Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.

scientific article published on 13 October 2013

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1052269583
P356DOI10.1038/NATURE12595
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/nature12595
P698PubMed publication ID24121438

P50authorArthur ChristopoulosQ18977850
Meritxell CanalsQ46120848
James R ValcourtQ56938571
Celine ValantQ56938593
Ron Ofer DrorQ59678272
Raphael RahmaniQ63509783
J. Robert LaneQ63923479
Jonathan B BaellQ87721461
Patrick M. SextonQ39936838
David W. BorhaniQ42390809
P2093author name stringDavid E Shaw
Albert C Pan
Daniel H Arlow
Hillary F Green
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Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.Q37773544
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How does a drug molecule find its target binding site?Q39280041
Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors.Q42277559
How robust are protein folding simulations with respect to force field parameterization?Q42853031
Analogs of WIN 62,577 define a second allosteric site on muscarinic receptorsQ44219305
Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-oQ44483391
Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptorsQ44483424
Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptorsQ44719359
P433issue7475
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P1104number of pages5
P304page(s)295-299
P577publication date2013-10-13
P1433published inNatureQ180445
P1476titleStructural basis for modulation of a G-protein-coupled receptor by allosteric drugs
P478volume503

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