human | Q5 |
P269 | IdRef ID | 223952923 |
P213 | ISNI | 0000000026475283 |
P496 | ORCID iD | 0000-0002-4769-6311 |
P214 | VIAF ID | 24822370 |
P735 | given name | David | Q18057751 |
David | Q18057751 | ||
P106 | occupation | researcher | Q1650915 |
P5008 | on focus list of Wikimedia project | WikiProject COVID-19 | Q87748614 |
P21 | sex or gender | male | Q6581097 |
Q73709074 | A VH11V kappa 9 B cell antigen receptor drives generation of CD5+ B cells both in vivo and in vitro |
Q73535809 | A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors |
Q100387966 | A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody |
Q37220784 | A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes. |
Q78233407 | Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse |
Q102380766 | An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19 |
Q36402702 | An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system |
Q71197127 | Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes |
Q41136316 | Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies. |
Q37316819 | Antigen receptor 'capacity' and the sensitivity of self-tolerance. |
Q35084274 | Antigen receptor selection by editing or downregulation of V(D)J recombination. |
Q36404230 | Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses. |
Q104111171 | Author Correction: Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells |
Q35160339 | B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection. |
Q37220772 | B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice |
Q36367608 | B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen. |
Q98890585 | B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models |
Q37171260 | B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates |
Q68011961 | B lymphocytes from the autoimmune-prone mouse strain MLR/lpr manifest an intrinsic defect in tetraparental MRL/lpr in equilibrium DBA/2 chimeras |
Q37183404 | Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection. |
Q96429124 | Broad neutralization of SARS-related viruses by human monoclonal antibodies |
Q112715402 | Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors |
Q59098044 | Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes |
Q57198265 | Contribution of Receptor Editing to the Antibody Repertoire |
Q33615157 | Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo |
Q55313333 | Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo. |
Q36811047 | Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice. |
Q24309087 | DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF |
Q41611835 | Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. |
Q92184345 | Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes |
Q52190945 | Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection. |
Q36375334 | Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells. |
Q71556149 | Does immunological tolerance explain the waste in the B-lymphocyte immune system? Experiment and theory |
Q82704548 | Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B-1 cell survival in transgenic mice expressing a low level of Igkappa-reactive macroself antigen |
Q36404207 | Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes |
Q46493549 | Engineered mice and B cell lines expressing broadly neutralizing antibodies and their unmutated precursors: tools for HIV vaccinology. |
Q36300341 | Enhancing antibody: a novel component of the immune response. |
Q24652635 | FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles |
Q57222709 | Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice |
Q40053462 | Generation of T-follicular helper cells in vitro: requirement for BCR cross-linking and cognate B- and T-cell interaction. |
Q36345558 | HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. |
Q59339672 | HIV-1 vaccine design through minimizing envelope metastability |
Q36957800 | High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells. |
Q41870758 | Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice. |
Q34494308 | Immunoglobulin transgenes in B lymphocyte development, tolerance, and autoimmunity. |
Q68126711 | Inability of IL-2 and IL-10 to counteract B cell clonal deletion |
Q36348899 | Induction of rheumatoid antibodies in the mouse. Regulated production of autoantibody in the secondary humoral response |
Q96429194 | Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model |
Q34681437 | Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing. |
Q36325225 | Mechanisms and meaning of B-lymphocyte tolerance. |
Q39214736 | Mechanisms of central tolerance for B cells. |
Q35582239 | Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape |
Q90967071 | PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing |
Q54593961 | Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice. |
Q33869858 | Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen. |
Q35915043 | Peripheral B lymphocyte tolerance. |
Q47232975 | Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens |
Q37060947 | Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles |
Q40809007 | Promotion and prevention of autoimmunity by B lymphocytes. |
Q46987046 | Rational immunogen design to target specific germline B cell receptors |
Q36455313 | Receptor editing and genetic variability in human autoreactive B cells. |
Q36399448 | Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A |
Q34568574 | Receptor editing in lymphocyte development and central tolerance. |
Q37220764 | Receptor editing in self-reactive bone marrow B cells. The Journal of Experimental Medicine. 1993. 177: 1009-1020. |
Q36401586 | Receptor editing occurs frequently during normal B cell development. |
Q33743324 | Receptor editing: genetic reprogramming of autoreactive lymphocytes. |
Q37153957 | Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs |
Q35686885 | Regulation of the B cell receptor repertoire and self-reactivity by BAFF |
Q36751836 | Role of RS/kappaDE in B cell receptor editing. |
Q34338742 | Role of receptor editing and revision in shaping the B and T lymphocyte repertoire. |
Q36562230 | Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest. |
Q35784452 | Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing. |
Q98467301 | Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate |
Q100750028 | Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate |
Q98384046 | Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens |
Q37246321 | Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies |
Q59488222 | Targeting cytotoxic T cells to antigen-specific B lymphocytes |
Q46490359 | The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection. |
Q36659226 | The design and implementation of the immune epitope database and analysis resource |
Q24804461 | The immune epitope database and analysis resource: from vision to blueprint |
Q35930798 | The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity. |
Q41711151 | Theoretical limits to massive receptor editing in immature B cells. |
Q35666716 | Tolerance-induced receptor selection: scope, sensitivity, locus specificity, and relationship to lymphocyte-positive selection. |
Q73086202 | Unexpected autoantibody production in membrane Ig-mu-deficient/lpr mice |
Q56687402 | V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses |
Q102141512 | Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells |
Q36353493 | Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization. |
Search more.