scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1053442094 |
P356 | DOI | 10.1038/SJ.ONC.1205213 |
P698 | PubMed publication ID | 11857088 |
P5875 | ResearchGate publication ID | 11504927 |
P50 | author | Garth L. Nicolson | Q17489765 |
P2093 | author name string | Jörg Haier | |
P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region | Q22010498 | ||
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2 | Q22253866 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility | Q24554511 | ||
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway | Q28139300 | ||
Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases | Q28255035 | ||
Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin | Q28264272 | ||
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity | Q28300726 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems | Q28586004 | ||
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells | Q33586807 | ||
PTEN: a tumour suppressor that functions as a phospholipid phosphatase | Q33594251 | ||
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway | Q33599964 | ||
PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis | Q33723736 | ||
PTEN gene and integrin signaling in cancer | Q33765703 | ||
The multiple roles of PTEN in tumor suppression | Q33849727 | ||
The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase | Q33888694 | ||
Protein tyrosine phosphatases in signal transduction. | Q34419522 | ||
Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis | Q35250337 | ||
Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton | Q36220765 | ||
Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways | Q36256326 | ||
Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B. | Q36288200 | ||
Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. | Q36301565 | ||
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: role of integrin expression and cytoskeletal components | Q38273491 | ||
Protein tyrosine phosphatases in cell transformation | Q40813403 | ||
Integrin transmembrane signaling and cytoskeletal control | Q40952551 | ||
Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion | Q41018719 | ||
Signaling through focal adhesion kinase | Q41359146 | ||
Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow | Q41751721 | ||
Influence of phosphotyrosine kinase inhibitors on adhesive properties of highly and poorly metastatic HT-29 colon carcinoma cells to collagen | Q45298448 | ||
Beta1-integrin-mediated dynamic adhesion of colon carcinoma cells to extracellular matrix under laminar flow | Q45299813 | ||
Tumor cell adhesion of human colon carcinoma cells with different metastatic properties to extracellular matrix under dynamic conditions of laminar flow | Q45302100 | ||
PTEN/MMAC1/TEP1 involvement in primary prostate cancers. | Q47814101 | ||
Deletion 10q23.2-q23.33 in a patient with gastrointestinal juvenile polyposis and other features of a Cowden-like syndrome. | Q51996177 | ||
PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis. | Q55476772 | ||
Tyrosine phosphorylation of pp125FAK and paxillin in aortic endothelial cells induced by mechanical strain | Q71435733 | ||
Differential regulation of protein-tyrosine phosphatases by integrin alpha IIb beta 3 through cytoskeletal reorganization and tyrosine phosphorylation in human platelets | Q71692364 | ||
Mutation analysis of the PTEN/MMAC1 gene in cancers of the digestive tract | Q73008420 | ||
Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype | Q73316223 | ||
Endothelial gene regulation by laminar shear stress | Q73788938 | ||
PTEN germ-line mutations in juvenile polyposis coli | Q74026971 | ||
Mutational abrogation of the PTEN/MMAC1 gene in gastrointestinal polyps in patients with Cowden disease | Q77494213 | ||
PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation | Q78026206 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell adhesion | Q187640 |
fluid flow | Q12142910 | ||
colon carcinoma | Q18554829 | ||
P304 | page(s) | 1450-60 | |
P577 | publication date | 2002-02-21 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow | |
P478 | volume | 21 |
Q30442233 | A novel model to identify interaction partners of the PTEN tumor suppressor gene in human bladder cancer |
Q34717955 | Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis |
Q35943250 | Clinical implications of PTEN and VEGF expression status, as well as microvessel density in esophageal squamous cell carcinoma |
Q40241749 | Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2. |
Q54976490 | Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development. |
Q36956729 | Focal adhesion kinase: a promising target for anticancer therapy |
Q26797287 | Focus on PTEN Regulation |
Q81471088 | Genetic and pathologic changes associated with lymphovascular invasion of colorectal adenocarcinoma |
Q33569192 | In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell--endothelial cell interaction |
Q45178212 | Integrins can directly mediate metastatic tumor cell adhesion within the liver sinusoids |
Q52559414 | Integrity of actin fibers and microtubules influences metastatic tumor cell adhesion. |
Q24797910 | Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor |
Q39868557 | Metastatic tumor cell arrest in the liver-lumen occlusion and specific adhesion are not exclusive |
Q35256204 | NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN. |
Q54295478 | Non-digestible fraction of beans (Phaseolus vulgaris L.) modulates signalling pathway genes at an early stage of colon cancer in Sprague-Dawley rats. |
Q30478479 | Organ-specific metastatic tumor cell adhesion and extravasation of colon carcinoma cells with different metastatic potential |
Q37290801 | PCR-SSCP-DNA sequencing method in detecting PTEN gene mutation and its significance in human gastric cancer |
Q38198345 | PTEN function: the long and the short of it. |
Q35721747 | Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-κB Pathway |
Q59304352 | Resveratrol inhibits Erk1/2-mediated adhesion of cancer cells via activating PP2A-PTEN signaling network |
Q38723005 | Role of key genetic mutations on increasing migration of brain cancer cells through confinement. |
Q33784365 | The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression |
Search more.