The GTP-binding protein, Go, regulates neuronal calcium channels

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The GTP-binding protein, Go, regulates neuronal calcium channels is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1011223102
P356DOI10.1038/325445A0
P8608Fatcat IDrelease_fqygyvnzpvah5b7cc55hpzbblm
P698PubMed publication ID2433590

P2093author name stringSchultz G
Hescheler J
Trautwein W
Rosenthal W
P2860cites workImproved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Opiate-dependent modulation of adenylate cyclaseQ28323626
Inositol trisphosphate, a novel second messenger in cellular signal transductionQ29618048
G proteins and dual control of adenylate cyclaseQ34255388
Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesiumQ37341930
Calcium channel modulation by neurotransmitters, enzymes and drugsQ40089436
Modulation of Ca current during the phosphorylation cycle in the guinea pig heartQ42487262
GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channelsQ42507048
Culture and characteristics of hormone-responsive neuroblastoma X glioma hybrid cellsQ42818907
Regulation of calcium currents by a GTP analogue: potentiation of (-)-baclofen-mediated inhibitionQ44353680
Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels by a guanine nucleotide analogueQ44618242
On the mechanism of muscarinic inhibition of the cardiac Ca currentQ46469304
GTP-binding proteins. One molecular machine can transduce diverse signalsQ47207749
Identification and characterization of the 35-kDa beta subunit of guanine-nucleotide-binding proteins by an antiserum raised against transducin.Q50908535
GTP-binding proteins couple cardiac muscarinic receptors to a K channel.Q53737873
Effects of dopamine and noradrenaline on Ca channels of cultured sensory and sympathetic neurons of chick.Q54148383
The GTP-binding regulatory proteins of neuroblastoma x glioma, NG108-15, and glioma, C6, cells. Immunochemical evidence of a pertussis toxin substrate that is neither Ni nor No.Q55487843
Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranesQ59066015
GTP-dependent inhibition of cardiac adenylate cyclase by muscarinic cholinergic agonistsQ59345541
gamma-Aminobutyric acid-induced depression of calcium currents of chick sensory neuronsQ68935430
Neurotransmitters decrease the calcium conductance activated by depolarization of embryonic chick sensory neuronesQ72510114
P433issue6103
P407language of work or nameEnglishQ1860
P304page(s)445-447
P577publication date1987-01-01
P1433published inNatureQ180445
P1476titleThe GTP-binding protein, Go, regulates neuronal calcium channels
P478volume325

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cites work (P2860)
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Q52215310Cellular distribution of G protein Go alpha in pituitary lactotrophs: effects of dopamine.
Q38347498Changes of the level of G protein alpha-subunit mRNA by tolerance to and withdrawal from butorphanol
Q42793370Characterization of GTP-binding proteins in Golgi-associated membrane vesicles from rat adipocytes
Q41618835Characterization of beta-125I-endorphin cross-linked proteins in NG108-15 cell membranes. A 25-kilodalton protein with properties of delta-opioid-binding site
Q35012823Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus→midbrain pathway for feeding behavior
Q42479658Cholera toxin differentially decreases membrane levels of alpha and beta subunits of G proteins in NG108-15 cells
Q73170897Cholera toxin effects on body temperature changes induced by morphine
Q47754598Chronic ethanol promotes the neuronal differentiation of NG108-15 cells independently of toxin-sensitive G-proteins
Q55482727Chronic ethanol reduces immunologically detectable Gq alpha/11 alpha in NG108-15 cells.
Q55485035Chronic exposure of NG 108-15 cells to opiate agonists does not alter the amount of the guanine nucleotide-binding proteins Gi and Go.
Q42489038Chronic exposure to pertussis toxin alters muscarinic receptor-mediated regulation of cyclic AMP metabolism in neuroblastoma x glioma NG108-15 hybrid cells
Q51771820Chronic membrane depolarization regulates the level of the guanine nucleotide binding protein Go alpha in cultured neuronal cells.
Q48656536Chronic stimulation of D2 dopamine receptors specifically inhibits calcium but not potassium currents in rat lactotrophs
Q34246224Complex regulation of calcium current in cardiac cells. Dependence on a pertussis toxin-sensitive substrate, adenosine triphosphate, and an alpha 1-adrenoceptor.
Q48645801Conversion of 3H-Nitrendipine Binding to the Low Affinity Binding State Following the Treatment of Hippocampal Slices with Morphine
Q36893151Coupling specificity of NOP opioid receptors to pertussis-toxin-sensitive Galpha proteins in adult rat stellate ganglion neurons using small interference RNA
Q36064027Cyclic AMP-independent, dual regulation of voltage-dependent Ca2+ currents by LHRH and somatostatin in a pituitary cell line
Q48108808Decreased G-protein-mediated regulation and shift in calcium channel types with age in hippocampal cultures.
Q44338873Delta opioid receptor mediates phospholipase C activation via Gi in Xenopus oocytes
Q44349452Delta-opioid receptors on astroglial cells in primary culture: mobilization of intracellular free calcium via a pertussis sensitive G protein.
Q38341212Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2
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Q44346961Different mechanisms mediate development and expression of tolerance and dependence for peripheral mu-opioid antinociception in rat.
Q48524605Differential G protein-mediated coupling of D2 dopamine receptors to K+ and Ca2+ currents in rat anterior pituitary cells
Q38322143Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.
Q41951760Differential effects of suramin on the coupling of receptors to individual species of pertussis-toxin-sensitive guanine-nucleotide-binding proteins
Q48183169Differential expression of alpha-subunits of G-proteins in human neuroblastoma-derived cell clones
Q38335869Differential interactions of the C terminus and the cytoplasmic I-II loop of neuronal Ca2+ channels with G-protein alpha and beta gamma subunits. I. Molecular determination
Q38335866Differential interactions of the C terminus and the cytoplasmic I-II loop of neuronal Ca2+ channels with G-protein alpha and beta gamma subunits. II. Evidence for direct binding
Q42120332Differential regulation of amounts of the guanine-nucleotide-binding proteins Gi and Go in neuroblastoma x glioma hybrid cells in response to dibutyryl cyclic AMP
Q49043065Differential sensitivity to blockade by 4-aminopyridine of presynaptic receptors regulating [3H]acetylcholine release from rat hippocampus
Q34285121Differentiation of human T cells alters their repertoire of G protein alpha-subunits.
Q38204206Direct G-protein regulation of Ca2+ channels
Q69046527Direct coupling of a G-protein to dihydropyridine binding sites
Q36213932Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells
Q69364357Direct modulation of voltage-dependent calcium channels by muscarinic activation of a pertussis toxin-sensitive G-protein in hippocampal neurons
Q41979725Distribution of G-proteins in rat liver plasma-membrane domains and endocytic pathways
Q29618841Diversity of G proteins in signal transduction
Q28321131Do intracellular Ca2+ activity and hepatic glutathione play a role in the pathogenesis of lithocholic acid-induced cholestasis?
Q67912188Dopamine D2Receptors Attenuate Phosphatidylisitol 4,5-Bisphosphate in Synaptosomal Membranes from Rat Neostriatum
Q44423158Dopamine receptors on adrenal chromaffin cells modulate calcium uptake and catecholamine release
Q48819915Dopamine regulates the electrical activity of frog melanotrophs through a G protein-mediated mechanism
Q68254506Double-pulse calcium channel current facilitation in adult rat sympathetic neurones
Q42810765Down-Modulation of Ca2+ Channels by Endogenously Released ATP and Opioids: from the Isolated Chromaffin Cell to the Slice of Adrenal Medullae
Q33787370Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents
Q68364548Effect of different Ca2+ entry blockers on dopamine-induced inhibition of in vitro prolactin secretion
Q44015282Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity
Q71835903Effect of morphine on aluminium fluoride and dibutyryl-cyclic AMP induced reduction of field potentials in hippocampal slices
Q69377374Effects of beta-endorphin, met-enkephalin, and dynorphin A on basal and stimulated insulin secretion in the mouse
Q41091379Effects of intravenous anesthetics on neurons of the central nervous system: mechanisms of cellular and molecular action
Q73163953Effects of morphine on the electroencephalograms of neonates: a prospective, observational study
Q44340284Effects of pertussis toxin on opioid regulation of catecholamine release from rat and guinea pig brain slices
Q41959858Elevated levels of the alpha subunit of GTP-binding protein Go in cerebrospinal fluid of patients with neurological disorders
Q43420040Elevated levels of the guanine nucleotide binding protein, Go, are associated with differentiation of neuroblastoma x glioma hybrid cells
Q37803251Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays.
Q44348036Endomorphins inhibit high-threshold Ca2+ channel currents in rodent NG108-15 cells overexpressing mu-opioid receptors.
Q42161335Enkephalin activates the phospholipase C/Ca2+ system through cross-talk between opioid receptors and P2-purinergic or bradykinin receptors in NG 108-15 cells. A permissive role for pertussis toxin-sensitive G-proteins
Q36921707Epinephrine suppresses rap1B.GAP-activated GTPase activity in human platelets
Q34666518Ethanol and opioid receptor signalling
Q48638150Ethanol suppresses neuronal Ca2+ currents by effects on intracellular signal transduction
Q44337880Evidence for delta-opioid binding and GTP-regulatory proteins in 5-day-old rat brain membranes
Q28241740Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells
Q36946616Evidence for the implication of phosphoinositol signal transduction in mu-opioid inhibition of DNA synthesis
Q37999097Evidence from basic research for opioid combinations
Q41977350Evidence that a pertussis-toxin-sensitive substrate is involved in the stimulation by epidermal growth factor and vasopressin of plasma-membrane Ca2+ inflow in hepatocytes
Q48876351Excitotoxin lesion of nucleus basalis causes a specific decrease in Go mRNA in cerebral cortex. Sensitivity to MK-801.
Q36802558Expression and Function of the Calcitonin Gene Products
Q41063798Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype
Q54044445Expression of alpha subunit of guanine nucleotide-binding protein Go in Merkel cell carcinoma.
Q36432557Expression of the Aplysia californica rho gene in Escherichia coli: purification and characterization of its encoded p21 product
Q41333862Factors determining specificity of signal transduction by G-protein-coupled receptors. Regulation of signal transfer from receptor to G-protein.
Q38588139From GTP and G proteins to TRPC channels: a personal account
Q40784976Functional properties of Cav1.3 (alpha1D) L-type Ca2+ channel splice variants expressed by rat brain and neuroendocrine GH3 cells.
Q33576434Functional reconstitution of skeletal muscle Ca2+ channels: separation of regulatory and channel components
Q48453380G Protein Modulation of ω‐Conotoxin Binding Sites in Neuroblastoma X Glioma NG 108‐15 Hybrid Cells
Q28608943G Proteins and Opioid Receptor-Mediated Signalling
Q24323106G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart
Q36410408G protein control of potassium channel activity in a mast cell line
Q38349930G protein interaction with K+ and Ca2+ channels
Q33568483G protein mRNA mapped in rat brain by in situ hybridization
Q36534553G protein modulation of calcium entry and transmitter release
Q37975492G proteins as regulators of ion channel function
Q35893040G proteins couple alpha-adrenergic and GABAb receptors to inhibition of peptide secretion from peripheral sensory neurons
Q71246418G proteins regulate dihydropyridine binding to moss plasma membranes
Q42528309G proteins, adenylyl cyclase and related phosphoproteins in the developing rat heart
Q36762829G(o) transduces GABAB-receptor modulation of N-type calcium channels in cultured dorsal root ganglion neurons
Q39484927G-protein activation mediates prepulse facilitation of Ca2+ channel currents in bovine chromaffin cells
Q40875750G-protein coupling of mu-opioid receptors (OP3): elevated basal signalling activity
Q59095470G-protein modulation of ion permeation through N-type calcium channels
Q48205227G-proteins in Torpedo marmorata electric organ. Differential distribution in pre- and post-synaptic membranes and synaptic vesicles
Q69234221G-proteins in neuronal and sensory tissue from invertebrates
Q42099212G-proteins in skeletal muscle. Evidence for a 40 kDa pertussis-toxin substrate in purified transverse tubules
Q38315479GABAB receptor modulation of Ca2+ currents in rat sensory neurones by the G protein G(0): antisense oligonucleotide studies
Q44867236GABAB receptors couple to G proteins Go, Go* and Gi1 but not to Gi2.
Q55486355GTP analogues cause release of the alpha subunit of the GTP binding protein, GO, from the plasma membrane of NG108-15 cells.
Q37290313GTP-binding proteins inhibit cAMP activation of chloride channels in cystic fibrosis airway epithelial cells
Q48789103Galanin Reduces Carbachol Stimulation of Phosphoinositide Turnover in Rat Ventral Hippocampus by Lowering Ca2+Influx Through Voltage-Sensitive Ca2+Channels
Q34593268Globin gene expression in correlation with G protein-related genes during erythroid differentiation
Q36279301Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain
Q48325144Guanine nucleotide binding proteins mediate D2 dopamine receptor activation of a potassium channel in rat lactotrophs
Q33575763Guanine nucleotide-binding protein Go-induced coupling of neuropeptide Y receptors to Ca2+ channels in sensory neurons
Q34577900Guanine nucleotide-binding protein, alpha i-3, directly activates a cation channel in rat renal inner medullary collecting duct cells
Q33635134Guanine nucleotide-binding proteins that enhance choleragen ADP-ribosyltransferase activity: nucleotide and deduced amino acid sequence of an ADP-ribosylation factor cDNA.
Q42037487Guanosine-5'-O-(3-thiotriphosphate) modifies kinetics of voltage-dependent calcium current in chick sensory neurons
Q41979517Guinea-pig treatment with pertussis toxin suppresses macrophage-dependent bronchoconstriction by fMLP and fails to inhibit the effects of PAF
Q67879377Heterogeneity of Guanine Nucleotide Binding Proteins in Human Red Blood Cell Membranes
Q44333842Heterologous desensitization of opioid-stimulated Ca2+ increase by bradykinin or ATP in NG108-15 cells
Q38304353Heterotrimeric G proteins involved in the modulation of voltage-dependent calcium channels of neuroendocrine cells
Q44043711High extracellular Ca2+ and Mg2+ stimulate accumulation of inositol phosphates in bovine parathyroid cells
Q40642162Homologous and unique G protein alpha subunits in the nematode Caenorhabditis elegans
Q42856712Identification and purification from bovine brain of a guanine-nucleotide-binding protein distinct from Gs, Gi and Go.
Q69179667Identification of both Gi2 and a novel, immunologically distinct, form of Go in rat myometrial membranes
Q48847914Identification of two distinct isoforms of the guanine nucleotide binding protein G0 in neuroblastoma X glioma hybrid cells: independent regulation during cyclic AMP-induced differentiation
Q36755459Immunoblots with rhodopsin antisera suggest that a purified mu opioid binding protein has structural characteristics of a G-protein-coupled receptor
Q44330557Immunoprecipitation of high-affinity, guanine nucleotide-sensitive, solubilized mu-opioid receptors from rat brain: coimmunoprecipitation of the G proteins G(alpha o), G(alpha i1), and G(alpha i3).
Q44760716In vivo morphine decreases [3H]nimodipine receptor binding in rat brain regions
Q40896311Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast
Q44983528Inhibition by anandamide and synthetic cannabimimetics of the release of [3H]D-aspartate and [3H]GABA from synaptosomes isolated from the rat hippocampus
Q46658104Inhibition of Ca2+ and K+ channels in sympathetic neurons by neuropeptides and other ganglionic transmitters
Q41683094Inhibition of Ca2+ channels via alpha 2-adrenergic and muscarinic receptors in pheochromocytoma (PC-12) cells
Q68172366Inhibition of calcium currents by noradrenaline, somatostatin and opioids in guinea-pig submucosal neurones
Q40488907Inhibition of insulin secretion: A fail-safe system
Q42148601Inhibition of mink lung epithelial cell proliferation by transforming growth factor-beta is coupled through a pertussis-toxin-sensitive substrate
Q70178930Inhibitory effects of pertussis toxin on a depolarization-evoked Ca2+ influx in NG108-15 cells
Q43662215Inhibitory modulation of fast and slow Ca2+-currents in neuroblastoma × glioma cells during differentiation
Q39618623Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease
Q36592492Intracellular regulation of ion channels in cell membranes
Q67276978Intracerebroventricular treatment of mice with pertussis toxin induces hyperalgesia and enhances 3H-nitrendipine binding to synaptic membranes: similarity with morphine tolerance
Q44333897Intrathecal Pertussis Toxin but not Cyclic AMP Blocks Kappa Opioid-Induced Antinociception in rat
Q36539104Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus
Q67601069Involvement of a pertussis toxin-sensitive G-protein in excitation-contraction coupling of intact and cut-end voltage-clamped skeletal muscle fibres
Q67982005Ischemia of rat brain decreases pertussis toxin-catalyzed [32P]ADP ribosylation of GTP-binding proteins (Gi1 and G0) in membranes
Q36761587Isolation and expression of a novel chick G-protein cDNA coding for a G alpha i3 protein with a G alpha 0 N-terminus
Q48205245Localization of mRNAs encoding the alpha-subunits of signal-transducing G-proteins within rat brain and among peripheral tissues
Q37111241Long-chain fatty acids activate calcium channels in ventricular myocytes
Q44346002Long-term regulation of opioid receptors in neuroblastoma and lymphoma cell lines
Q42483588MMQ cells: a model for evaluating the role of g proteins in the modulation of prolactin release
Q69024934Magnetic fields inhibit opioid-mediated 'analgesic' behaviours of the terrestrial snail, Cepaea nemoralis
Q41187426Mechanism of inhibition of calcium channels in rat nucleus tractus solitarius by neurotransmitters
Q44042886Mechanisms of NE-induced reduction of Ca current in single smooth muscle cells from guinea pig vas deferens
Q72091222Mechanisms of antagonistic action of internal Ca2+ on serotonin-induced potentiation of Ca2+ currents in Helix neurones
Q34458100Mechanisms of modulation of voltage-dependent calcium channels by G proteins
Q36468622Mechanisms of opioid actions on neurons of the locus coeruleus
Q40485151Membrane-delimited cell signaling complexes: Direct ion channel regulation by G Proteins
Q44352464Methadone-induced desensitization of the delta-opioid receptor is mediated by uncoupling of receptor from G protein
Q39455257Mobilization of Ca2+ from intracellular stores in transfected neuro2a cells by activation of multiple opioid receptor subtypes.
Q45914141Modulation of Ca-channel current by an adenosine analog mediated by a GTP-binding protein in chick sensory neurons.
Q41214714Modulation of Ca2+ channels by G-protein beta gamma subunits
Q38355262Modulation of G protein alpha-subunit mRNA levels in discrete rat brain regions by cerebroventricular infusion of ginsenoside Rc and Rg1
Q49050274Modulation of gamma-aminobutyric acid release in cerebral cortex by fluoride, phorbol ester, and phosphodiesterase inhibitors: differential sensitivity of acetylcholine release to fluoride and K+ channel blockers
Q44345324Modulation of high-voltage activated Ca2+ channels in the rat periaqueductal gray neurons by mu-type opioid agonist
Q40950178Molecular biology of calcium channels
Q36850452Molecular cloning of heterotrimeric G-protein alpha-subunits in chicken pineal gland.
Q33721127Molecular mechanisms of go signaling
Q40921500Molecular pharmacology of alpha 2-adrenoceptor subtypes
Q72070699Morphine Activates ω‐Conotoxin‐Sensitive Ca2+ Channels to Release Adenosine from Spinal Cord Synaptosomes
Q51381261Morphine decreases the voltage sensitivity of slow sodium channels.
Q41322968Multiple effects of opiates on intracellular calcium level and on calcium uptake in three neuronal cell lines
Q28585725Multiple neurological abnormalities in mice deficient in the G protein Go
Q67915782Muscarinic enhancement of the voltage-dependent calcium current in an identified snail neuron
Q68480391Muscarinic modulation of calcium current in neurones from the interatrial septum of bull-frog heart
Q37550895Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists
Q69028757Myelin basic protein binds GTP at a single site in the N-terminus
Q24633910Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins
Q24647839Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+
Q49046120Neuroblastoma differentiation involves the expression of two isoforms of the alpha-subunit of Go.
Q35241401Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit
Q41276531Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence
Q55483620Neurotransmitters inhibit the omega-conotoxin-sensitive component of Ca current in neuroblastoma � glioma hybrid (NG108-15) cells, not the nifedipine-sensitive component
Q34474040New agents for sedation in the intensive care unit
Q37084176Nitric oxide stimulates the ADP-ribosylation of a 41-kDa cytosolic protein in Dictyostelium discoideum
Q73827227Nociceptin inhibits T-type Ca2+ channel current in rat sensory neurons by a G-protein-independent mechanism
Q55485459Noradrenaline- and Enkephalin-Induced Inhibition of Voltage-Sensitive Calcium Currents in NG108-15 Hybrid Cells.
Q55485460Noradrenaline-Induced Inhibition of Voltage-Sensitive Calcium Currents in NG108-15 Hybrid Cells.
Q43407609Norepinephrine inhibits a Ca2+ current in rat sympathetic neurons via a G-protein
Q42799782Nuclear GTP-binding proteins of Swiss 3T3 cells
Q24309094ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization
Q37205783Occurrence of the alpha subunits of G proteins in cerebral cortex synaptic membrane and postsynaptic density fractions: modulation of ADP-ribosylation by Ca2+/calmodulin
Q43736430Ontogenesis of alpha 2-adrenoceptor coupling with GTP-binding proteins in the rat telencephalon
Q52249402Ontogeny of the GTP-binding protein Go in rat brain and heart.
Q33855336Opiate modulating properties of nociceptin/orphanin FQ.
Q43070545Opiate tolerance and dependence: receptors, G-proteins, and antiopiates
Q44331367Opioid and cannabinoid receptors share a common pool of GTP-binding proteins in cotransfected cells, but not in cells which endogenously coexpress the receptors
Q44347095Opioid receptor and calcium channel regulation of adenylyl cyclase, modulated by GM1, in NG108-15 cells: competitive interactions
Q38085387Opioid receptor interacting proteins and the control of opioid signaling.
Q33687022Opioid receptor signalling mechanisms.
Q37179761Opioid receptor-coupled second messenger systems
Q44339867Opioid receptors in magnesium-digitonin-solubilized rat brain membranes are tightly coupled to a pertussis toxin-sensitive guanine nucleotide-binding protein
Q48643365Opioids potentiate transmitter release from SK-N-SH human neuroblastoma cells by modulating N-type calcium channels
Q69017145Opposing effects of noradrenaline on the two classes of voltage-dependent calcium channels of single vascular smooth muscle cells in short-term primary culture
Q46831533Participation of the protein Go in multiple aspects of behavior in C. elegans
Q69909681Pertussis toxin does not attenuate alpha 2-adrenoceptor mediated inhibition of noradrenaline release in mouse atria
Q33575836Pertussis toxin-insensitive G protein mediates substance P-induced inhibition of potassium channels in brain neurons
Q42466998Pertussis toxin-sensitive G-protein mediates galanin's inhibition of scopolamine-evoked acetylcholine release in vivo and carbachol-stimulated phosphoinositide turnover in rat ventral hippocampus
Q69408841Phorbol ester effects on coupling mechanisms during cholinergic contraction of swine tracheal smooth muscle
Q44351550Phosphorylation promotes the desensitization of the opioid-induced Ca2+ increase in NG108-15 cells
Q69037722Photoactivation of intracellular guanosine triphosphate analogues reduces the amplitude and slows the kinetics of voltage-activated calcium channel currents in sensory neurones
Q68313943Possible Role of GAP-43 in Calcium Regulation/Neurotransmitter Release
Q35672802Post-transcriptional regulation of opioid receptors in the nervous system
Q41017115Potential roles of heterotrimeric G proteins of the endomembrane system
Q42478991Potentiation of transmitter release from NMB human neuroblastoma cells by kappa-opioids is mediated by N-type voltage-dependent calcium channels
Q38693739Presence of Androgen Receptor Variant in Neuronal Lipid Rafts
Q43937868Presynaptic inhibitory action of enkephalin on excitatory transmission in superficial dorsal horn of rat spinal cord
Q44340375Presynaptic kappa-opioid receptors on noradrenergic nerve terminals couple to G proteins and interact with the alpha 2-adrenoceptors
Q48170473Primary structure of bovine cerebellum GTP-binding protein G39 and its effect on the adenylate cyclase system
Q37560417Properties of calcium channels in cardiac muscle and vascular smooth muscle
Q36647631Properties of sympathetic neuromuscular transmission and smooth muscle cell membranes in vascular beds
Q42803502Properties of the voltage-dependent calcium channel of mouse Swiss 3T3 fibroblasts
Q43184524Prostaglandins inhibit secretion of histamine and pancreastatin from isolated rat stomach ECL cells
Q69836120Protein kinase C activation increases noradrenaline release from the rat hippocampus and modifies the inhibitory effect of alpha 2-adrenoceptor and adenosine A1-receptor agonists
Q41822394Purification and characterization of predominant G-protein from bovine lung membranes. Biochemical and immunochemical comparison with Gi1 and Go purified from brain
Q44920668Purification and characterization of subforms of the guanine-nucleotide-binding proteins G alpha i and G alpha o.
Q36618289RNA interference in pain research
Q44348509Receptor-mediated activation of G-proteins by kappa opioid agonists in frog (Rana esculenta) brain membranes
Q41099358Receptors couple to L-type calcium channels via distinct Go proteins in rat neuroendocrine cell lines
Q44343364Reconstitution of partially purified opioid receptors with a GTP-binding protein
Q33649680Reconstitution of rat brain mu opioid receptors with purified guanine nucleotide-binding regulatory proteins, Gi and Go.
Q41775401Refolding of G protein alpha subunits from inclusion bodies expressed in Escherichia coli.
Q42449195Regulation of Basal and stimulated prolactin release in prolactin-secreting rat pituitary tumors*.
Q40642905Regulation of Ca2+ influx during mitosis: Ca2+ influx and depletion of intracellular Ca2+ stores are coupled in interphase but not mitosis
Q37160379Regulation of calcium channel activity by GTP binding proteins and second messengers
Q42443404Regulation of stimulatory adenylyl cyclase signaling during forskolin-induced differentiation of mouse neuroblastoma x rat glioma (NG108-15) cells.
Q37895590Regulatory proteins in presynaptic function
Q33586812Requirement of GTP on somatostatin-induced K+ current in human pituitary tumor cells
Q48695823Robustness of G proteins in Alzheimer's disease: an immunoblot study
Q44077090Role of L-type Ca(2+) channels in pertussis toxin induced antagonism of U50,488H analgesia and hypothermia
Q48828542Role of calcium channels in effects of antidepressant drugs on responsiveness to pain
Q38183790Role of phosphoinositides in the regulation of liver function
Q36659435Role of signal transduction in anesthetic action. Alpha 2 adrenergic agonists
Q42694609Role of the GTP-binding protein G(o) in the suppressant effect of ethanol on voltage-activated calcium channels of murine sensory neurons
Q34167215Roles of G protein subunits in transmembrane signalling.
Q37896261Roles of G proteins in coupling of receptors to ionic channels and other effector systems
Q28202553Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
Q48165516Second messengers associated with the action of AII and dopamine D2 receptors in anterior pituitary. Relationship with prolactin secretion
Q42494619Secretion-stimulating and secretion-inhibiting hormones stimulate high-affinity pertussis-toxin-sensitive GTPases in membranes of a pituitary cell line
Q48167838Selective coupling of mouse brain metabotropic sigma receptor with recombinant Gi1.
Q41071297Selective interactions of mu-opioid receptors with pertussis toxin-sensitive G proteins: involvement of the third intracellular loop and the c-terminal tail in coupling
Q24338196Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit
Q42151281Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins
Q38300728Somatostatin Modulates Voltage‐Dependent Ca 2+ Channels in Gh 3 Cells Via a Specific G o Splice Variant
Q69115007Somatostatin blocks a calcium current in rat sympathetic ganglion neurones
Q69100109Somatostatin induces an inward rectification in rat locus coeruleus neurones through a pertussis toxin-sensitive mechanism
Q41138053Somatostatin inhibits insulin secretion by a G-protein-mediated decrease in Ca2+ entry through voltage-dependent Ca2+ channels in the beta cell
Q41278658Specificity of interaction between receptor and G protein: use of antisense techniques to relate G-protein subunits to function
Q44351408Stimulation of phospholipase C by the cloned mu, delta and kappa opioid receptors via chimeric G alpha(q) mutants
Q41153514Stimulatory effects of opioids on transmitter release and possible cellular mechanisms: overview and original results
Q48321201Structural and functional studies on the G(o) protein
Q36399354Structural heterogeneity of membrane receptors and GTP-binding proteins and its functional consequences for signal transduction
Q30365050Structure and function of G proteins
Q44335232Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a μ opioid
Q41252205Synaptosomal calcium influx is activated by sodium fluoride
Q43938191Synergism in cytosolic Ca2+ mobilization between bradykinin and agonists for pertussis toxin-sensitive G-protein-coupled receptors in NG 108-15 cells
Q47417155Synergistic analgesic effect of propofol-alfentanil combination through detecting the inhibition of cAMP signal pathway
Q42503060Synergistic interaction of muscarinic and opioid receptors with GS-linked neurotransmitter receptors to stimulate adenylyl cyclase activity of rat olfactory bulb
Q42174123Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain
Q39293017Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins
Q36797546The G protein alpha o subunit alters morphology, growth kinetics, and phospholipid metabolism of somatic cells.
Q36572204The G protein-channel connection
Q35228899The Role of GTP-Binding Proteins in Signal Transduction: From the Sublimely Simple to the Conceptually Complex
Q28241365The alpha 2B adrenergic receptor of undifferentiated neuroblastoma x glioma hybrid NG108-15 cells, interacts directly with the guanine nucleotide binding protein, Gi2
Q37563624The calcitonin gene peptides: biology and clinical relevance
Q39631622The chemotactic peptide receptor. A model for future understanding of chemotactic disorders.
Q40800246The effect of dexmedetomidine on the firing properties of STN neurons in Parkinson's disease.
Q55478042The mitogen-activated protein kinase p38-2 is necessary for the inhibition of N-type calcium current by bradykinin.
Q41108830The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin.
Q44350115The negative influence of endogenous opioid receptor activity on the differentiation of the rat pheochromocytoma PC12 cells induced by nerve growth factor
Q68082319The negative inotropic effect of acetylcholine on ferret ventricular myocardium
Q40570003The pharmacology and function of central GABAB receptors.
Q67912962The protective effect of atrial natriuretic peptide (ANP) on cells damaged by oxygen radicals is mediated through elevated CGMP-levels, reduction of calcium-inflow and probably G-proteins
Q73145412The role of G protein activation in the toxicity of amyloidogenic Abeta-(1-40), Abeta-(25-35), and bovine calcitonin
Q37901376The role of G proteins in transmembrane signalling.
Q41138707The stimulatory effect of opioids on cyclic AMP production in SK-N-SH cells is mediated by calcium ions
Q39466253The structure and mechanism of neurotransmitter receptors. Implications for the structure and function of the central nervous system
Q34409714The use of the patch clamp technique to study second messenger-mediated cellular events
Q37603333Tonic inhibition and rebound facilitation of a neuronal calcium channel by a GTP-binding protein
Q41582134Toxins affecting calcium channels in neurons
Q42836747Transforming growth factor beta 1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s).
Q35758968Tumor cell adhesion to the extracellular matrix and signal transduction mechanisms implicated in tumor cell motility, invasion and metastasis
Q42527202Turnover of mu-opioid receptors in neuroblastoma cells
Q42584181Two distinct modulatory effects on calcium channels in adult rat sensory neurons
Q42818974Two forms of G(o) type G proteins: identification and distribution in various rat tissues and cloned cells
Q39375364Urinary trypsin inhibitor prevents uterine muscle contraction by inhibition of Ca++ influx
Q39503567Voltage- and time-dependent inhibition of neuronal calcium channels by a GTP-binding protein in a mammalian cell line
Q33602329Voltage-dependent modulation of N-type calcium channels: role of G protein subunits
Q53042021[Functional guanine nucleotide-binding proteins in receptor-mediated modulation of voltage-dependent ion channels].
Q28142296alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role
Q28582656delta opioid receptor modulation of several voltage-dependent Ca(2+) currents in rat sensory neurons
Q44331267kappa-opioid agonist stimulated regional distribution of [(35)S]GTPgammas binding in butorphanol continuously infused rat.
Q44347905mu-Opioid peptides inhibit thalamic neurons.
Q44344975mu-opioid receptor regulates CFTR coexpressed in Xenopus oocytes in a cAMP independent manner
Q59005805α-Adrenergic inhibition of sympathetic neurotransmitter release mediated by modulation of N-type calcium-channel gating
Q35171345μ-Opioid receptor coupling to Gα(o) plays an important role in opioid antinociception
Q68314713μ-Opioid-receptor-mediated inhibidon of the N-type calcium-channel current

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