| scholarly article | Q13442814 |
| P50 | author | Stephanie Könen-Waisman | Q63241950 |
| P2093 | author name string | Jonathan C Howard | |
| John C Boothroyd | |||
| Jon P Boyle | |||
| Julia P Hunn | |||
| Jörn Coers | |||
| Aliaksandr Khaminets | |||
| Daniela Preukschat | |||
| Gabriela Reichmann | |||
| Yang O Zhao | |||
| Yi-Ching Ong | |||
| P2860 | cites work | The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage | Q21184175 |
| Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death | Q21559499 | ||
| Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells | Q21562583 | ||
| Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis | Q22065557 | ||
| Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39. | Q22065998 | ||
| Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases. | Q22255523 | ||
| The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series | Q24654258 | ||
| The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy | Q27933717 | ||
| IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3 | Q28255726 | ||
| Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis | Q28505187 | ||
| Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii | Q28506496 | ||
| Two families of GTPases dominate the complex cellular response to IFN-gamma | Q28507786 | ||
| Specific antiviral activity demonstrated by TGTP, a member of a new family of interferon-induced GTPases | Q28585808 | ||
| Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection | Q28586576 | ||
| Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo | Q28587410 | ||
| The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection | Q28589928 | ||
| Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages | Q29547420 | ||
| The role of autophagy during the early neonatal starvation period | Q29547489 | ||
| Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function | Q29617462 | ||
| The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes | Q30484263 | ||
| Regulation of macrophage motility by Irgm1 | Q30492916 | ||
| The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling | Q33259406 | ||
| ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii | Q33274196 | ||
| Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth | Q33369511 | ||
| Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages | Q33766719 | ||
| On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other | Q55953061 | ||
| A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei | Q58858878 | ||
| Synchronous invasion of host cells by Toxoplasma gondii | Q63409172 | ||
| Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts | Q73478363 | ||
| Quantitative immunolocalization of a P29 protein (GRA7), a new antigen of toxoplasma gondii | Q77552490 | ||
| Isolation of toxoplasma from cerebrospinal fluid of a living infant in Holland | Q79573252 | ||
| Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane | Q80032319 | ||
| p47 GTPases regulate Toxoplasma gondii survival in activated macrophages | Q33788028 | ||
| Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP. | Q34008942 | ||
| The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis | Q34119804 | ||
| Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47 | Q34272123 | ||
| Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia. | Q34287918 | ||
| A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii | Q34591236 | ||
| High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein | Q34725225 | ||
| Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10. | Q34771892 | ||
| Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii | Q34772368 | ||
| The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice | Q35080460 | ||
| p47 GTPases: regulators of immunity to intracellular pathogens | Q35709631 | ||
| Immune control of phagosomal bacteria by p47 GTPases | Q36032380 | ||
| Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages | Q36228861 | ||
| The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation | Q36515566 | ||
| The interferon-inducible GTPases. | Q36528795 | ||
| A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence. | Q36710769 | ||
| IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens | Q36759545 | ||
| The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding | Q36853414 | ||
| Identification of a virulence-associated antigen of Toxoplasma gondii by use of a mouse monoclonal antibody | Q36990210 | ||
| Cell-autonomous immunity to Toxoplasma gondii in mouse and man. | Q37006950 | ||
| Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families. | Q37034561 | ||
| Inhibition of growth of Toxoplasma gondii in cultured fibroblasts by human recombinant gamma interferon. | Q37081863 | ||
| Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue | Q37087502 | ||
| Polymorphic secreted kinases are key virulence factors in toxoplasmosis | Q37105671 | ||
| Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells | Q37106751 | ||
| The IRG proteins: a function in search of a mechanism | Q37136172 | ||
| Balance of Irgm protein activities determines IFN-gamma-induced host defense | Q37159144 | ||
| Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens | Q37193067 | ||
| Kinetic modeling of Toxoplasma gondii invasion | Q37217149 | ||
| Functional aspects of Toll-like receptor/MyD88 signalling during protozoan infection: focus on Toxoplasma gondii | Q37374974 | ||
| Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review | Q37476750 | ||
| Brain-tissue cysts in rats infected with the RH strain of Toxoplasma gondii | Q44845501 | ||
| GRA7, an excretory 29 kDa Toxoplasma gondii dense granule antigen released by infected host cells | Q48038533 | ||
| Toxoplasma gondii virulence markers identified by random amplified polymorphic DNA polymerase chain reaction | Q48055644 | ||
| Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47). | Q50067094 | ||
| Toxoplasma gondii: Genetic crosses reveal phenotypic suppression of hydroxyurea resistance by fluorodeoxyuridine resistance | Q52707248 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | vacuole | Q127702 |
| Toxoplasma gondii | Q131003 | ||
| P304 | page(s) | 939-61 | |
| P577 | publication date | 2010-07-01 | |
| P1433 | published in | Cellular Microbiology | Q1921948 |
| P1476 | title | Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole | |
| P478 | volume | 12 |
| Q36143601 | A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells |
| Q28481222 | A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins |
| Q47095280 | A mechanistic study of Toxoplasma gondii ROP18 inhibiting differentiation of C17.2 neural stem cells |
| Q35102296 | ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18. |
| Q52425356 | Analysis of the virulence determination mechanisms in a local Toxoplasma strain (T.gHB1) isolated from central China. |
| Q58097217 | Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii |
| Q35269455 | Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells |
| Q34673845 | Autophagy in immunity and cell-autonomous defense against intracellular microbes |
| Q24595707 | Autophagy in immunity and inflammation |
| Q35143581 | Border maneuvers: deployment of mucosal immune defenses against Toxoplasma gondii |
| Q35018100 | CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection |
| Q38034630 | Comparative genomic analysis of eutherian interferon-γ-inducible GTPases |
| Q21090491 | Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy |
| Q36298354 | Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens. |
| Q27321401 | Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it |
| Q37459452 | Development of 116 kDa Fraction for Detecting Experimental Toxoplasma gondii Infections in Mice |
| Q45028437 | Eimeria falciformis infection of the mouse caecum identifies opposing roles of IFNγ-regulated host pathways for the parasite development |
| Q40070106 | Evaluation of immune responses induced by rhoptry protein 5 and rhoptry protein 7 DNA vaccines against Toxoplasma gondii |
| Q46703685 | Exposing Toxoplasma gondii hiding inside the vacuole: a role for GBPs, autophagy and host cell death. |
| Q39244181 | From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home. |
| Q33602978 | GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response |
| Q37682433 | Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems |
| Q38918759 | Genomics of apicomplexan parasites. |
| Q40358072 | Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii |
| Q34697891 | Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii |
| Q34592579 | Hammondia hammondi harbors functional orthologs of the host-modulating effectors GRA15 and ROP16 but is distinguished from Toxoplasma gondii by a unique transcriptional profile |
| Q34339536 | Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes |
| Q34697840 | Have it your way: how polymorphic, injected kinases and pseudokinases enable Toxoplasma to subvert host defenses |
| Q41684078 | Host-Toxoplasma gondii Coadaptation Leads to Fine Tuning of the Immune Response |
| Q48231826 | Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. |
| Q36374867 | IFN-inducible GTPases in host cell defense |
| Q34778494 | IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins |
| Q40520196 | IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes. |
| Q35187600 | IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria |
| Q38437242 | Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18. |
| Q27323191 | Identification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance system |
| Q24612341 | Immune response and immunopathology during toxoplasmosis |
| Q38263938 | Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy |
| Q59033885 | In astrocytes the accumulation of the immunity-related GTPases Irga6 and Irgb6 at the vacuole of Toxoplasma gondii is dependent on the parasite virulence |
| Q40482585 | Induction of specific humoral immune response in mice immunized with ROP18 nanospheres from Toxoplasma gondii. |
| Q58735600 | Inhibition of Nitric Oxide Production in Activated Macrophages Caused by Infection Occurs by Distinct Mechanisms in Different Mouse Macrophage Cell Lines |
| Q92093394 | Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense |
| Q46023230 | Innate Immunity to Intracellular Pathogens: Balancing Microbial Elimination and Inflammation. |
| Q38181331 | Innate immunity to Toxoplasma gondii infection |
| Q91890897 | Innate, adaptive, and cell-autonomous immunity against Toxoplasma gondii infection |
| Q39435797 | Interaction of the innate immune system with positive-strand RNA virus replication organelles |
| Q38834935 | Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease. |
| Q38634433 | Interferon-inducible GTPases in cell autonomous and innate immunity |
| Q34114819 | Interferon-inducible effector mechanisms in cell-autonomous immunity |
| Q37835983 | Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation. |
| Q34425347 | Interferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases |
| Q64074180 | Interplay Between , Autophagy, and Autophagy Proteins |
| Q36971309 | Invasion and intracellular survival by protozoan parasites |
| Q90630662 | In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration |
| Q39127726 | Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells |
| Q35995190 | Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection. |
| Q41924884 | Mechanisms and functions of guanylate-binding proteins and related interferon-inducible GTPases: roles in intracellular lysis of pathogens |
| Q34033981 | Modulation of innate immunity by Toxoplasma gondii virulence effectors |
| Q64089468 | Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice |
| Q37764125 | Monocytes mediate mucosal immunity to Toxoplasma gondii |
| Q34470850 | Parasites paralyze cellular host defense system to promote virulence |
| Q34257517 | Partial protective effect of intranasal immunization with recombinant Toxoplasma gondii rhoptry protein 17 against toxoplasmosis in mice |
| Q59357405 | Partners in anti-crime: how interferon-inducible GTPases and autophagy proteins team up in cell-intrinsic host defense |
| Q24617053 | Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence |
| Q28476607 | Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii |
| Q39591613 | Quo vadis? Interferon-inducible GTPases go to their target membranes via the LC3-conjugation system of autophagy. |
| Q33753887 | ROP18 is a key factor responsible for virulence difference between Toxoplasma gondii and Neospora caninum |
| Q37262073 | Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse |
| Q40067644 | Resistance towards monensin is proposed to be acquired in a Toxoplasma gondii model by reduced invasion and egress activities, in addition to increased intracellular replication |
| Q90290829 | Rhoptry and Dense Granule Secreted Effectors Regulate CD8+ T Cell Recognition of Toxoplasma gondii Infected Host Cells |
| Q37119146 | Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity |
| Q34056304 | Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts |
| Q34314006 | Subversion of host cellular functions by the apicomplexan parasites |
| Q92718987 | TLR11-independent inflammasome activation is critical for CD4+ T cell-derived IFN-γ production and host resistance to Toxoplasma gondii |
| Q28476673 | The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels |
| Q31148891 | The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance |
| Q33940781 | The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens |
| Q57075090 | The Interplay of Host Autophagy and Eukaryotic Pathogens |
| Q37334013 | The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7. |
| Q33861156 | The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice |
| Q24617222 | The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii |
| Q36931641 | The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii |
| Q26863747 | The gut mucosal immune response to Toxoplasma gondii |
| Q35943304 | The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion |
| Q36222916 | The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens |
| Q27341809 | The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18 |
| Q34325516 | The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response. |
| Q57065812 | The role of host autophagy machinery in controlling Toxoplasma infection |
| Q36041799 | The secreted kinase ROP18 defends Toxoplasma's border |
| Q45104207 | The virulence-related rhoptry protein 5 (ROP5) of Toxoplasma Gondii is a novel vaccine candidate against toxoplasmosis in mice |
| Q38731005 | Toxoplasma Effectors Targeting Host Signaling and Transcription |
| Q36191387 | Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling |
| Q42836798 | Toxoplasma gondii peroxiredoxin promotes altered macrophage function, caspase-1-dependent IL-1β secretion enhances parasite replication |
| Q35172341 | Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination. |
| Q56768394 | Toxoplasmosis |
| Q36179296 | Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins |
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