scholarly article | Q13442814 |
P2093 | author name string | André Nussenzweig | |
Paul Meltzer | |||
Anthony Tubbs | |||
Barry P Sleckman | |||
Andres Canela | |||
Nicholas Sciascia | |||
Sriram Sridharan | |||
P2860 | cites work | The DNA-damage response in human biology and disease | Q24606586 |
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities | Q24617969 | ||
The human genome browser at UCSC | Q24672361 | ||
Identification and utilization of arbitrary correlations in models of recombination signal sequences | Q24803178 | ||
Fast gapped-read alignment with Bowtie 2 | Q27860699 | ||
The Sequence Alignment/Map format and SAMtools | Q27860966 | ||
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1 | Q27938100 | ||
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX | Q28139663 | ||
The RAG proteins and V(D)J recombination: complexes, ends, and transposition | Q28145648 | ||
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV | Q28235281 | ||
V(D)J recombination: mechanisms of initiation | Q28245998 | ||
The response to and repair of RAG-mediated DNA double-strand breaks | Q28256889 | ||
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments | Q28259020 | ||
Zinc-finger nucleases: the next generation emerges | Q28283445 | ||
Recombination centres and the orchestration of V(D)J recombination | Q28307066 | ||
Enhancer repertoires are reshaped independently of early priming and heterochromatin dynamics during B cell differentiation | Q28607796 | ||
BEDTools: a flexible suite of utilities for comparing genomic features | Q29547332 | ||
RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription | Q30740300 | ||
ATM prevents the persistence and propagation of chromosome breaks in lymphocytes | Q33289263 | ||
A clustering approach for identification of enriched domains from histone modification ChIP-Seq data | Q33464035 | ||
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation | Q33691942 | ||
The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci. | Q33889784 | ||
Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes | Q33925876 | ||
In vivo genome editing using Staphylococcus aureus Cas9 | Q34043628 | ||
DNA break mapping reveals topoisomerase II activity genome-wide | Q34072605 | ||
CRISPR-mediated direct mutation of cancer genes in the mouse liver | Q34353586 | ||
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases | Q34454104 | ||
Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes | Q34479605 | ||
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle | Q34537165 | ||
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. | Q34541828 | ||
HCoDES reveals chromosomal DNA end structures with single-nucleotide resolution | Q34747083 | ||
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases. | Q35060760 | ||
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9 | Q35820051 | ||
RAG Represents a Widespread Threat to the Lymphocyte Genome | Q35958144 | ||
Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing | Q35975147 | ||
Histone reader BRWD1 targets and restricts recombination to the Igk locus. | Q36074413 | ||
New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors | Q36179241 | ||
Transcriptional elongation requires DNA break-induced signalling | Q36438053 | ||
Cryptic signals and the fidelity of V(D)J joining | Q36568596 | ||
Restoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining | Q36706287 | ||
Identification of early replicating fragile sites that contribute to genome instability | Q36776345 | ||
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing | Q36834533 | ||
Nucleosomes impede Cas9 access to DNA in vivo and in vitro | Q36885171 | ||
Unifying model for molecular determinants of the preselection Vβ repertoire | Q37117734 | ||
Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus | Q37384044 | ||
End-joining, translocations and cancer | Q38113932 | ||
Non-homologous end joining often uses microhomology: implications for alternative end joining | Q38194755 | ||
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia | Q38367298 | ||
Regulation and Evolution of the RAG Recombinase | Q38610190 | ||
Chromatin Dynamics and the Development of the TCRα and TCRδ Repertoires | Q38610203 | ||
Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases | Q38810667 | ||
An unbiased genome-wide analysis of zinc-finger nuclease specificity | Q39493921 | ||
Estrogen receptor α-mediated transcription induces cell cycle-dependent DNA double-strand breaks | Q39626579 | ||
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. | Q39719766 | ||
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. | Q40263593 | ||
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements | Q41823310 | ||
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes. | Q41998609 | ||
Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated | Q64389767 | ||
V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals | Q64389915 | ||
Relationship between DNA damage and survival in formaldehyde-treated mouse cells | Q70736460 | ||
The V(D)J recombinase efficiently cleaves and transposes signal joints | Q78025745 | ||
P433 | issue | 5 | |
P304 | page(s) | 898-911 | |
P577 | publication date | 2016-07-28 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | DNA Breaks and End Resection Measured Genome-wide by End Sequencing | |
P478 | volume | 63 |
Q92378292 | A Practical Guide to Genome Editing Using Targeted Nuclease Technologies |
Q38701755 | A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks |
Q42176298 | A global view of meiotic double-strand break end resection |
Q89948847 | A novel NGS library preparation method to characterize native termini of fragmented DNA |
Q89686193 | ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis |
Q47978403 | Anchoring Chromatin Loops to Cancer |
Q93160539 | BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks |
Q33705629 | BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks |
Q90722627 | Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility |
Q92500894 | CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution |
Q58553471 | Common fragile site instability in normal cells: lessons and perspectives |
Q64071396 | Cut-and-Run: A Distinct Mechanism by which V(D)J Recombination Causes Genome Instability |
Q92543190 | DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II |
Q58591000 | Deciphering phenotypic variance in different models of DNA-PKcs deficiency |
Q64230079 | Deficiency of the Fanconi anemia E2 ubiqitin conjugase UBE2T only partially abrogates Alu-mediated recombination in a new model of homology dependent recombination |
Q57810989 | Defining CRISPR-Cas9 genome-wide nuclease activities with CIRCLE-seq |
Q64889763 | Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse. |
Q39130435 | Endogenous DNA Damage as a Source of Genomic Instability in Cancer |
Q60955054 | Endogenous DNA Double-Strand Breaks during DNA Transactions: Emerging Insights and Methods for Genome-Wide Profiling |
Q89723258 | Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency |
Q47102607 | Generation and CRISPR/Cas9 editing of transformed progenitor B cells as a pseudo-physiological system to study DNA repair gene function in V(D)J recombination. |
Q38696563 | Genome Organization Drives Chromosome Fragility |
Q50086294 | Genome-Wide Profiling of DNA Double-Strand Breaks by the BLESS and BLISS Methods |
Q47590940 | Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments |
Q101166878 | Genome-wide detection of DNA double-strand breaks by in-suspension BLISS |
Q96610109 | Genome-wide high-resolution mapping of mitotic DNA synthesis sites and common fragile sites by direct sequencing |
Q95300387 | Hypermutation in single-stranded DNA |
Q90402550 | ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing |
Q37654501 | Lineage-Specific Genes Are Prominent DNA Damage Hotspots during Leukemic Transformation of B Cell Precursors |
Q90314589 | Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development |
Q50086287 | Mapping DNA Breaks by Next-Generation Sequencing |
Q92663919 | Mapping DNA Topoisomerase Binding and Cleavage Genome Wide Using Next-Generation Sequencing Techniques |
Q89825438 | Methodologies for detecting environmentally induced DNA damage and repair |
Q55147779 | Modeling cancer rearrangement landscapes. |
Q61797380 | Modeling double strand break susceptibility to interrogate structural variation in cancer |
Q39225472 | New traits in crops produced by genome editing techniques based on deletions |
Q58797497 | Patterns and mechanisms of structural variations in human cancer |
Q52653703 | Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution. |
Q91767877 | RAG-2 deficiency results in fewer phosphorylated histone H2AX foci, but increased retinal ganglion cell death and altered axonal growth |
Q49557385 | Radiation-induced unrepairable DSBs: their role in the late effects of radiation and possible applications to biodosimetry |
Q64386891 | Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations |
Q90375281 | Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation |
Q100395415 | Repeat expansions confer WRN dependence in microsatellite-unstable cancers |
Q57753966 | Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements |
Q90182031 | Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox |
Q89711422 | Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity |
Q39441711 | The ATM Kinase Restrains Joining of Both VDJ Signal and Coding Ends. |
Q92107013 | The ESC: The Dangerous By-Product of V(D)J Recombination |
Q92544102 | The Secret Life of Chromosome Loops upon DNA Double-Strand Break |
Q64387109 | The genome-wide sequence preference of ionising radiation-induced cleavage in human DNA |
Q52723355 | The response to DNA damage in heterochromatin domains. |
Q58582945 | i-BLESS is an ultra-sensitive method for detection of DNA double-strand breaks |
Q39111656 | p53 and RAD9, the DNA Damage Response, and Regulation of Transcription Networks |
Q64283651 | qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing |
Search more.