Padraic G. Fallon

researcher

Born 2000-01-01

Padraic G. Fallon is …
instance of (P31):
humanQ5

External links are
P2798Loop ID64475
P496ORCID iD0000-0002-8401-7293
P1153Scopus author ID7102455344

P69educated atTrinity College DublinQ258464
P108employerUniversity of CambridgeQ35794
Trinity College DublinQ258464
Bangor University School of Biological SciencesQ86019412
Bangor University School of ChemistryQ86020388
University of Dublin Trinity College School of MedicineQ101071158
P734family nameFallonQ13560477
FallonQ13560477
FallonQ13560477
P735given namePadraicQ27826963
PadraicQ27826963
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q33858072A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming.
Q50492821A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner.
Q49547979A novel role for the macrophage galactose-type lectin (MGL) receptor in mediating von Willebrand factor clearance.
Q33427139A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria
Q37397800A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis.
Q33954369A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins
Q57792387ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism
Q54604252AGA/AGG codon usage in parasites: implications for gene expression in Escherichia coli.
Q33558189Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells
Q39558657Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide.
Q44321607Active immunization of mice with Schistosoma mansoni worm membrane antigens enhances efficacy of praziquantel
Q92255149Addition of a Viral Immunomodulatory Domain to Etanercept Generates a Bifunctional Chemokine and TNF Inhibitor
Q43145317Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis
Q38334612Alterations in cytochrome-c oxidase expression between praziquantel-resistant and susceptible strains of Schistosoma mansoni.
Q35148413An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes.
Q52605903An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia.
Q35671246Bcl11b is essential for group 2 innate lymphoid cell development
Q54378086Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells.
Q41882583Btk regulates macrophage polarization in response to lipopolysaccharide.
Q82773605C-type lectin SIGN-R1 has a role in experimental colitis and responsiveness to lipopolysaccharide
Q34153275Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.
Q40260026Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis.
Q47441510Composition of the Schistosoma mansoni worm secretome: Identification of immune modulatory Cyclophilin A.
Q57614270Construction of an sIgE:FLAG-mIgE:GFP Reporter Mouse Strain
Q37358129Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice.
Q36179742Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27
Q42944812Decoy receptors in the regulation of T helper cell type 2 responses
Q58312787Defective in vivo induction of functional type 2 cytokine responses in aged mice
Q46035312Design, synthesis, and pharmacological effects of a cyclization-activated steroid prodrug for colon targeting in inflammatory bowel disease.
Q90140576Determining Coreceptor Expression and Function in Murine ILC2 Through Flow Cytometry Characterization and Coculture Techniques
Q54199827Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific.
Q97559304Dysregulated skin barrier function in Tmem79 mutant mice promotes IL-17A-dependent spontaneous skin and lung inflammation
Q36770778Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus
Q58312867Effect of praziquantel and oxamniquine treatment on human isotype responses to Schistosoma mansoni: elevated IgE to adult worm
Q46834406Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease
Q43526727Efficacy of treatment of murineSchistosoma mansoniinfections with praziquantel and oxamniquine correlates with infection intensity: role of host antibody
Q73441091Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Schistosoma mansoni infection of CD4-depleted mice
Q71120824Enhancement of Schistosoma mansoni infectivity by intradermal injections of larval extracts: a putative role for larval proteases
Q27347667Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses
Q42639995Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion
Q44831441Evaluation of immune dependence of anthelmintic treatment of Heligmosomoides polygyrus in CBA/Ca mice
Q28296042Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo
Q93075093Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice
Q36916564Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase
Q36770768Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
Q24604033Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment
Q35792915Functional conservation of an ancestral Pellino protein in helminth species
Q46707680Generation of parasite antigens for use in Toll-like receptor research
Q36389520Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses
Q47552930Helminth Modulation of Lung Inflammation.
Q53880583Helminth infection protects mice from anaphylaxis via IL-10-producing B cells.
Q38071858Helminth therapies: translating the unknown unknowns to known knowns
Q37669972Helminth-derived immunomodulatory molecules
Q51827445Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness.
Q91770244Highly efficient CRISPR-targeting of the murine Hipp11 intergenic region supports inducible human transgene expression
Q85189806Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea
Q38907502Hypoxia-dependent regulation of inflammatory pathways in immune cells
Q40172237IL-17 Receptor A Maintains and Protects the Skin Barrier To Prevent Allergic Skin Inflammation.
Q28237337IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration
Q37474764IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
Q54376306IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss.
Q40058815IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation.
Q51708862IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13.
Q40118341ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
Q45254074Identification of a functioning mitochondrial uncoupling protein 1 in thymus
Q24676901Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
Q34695691Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis
Q58312874IgG4 and IgE responses to Schistosoma mansoni adult worms after treatment
Q50658066Images of mitochondrial UCP 1 in mouse thymocytes using confocal microscopy.
Q35224451Immune-dependent chemotherapy of schistosomiasis
Q44155273Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice
Q42462315Impaired development of Th2 cells in IL-13-deficient mice.
Q79984979Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism
Q36371279Inhibition of type 1 cytokine-mediated inflammation by a soluble CD30 homologue encoded by ectromelia (mousepox) virus
Q47242113Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
Q47177714Innate lymphoid cells and parasites: ancient foes with shared history
Q38022971Innate type 2 cells and asthma
Q38783993Interleukin 33: an innate alarm for adaptive responses beyond Th2 immunity-emerging roles in obesity, intestinal inflammation, and cancer
Q93133573Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction
Q38941989Intestinal expression of Fas and Fas ligand is upregulated by bacterial signaling through TLR4 and TLR5, with activation of Fas modulating intestinal TLR-mediated inflammation
Q44427614Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent
Q52723589Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Q58312778Juvenile Rhesus Monkeys Have Lower Type 2 Cytokine Responses than Adults after Primary Infection withSchistosoma mansoni
Q58312713Juvenile rhesus monkeys have more colonic granulomas than adults after primary infection with Schistosoma mansoni
Q89837711Keratinocyte interleukin-36 receptor expression orchestrates psoriasiform inflammation in mice
Q45182349Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome
Q36137526Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling
Q41436003Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.
Q52620496Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier.
Q42989196Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function
Q47310131Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL-9 and are differentially dependent on Th2 cytokines
Q34106637MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion
Q26774652Macrophage and Innate Lymphoid Cell Interplay in the Genesis of Fibrosis
Q63257866Mast Cells as Sensors of Cell Injury through IL-33 Recognition
Q44171334Mitochondrial uncoupling protein 1 expression in thymocytes.
Q59419057MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice
Q39299024N-linked glycan truncation causes enhanced clearance of plasma-derived von Willebrand factor.
Q38750537N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance.
Q37345931Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice
Q87862057Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis
Q53178921New Insights into IL-10 Dependent and IL-10 Independent Mechanisms of Regulatory B Cell Immune Suppression.
Q24630261Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
Q39263391Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia
Q41529474PD-L1hi B cells are critical regulators of humoral immunity.
Q43058020Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection
Q36804679Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis
Q53726422Pathogen-derived immunomodulatory molecules. Preface.
Q36571448Pathogen-derived immunomodulatory molecules: future immunotherapeutics?
Q28513622Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
Q49131456Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung.
Q56835746Periodate-sensitive immunological cross-reactivity between keyhole limpet haemocyanin (KLH) and serodiagnostic Schistosoma mansoni egg antigens
Q37871567Previous infection with the nematode Nippostrongylus brasiliensis alters the immune specific response against Chlamydophila abortus infection.
Q52587242Primitive Toll signalling: bugs, flies, worms and man.
Q46546477Promutagenic methylation damage in liver DNA of mice infected with Schistosoma mansoni.
Q60034598Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation
Q73510520Protection of mice against Schistosoma mansoni infection by passive transfer of sera from infected rabbits
Q56835769Quantification of praziquantel-induced damage on the surface of adultSchistosoma mansoni worms: estimation of esterase and alkaline phosphatase activity
Q39314627Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies
Q36713986Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2
Q37319845Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Q83374824Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model
Q125474122Retinoic Acid–Related Orphan Receptor α Is Required for Generation of Th2 Cells in Type 2 Pulmonary Inflammation
Q56901349Role for CTLA-4 but not CD25+ T cells during Schistosoma mansoni infection of mice
Q36399613SIGN-R1 contributes to protection against lethal pneumococcal infection in mice.
Q50100977SIPPET: insights into factor VIII immunogenicity.
Q35102288SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses.
Q112299672SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
Q59127674Schistosoma "Eggs-Iting" the Host: Granuloma Formation and Egg Excretion
Q92354831Schistosoma mansoni Worm Infection Regulates the Intestinal Microbiota and Susceptibility to Colitis
Q36403130Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity
Q47231413Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages
Q50956112Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates.
Q80098643Schistosome resistance to praziquantel
Q48568906Schistosome resistance to praziquantel: Fact or artifact?
Q37552637Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year
Q34451078Soluble IL-2Rα (sCD25) exacerbates autoimmunity and enhances the development of Th17 responses in mice
Q42206731Specific intracellular adhesion molecule-grabbing nonintegrin R1 is not involved in the murine antibody response to pneumococcal polysaccharides.
Q92776774Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β
Q36526371Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity
Q36743554Suppression of TH2-type allergic reactions by helminth infection.
Q43694518Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.
Q73510545Synergistic action of cyclosporin A and polyspecific rabbit anti-sera against murine Schistosoma mansoni
Q35193671T helper type-2 cytokine responses: potential therapeutic targets.
Q80094797T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation
Q41019222Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.
Q44129501Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells.
Q41915030The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection
Q36876563The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages
Q54241841The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis.
Q35116283The alarmin IL-33 promotes regulatory T-cell function in the intestine
Q83420383The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses
Q88631930The emergence of the IL-36 cytokine family as novel targets for inflammatory diseases
Q46867606The generation of regulatory B cells by helminth parasites
Q37151880The helminth T2 RNase ω1 promotes metabolic homeostasis in an IL-33- and group 2 innate lymphoid cell-dependent mechanism.
Q91776465The high and lows of type 2 asthma and mouse models
Q35167567The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells
Q46827571The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.
Q36764281The schistosoma granuloma: friend or foe?
Q36127141The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α.
Q49933333The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses.
Q39867601Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response.
Q55284399Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.
Q28511427Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects
Q47779885Toll IL-1R8/single Ig IL-1-related receptor regulates psoriasiform inflammation through direct inhibition of innate IL-17A expression by γδ T cells
Q52413082Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis.
Q24629126Transcription factor RORα is critical for nuocyte development
Q37089055Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells
Q34395286Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice
Q86423484Ursodeoxycholic acid attenuates colonic epithelial secretory function
Q35358840Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer
Q81752963Why does work on same mouse models give different results?
Q60034580von Willebrand factor arginine 1205 substitution results in accelerated macrophage-dependent clearancein vivo