p53-dependent pathways of apoptosis

scientific article published on 01 November 2001

p53-dependent pathways of apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.CDD.4400918
P953full work available online athttp://www.nature.com/articles/4400918
http://www.nature.com/articles/4400918.pdf
P698PubMed publication ID11687883

P2093author name stringS. Benchimol
P2860cites workGADD45 induction of a G2/M cell cycle checkpointQ22009111
ei24, a p53 response gene involved in growth suppression and apoptosisQ22010923
LRDD, a novel leucine rich repeat and death domain containing proteinQ22254132
Mediation of c-Myc-induced apoptosis by p53.Q41441186
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genesQ41454039
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.Q41563742
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosisQ41563751
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.Q41723055
A transactivation-deficient mouse model provides insights into Trp53 regulation and functionQ41759568
Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in miceQ42484376
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibitionQ53425055
Induction of apoptosis in HeLa cells by trans-activation-deficient p53Q53461564
Transcriptional activation by p53 correlates with suppression of growth but not transformationQ53468212
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cellsQ71618789
p53-dependent apoptosis suppresses tumor growth and progression in vivoQ72149266
The tumor suppressor protein p53 requires a cofactor to activate transcriptionally the human BAX promoterQ73694178
Signaling to p53: breaking the MDM2-p53 circuitQ77430977
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53Q24290402
PUMA induces the rapid apoptosis of colorectal cancer cellsQ24291462
PUMA, a novel proapoptotic gene, is induced by p53Q24291463
A model for p53-induced apoptosisQ24313374
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repressionQ24533291
p53, the cellular gatekeeper for growth and divisionQ27860990
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosisQ28144256
Definition of a consensus binding site for p53Q28207794
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor geneQ28250929
14-3-3sigma is a p53-regulated inhibitor of G2/M progressionQ28276061
The complexity of p53 modulation: emerging patterns from divergent signalsQ28284854
Tumor suppressor p53 is a direct transcriptional activator of the human bax geneQ28306186
Bax suppresses tumorigenesis and stimulates apoptosis in vivoQ28506493
Bax-deficient mice with lymphoid hyperplasia and male germ cell deathQ28589360
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasiaQ29615437
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6Q29622924
Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesisQ33886271
Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivoQ33886276
Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosisQ33916603
Sequence-specific transcriptional activation is essential for growth suppression by p53.Q35086763
p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damageQ35123816
p53 and E2F-1 cooperate to mediate apoptosisQ35185411
Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53Q35205701
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosisQ35885582
p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugsQ36401199
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expressionQ36551292
Cytokines inhibit p53-mediated apoptosis but not p53-mediated G1 arrestQ36555730
Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietinQ36675415
Identification and classification of p53-regulated genesQ36747355
Identification of a Novel p53 Functional Domain That Is Necessary for Mediating ApoptosisQ38337319
Wild-type p53 negatively regulates the expression of a microtubule-associated proteinQ41148864
Essential role for p53-mediated transcription in E1A-induced apoptosisQ41302308
Growth factor modulation of p53-mediated growth arrest versus apoptosisQ41365779
Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.Q41414258
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectregulation of gene expressionQ411391
apoptotic processQ14599311
P304page(s)1049-1051
P577publication date2001-11-01
P1433published inCell Death & DifferentiationQ2943974
P1476titlep53-dependent pathways of apoptosis
P478volume8

Reverse relations

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