| scholarly article | Q13442814 |
| P50 | author | Jens B. Nielsen | Q16733372 |
| Irina Borodina | Q41775415 | ||
| Preben Krabben | Q59550286 | ||
| P2860 | cites work | An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR) | Q21194867 |
| Metabolic flux balance analysis and the in silico analysis of Escherichia coli K-12 gene deletions | Q21284379 | ||
| Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network | Q24561581 | ||
| The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities | Q24655269 | ||
| Sequence, transcriptional, and functional analyses of the valine (branched-chain amino acid) dehydrogenase gene of Streptomyces coelicolor | Q24670595 | ||
| A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases | Q24800167 | ||
| Toward metabolic phenomics: analysis of genomic data using flux balances | Q28198143 | ||
| Metabolic network structure determines key aspects of functionality and regulation | Q28214885 | ||
| The Pathway Tools software | Q28217270 | ||
| Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways inStreptomyces coelicolorusing DNA microarrays | Q28365649 | ||
| Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis | Q28486584 | ||
| Identification of a short (C15) chain Z-isoprenyl diphosphate synthase and a homologous long (C50) chain isoprenyl diphosphate synthase in Mycobacterium tuberculosis | Q28487062 | ||
| Phosphatidylinositol is an essential phospholipid of mycobacteria | Q28487431 | ||
| Nitrogen metabolism in Streptomyces coelicolor A3(2): modification of glutamine synthetase I by an adenylyltransferase | Q28504060 | ||
| Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) | Q29547307 | ||
| Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization | Q29616020 | ||
| Integrated genomic and proteomic analyses of a systematically perturbed metabolic network | Q29616021 | ||
| In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data | Q29618471 | ||
| Defining transcription modules using large-scale gene expression data | Q30916115 | ||
| Integrating high-throughput and computational data elucidates bacterial networks | Q30928624 | ||
| Primary and secondary metabolism, and post-translational protein modifications, as portrayed by proteomic analysis of Streptomyces coelicolor | Q31117973 | ||
| Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts | Q32140802 | ||
| Recovery of respiration following the SOS response of Escherichia coli requires RecA-mediated induction of 2-keto-4-hydroxyglutarate aldolase | Q33724901 | ||
| Forty years of genetics with Streptomyces: from in vivo through in vitro to in silico | Q33750125 | ||
| Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2). | Q33911476 | ||
| Primary metabolism and its control in streptomycetes: a most unusual group of bacteria | Q33977149 | ||
| Purification of an inducible L-valine dehydrogenase of Streptomyces coelicolor A3(2). | Q34318200 | ||
| Metabolomics and systems biology: making sense of the soup | Q34548620 | ||
| The respiratory chain of Corynebacterium glutamicum. | Q35209181 | ||
| Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model | Q35574107 | ||
| Cloning and characterization of a gene (msdA) encoding methylmalonic acid semialdehyde dehydrogenase from Streptomyces coelicolor | Q35601258 | ||
| Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network | Q37087145 | ||
| The malEFG gene cluster of Streptomyces coelicolor A3(2): characterization, disruption and transcriptional analysis | Q38345782 | ||
| The Folate Branch of the Methionine Biosynthesis Pathway in Streptomyces lividans : Disruption of the 5,10-Methylenetetrahydrofolate Reductase Gene Leads to Methionine Auxotrophy | Q39565140 | ||
| Genome-scale metabolic model of Helicobacter pylori 26695. | Q39679903 | ||
| Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110. | Q39916365 | ||
| Utilization of energy for growth and maintenance in continuous and batch cultures of microorganisms. A reevaluation of the method for the determination of ATP production by measuring molar growth yields | Q39926656 | ||
| 13C nuclear magnetic resonance and gas chromatography-mass spectrometry studies of carbon metabolism in the actinomycin D producer Streptomyces parvulus by use of 13C-labeled precursors | Q39958277 | ||
| Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis | Q41724916 | ||
| The expression of the trpD, trpC and trpBA genes of Streptomyces coelicolor A3(2) is regulated by growth rate and growth phase but not by feedback repression | Q42603221 | ||
| Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis | Q43906563 | ||
| Carbon flux distribution in antibiotic-producing chemostat cultures of Streptomyces lividans | Q43992568 | ||
| A theoretical analysis of the biosynthesis of actinorhodin in a hyper-producing Streptomyces lividansstrain cultivated on various carbon sources | Q44001049 | ||
| Proteomic studies of diauxic lag in the differentiating prokaryote Streptomyces coelicolor reveal a regulatory network of stress-induced proteins and central metabolic enzymes | Q44465865 | ||
| Precursor-Directed polyketide biosynthesis in Escherichia coli | Q44614126 | ||
| 6-Deoxyerythronolide B analogue production in Escherichia coli through metabolic pathway engineering. | Q44670410 | ||
| Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast | Q47363112 | ||
| Negative feedback regulation of dnaK, clpB and lon expression by the DnaK chaperone machine in Streptomyces coelicolor, identified by transcriptome and in vivo DnaK-depletion analysis. | Q47441545 | ||
| Large-scale evaluation of in silico gene deletions in Saccharomyces cerevisiae | Q47609184 | ||
| A sigmaB-like factor responsible for carotenoid biosynthesis in Streptomyces griseus | Q48379926 | ||
| DNA rearrangements associated with instability of an arginine gene in Streptomyces coelicolor A3(2). | Q54414460 | ||
| Menaquinone composition in the classification and identification of aerobic actinomycetes | Q68384602 | ||
| Ubiquinone and menaquinone in bacteria: a comparative study of some bacterial respiratory systems | Q68563296 | ||
| Malyl-CoA formation in the NAD-, CoASH-, and alpha-ketoglutarate dehydrogenase-dependent oxidation of 2-keto-4-hydroxyglutarate. Possible coupled role of this reaction with 2-keto-4-hydroxyglutarate aldolase activity in a pyruvate-catalyzed cyclic o | Q70375063 | ||
| Growth rate control of protein and nucleic acid content in Streptomyces coelicolor A3(2) and Escherichia coli B/r | Q71407337 | ||
| Glucose utilization by Streptomyces griseus | Q73535376 | ||
| Production of actinorhodin by Streptomyces coelicolor A3(2) grown in chemostat culture | Q81660327 | ||
| P433 | issue | 6 | |
| P921 | main subject | Streptomyces coelicolor | Q2355919 |
| P304 | page(s) | 820-829 | |
| P577 | publication date | 2005-06-01 | |
| P1433 | published in | Genome Research | Q5533485 |
| P1476 | title | Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism | |
| P478 | volume | 15 |
| Q42183084 | 5′-Methylthioadenosine Nucleosidase Is Implicated in Playing a Key Role in a Modified Futalosine Pathway for Menaquinone Biosynthesis in Campylobacter jejuni |
| Q37285186 | A eukaryote-like cardiolipin synthase is present in Streptomyces coelicolor and in most actinobacteria. |
| Q24603373 | A protocol for generating a high-quality genome-scale metabolic reconstruction |
| Q35178614 | Accomplishments in genome-scale in silico modeling for industrial and medical biotechnology |
| Q33910420 | Acorn: a grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks via a web interface |
| Q110391622 | Actinobacteria in natural products research: Progress and prospects |
| Q38170294 | Activating secondary metabolism with stress and chemicals |
| Q34831016 | An alternative menaquinone biosynthetic pathway operating in microorganisms |
| Q88173397 | Analysis of metabolic networks of Streptomyces leeuwenhoekii C34 by means of a genome scale model: Prediction of modifications that enhance the production of specialized metabolites |
| Q35690948 | Anti-Methicillin Resistant Staphylococcus aureus Activity and Optimal Culture Condition of Streptomyces sp. SUK 25 |
| Q46497350 | Antibiotic overproduction in Streptomyces coelicolor A3 2 mediated by phosphofructokinase deletion |
| Q87423423 | Application of a combined approach involving classical random mutagenesis and metabolic engineering to enhance FK506 production in Streptomyces sp. RM7011 |
| Q29031028 | Applications of genome-scale metabolic reconstructions |
| Q37971381 | Applications of system-level models of metabolism for analysis of bacterial physiology and identification of new drug targets |
| Q33849390 | Assessment of the Potential Role of Streptomyces in Cave Moonmilk Formation. |
| Q42739003 | BioMet Toolbox: genome-wide analysis of metabolism |
| Q57014364 | Bioinformatics for Metabolomics |
| Q35078339 | Carbon-flux distribution within Streptomyces coelicolor metabolism: a comparison between the actinorhodin-producing strain M145 and its non-producing derivative M1146. |
| Q42631209 | Cardiolipin synthase is required for Streptomyces coelicolor morphogenesis |
| Q64166988 | Chapter 5 Applying the Genetics of Secondary Metabolism in Model Actinomycetes to the Discovery of New Antibiotics |
| Q41771276 | Characterization of recombinant UDP- and ADP-glucose pyrophosphorylases and glycogen synthase to elucidate glucose-1-phosphate partitioning into oligo- and polysaccharides in Streptomyces coelicolor. |
| Q46686273 | Characterization of the chromosomal integration of Saccharopolyspora plasmid pCM32 and its application to improve production of spinosyn in Saccharopolyspora spinosa |
| Q33682086 | Characterizing the metabolism of Dehalococcoides with a constraint-based model |
| Q57016789 | Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism |
| Q51705326 | Comparative metabolic capabilities for Micrococcus luteus NCTC 2665, the "Fleming" strain, and actinobacteria |
| Q48080782 | Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338. |
| Q28754423 | Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks |
| Q28474659 | Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation |
| Q34649443 | Current progress in computational metabolomics |
| Q27679789 | Deamination of 6-Aminodeoxyfutalosine in Menaquinone Biosynthesis by Distantly Related Enzymes |
| Q38357406 | Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon |
| Q89420901 | Development and validation of an updated computational model of Streptomyces coelicolor primary and secondary metabolism |
| Q46809688 | Development of fungal cell factories for the production of secondary metabolites: Linking genomics and metabolism |
| Q42239949 | Diversity of Streptomyces spp. in Eastern Himalayan region - computational RNomics approach to phylogeny. |
| Q34077619 | Elucidation of the functional metal binding profile of a Cd(II)/Pb(II) sensor CmtR(Sc) from Streptomyces coelicolor |
| Q37887690 | Engineering antibiotic production and overcoming bacterial resistance |
| Q38806940 | Engineering microbial hosts for production of bacterial natural products |
| Q50540747 | Enhancement of rapamycin production by metabolic engineering in Streptomyces hygroscopicus based on genome-scale metabolic model |
| Q99562334 | Enzyme-Constrained Models and Omics Analysis of Streptomyces coelicolor Reveal Metabolic Changes that Enhance Heterologous Production |
| Q33398181 | Flux balance analysis of primary metabolism in Chlamydomonas reinhardtii |
| Q42130341 | GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism |
| Q36592439 | Genome Analysis of Structure-Function Relationships in Respiratory Complex I, an Ancient Bioenergetic Enzyme |
| Q48244069 | Genome-based phylogenetic analysis of Streptomyces and its relatives |
| Q51032785 | Genome-scale analysis of Mannheimia succiniciproducens metabolism |
| Q43834980 | Genome-scale analysis of the metabolic networks of oleaginous Zygomycete fungi |
| Q38063161 | Genome-scale metabolic model in guiding metabolic engineering of microbial improvement |
| Q28635799 | Genome-scale metabolic model of Rhodococcus jostii RHA1 (iMT1174) to study the accumulation of storage compounds during nitrogen-limited condition |
| Q51694627 | Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production. |
| Q36922829 | Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement |
| Q37730808 | Genome-scale metabolic network reconstruction of Saccharopolyspora spinosa for spinosad production improvement |
| Q42632521 | Genome-scale metabolic representation of Amycolatopsis balhimycina |
| Q33391538 | Genome-scale models of bacterial metabolism: reconstruction and applications |
| Q33944852 | Genome-scale reconstruction and in silico analysis of the Ralstonia eutropha H16 for polyhydroxyalkanoate synthesis, lithoautotrophic growth, and 2-methyl citric acid production |
| Q46655875 | Genome-scale reconstruction of Salinispora tropica CNB-440 metabolism to study strain-specific adaptation. |
| Q42178119 | Genome‐Based Studies of Marine Microorganisms to Maximize the Diversity of Natural Products Discovery for Medical Treatments |
| Q39979782 | Hierarchical amino acid utilization and its influence on fermentation dynamics: rifamycin B fermentation using Amycolatopsis mediterranei S699, a case study |
| Q35851429 | IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites |
| Q33237950 | Identifying metabolic enzymes with multiple types of association evidence |
| Q36321025 | Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation |
| Q48024061 | Iterative marker excision system |
| Q46363832 | Knowns and unknowns of membrane lipid synthesis in streptomycetes. |
| Q30758202 | MEMOSys 2.0: an update of the bioinformatics database for genome-scale models and genomic data |
| Q34122951 | MetRxn: a knowledgebase of metabolites and reactions spanning metabolic models and databases |
| Q33759920 | Metabolic and evolutionary insights into the closely-related species Streptomyces coelicolor and Streptomyces lividans deduced from high-resolution comparative genomic hybridization. |
| Q83719823 | Metabolic flexibility of D-ribose producer strain of Bacillus pumilus under environmental perturbations |
| Q37063035 | Metabolic flux analysis and metabolic engineering of microorganisms |
| Q34010644 | Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger |
| Q33546187 | Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor |
| Q30506017 | Metabolic modeling of Chlamydomonas reinhardtii: energy requirements for photoautotrophic growth and maintenance |
| Q35742362 | Metabolic modeling of a mutualistic microbial community. |
| Q42281167 | Metabolic network model guided engineering ethylmalonyl-CoA pathway to improve ascomycin production in Streptomyces hygroscopicus var. ascomyceticus |
| Q33235593 | Metabolite coupling in genome-scale metabolic networks |
| Q39891344 | Metabolomic characterization of the salt stress response in Streptomyces coelicolor |
| Q59641095 | Metabolomics analysis I. Selection of biological samples and practical aspects preceding sample preparation |
| Q30401265 | Metabolomics investigation of recombinant mTNFα production in Streptomyces lividans |
| Q24756922 | Microbial metabolism of quorum-sensing molecules acyl-homoserine lactones, γ-heptalactone and other lactones |
| Q35193476 | Modeling methanogenesis with a genome-scale metabolic reconstruction of Methanosarcina barkeri |
| Q55398577 | Modelling the metabolism of protein secretion through the Tat route in Streptomyces lividans. |
| Q50249177 | NAD(+)-specific glutamate dehydrogenase (EC.1.4.1.2) in Streptomyces coelicolor; in vivo characterization and the implication for nutrient-dependent secondary metabolism |
| Q39206378 | OsdR of Streptomyces coelicolor and the Dormancy Regulator DevR of Mycobacterium tuberculosis Control Overlapping Regulons |
| Q30317077 | Oxygen-dependent control of respiratory nitrate reduction in mycelium of Streptomyces coelicolor A3(2). |
| Q34068514 | Parallelization of Nullspace Algorithm for the computation of metabolic pathways |
| Q28830295 | Phylogenomic Analysis of Natural Products Biosynthetic Gene Clusters Allows Discovery of Arseno-Organic Metabolites in Model Streptomycetes |
| Q38968451 | Promise and reality in the expanding field of network interaction analysis: metabolic networks |
| Q58601350 | RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor |
| Q33285703 | RMBNToolbox: random models for biochemical networks |
| Q33559638 | Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach |
| Q35778056 | Reconstruction and in silico analysis of an Actinoplanes sp. SE50/110 genome-scale metabolic model for acarbose production |
| Q45002296 | Reconstruction of a high-quality metabolic model enables the identification of gene overexpression targets for enhanced antibiotic production in Streptomyces coelicolor A3(2). |
| Q29616018 | Reconstruction of biochemical networks in microorganisms |
| Q39577241 | Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production |
| Q58727801 | Regulation of ATP levels in Escherichia coli using CRISPR interference for enhanced pinocembrin production |
| Q46494798 | Selection of objective function in genome scale flux balance analysis for process feed development in antibiotic production |
| Q39393882 | Simple topological properties predict functional misannotations in a metabolic network |
| Q33248812 | Stem-loop structures in prokaryotic genomes |
| Q88934294 | Streptomyces species: Ideal chassis for natural product discovery and overproduction |
| Q27688888 | Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway |
| Q38183353 | Synthetic biology of avermectin for production improvement and structure diversification. |
| Q26772223 | Systems Biology Approaches to Understand Natural Products Biosynthesis |
| Q35228785 | The -omics Era- Toward a Systems-Level Understanding of Streptomyces |
| Q59806072 | The metabolic switch can be activated in a recombinant strain of Streptomyces lividans by a low oxygen transfer rate in shake flasks |
| Q41199271 | The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways |
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