681 | Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links |
| Q24303573 | CtIP is required to initiate replication-dependent interstrand crosslink repair |
| Q24559729 | DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation |
| Q37487925 | DNA interstrand crosslink repair in mammalian cells |
| Q33669915 | DNA interstrand crosslink repair in mammalian cells: step by step |
| Q36002324 | DNA interstrand crosslinks: natural and drug-induced DNA adducts that induce unique cellular responses |
| Q40037588 | DNA polymerase eta reduces the gamma-H2AX response to psoralen interstrand crosslinks in human cells |
| Q35996723 | DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents |
| Q44948936 | DNA repair defects channel interstrand DNA cross-links into alternate recombinational and error-prone repair pathways |
| Q35857071 | DNA structure-induced recruitment and activation of the Fanconi anemia pathway protein FANCD2 |
| Q81600956 | DUBing down a tumour suppressor |
| Q35028557 | Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein. |
| Q24337605 | Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents |
| Q39099549 | Detection of DNA double-strand breaks by pulsed-field gel electrophoresis |
| Q53213187 | Differential roles for Chk1 and FANCD2 in ATR-mediated signalling for psoralen photoactivation-induced senescence. |
| Q33648841 | Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links |
| Q33925085 | Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis |
| Q35728414 | Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility |
| Q36953770 | ERCC1 is required for FANCD2 focus formation |
| Q38699009 | Effects of single-dose atorvastatin on interleukin-6, interferon gamma, and myocardial no-reflow in a rabbit model of acute myocardial infarction and reperfusion |
| Q46957793 | Enhanced repair of DNA interstrand crosslinks in S phase |
| Q41010245 | Evaluation of concentration and storage effects of mitomycin C in the diagnosis of Fanconi anemia among idiopatic aplastic anemia patients |
| Q24316458 | Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links |
| Q64240710 | Expression and prognostic significance of Fanconi anemia group D2 protein and breast cancer type 1 susceptibility protein in familial and sporadic breast cancer |
| Q28756695 | FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: activation is not required for repair of Cr(VI)-induced DSBs |
| Q39847548 | FANCD2-deficient human fibroblasts are hypersensitive to ionising radiation at oxygen concentrations of 0% and 3% but not under normoxic conditions |
| Q30434487 | FANCG is phosphorylated at serines 383 and 387 during mitosis |
| Q24312445 | FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL |
| Q37865169 | Fanconi anaemia: from a monogenic disease to sporadic cancer |
| Q42548726 | Fanconi anemia proteins and endogenous stresses |
| Q34301932 | Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks |
| Q37069628 | Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy |
| Q39448511 | Filamin-A as a marker and target for DNA damage based cancer therapy. |
| Q37431184 | Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif |
| Q34406515 | Gene silencing of FANCF potentiates the sensitivity to mitoxantrone through activation of JNK and p38 signal pathways in breast cancer cells |
| Q47912248 | Ginsenosides synergize with mitomycin C in combating human non-small cell lung cancer by repressing Rad51-mediated DNA repair |
| Q29618825 | Hallmarks of 'BRCAness' in sporadic cancers |
| Q28509626 | Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability |
| Q64388688 | Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis |
| Q36019436 | How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recovery |
| Q34356341 | Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation |
| Q24337575 | Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2 |
| Q39943294 | Impaired removal of DNA interstrand cross-link in Nijmegen breakage syndrome and Fanconi anemia, but not in BRCA-defective group |
| Q34026606 | Initiation of DNA interstrand cross-link repair in mammalian cells |
| Q33768588 | Ionizing radiation-dependent gamma-H2AX focus formation requires ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3-related |
| Q33290506 | Is the natural PCDD/PCDF mixture toxic for human placental JEG-3 cell line? The action of the toxicants on hormonal profile, CYP1A1 activity, DNA damage and cell apoptosis. |
| Q87603422 | K63-linked ubiquitination of FANCG is required for its association with the Rap80-BRCA1 complex to modulate homologous recombination repair of DNA interstand crosslinks |
| Q43167066 | KSR1 is required for cell cycle reinitiation following DNA damage |
| Q64389179 | Limited Capacity or Involvement of Excision Repair, Double-Strand Breaks, or Translesion Synthesis for Psoralen Cross-Link Repair in |
| Q39945403 | Loss of homologous recombination or non-homologous end-joining leads to radial formation following DNA interstrand crosslink damage |
| Q36514229 | MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair |
| Q24315682 | MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair |
| Q26865523 | Mechanism and regulation of incisions during DNA interstrand cross-link repair |
| Q34832238 | Mechanism of replication-coupled DNA interstrand crosslink repair |
| Q26746868 | Mechanisms of interstrand DNA crosslink repair and human disorders |
| Q30438241 | Molecular pathogenesis of Fanconi anemia |
| Q39553171 | Monoubiquitinated Fanconi anemia D2 (FANCD2-Ub) is required for BCR-ABL1 kinase-induced leukemogenesis |
| Q28288789 | Multiple roles of ERCC1-XPF in mammalian interstrand crosslink repair |
| Q39700581 | Nek1 silencing slows down DNA repair and blocks DNA damage-induced cell cycle arrest |
| Q38220992 | Nuclease delivery: versatile functions of SLX4/FANCP in genome maintenance |
| Q36226849 | Nucleotide excision repair |
| Q26992194 | Pathways for repairing and tolerating the spectrum of oxidative DNA lesions |
| Q33835134 | Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity |
| Q46897838 | Processing of a psoralen DNA interstrand cross-link by XPF-ERCC1 complex in vitro |
| Q38052100 | REV1 and DNA polymerase zeta in DNA interstrand crosslink repair |
| Q37600026 | RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells |
| Q36457732 | Regulation of DNA repair by ubiquitylation |
| Q36512615 | Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4. |
| Q37775586 | Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle |
| Q33493863 | Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cells |
| Q42259807 | Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase |
| Q37775588 | Role of homologous recombination in DNA interstrand crosslink repair |
| Q36687824 | Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. |
| Q93180057 | SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair |
| Q42260305 | Senescence of human fibroblasts after psoralen photoactivation is mediated by ATR kinase and persistent DNA damage foci at telomeres |
| Q49473342 | Splice variants of the endonucleases XPF and XPG contain residual DNA repair capabilities and could be a valuable tool for personalized medicine |
| Q33862088 | Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer |
| Q33855938 | Taking a Bad Turn: Compromised DNA Damage Response in Leukemia |
| Q35902345 | Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma |
| Q52646141 | The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. |
| Q40440435 | The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells |
| Q40183559 | The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents |
| Q39986749 | The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly |
| Q37356265 | The Fanconi anemia protein interaction network: casting a wide net. |
| Q36543285 | The Fanconi anemia/BRCA pathway: a coordinator of cross-link repair |
| Q37397475 | The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair |
| Q34743439 | The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair |
| Q53775795 | The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells. |
| Q24297351 | The role of BRCA2 in replication-coupled DNA interstrand cross-link repair in vitro |
| Q33347783 | The role of the Fanconi anemia network in the response to DNA replication stress |
| Q28592473 | The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks |
| Q38774142 | The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks |
| Q38810986 | Trans-dichlorooxovandium (IV) complex as a novel photoinducible DNA interstrand crosslinker for cancer therapy. |
| Q24816234 | Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways |
| Q40020039 | Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis |
| Q34132691 | Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy |
| Q64067901 | WIP1 Contributes to the Adaptation of Fanconi Anemia Cells to DNA Damage as Determined by the Regulatory Network of the Fanconi Anemia and Checkpoint Recovery Pathways |
| Q36854964 | WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks |
| Q38619026 | What is the DNA repair defect underlying Fanconi anemia? |
| Q24329172 | gamma-H2AX formation in response to interstrand crosslinks requires XPF in human cells |
| Q36280699 | p21 promotes error-free replication-coupled DNA double-strand break repair |
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