| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M408985200 |
| P698 | PubMed publication ID | 15598661 |
| P50 | author | Ralph A. DeFronzo | Q58689309 |
| Lawrence J Mandarino | Q91188766 | ||
| P2093 | author name string | Kenneth Cusi | |
| Mandeep Bajaj | |||
| Christopher P Jenkinson | |||
| Jean Finlayson | |||
| Sangeeta Kashyap | |||
| Dawn K Richardson | |||
| Steven J Mandarino | |||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | molecular biology | Q7202 |
| cell biology | Q7141 | ||
| mitochondrion | Q39572 | ||
| P304 | page(s) | 10290-10297 | |
| P577 | publication date | 2004-12-14 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle | |
| P478 | volume | 280 |
| Q51027096 | Abnormal lipid metabolism down-regulates adenosine triphosphate synthase β-subunit protein expression in corpus cavernosum smooth muscle in vitro and in vivo. |
| Q43074217 | Acute elevation of plasma lipids does not affect ATP synthesis in human skeletal muscle |
| Q33918445 | Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes |
| Q88571046 | Alpha-linolenic acid and linoleic acid differentially regulate the skeletal muscle secretome of obese Zucker rats |
| Q37141727 | Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus |
| Q90254735 | CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high-fat-fed C57BL/6 mice |
| Q36102736 | Changes in Pre- and Post-Exercise Gene Expression among Patients with Chronic Kidney Disease and Kidney Transplant Recipients |
| Q46337001 | Changes in microvascular density differentiate metabolic health outcomes in monkeys with prior radiation exposure and subsequent skeletal muscle ECM remodeling |
| Q64355580 | Chapter 12 Regulation of PGC-1 in humans with insulin resistance and type 2 diabetes: Functional implications |
| Q37332538 | Characterization of the human skeletal muscle proteome by one-dimensional gel electrophoresis and HPLC-ESI-MS/MS. |
| Q34152435 | Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts. |
| Q51480723 | Chronological approach of diet-induced alterations in muscle mitochondrial functions in rats. |
| Q38171244 | Clinical biomarkers in metabolic syndrome |
| Q37934748 | Crosstalk between mitochondrial (dys)function and mitochondrial abundance |
| Q37738735 | Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus |
| Q46507502 | Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance |
| Q34526996 | Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice |
| Q33752866 | Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes |
| Q36764954 | ESCI Award 2006. Mitochondrial function and endocrine diseases |
| Q33747784 | Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study |
| Q36635727 | Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo |
| Q33586726 | Effect of short-term free Fatty acids elevation on mitochondrial function in skeletal muscle of healthy individuals |
| Q37295284 | Enforced expression of protein kinase C in skeletal muscle causes physical inactivity, fatty liver and insulin resistance in the brain |
| Q28269790 | Fatty acid-induced differential regulation of the genes encoding peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in human skeletal muscle cells that have been differentiated in vitro |
| Q36560945 | Fatty acid-induced inflammation and insulin resistance in skeletal muscle and liver |
| Q36879537 | Fibre type dependent expression of glucose transporters in human skeletal muscles |
| Q58554975 | Fibro-Adipogenic Remodeling of the Diaphragm in Obesity-Associated Respiratory Dysfunction |
| Q35620492 | Gene and MicroRNA Expression Responses to Exercise; Relationship with Insulin Sensitivity |
| Q95279361 | Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet-induced obesity |
| Q37371168 | Global relationship between the proteome and transcriptome of human skeletal muscle |
| Q36322951 | Growth hormone replacement therapy regulates microRNA-29a and targets involved in insulin resistance |
| Q34090974 | High fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance |
| Q34600082 | Hypermethylation of Cox5a promoter is associated with mitochondrial dysfunction in skeletal muscle of high fat diet-induced insulin resistant rats |
| Q46259240 | Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals |
| Q30514207 | Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes |
| Q55162946 | Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus |
| Q34627092 | Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance |
| Q48376266 | Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects |
| Q33976122 | Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet |
| Q36408698 | Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases |
| Q49349613 | Insulin resistance in obesity: an overview of fundamental alterations |
| Q33880303 | Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009 |
| Q46752019 | Inverse relationship between PGC-1alpha protein expression and triacylglycerol accumulation in rodent skeletal muscle |
| Q37505520 | Lessons learned from studying families genetically predisposed to type 2 diabetes mellitus |
| Q33729970 | Long-lasting effect of obesity on skeletal muscle transcriptome |
| Q41881288 | MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice |
| Q34138756 | Matrix metalloproteinase 9 opposes diet-induced muscle insulin resistance in mice |
| Q91809789 | Metabolomics Analysis of Skeletal Muscles from FKRP-Deficient Mice Indicates Improvement After Gene Replacement Therapy |
| Q37612965 | Mitochondria and diabetes mellitus: untangling a conflictive relationship? |
| Q64068197 | Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet |
| Q34511749 | Mitochondrial dynamics in diabetes |
| Q91179582 | Mitochondrial dynamics in skeletal muscle insulin resistance and type 2 diabetes |
| Q35543642 | Mitochondrial dysfunction and insulin resistance from the outside in: extracellular matrix, the cytoskeleton, and mitochondria |
| Q38586903 | Mitochondrial dysfunction in diabetic neuropathy: a series of unfortunate metabolic events. |
| Q37210859 | Mitochondrial dysfunction in obesity |
| Q37215415 | Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitus |
| Q55162945 | Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding |
| Q36953482 | Mitochondrial plasticity in obesity and diabetes mellitus |
| Q89719465 | Multi-Tissue DNA Methylation Remodeling at Mitochondrial Quality Control Genes According to Diet in Rat Aging Models |
| Q58702059 | Multifaceted Interweaving Between Extracellular Matrix, Insulin Resistance, and Skeletal Muscle |
| Q90550258 | Muscarinic Toxin 7 Signals Via Ca2+/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration |
| Q33283340 | Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes |
| Q36356864 | Muscle triglycerides and mitochondrial function: possible mechanisms for the development of type 2 diabetes |
| Q30008893 | Next-generation sequencing methylation profiling of subjects with obesity identifies novel gene changes |
| Q28385506 | Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes |
| Q34269093 | Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans |
| Q37346326 | PGC-1alpha in aging and anti-aging interventions |
| Q33305208 | PGC-1alpha inhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells |
| Q30431199 | PGC-1alpha regulation by exercise training and its influences on muscle function and insulin sensitivity |
| Q37412140 | PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure |
| Q37485965 | PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity |
| Q37299286 | PGC-1alpha-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptions |
| Q28244126 | PGC-1alpha: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes |
| Q37299866 | Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity |
| Q33812448 | Pathogenesis of insulin resistance in skeletal muscle |
| Q34137628 | Pathological aspects of lipid peroxidation. |
| Q50725628 | Peroxisome proliferator-activated receptor-gamma coactivator-1 and insulin resistance: acute effect of fatty acids. |
| Q35997389 | Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy |
| Q36972810 | Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial |
| Q52745102 | Potential epigenetic biomarkers of obesity-related insulin resistance in human whole-blood. |
| Q37143194 | Potential mechanisms of muscle mitochondrial dysfunction in aging and obesity and cellular consequences |
| Q33556644 | Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes |
| Q35973475 | Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle. |
| Q40191018 | Reduced plasma free fatty acid availability during exercise: effect on gene expression. |
| Q34110159 | Reduction in inflammatory gene expression in skeletal muscle from Roux-en-Y gastric bypass patients randomized to omentectomy |
| Q38884586 | Rosiglitazone, but not epigallocatechin-3-gallate, attenuates the decrease in PGC-1α protein levels in palmitate-induced insulin-resistant C2C12 cells |
| Q36169626 | SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease |
| Q36382552 | Secondary muscle pathology and metabolic dysregulation in adults with cerebral palsy |
| Q33624769 | Skeletal Muscle Nucleo-Mitochondrial Crosstalk in Obesity and Type 2 Diabetes. |
| Q37463518 | Skeletal muscle insulin resistance: the interplay of local lipid excess and mitochondrial dysfunction. |
| Q47107979 | Swimming training alleviated insulin resistance through Wnt3a/β-catenin signaling in type 2 diabetic rats |
| Q45462968 | The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues. |
| Q36642598 | The Ups and Downs of Insulin Resistance and Type 2 Diabetes: Lessons from Genomic Analyses in Humans |
| Q51311315 | The effect of muraglitazar on adiponectin signalling, mitochondrial function and fat oxidation genes in human skeletal muscle in vivo. |
| Q39285273 | The emerging role of skeletal muscle extracellular matrix remodelling in obesity and exercise |
| Q35812133 | The extracellular matrix and insulin resistance |
| Q41433276 | The physiological regulation of glucose flux into muscle in vivo |
| Q37765850 | The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes |
| Q37930956 | The role of mitochondria in insulin resistance and type 2 diabetes mellitus |
| Q36003367 | The role of mitochondria in the pathogenesis of type 2 diabetes |
| Q33779662 | The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance |
| Q42440646 | Transcriptional profiling of myotubes from patients with type 2 diabetes: no evidence for a primary defect in oxidative phosphorylation genes |
| Q35242951 | Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES) |
| Q40945511 | Treatment of hyaluronan accumulation ameliorates high-fat diet-induced insulin resistance in mice |
| Q33568954 | Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling |
| Q35073216 | Whole blood gene expression profiles in insulin resistant Latinos with the metabolic syndrome |
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