| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/BIT.24858 |
| P698 | PubMed publication ID | 23381838 |
| P2093 | author name string | Jamey D Young | |
| Jason Dean | |||
| Pranhitha Reddy | |||
| Neil Templeton | |||
| P2860 | cites work | Understanding the Warburg effect: the metabolic requirements of cell proliferation | Q24604760 |
| The biology of cancer: metabolic reprogramming fuels cell growth and proliferation | Q29547301 | ||
| Cytoscape 2.8: new features for data integration and network visualization | Q29547471 | ||
| Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis | Q29617613 | ||
| Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells | Q34517790 | ||
| ROS, mitochondria and the regulation of autophagy | Q34679713 | ||
| Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt | Q34778767 | ||
| Metabolic networks in motion: 13C-based flux analysis | Q35194034 | ||
| The role of glutathione in disulphide bond formation and endoplasmic-reticulum-generated oxidative stress. | Q36445293 | ||
| Glucose metabolism and cancer | Q36625786 | ||
| Metabolic flux analysis in mammalian cell culture | Q37615599 | ||
| Towards dynamic metabolic flux analysis in CHO cell cultures | Q37958819 | ||
| Metabolic analysis of antibody producing CHO cells in fed-batch production | Q39214774 | ||
| Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry | Q39494168 | ||
| Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture | Q39880044 | ||
| Antibody production | Q40258663 | ||
| Considerations on the lactate consumption by CHO cells in the presence of galactose | Q40258669 | ||
| Impact of temperature reduction and expression of yeast pyruvate carboxylase on hGM-CSF-producing CHO cells | Q40570353 | ||
| Elementary metabolite units (EMU): a novel framework for modeling isotopic distributions | Q41374953 | ||
| Influence of ammonium on growth, metabolism, and productivity of a continuous suspension Chinese hamster ovary cell culture | Q41505216 | ||
| Chemical decomposition of glutamine in cell culture media: effect of media type, pH, and serum concentration | Q41743417 | ||
| Modeling hybridoma cell metabolism using a generic genome-scale metabolic model of Mus musculus | Q42657070 | ||
| Towards quantitative metabolomics of mammalian cells: development of a metabolite extraction protocol | Q43077487 | ||
| Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy | Q43246624 | ||
| Dynamic model of CHO cell metabolism. | Q43711578 | ||
| Oxidative stress in cell culture: an under-appreciated problem? | Q44394239 | ||
| Strategies for fed-batch cultivation of t-PA producing CHO cells: substitution of glucose and glutamine and rational design of culture medium | Q44879306 | ||
| Feeding lactate for CHO cell culture processes: impact on culture metabolism and performance | Q45196969 | ||
| Error propagation from prime variables into specific rates and metabolic fluxes for mammalian cells in perfusion culture. | Q45955314 | ||
| Effective quenching processes for physiologically valid metabolite profiling of suspension cultured Mammalian cells | Q46211106 | ||
| Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements. | Q51220949 | ||
| Metabolic flux analysis of CHO cell metabolism in the late non-growth phase. | Q51772488 | ||
| Towards a metabolic and isotopic steady state in CHO batch cultures for reliable isotope-based metabolic profiling. | Q51781767 | ||
| Bidirectional reaction steps in metabolic networks: IV. Optimal design of isotopomer labeling experiments. | Q52136732 | ||
| Metabolite-balancing techniques vs. 13C tracer experiments to determine metabolic fluxes in hybridoma cells. | Q52219118 | ||
| Mathematical descriptions of hybridoma culture kinetics: I. Initial metabolic rates. | Q52426515 | ||
| Cell biology. Warburg effect and redox balance. | Q54545217 | ||
| P433 | issue | 7 | |
| P921 | main subject | antibody | Q79460 |
| P304 | page(s) | 2013-2024 | |
| P577 | publication date | 2013-03-04 | |
| P1433 | published in | Biotechnology and Bioengineering | Q4915339 |
| P1476 | title | Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture. | |
| P478 | volume | 110 |
| Q47628994 | 13C metabolic flux analysis identifies limitations to increasing specific productivity in fed-batch and perfusion |
| Q38729154 | A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. |
| Q35762155 | A Single Dynamic Metabolic Model Can Describe mAb Producing CHO Cell Batch and Fed-Batch Cultures on Different Culture Media |
| Q38791462 | A control strategy to investigate the relationship between specific productivity and high-mannose glycoforms in CHO cells |
| Q51743451 | A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture. |
| Q42875887 | A novel approach for using dielectric spectroscopy to predict viable cell volume (VCV) in early process development |
| Q35121927 | Analyzing clonal variation of monoclonal antibody-producing CHO cell lines using an in silico metabolomic platform |
| Q51029178 | Application of 13C flux analysis to identify high-productivity CHO metabolic phenotypes. |
| Q56886814 | Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process |
| Q53157361 | Closed loop control of lactate concentration in mammalian cell culture by Raman spectroscopy leads to improved cell density, viability, and biopharmaceutical protein production. |
| Q31001923 | Combining mechanistic and data-driven approaches to gain process knowledge on the control of the metabolic shift to lactate uptake in a fed-batch CHO process. |
| Q51741966 | Compartment-specific metabolomics for CHO reveals that ATP pools in mitochondria are much lower than in cytosol. |
| Q35568915 | Cyclin and DNA distributed cell cycle model for GS-NS0 cells |
| Q35962616 | Effect of Temperature Downshift on the Transcriptomic Responses of Chinese Hamster Ovary Cells Using Recombinant Human Tissue Plasminogen Activator Production Culture |
| Q97094598 | Elevated pCO2 affects the lactate metabolic shift in CHO cell culture processes |
| Q51749427 | Elucidating the effects of postinduction glutamine feeding on the growth and productivity of CHO cells. |
| Q51742400 | Elucidating the role of copper in CHO cell energy metabolism using (13)C metabolic flux analysis. |
| Q51333626 | Evidence for transketolase-like TKTL1 flux in CHO cells based on parallel labeling experiments and (13)C-metabolic flux analysis. |
| Q92728754 | From nutritional wealth to autophagy: In vivo metabolic dynamics in the cytosol, mitochondrion and shuttles of IgG producing CHO cells |
| Q92380845 | Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion |
| Q64969191 | High extracellular lactate causes reductive carboxylation in breast tissue cell lines grown under normoxic conditions. |
| Q51590229 | Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells. |
| Q53443562 | Identifying Biomarkers of Wharton's Jelly Mesenchymal Stromal Cells Using a Dynamic Metabolic Model: The Cell Passage Effect. |
| Q89833681 | Improvements in protein production in mammalian cells from targeted metabolic engineering |
| Q51284751 | Improving lactate metabolism in an intensified CHO culture process: productivity and product quality considerations. |
| Q47642543 | Intracellular response to process optimization and impact on productivity and product aggregates for a high-titer CHO cell process. |
| Q38709176 | Low glucose concentrations within typical industrial operating conditions have minimal effect on the transcriptome of recombinant CHO cells |
| Q46021617 | Mannose metabolism in recombinant CHO cells and its effect on IgG glycosylation. |
| Q41704579 | Metabolic Control in Mammalian Fed-Batch Cell Cultures for Reduced Lactic Acid Accumulation and Improved Process Robustness |
| Q47139496 | Metabolic characterization of a CHO cell size increase phase in fed-batch cultures |
| Q41200443 | Metabolic engineering of CHO cells for the development of a robust protein production platform. |
| Q38111036 | Metabolic flux rewiring in mammalian cell cultures |
| Q47401579 | Metabolic phenotyping of CHO cells varying in cellular biomass accumulation and maintenance during fed-batch culture |
| Q51749039 | Metabolic responses of CHO cells to limitation of key amino acids. |
| Q39398074 | Metabolic signatures of GS-CHO cell clones associated with butyrate treatment and culture phase transition |
| Q38850597 | Metabolite profiling of CHO cells: Molecular reflections of bioprocessing effectiveness |
| Q90321698 | Multi-Omics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism and Specific Productivity in CHO Cell Bioprocessing |
| Q35585969 | Multiplicity of steady states in glycolysis and shift of metabolic state in cultured mammalian cells |
| Q35158693 | Non-stationary 13C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation |
| Q41323190 | Novel Cell-Ess ® supplement used as a feed or as an initial boost to CHO serum free media results in a significant increase in protein yield and production |
| Q91784105 | Oxidative stress-alleviating strategies to improve recombinant protein production in CHO cells |
| Q50046582 | Quantitative analysis of glycation and its impact on antigen binding. |
| Q51742404 | Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. |
| Q38721175 | Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion |
| Q64054620 | The Less the Better: How Suppressed Base Addition Boosts Production of Monoclonal Antibodies With Chinese Hamster Ovary Cells |
| Q51747773 | The impact of anti-apoptotic gene Bcl-2∆ expression on CHO central metabolism. |
| Q39203339 | The role of metabolic states in development and disease. |
| Q38522584 | The use of 'Omics technology to rationally improve industrial mammalian cell line performance |
| Q38716834 | Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells |
| Q42114501 | Universal Capacitance Model for Real-Time Biomass in Cell Culture. |
| Q42049559 | Using simple models to describe the kinetics of growth, glucose consumption, and monoclonal antibody formation in naive and infliximab producer CHO cells. |
| Q38947322 | What can mathematical modelling say about CHO metabolism and protein glycosylation? |
| Q38713547 | miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development. |
Search more.