| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/HMG/DDG146 |
| P698 | PubMed publication ID | 12761036 |
| P50 | author | Clemens O. Hanemann | Q46766795 |
| P2093 | author name string | Tamara Utermark | |
| Sonja Langmesser | |||
| Kirsten Mielke | |||
| Katherine Kaempchen | |||
| P433 | issue | 11 | |
| P304 | page(s) | 1211-1221 | |
| P577 | publication date | 2003-06-01 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells | |
| P478 | volume | 12 |
| Q24299493 | A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions |
| Q30464276 | AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas |
| Q50879137 | An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis. |
| Q46412577 | Axl/Gas6/NFκB signalling in schwannoma pathological proliferation, adhesion and survival. |
| Q28756758 | Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination |
| Q90899097 | Brazilein induces apoptosis and G1/G0 phase cell cycle arrest by up-regulation of miR-133a in human vestibular schwannoma cells |
| Q53316010 | Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis. |
| Q64927814 | Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas. |
| Q50741619 | Constitutive neuregulin-1/ErbB signaling contributes to human vestibular schwannoma proliferation. |
| Q30464280 | Contribution of persistent C-Jun N-terminal kinase activity to the survival of human vestibular schwannoma cells by suppression of accumulation of mitochondrial superoxides. |
| Q89104578 | Deregulation of the Hippo Pathway Promotes Tumor Cell Proliferation Through YAP Activity in Human Sporadic Vestibular Schwannoma |
| Q37715015 | Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer |
| Q30474678 | ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma |
| Q27679769 | FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas |
| Q45076806 | Forskolin increases neuregulin receptors in human Schwann cells without increasing receptor mRNA. |
| Q33809716 | Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target. |
| Q40171646 | HEI10 negatively regulates cell invasion by inhibiting cyclin B/Cdk1 and other promotility proteins |
| Q46778652 | Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells |
| Q40534803 | Inhibiting p21-Activated Kinase Induces Cell Death in Vestibular Schwannoma and Meningioma via Mitotic Catastrophe |
| Q35049697 | Inhibition of Cdc42-mediated activation of mixed lineage kinase 3 by the tumor suppressor protein merlin |
| Q30419586 | Inhibition of c-Jun N-terminal kinase activity enhances vestibular schwannoma cell sensitivity to gamma irradiation. |
| Q42493873 | Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival. |
| Q30489292 | Laminin is required for Schwann cell morphogenesis |
| Q30458195 | Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells |
| Q35777641 | Merlin and the ERM proteins in Schwann cells, neurons and growth cones |
| Q34620864 | Merlin's tumor suppression linked to inhibition of the E3 ubiquitin ligase CRL4 (DCAF1) |
| Q35670477 | Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways |
| Q35836025 | Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism |
| Q24300692 | Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus |
| Q35880377 | Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus. |
| Q38327730 | Microarray-based copy number analysis of neurofibromatosis type-1 (NF1)-associated malignant peripheral nerve sheath tumors reveals a role for Rho-GTPase pathway genes in NF1 tumorigenesis |
| Q33787331 | Mitogen Activated Protein Kinase Family Proteins and c-jun Signaling in Injury-induced Schwann Cell Plasticity |
| Q36494071 | Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth |
| Q39162513 | Molecular Mechanisms Involved in Schwann Cell Plasticity |
| Q38204110 | Molecular insights into NF2/Merlin tumor suppressor function |
| Q36821586 | N-cadherin expression is regulated by UTP in schwannoma cells. |
| Q33818953 | NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation |
| Q46902773 | Neuregulin and laminin stimulate phosphorylation of the NF2 tumor suppressor in Schwann cells by distinct protein kinase A and p21-activated kinase-dependent pathways |
| Q26825296 | Neurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator |
| Q28283074 | News on the genetics, epidemiology, medical care and translational research of Schwannomas |
| Q39512836 | Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2. |
| Q30490902 | PAK kinase regulates Rac GTPase and is a potential target in human schwannomas |
| Q33944254 | Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα. |
| Q34062012 | Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas |
| Q38455974 | Rac1 controls Schwann cell myelination through cAMP and NF2/merlin |
| Q41977319 | Rac1 is required for Prkar1a-mediated Nf2 suppression in Schwann cell tumors |
| Q41073081 | Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. |
| Q36189820 | Role of Merlin/NF2 inactivation in tumor biology |
| Q99603543 | Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling |
| Q30502106 | Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length |
| Q83005031 | Temporal control of Rac in Schwann cell-axon interaction is disrupted in NF2-mutant schwannoma cells |
| Q30487287 | The ErbB inhibitors trastuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary study |
| Q30606515 | The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway |
| Q39179290 | The Neuregulin-Rac-MKK7 pathway regulates antagonistic c-jun/Krox20 expression in Schwann cell dedifferentiation |
| Q51855737 | The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. |
| Q37040608 | The function of RhoGTPases in axon ensheathment and myelination |
| Q30467803 | The molecular biology of vestibular schwannomas and its association with hearing loss: a review. |
| Q41135859 | The p53/mouse double minute 2 homolog complex deregulation in merlin-deficient tumours |
| Q42509945 | The role of insulin-like growth factors signaling in merlin-deficient human schwannomas. |
| Q24672036 | Up-regulation of Rac1 by epidermal growth factor mediates COX-2 expression in recurrent respiratory papillomas |
| Q33721426 | Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation |
| Q40040209 | Validation of the p21-activated kinases as targets for inhibition in neurofibromatosis type 2. |
| Q91823921 | YAP/TAZ Inhibition Induces Metabolic and Signaling Rewiring Resulting in Targetable Vulnerabilities in NF2-Deficient Tumor Cells |
| Q30401833 | p75NTR is highly expressed in vestibular schwannomas and promotes cell survival by activating nuclear transcription factor κB. |
Search more.