scholarly article | Q13442814 |
P50 | author | Ronald Swanstrom | Q62641484 |
P2093 | author name string | Celia A Schiffer | |
Sook-Kyung Lee | |||
Debra Ragland | |||
Ellen Nalivaika | |||
Marc Potempa | |||
P2860 | cites work | Regulation of intracellular pH by human peripheral blood lymphocytes as measured by 19F NMR | Q24628519 |
Active human immunodeficiency virus protease is required for viral infectivity | Q24647696 | ||
HIV-1 protease and reverse transcriptase control the architecture of their nucleocapsid partner | Q27302871 | ||
How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease | Q27626817 | ||
Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes | Q27638967 | ||
Structural Evidence for Effectiveness of Darunavir and Two Related Antiviral Inhibitors against HIV-2 Protease | Q27652399 | ||
Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus | Q27666141 | ||
Protein conformational dynamics in the mechanism of HIV-1 protease catalysis | Q27676129 | ||
Terminal Interface Conformations Modulate Dimer Stability Prior to Amino Terminal Autoprocessing of HIV-1 Protease | Q27676717 | ||
Structural, kinetic, and thermodynamic studies of specificity designed HIV-1 protease | Q27678853 | ||
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1 | Q27702268 | ||
Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution | Q27703994 | ||
Crystal structure of a tethered dimer of HIV-1 proteinase complexed with an inhibitor | Q27729870 | ||
Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases | Q27730719 | ||
Crystal structure of dimeric HIV-1 capsid protein | Q27733334 | ||
Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease | Q33215093 | ||
A stiffness switch in human immunodeficiency virus | Q33266091 | ||
Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease. | Q33559311 | ||
Revealing the dimer dissociation and existence of a folded monomer of the mature HIV-2 protease | Q33650307 | ||
Opposing mechanisms involving RNA and lipids regulate HIV-1 Gag membrane binding through the highly basic region of the matrix domain | Q33667586 | ||
The capsid-spacer peptide 1 Gag processing intermediate is a dominant-negative inhibitor of HIV-1 maturation | Q33727091 | ||
Stability and activity of human immunodeficiency virus protease: comparison of the natural dimer with a homologous, single-chain tethered dimer | Q33924472 | ||
An allosteric modulator of HIV-1 protease shows equipotent inhibition of wild-type and drug-resistant proteases | Q34061377 | ||
Comparison of the HIV-1 and HIV-2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins | Q34098983 | ||
Redundant roles for nucleocapsid and matrix RNA-binding sequences in human immunodeficiency virus type 1 assembly | Q34123957 | ||
A structural model for the retroviral proteases. | Q34173510 | ||
Sequence-specific interaction between HIV-1 matrix protein and viral genomic RNA revealed by in vitro genetic selection | Q34363543 | ||
Curling of flap tips in HIV-1 protease as a mechanism for substrate entry and tolerance of drug resistance | Q34513432 | ||
HIV-1 matrix protein binding to RNA. | Q35114688 | ||
Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy. | Q35212464 | ||
Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114 | Q35608637 | ||
Determinants of the human immunodeficiency virus type 1 p15NC-RNA interaction that affect enhanced cleavage by the viral protease. | Q35889311 | ||
Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease | Q35921690 | ||
G-quartets direct assembly of HIV-1 nucleocapsid protein along single-stranded DNA. | Q36118837 | ||
Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: IV. viral proteinase slides along DNA to locate and process its substrates | Q36543835 | ||
Cleavage of p15 protein in vitro by human immunodeficiency virus type 1 protease is RNA dependent | Q36635813 | ||
The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency. | Q36636632 | ||
Functional domains of the capsid protein of human immunodeficiency virus type 1 | Q36638060 | ||
Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations | Q36639010 | ||
Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles. | Q36650046 | ||
Catalytic contribution of flap-substrate hydrogen bonds in "HIV-1 protease" explored by chemical synthesis | Q36718166 | ||
Overexpression of the gag-pol precursor from human immunodeficiency virus type 1 proviral genomes results in efficient proteolytic processing in the absence of virion production | Q36797953 | ||
Suboptimal inhibition of protease activity in human immunodeficiency virus type 1: effects on virion morphogenesis and RNA maturation | Q36958798 | ||
The poly dA helix: a new structural motif for high performance DNA-based molecular switches. | Q37199522 | ||
HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity. | Q37447762 | ||
Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity | Q37480211 | ||
??? | Q57904706 | ||
The cell biology of HIV-1 virion genesis | Q37520101 | ||
tRNA stabilization by modified nucleotides | Q37748755 | ||
Human adenovirus proteinase: DNA binding and stimulation of proteinase activity by DNA. | Q38295300 | ||
Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites. | Q39579012 | ||
In vitro selection of RNAs that bind to the human immunodeficiency virus type-1 gag polyprotein | Q39720527 | ||
The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions. | Q40042979 | ||
Mutagenesis of protease cleavage sites in the human immunodeficiency virus type 1 gag polyprotein | Q40059062 | ||
Mutant murine leukemia virus Gag proteins lacking proline at the N-terminus of the capsid domain block infectivity in virions containing wild-type Gag. | Q40326740 | ||
Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor | Q40446011 | ||
Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition. | Q40792083 | ||
In vivo processing of Pr160gag-pol from human immunodeficiency virus type 1 (HIV) in acutely infected, cultured human T-lymphocytes | Q41258387 | ||
Initial cleavage of the human immunodeficiency virus type 1 GagPol precursor by its activated protease occurs by an intramolecular mechanism | Q41275889 | ||
Ordered processing of the human immunodeficiency virus type 1 GagPol precursor is influenced by the context of the embedded viral protease | Q41997191 | ||
Regulation of foamy virus protease activity by viral RNA: a novel and unique mechanism among retroviruses | Q42089507 | ||
A strongly transdominant mutation in the human immunodeficiency virus type 1 gag gene defines an Achilles heel in the virus life cycle | Q42546287 | ||
Recombinant HIV2 protease processes HIV1 Pr53gag and analogous junction peptides in vitro. | Q42633395 | ||
Dynamics of preferential substrate recognition in HIV-1 protease: redefining the substrate envelope | Q42825525 | ||
The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate | Q43041225 | ||
Effectors of HIV-1 protease peptidolytic activity | Q43733400 | ||
An ordered single-stranded structure for polyadenylic acid in denaturing solvents. An X-ray fiber diffraction and model building study | Q44577848 | ||
Viral DNA and a viral peptide can act as cofactors of adenovirus virion proteinase activity | Q44639077 | ||
Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation | Q44926187 | ||
Influence of flanking sequences on the dimer stability of human immunodeficiency virus type 1 protease | Q45767677 | ||
Proteolytic processing of HIV-1 protease precursor, kinetics and mechanism | Q47940296 | ||
Direct measurements of base stacking interactions in DNA by single-molecule atomic-force spectroscopy. | Q50942592 | ||
Dissociation and association of the HIV-1 protease dimer subunits: equilibria and rates. | Q52383123 | ||
Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid | Q54693321 | ||
Comparative analysis of the sequences and structures of HIV-1 and HIV-2 proteases | Q68051379 | ||
Cleavage of HIV-1 gag polyprotein synthesized in vitro: sequential cleavage by the viral protease | Q69564852 | ||
Proton magnetic resonance study of polydeoxyriboadenylic acid | Q70621431 | ||
Nucleic acid binding properties of recombinant Zn2 HIV-1 nucleocapsid protein are modulated by COOH-terminal processing | Q72165705 | ||
Wild-type and mutant HIV type 1 nucleocapsid proteins increase the proportion of long cDNA transcripts by viral reverse transcriptase | Q73307812 | ||
The i-motif in nucleic acids | Q73889028 | ||
The molecular structure of polyadenylic acid | Q78992461 | ||
Dynamics of "flap" structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy | Q83131659 | ||
Dynamic flaps in HIV-1 protease adopt unique ordering at different stages in the catalytic cycle | Q83782525 | ||
P4510 | describes a project that uses | ImageQuant | Q112270642 |
P433 | issue | 14 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2360-2378 | |
P577 | publication date | 2015-05-15 | |
P1433 | published in | Journal of Molecular Biology | Q925779 |
P1476 | title | A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro | |
P478 | volume | 427 |
Q51740197 | An RNA-binding compound that stabilizes the HIV-1 gRNA packaging signal structure and specifically blocks HIV-1 RNA encapsidation. |
Q26739673 | Coordination of Genomic RNA Packaging with Viral Assembly in HIV-1 |
Q59361002 | Effect of tRNA on the Maturation of HIV-1 Reverse Transcriptase |
Q61445564 | Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment |
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