EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

scientific article

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates is …
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scholarly articleQ13442814

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P356DOI10.1101/GR.073585.107
P3181OpenCitations bibliographic resource ID343290
P932PMC publication ID2652215
P698PubMed publication ID19029536
P5875ResearchGate publication ID23493435

P50authorRichard M. DurbinQ4583003
Ewan BirneyQ4869199
Abel Ureta-VidalQ28322649
Albert J. VilellaQ30503083
P2093author name stringJessica Severin
Li Heng
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
MUSCLE: a multiple sequence alignment method with reduced time and space complexityQ21284290
The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate OriginsQ22065826
Evolutionary and Biomedical Insights from the Rhesus Macaque GenomeQ22065872
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequencesQ22122236
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolutionQ22122484
Genome sequence of the Brown Norway rat yields insights into mammalian evolutionQ22122498
Initial sequencing and comparative analysis of the mouse genomeQ22122521
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammalsQ24630840
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The Bioperl toolkit: Perl modules for the life sciencesQ24682183
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The genome sequence of Drosophila melanogasterQ27860796
PAML 4: phylogenetic analysis by maximum likelihoodQ27860834
OrthoMCL: Identification of Ortholog Groups for Eukaryotic GenomesQ27860860
A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum LikelihoodQ27861000
An efficient algorithm for large-scale detection of protein familiesQ28131838
Database resources of the National Center for Biotechnology InformationQ29614503
Automatic clustering of orthologs and in-paralogs from pairwise species comparisonsQ29615401
A phylogenomic gene cluster resource: the Phylogenetically Inferred Groups (PhIGs) databaseQ33239650
Phylogenetic reconstruction of orthology, paralogy, and conserved synteny for dog and humanQ33258810
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genomeQ35840707
Tree pattern matching in phylogenetic trees: automatic search for orthologs or paralogs in homologous gene sequence databasesQ48150517
MSOAR: a high-throughput ortholog assignment system based on genome rearrangement.Q50869057
Ancestral reconstruction of segmental duplications reveals punctuated cores of human genome evolution.Q51904419
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectphylogeneticsQ171184
P304page(s)327-35
P577publication date2009-02-01
P1433published inGenome ResearchQ5533485
P1476titleEnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates
P478volume19

Reverse relations

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Q34158485Heterosis in early maize ear inflorescence development: a genome-wide transcription analysis for two maize inbred lines and their hybrid
Q34173095High-quality sequence clustering guided by network topology and multiple alignment likelihood
Q95818134High-throughput capturing and characterization of mutations in essential genes of Caenorhabditis elegans
Q33853987High-throughput comparison, functional annotation, and metabolic modeling of plant genomes using the PlantSEED resource
Q50080966Highly Expressed Genes Are Preferentially Co-Opted for C4 Photosynthesis.
Q39596997Highly conserved elements discovered in vertebrates are present in non-syntenic loci of tunicates, act as enhancers and can be transcribed during development
Q42007006Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans
Q40797079Histochemical analysis of testis specific gene 13 in human normal and malignant tissues
Q42870574Historical constraints on vertebrate genome evolution.
Q51551021Historical profiling of maize duplicate genes sheds light on the evolution of C4 photosynthesis in grasses.
Q34426574Hominoid-specific de novo protein-coding genes originating from long non-coding RNAs
Q26750493Homoeologs: What Are They and How Do We Infer Them?
Q47376400HuPho: the human phosphatase portal
Q35216525Human dominant disease genes are enriched in paralogs originating from whole genome duplication
Q46062139Human testis-specific genes are under relaxed negative selection
Q33864635Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
Q36054040Identification and characterization of lineage-specific highly conserved noncoding sequences in Mammalian genomes
Q40880372Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen.
Q37742959Identification of MicroRNA Targets of Capsicum spp. Using MiRTrans-a Trans-Omics Approach
Q35693465Identification of Ohnolog Genes Originating from Whole Genome Duplication in Early Vertebrates, Based on Synteny Comparison across Multiple Genomes
Q37363175Identification of deleterious mutations within three human genomes
Q33829884Identification of introns harboring functional sequence elements through positional conservation.
Q31061948Identification of novel human damage response proteins targeted through yeast orthology.
Q35616862Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses
Q24609000Identification of transcriptional regulators in the mouse immune system
Q35774036Improved Detection and Characterization of Copy Number Variations Among Diverse Pig Breeds by Array CGH.
Q35161245Improved evidence-based genome-scale metabolic models for maize leaf, embryo, and endosperm
Q35367107Improved gene tree error correction in the presence of horizontal gene transfer
Q53589942Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology
Q36663988Improving genome-wide scans of positive selection by using protein isoforms of similar length
Q34768428Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel.
Q34761563Improving the measurement of semantic similarity between gene ontology terms and gene products: insights from an edge- and IC-based hybrid method
Q38619658In silico prediction and characterization of secondary metabolite biosynthetic gene clusters in the wheat pathogen Zymoseptoria tritici
Q44723240In-depth proteomic analysis of whole testis tissue from the adult rhesus macaque
Q38714433Incorporating tree-thinking and evolutionary time scale into developmental biology
Q30979181Increasing alternative promoter repertories is positively associated with differential expression and disease susceptibility
Q92724692Independent Transposon Exaptation Is a Widespread Mechanism of Redundant Enhancer Evolution in the Mammalian Genome
Q26766407Inferring Orthologs: Open Questions and Perspectives
Q34569170Inferring evolution of gene duplicates using probabilistic models and nonparametric belief propagation
Q34558713Inferring hierarchical orthologous groups from orthologous gene pairs
Q36434699Information Commons for Rice (IC4R).
Q28708852Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence
Q28611130Insights into the evolution of longevity from the bowhead whale genome
Q34465001Insights into the evolutionary features of human neurodegenerative diseases
Q89983086Integrated structural and evolutionary analysis reveals common mechanisms underlying adaptive evolution in mammals
Q118108068Integrating gene annotation with orthology inference at scale
Q34518118Integration of Orthogonal Signaling by the Notch and Dpp Pathways in Drosophila
Q36337749Intergenic Alu exonisation facilitates the evolution of tissue-specific transcript ends.
Q34173743Interrogation of alternative splicing events in duplicated genes during evolution
Q38850632Introgression and repeated co-option facilitated the recurrent emergence of C4 photosynthesis among close relatives
Q36434704JuncDB: an exon-exon junction database
Q34552862Kerfuffle: a web tool for multi-species gene colocalization analysis
Q35968822Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription Factors
Q116816621Kingella pumchi sp. nov., an organism isolated from human vertebral puncture tissue
Q35753710Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes
Q42640079Large scale comparison of global gene expression patterns in human and mouse.
Q58482881Large-Scale Parsimony Analysis of Metazoan Indels in Protein-Coding Genes
Q37544701Large-scale inference of gene function through phylogenetic annotation of Gene Ontology terms: case study of the apoptosis and autophagy cellular processes
Q37392827Late-replicating CNVs as a source of new genes
Q42696657Learning causal networks with latent variables from multivariate information in genomic data
Q38696679Lineage-specific duplications of Muroidea Faim and Spag6 genes and atypical accelerated evolution of the parental Spag6 gene
Q64293430Linking genetic, metabolic, and phenotypic diversity among Saccharomyces cerevisiae strains using multi-omics associations
Q37689133Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish.
Q90596686Liriodendron genome sheds light on angiosperm phylogeny and species-pair differentiation
Q42143357Long-term asymmetrical acceleration of protein evolution after gene duplication
Q58064247Loose ends: almost one in five human genes still have unresolved coding status
Q94464424Loss of Arabidopsis β-COP Function Affects Golgi Structure, Plant Growth and Tolerance to Salt Stress
Q28295827Low-pass DNA sequencing of 1200 Sardinians reconstructs European Y-chromosome phylogeny
Q33522314MSOAR 2.0: Incorporating tandem duplications into ortholog assignment based on genome rearrangement
Q64106608Magic roundabout is an endothelial-specific ohnolog of ROBO1 which neo-functionalized to an essential new role in angiogenesis
Q30041295Malaria parasites possess a telomere repeat-binding protein that shares ancestry with transcription factor IIIA
Q92231216Mammalian Annotation Database for improved annotation and functional classification of Omics datasets from less well-annotated organisms
Q27015020Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction
Q34276930Mechanisms and evolutionary patterns of mammalian and avian dosage compensation
Q42146149Membrane environment imposes unique selection pressures on transmembrane domains of G protein-coupled receptors
Q34558058Mendelian and non-Mendelian regulation of gene expression in maize
Q41916305MetaPhOrs: orthology and paralogy predictions from multiple phylogenetic evidence using a consistency-based confidence score.
Q45943697Metabolic Pathway Assignment of Plant Genes based on Phylogenetic Profiling-A Feasibility Study.
Q27316581Metabolic and chaperone gene loss marks the origin of animals: evidence for Hsp104 and Hsp78 chaperones sharing mitochondrial enzymes as clients
Q43810520Metabolic flux is a determinant of the evolutionary rates of enzyme-encoding genes
Q33764893MiR-277/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni
Q37270728Mitochondrial-nuclear interactions: compensatory evolution or variable functional constraint among vertebrate oxidative phosphorylation genes?
Q47138466MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins.
Q91942370Molecular Characteristics of Brucella Isolates Collected From Humans in Hainan Province, China
Q40422255Molecular Evolution of the Neural Crest Regulatory Network in Ray-Finned Fish.
Q36422268Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn.
Q44976469Molecular evolution and network-level analysis of the N-glycosylation metabolic pathway across primates
Q58695874Molecular parallelism in fast-twitch muscle proteins in echolocating mammals
Q50026963Monitoring the 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) modification in eukaryotic tRNAs via the gamma-toxin endonuclease.
Q37614948Most parsimonious reconciliation in the presence of gene duplication, loss, and deep coalescence using labeled coalescent trees
Q34502040Mouse genome database 2016.
Q21092720Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis
Q33945362MultiMSOAR 2.0: an accurate tool to identify ortholog groups among multiple genomes
Q59798420Multilevel comparative bioinformatics to investigate evolutionary relationships and specificities in gene annotations: an example for tomato and grapevine
Q28242198Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes
Q35057778NECTAR: a database of codon-centric missense variant annotations
Q37466814NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo.
Q43218001Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals.
Q33881339Natural selection drives the accumulation of amino acid tandem repeats in human proteins.
Q35753618Network Modules of the Cross-Species Genotype-Phenotype Map Reflect the Clinical Severity of Human Diseases
Q29396093Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders
Q24656606Nme protein family evolutionary history, a vertebrate perspective
Q35622998No excess gene movement is detected off the avian or lepidopteran Z chromosome
Q33670801Non-homologous sex chromosomes of birds and snakes share repetitive sequences
Q36122410Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity
Q37563897Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks
Q28484069Nrac, a novel nutritionally-regulated adipose and cardiac-enriched gene
Q90711716OHNOLOGS v2: a comprehensive resource for the genes retained from whole genome duplication in vertebrates
Q24610080OMA 2011: orthology inference among 1000 complete genomes
Q92999345OMA standalone: orthology inference among public and custom genomes and transcriptomes
Q90281202ORTHOSCOPE: An Automatic Web Tool for Phylogenetically Inferring Bilaterian Orthogroups with User-Selected Taxa
Q37490530On the origin and evolutionary history of NANOG.
Q28678692On the origins of Mendelian disease genes in man: the impact of gene duplication
Q35845649Optimizing and benchmarking de novo transcriptome sequencing: from library preparation to assembly evaluation.
Q34039734Ortho2ExpressMatrix--a web server that interprets cross-species gene expression data by gene family information
Q24595539OrthoDB: a hierarchical catalog of animal, fungal and bacterial orthologs
Q24608310OrthoDB: the hierarchical catalog of eukaryotic orthologs in 2011
Q64122763OrthoList 2: A New Comparative Genomic Analysis of Human and Genes
Q35007364OrthoList: a compendium of C. elegans genes with human orthologs
Q35226472Ortholog identification in the presence of domain architecture rearrangement
Q46310708Orthologous Matrix (OMA) algorithm 2.0: more robust to asymmetric evolutionary rates and more scalable hierarchical orthologous group inference
Q36102213Orthologs, turn-over, and remolding of tRNAs in primates and fruit flies
Q24635071Orthology prediction methods: a quality assessment using curated protein families
Q38599475Orthonome - a new pipeline for predicting high quality orthologue gene sets applicable to complete and draft genomes
Q36380916PICARA, an analytical pipeline providing probabilistic inference about a priori candidates genes underlying genome-wide association QTL in plants
Q38432649PLAZA: a comparative genomics resource to study gene and genome evolution in plants
Q35067830POGs2: a web portal to facilitate cross-species inferences about protein architecture and function in plants
Q28543185PON-P2: prediction method for fast and reliable identification of harmful variants
Q38123537PTP1B: a simple enzyme for a complex world
Q38137634PainNetworks: a web-based resource for the visualisation of pain-related genes in the context of their network associations
Q35054959Parallel evolution of chordate cis-regulatory code for development
Q91713316Patterns of gene evolution following duplications and speciations in vertebrates
Q28657708Patterns of positive selection in seven ant genomes
Q34341628Pervasive gene content variation and copy number variation in maize and its undomesticated progenitor
Q34135908PhylDiag: identifying complex synteny blocks that include tandem duplications using phylogenetic gene trees.
Q41877586PhyleasProg: a user-oriented web server for wide evolutionary analyses.
Q39015302PhyloPro2.0: a database for the dynamic exploration of phylogenetically conserved proteins and their domain architectures across the Eukarya
Q28074488Phylogenetic Profiling for Probing the Modular Architecture of the Human Genome
Q92645733Phylogenetic Reclassification of Vertebrate Melatonin Receptors To Include Mel1d
Q56993997Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome
Q34329311Phylogenetic patterns of emergence of new genes support a model of frequent de novo evolution
Q34211397Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Q21245376Phylogenomic analyses support the position of turtles as the sister group of birds and crocodiles (Archosauria)
Q38978558Phylogenomic analysis of gene co-expression networks reveals the evolution of functional modules.
Q24612855PhylomeDB v3.0: an expanding repository of genome-wide collections of trees, alignments and phylogeny-based orthology and paralogy predictions
Q34387795PhylomeDB v4: zooming into the plurality of evolutionary histories of a genome
Q28683167Phylotastic! Making tree-of-life knowledge accessible, reusable and convenient
Q34498367PhytoPath: an integrative resource for plant pathogen genomics.
Q37557019Plant Reactome: a resource for plant pathways and comparative analysis
Q42848317Polytomy refinement for the correction of dubious duplications in gene trees
Q34402745Positive selection during the evolution of the blood coagulation factors in the context of their disease-causing mutations
Q42063703Predicting physical interactions between protein complexes
Q34441875Predicting the functional effect of amino acid substitutions and indels
Q111629806Preferential retention of the slowly evolving gene in pairs of duplicates in angiosperm genomes
Q38711027Preliminary characterization of putative structural cuticular proteins in the malaria vector Anopheles sinensis.
Q37428410Presence-absence variation in A. thaliana is primarily associated with genomic signatures consistent with relaxed selective constraints
Q89579237Primary orthologs from local sequence context
Q50422131Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes.
Q27026709Programmed necrosis in the cross talk of cell death and inflammation
Q36386280Properties of genes essential for mouse development
Q41847165Protein connectivity and protein complexity promotes human gene duplicability in a mutually exclusive manner
Q47250514Protein disorder in the centrosome correlates with complexity in cell types number
Q34421535Protein flexibility facilitates quaternary structure assembly and evolution
Q35611201Protein homology reveals new targets for bioactive small molecules
Q37430050Protein subcellular relocalization increases the retention of eukaryotic duplicate genes
Q46610724Proteins with Highly Evolvable Domain Architectures Are Nonessential but Highly Retained
Q90406514Putative contributions of the sex chromosome proteins SOX3 and SRY to neurodevelopmental disorders
Q34302143Quality of computationally inferred gene ontology annotations
Q35205182Quickly finding orthologs as reciprocal best hits with BLAT, LAST, and UBLAST: how much do we miss?
Q28661205Rapid diversification of FoxP2 in teleosts through gene duplication in the teleost-specific whole genome duplication event
Q36355017Rapid genome reshaping by multiple-gene loss after whole-genome duplication in teleost fish suggested by mathematical modeling
Q58702562Rat BodyMap transcriptomes reveal unique circular RNA features across tissue types and developmental stages
Q28608563Reactome pathway analysis to enrich biological discovery in proteomics data sets
Q28298042Reactome: a database of reactions, pathways and biological processes
Q47440542Reading m6A in the Transcriptome: m6A-Binding Proteins
Q42560814Reconciliation of gene and species trees
Q37216482Reconciliation revisited: handling multiple optima when reconciling with duplication, transfer, and loss
Q35801624Reconstructing a SuperGeneTree minimizing reconciliation
Q46255304Reconstructing protein and gene phylogenies using reconciliation and soft-clustering
Q33994309Reconstructing the architecture of the ancestral amniote genome
Q33766662Refining orthologue groups at the transcript level
Q57462774Regulation of Root Angle and Gravitropism
Q34382690Relaxed purifying selection and possibly high rate of adaptation in primate lineage-specific genes
Q33773781Representing kidney development using the gene ontology
Q89495217Resequencing 200 Flax Cultivated Accessions Identifies Candidate Genes Related to Seed Size and Weight and Reveals Signatures of Artificial Selection
Q35930303Revealing mammalian evolutionary relationships by comparative analysis of gene clusters
Q55290600Role of duplicate genes in determining the tissue-selectivity of hereditary diseases.
Q35541953Role of testis-specific gene expression in sex-chromosome evolution of Anopheles gambiae.
Q35560551STBase: one million species trees for comparative biology
Q42034775Screening for candidate genes involved in the production of mouse subventricular zone proliferative cells and an estimation of their changes in evolutionary pressure during primate evolution
Q28818367Screening lifespan-extending drugs in Caenorhabditis elegans via label propagation on drug-protein networks
Q28748496Segmental duplications in the human genome reveal details of pseudogene formation
Q47190138Selective Constraints on Coding Sequences of Nervous System Genes Are a Major Determinant of Duplicate Gene Retention in Vertebrates
Q51010606Selectivity determinants of GPCR-G-protein binding.
Q37661803Selectome update: quality control and computational improvements to a database of positive selection
Q55017090Sensing the cilium, digital capture of ciliary data for comparative genomics investigations.
Q35211667Sequence, structural and expression divergence of duplicate genes in the bovine genome
Q39658690Sequencing and analysis of an Irish human genome
Q22122079Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Q36758500Seventy-five genetic loci influencing the human red blood cell
Q28706282Sharing and re-use of phylogenetic trees (and associated data) to facilitate synthesis
Q92015555SimSpliceEvol: alternative splicing-aware simulation of biological sequence evolution
Q33633483Similarly strong purifying selection acts on human disease genes of all evolutionary ages
Q42317732Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types
Q43258229Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor
Q42610265Small homologous blocks in phytophthora genomes do not point to an ancient whole-genome duplication.
Q89697176Spatiotemporal Differentiation of Alpine Butterfly Parnassius glacialis (Papilionidae: Parnassiinae) in China: Evidence from Mitochondrial DNA and Nuclear Single Nucleotide Polymorphisms
Q39002203Spatiotemporal variation of mammalian protein complex stoichiometries.
Q35079606Specific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing
Q41869319Speeding up all-against-all protein comparisons while maintaining sensitivity by considering subsequence-level homology
Q28645675Spider Transcriptomes Identify Ancient Large-Scale Gene Duplication Event Potentially Important in Silk Gland Evolution
Q44872565Spotted Gar and the Evolution of Innate Immune Receptors.
Q37473190Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont
Q30002371Standardized benchmarking in the quest for orthologs
Q33613732State aggregation for fast likelihood computations in molecular evolution
Q35906459Structural and functional annotation of the MADS-box transcription factor family in grapevine
Q34724017Structural and functional annotation of the porcine immunome
Q28742243Structural and functional relationships between photoreceptor tetraspanins and other superfamily members
Q34472565Structural divergence in vertebrate phylogeny of a duplicated prototype galectin
Q24308820Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1
Q36273166Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.
Q42724602SwissTargetPrediction: a web server for target prediction of bioactive small molecules
Q89982979Sympatric speciation of wild emmer wheat driven by ecology and chromosomal rearrangements
Q38823713SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets
Q28751512Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes
Q21145302Systematically differentiating functions for alternatively spliced isoforms through integrating RNA-seq data
Q49178768Systems Analysis of the Liver Transcriptome in Adult Male Zebrafish Exposed to the Plasticizer (2-Ethylhexyl) Phthalate (DEHP).
Q92590360TaWAK6 encoding wall-associated kinase is involved in wheat resistance to leaf rust similar to adult plant resistance
Q33575868TargetOrtho: a phylogenetic footprinting tool to identify transcription factor targets
Q21145323Testing the ortholog conjecture with comparative functional genomic data from mammals
Q38631170The Adaptive Evolution Database (TAED): A New Release of a Database of Phylogenetically Indexed Gene Families from Chordates.
Q22066274The Burmese python genome reveals the molecular basis for extreme adaptation in snakes
Q35100720The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma
Q35253738The GOA database: gene Ontology annotation updates for 2015
Q35720244The Identification of Circulating MiRNA in Bovine Serum and Their Potential as Novel Biomarkers of Early Mycobacterium avium subsp paratuberculosis Infection
Q46268168The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces.
Q37608193The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
Q42710675The Role of Retrotransposons in Gene Family Expansions in the Human and Mouse Genomes
Q24299186The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly
Q37257672The Tetraodon nigroviridis reference transcriptome: developmental transition, length retention and microsynteny of long non-coding RNAs in a compact vertebrate genome
Q28596345The Transcriptomic Evolution of Mammalian Pregnancy: Gene Expression Innovations in Endometrial Stromal Fibroblasts
Q35630729The UniProt-GO Annotation database in 2011.
Q28260701The clustering of functionally related genes contributes to CNV-mediated disease
Q104486466The de novo genome assembly of Tapiscia sinensis and the transcriptomic and developmental bases of androdioecy
Q42681725The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAs
Q28600967The drug target genes show higher evolutionary conservation than non-target genes
Q22122074The duck genome and transcriptome provide insight into an avian influenza virus reservoir species
Q31108150The duplicated genes database: identification and functional annotation of co-localised duplicated genes across genomes
Q28248746The early expansion and evolutionary dynamics of POU class genes
Q50445428The evolution and function of protein tandem repeats in plants.
Q43134967The evolution and functional diversification of the deubiquitinating enzyme superfamily
Q38661582The evolution of duplicate gene expression in mammalian organs
Q29617170The evolution of gene expression levels in mammalian organs
Q50738717The evolution of lineage-specific clusters of single nucleotide substitutions in the human genome.
Q34400081The evolution of lncRNA repertoires and expression patterns in tetrapods
Q35826230The evolutionary fate of alternatively spliced homologous exons after gene duplication
Q35095539The evolutionary panorama of organ-specifically expressed or repressed orthologous genes in nine vertebrate species
Q35112922The functional consequences of variation in transcription factor binding.
Q37643713The genome of Onchocerca volvulus, agent of river blindness
Q64109196The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination system
Q21146634The genome of the sparganosis tapeworm Spirometra erinaceieuropaei isolated from the biopsy of a migrating brain lesion
Q64070855The genomes of pecan and Chinese hickory provide insights into Carya evolution and nut nutrition
Q35909943The genomic basis of parasitism in the Strongyloides clade of nematodes
Q34986211The grapevine gene nomenclature system
Q34342479The hourglass and the early conservation models--co-existing patterns of developmental constraints in vertebrates
Q21129222The iPlant Collaborative: Cyberinfrastructure for Plant Biology
Q34102856The impact of focused Gene Ontology curation of specific mammalian systems
Q30431966The impact of gene expression regulation on evolution of extracellular signaling pathways
Q34431226The inference of gene trees with species trees
Q37237987The integrated landscape of driver genomic alterations in glioblastoma
Q47550309The invasive MED/Q Bemisia tabaci genome: a tale of gene loss and gene gain.
Q40253098The link between orthology relations and gene trees: a correction perspective
Q37076988The mRNA-bound proteome of the early fly embryo
Q40808577The mammalian complement system as an epitome of host-pathogen genetic conflicts.
Q33517995The other side of comparative genomics: genes with no orthologs between the cow and other mammalian species
Q36611523The paralog-to-contig assignment problem: high quality gene models from fragmented assemblies
Q36640777The plant ontology as a tool for comparative plant anatomy and genomic analyses
Q34084950The reduced kinome of Ostreococcus tauri: core eukaryotic signalling components in a tractable model species
Q34983597The relationship between gene isoform multiplicity, number of exons and protein divergence
Q28601481The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
Q100558717The structural variation landscape in 492 Atlantic salmon genomes
Q90448937The sugarcane mitochondrial genome: assembly, phylogenetics and transcriptomics
Q34622011The transcript catalogue of the short-lived fish Nothobranchius furzeri provides insights into age-dependent changes of mRNA levels
Q50422616The unique features of proteins depicting the chicken amniotic fluid.
Q35030401The vertebrate ancestral repertoire of visual opsins, transducin alpha subunits and oxytocin/vasopressin receptors was established by duplication of their shared genomic region in the two rounds of early vertebrate genome duplications
Q41757244The vertebrate muscle-specific RING finger protein family includes MuRF4--a novel, conserved E3-ubiquitin ligase.
Q22065285The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage.
Q64259127The widespread increase in inter-individual variability of gene expression in the human brain with age
Q29616593The zebrafish reference genome sequence and its relationship to the human genome
Q58695408Time-Series Analysis of Tumorigenesis in a Murine Skin Carcinogenesis Model
Q30431285Time-dependent gene expression analysis of the developing superior olivary complex
Q36234551Tissue-Specificity of Gene Expression Diverges Slowly between Orthologs, and Rapidly between Paralogs.
Q33575525Touring Ensembl: a practical guide to genome browsing
Q38446542Towards Consensus Gene Ages
Q33748950Transcriptional response to hepatitis C virus infection and interferon-alpha treatment in the human liver
Q37218555Transcriptome analyses of the Dof-like gene family in grapevine reveal its involvement in berry, flower and seed development
Q36317537Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes
Q92515510Transcriptome-Wide Patterns of the Genetic and Expression Variations in Two Sympatric Schizothoracine Fishes in a Tibetan Plateau Glacier Lake
Q33528261Translog, a web browser for studying the expression divergence of homologous genes
Q37739557Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew.
Q28660718TreeFam v9: a new website, more species and orthology-on-the-fly
Q36479265TreeFix: statistically informed gene tree error correction using species trees
Q34994742Triticeae resources in Ensembl Plants
Q27334789USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level
Q33879784Ultra-fast sequence clustering from similarity networks with SiLiX.
Q35207816Uncovering adaptive evolution in the human lineage.
Q43136115Understanding Brassicaceae evolution through ancestral genome reconstruction.
Q29615864UniProt Knowledgebase: a hub of integrated protein data
Q42560541Unified modeling of gene duplication, loss, and coalescence using a locus tree
Q36899633Universal allosteric mechanism for Gα activation by GPCRs
Q57589985Using WormBase: A Genome Biology Resource for Caenorhabditis elegans and Related Nematodes
Q34794421Using an isolated rat kidney model to identify kidney origin proteins in urine
Q34237570VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
Q50104544ViCTree: An automated framework for taxonomic classification from protein sequences.
Q31030149Wasabi: An Integrated Platform for Evolutionary Sequence Analysis and Data Visualization.
Q34426308What evidence is there for the homology of protein-protein interactions?
Q31106392Whole transcriptome data analysis of zebrafish mutants affecting muscle development
Q58086412Whole-Genome Alignment and Comparative Annotation
Q36475646Whole-genome duplication and the functional diversification of teleost fish hemoglobins
Q35632409Whole-genome duplications spurred the functional diversification of the globin gene superfamily in vertebrates.
Q96135941Whole-genome resequencing of wild and domestic sheep identifies genes associated with morphological and agronomic traits
Q28269956WormBase 2016: expanding to enable helminth genomic research
Q46985455WormBase 2017: molting into a new stage.
Q38375438WormBase ParaSite - a comprehensive resource for helminth genomics
Q36895137WormBase: Annotating many nematode genomes
Q42513763Zygotic Genome Activation Occurs Shortly after Fertilization in Maize
Q33575547eHive: an artificial intelligence workflow system for genomic analysis
Q24644077eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations
Q24619608eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges
Q30488940expVIP: a Customizable RNA-seq Data Analysis and Visualization Platform.
Q40200884iRegulon and i-cisTarget: Reconstructing Regulatory Networks Using Motif and Track Enrichment
Q35212382iRegulon: from a gene list to a gene regulatory network using large motif and track collections
Q34062687morFeus: a web-based program to detect remotely conserved orthologs using symmetrical best hits and orthology network scoring
Q36688906ncRNA orthologies in the vertebrate lineage
Q35856899orthoFind Facilitates the Discovery of Homologous and Orthologous Proteins

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