| P50 | author | Pier Paolo Pandolfi | Q7191735 |
| | John M Asara | Q56936246 |
| | Chih-Hung Hsu | Q64683308 |
| | Wenjian Gan | Q89518739 |
| | Fabin Dang | Q125195038 |
| | Archita Venugopal Menon | Q125195186 |
| P2093 | author name string | Yang Shi | |
| | Wenyi Wei | |
| | Jinfang Zhang | |
| | Nicholas R Leslie | |
| | Priyanka Tibarewal | |
| | Yu-Ru Lee | |
| | Jesse M Katon | |
| P2860 | cites work | Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function | Q24295164 |
| | A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination | Q24299264 |
| | MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 |
| | Methylation of the retinoblastoma tumor suppressor by SMYD2 | Q24300912 |
| | ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 |
| | Regulation of p53 activity through lysine methylation | Q24311514 |
| | Repression of p53 activity by Smyd2-mediated methylation | Q24315991 |
| | P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 |
| | A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication | Q24626425 |
| | Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair | Q24669691 |
| | Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 |
| | Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor | Q27676347 |
| | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain | Q27676675 |
| | Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor | Q27684769 |
| | PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 |
| | 53BP1 regulates DSB repair using Rif1 to control 5' end resection | Q28000120 |
| | A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice | Q28000121 |
| | PTEN is a protein tyrosine phosphatase for IRS1 | Q28239790 |
| | A secreted PTEN phosphatase that enters cells to alter signaling and survival | Q28292188 |
| | Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response | Q28297156 |
| | MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites | Q28304648 |
| | Essential role for nuclear PTEN in maintaining chromosomal integrity | Q28513781 |
| | RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. | Q29465543 |
| | MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents. | Q51358936 |
| | High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 |
| | The functions and regulation of the PTEN tumour suppressor: new modes and prospects | Q88955683 |
| | Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair | Q92085285 |
| | Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway | Q92090098 |
| | PTEN arginine methylation by PRMT6 suppresses PI3K-AKT signaling and modulates pre-mRNA splicing | Q92459709 |
| | Identification of LEM-14 inhibitor of the oncoprotein NSD2 | Q93342438 |
| | The functions and regulation of the PTEN tumour suppressor | Q29615536 |
| | p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks | Q30014828 |
| | DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. | Q34017960 |
| | PTEN interacts with histone H1 and controls chromatin condensation | Q34364654 |
| | Double-strand break repair: 53BP1 comes into focus | Q34391068 |
| | 3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation | Q34401976 |
| | p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice | Q34784963 |
| | PTEN positively regulates UVB-induced DNA damage repair | Q35141546 |
| | Wolf-Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damage | Q35164644 |
| | NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming | Q35569571 |
| | A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors | Q35640249 |
| | Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA. | Q35642171 |
| | Inhibition of Nuclear Receptor Binding SET Domain 2/Multiple Myeloma SET Domain by LEM-06 Implication for Epigenetic Cancer Therapies | Q35820972 |
| | Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors | Q36042091 |
| | PTEN, more than the AKT pathway | Q36753139 |
| | WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition | Q37163743 |
| | PTEN in cancer, metabolism, and aging. | Q37331397 |
| | Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress | Q37380066 |
| | DNA damage response: three levels of DNA repair regulation | Q38118223 |
| | PTEN. | Q38218236 |
| | Non-histone protein methylation as a regulator of cellular signalling and function | Q38285792 |
| | The NSD family of protein methyltransferases in human cancer | Q38459795 |
| | Histone Modifications and Cancer | Q38796064 |
| | Nonhistone Lysine Methylation in the Regulation of Cancer Pathways | Q38801008 |
| | Targeting the cancer epigenome for therapy | Q38821103 |
| | PTEN regulates DNA replication progression and stalled fork recovery. | Q38855105 |
| | Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure | Q38878518 |
| | The Role of Nuclear Receptor-Binding SET Domain Family Histone Lysine Methyltransferases in Cancer | Q39134084 |
| | Regulation of the tumor suppressor PTEN by SUMO. | Q39271041 |
| | SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane | Q39328325 |
| | PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity | Q39388363 |
| | PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors | Q39644716 |
| | MMSET is the key molecular target in t(4;14) myeloma | Q42142425 |
| | Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination. | Q48268350 |
| | The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells | Q48362692 |
| P433 | issue | 9 | |
| P304 | page(s) | 1306-1323 | |
| P577 | publication date | 2019-06-19 | |
| P1433 | published in | Cancer Discovery | Q15724440 |
| P1476 | title | PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage | |
| P478 | volume | 9 | |