| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M206459200 |
| P698 | PubMed publication ID | 12194981 |
| P2093 | author name string | Heather Sadlish | |
| Frederick M R Williams | |||
| Wayne F Flintoff | |||
| P2860 | cites work | Functional interactions between arginine-133 and aspartate-88 in the human reduced folate carrier: evidence for a charge-pair association | Q28346424 |
| Topological and functional analysis of the human reduced folate carrier by hemagglutinin epitope insertion | Q28609909 | ||
| Folic acid: nutritional biochemistry, molecular biology, and role in disease processes | Q33918970 | ||
| Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line | Q38291140 | ||
| Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function | Q40732580 | ||
| Mutations in the reduced-folate carrier affect protein localization and stability | Q40891908 | ||
| Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier | Q40921250 | ||
| A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate | Q41045869 | ||
| Cytoplasmic domains of the reduced folate carrier are essential for trafficking, but not function | Q41881973 | ||
| Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells | Q42803378 | ||
| Helix proximity in OxlT, the oalate:formate antiporter of oxalobacter formigenes. Cross-linking between TM2 and TM11. | Q43678727 | ||
| Conformational changes that occur during M3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy | Q43792236 | ||
| Proximity of periplasmic loops in the lactose permease of Escherichia coli determined by site-directed cross-linking. | Q45979138 | ||
| Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate | Q46061580 | ||
| Isolation of high-molecular-weight DNA from mammalian cells | Q47366140 | ||
| A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function. | Q47828197 | ||
| A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter w | Q48040147 | ||
| Down-regulation of reduced folate carrier gene (RFC1) expression after exposure to methotrexate in ZR-75-1 breast cancer cells. | Q54022612 | ||
| Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier. | Q54100948 | ||
| A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance. | Q54118067 | ||
| Genetic characterization of methotrexate-resistant chinese hamster ovary cells | Q68294720 | ||
| Mutant Chinese hamster ovary cells with defective methotrexate uptake are distinguishable by reversion analysis | Q69735636 | ||
| Transport of methotrexate in Chinese hamster ovary cells: a mutant defective in methotrexate uptake and cell binding | Q71758035 | ||
| Chromosomal localization of the reduced folate transporter gene (SLC19A1) in Chinese hamster ovary cells | Q72014119 | ||
| P433 | issue | 44 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | folic acid | Q127060 |
| P304 | page(s) | 42105-42112 | |
| P577 | publication date | 2002-08-22 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Functional role of arginine 373 in substrate translocation by the reduced folate carrier | |
| P478 | volume | 277 |
| Q38354623 | Characterization of a cysteine-less human reduced folate carrier: localization of a substrate-binding domain by cysteine-scanning mutagenesis and cysteine accessibility methods |
| Q34444820 | Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods |
| Q35173884 | Membrane transport of folates |
| Q33770110 | Methods to evaluate the effect of ethanol on the folate analogue: fluorescein methotrexate uptake in human proximal tubular cells |
| Q37075336 | Oligomeric structure of the human reduced folate carrier: identification of homo-oligomers and dominant-negative effects on carrier expression and function |
| Q38353186 | Residues 45 and 404 in the murine reduced folate carrier may interact to alter carrier binding and mobility |
| Q40520881 | Restoration of transport activity by co-expression of human reduced folate carrier half-molecules in transport-impaired K562 cells: localization of a substrate binding domain to transmembrane domains 7-12. |
| Q37249995 | Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibition |
| Q90069567 | SLC19A1 transports immunoreactive cyclic dinucleotides |
| Q34657202 | Structure and function of the reduced folate carrier a paradigm of a major facilitator superfamily mammalian nutrient transporter |
| Q37663377 | The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer |
| Q34221144 | The region between transmembrane domains 1 and 2 of the reduced folate carrier forms part of the substrate-binding pocket |
| Q40241191 | Transmembrane domains 4, 5, 7, 8, and 10 of the human reduced folate carrier are important structural or functional components of the transmembrane channel for folate substrates |
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