| scholarly article | Q13442814 |
| P50 | author | Robert Lefkowitz | Q80910 |
| William E Miller | Q55187035 | ||
| Marc Caron | Q64858849 | ||
| Larry S Barak | Q114424966 | ||
| Seungkirl Ahn | Q117251943 | ||
| P2093 | author name string | Wei Chen | |
| Roel Nusse | |||
| Derk ten Berge | |||
| Jeff Brown | |||
| Liaoyuan A Hu | |||
| P2860 | cites work | G protein-coupled receptor kinases | Q77366588 |
| Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes | Q22008730 | ||
| beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins | Q24292014 | ||
| Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference | Q24294614 | ||
| Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3 | Q28138462 | ||
| The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits | Q28142257 | ||
| PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling | Q28204348 | ||
| A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation | Q28252768 | ||
| Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway | Q28586005 | ||
| Mechanisms of Wnt signaling in development | Q29547537 | ||
| Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor | Q29618735 | ||
| Seven-transmembrane receptors | Q29619896 | ||
| Casein kinase 2associates with and phosphorylates Dishevelled | Q33886745 | ||
| Arresting developments in heptahelical receptor signaling and regulation | Q34540902 | ||
| Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins | Q34568617 | ||
| Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis. | Q34666439 | ||
| The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling | Q35124049 | ||
| Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization | Q40920202 | ||
| Regulated endocytic routing modulates wingless signaling in Drosophila embryos. | Q41919592 | ||
| Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins | Q43687982 | ||
| Casein kinase I transduces Wnt signals | Q47069139 | ||
| P433 | issue | 5638 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endocytosis | Q189814 |
| P304 | page(s) | 1391-4 | |
| P577 | publication date | 2003-09-05 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4 | |
| P478 | volume | 301 |
| Q36752946 | A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins |
| Q33585370 | A Wnt-planar polarity pathway instructs neurite branching by restricting F-actin assembly through endosomal signaling. |
| Q24318611 | A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5) |
| Q33249099 | A critical role for endocytosis in Wnt signaling |
| Q30544835 | A disorder-to-order structural transition in the COOH-tail of Fz4 determines misfolding of the L501fsX533-Fz4 mutant |
| Q48447275 | A novel Wnt5a-Frizzled4 signaling pathway mediates activity-independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4. |
| Q28115305 | ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma |
| Q50299929 | ARRB bind GPCRs |
| Q34577233 | ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors |
| Q35647525 | Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds |
| Q33859624 | Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis |
| Q38729054 | Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin. |
| Q28594193 | All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases |
| Q40094304 | Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor |
| Q35051128 | Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations |
| Q90573431 | Arf6 regulates RhoB subcellular localization to control cancer cell invasion |
| Q35565885 | Arrestin development: emerging roles for beta-arrestins in developmental signaling pathways |
| Q87537652 | Arrestin2 modulates androgen receptor activation |
| Q28582124 | Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4 |
| Q38114209 | Arrestins come of age: a personal historical perspective |
| Q21184142 | Arrestins: ubiquitous regulators of cellular signaling pathways |
| Q33700017 | Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling |
| Q24299892 | Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling |
| Q35765873 | Asymmetric localizations of LIN-17/Fz and MIG-5/Dsh are involved in the asymmetric B cell division in C. elegans |
| Q48365002 | Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression. |
| Q38028853 | Balanced ubiquitination determines cellular responsiveness to extracellular stimuli |
| Q24314681 | Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt |
| Q51124579 | Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis |
| Q37166800 | Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice. |
| Q35800324 | Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. |
| Q33890802 | Beyond desensitization: physiological relevance of arrestin-dependent signaling. |
| Q24323341 | CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia |
| Q35818355 | Cargo- and compartment-selective endocytic scaffold proteins |
| Q24299047 | Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin |
| Q36028155 | Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling |
| Q50298830 | DVL2 is phosphorylated by PKC |
| Q24302441 | Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation |
| Q47072609 | Delivery of wingless to the ventral mesoderm by the developing central nervous system ensures proper patterning of individual slouch-positive muscle progenitors |
| Q35817048 | Desensitization of G protein-coupled receptors and neuronal functions |
| Q33589705 | Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach |
| Q54978768 | Developmental vascular regression is regulated by a Wnt/β-catenin, MYC, P21 (CDKN1A) pathway that controls cell proliferation and cell death. |
| Q41330963 | Differential stability of flamingo protein complexes underlies the establishment of planar polarity |
| Q24298046 | Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling |
| Q30491381 | Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells |
| Q57476125 | Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization |
| Q28594365 | Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling |
| Q52348724 | Dishevelled: A masterful conductor of complex Wnt signals. |
| Q36431494 | Dishevelled: a mobile scaffold catalyzing development |
| Q34074005 | Distinct roles of arrestin 1 protein in photoreceptors during Drosophila development |
| Q33603037 | Dkk1 stabilizes Wnt co-receptor LRP6: implication for Wnt ligand-induced LRP6 down-regulation |
| Q26766251 | Endocytic control of signaling at the plasma membrane |
| Q37541507 | Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis |
| Q36956908 | Endocytosis: a positive or a negative influence on Wnt signalling? |
| Q35779157 | Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling |
| Q42791086 | Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements |
| Q54503120 | Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling. |
| Q28242018 | Frizzled-7 turnover at the plasma membrane is regulated by cell density and the Ca(2+) -dependent protease calpain-1 |
| Q39193257 | G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms |
| Q37454339 | G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. |
| Q37209133 | G protein-independent cell-based assays for drug discovery on seven-transmembrane receptors |
| Q33712410 | GSK3: a multifaceted kinase in Wnt signaling |
| Q38671626 | Genetic deficiency of Wnt5a diminishes disease severity in a murine model of rheumatoid arthritis. |
| Q34586848 | Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism |
| Q39669210 | Genome-wide association study among four horse breeds identifies a common haplotype associated with in vitro CD3+ T cell susceptibility/resistance to equine arteritis virus infection |
| Q35034870 | Heterotrimeric G-protein, Gα16, is a critical downstream effector of non-canonical Wnt signaling and a potent inhibitor of transformed cell growth in non small cell lung cancer |
| Q30542083 | Human embryonic stem cell-derived cardiomyocytes migrate in response to gradients of fibronectin and Wnt5a |
| Q57074174 | Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth |
| Q90519433 | Identification of novel triazole inhibitors of Wnt/β-catenin signaling based on the Niclosamide chemotype |
| Q30586942 | In vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryos |
| Q50802085 | Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice |
| Q37332427 | Inhibition of WNT signaling by G protein-coupled receptor (GPCR) kinase 2 (GRK2). |
| Q33281815 | Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation. |
| Q30504867 | Initiation of synapse formation by Wnt-induced MuSK endocytosis |
| Q37809668 | International Union of Basic and Clinical Pharmacology. LXXX. The Class Frizzled Receptors |
| Q33719095 | Intracellular trafficking and signaling in development |
| Q26822956 | Keeping Wnt signalosome in check by vesicular traffic |
| Q47354687 | Kinase cogs go forward and reverse in the Wnt signaling machine |
| Q90045088 | Membrane capacitance recordings resolve dynamics and complexity of receptor-mediated endocytosis in Wnt signalling |
| Q58605183 | MicroRNA-29a-3p enhances dental implant osseointegration of hyperlipidemic rats via suppressing dishevelled 2 and frizzled 4 |
| Q36599592 | Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. |
| Q64113057 | Molecular evolutionary and structural analysis of familial exudative vitreoretinopathy associated FZD4 gene |
| Q37460101 | Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention. |
| Q35213474 | Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling |
| Q37812683 | New avenues to target Wnt/β-catenin signaling |
| Q36678037 | New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors |
| Q39678821 | Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4 |
| Q47203960 | Non-canonical Wnt signaling regulates neural stem cell quiescence during homeostasis and after demyelination |
| Q33882256 | Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function |
| Q50538442 | PLD1 regulates Xenopus convergent extension movements by mediating Frizzled7 endocytosis for Wnt/PCP signal activation |
| Q38804461 | PTH and Vitamin D. |
| Q24303654 | Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch |
| Q46973015 | Phosphorylation of frizzled-3. |
| Q35870841 | Phylogenetic and Evolutionary Analyses of the Frizzled Gene Family in Common Carp (Cyprinus carpio) Provide Insights into Gene Expansion from Whole-Genome Duplications |
| Q42214750 | Planar cell polarity controls directional Notch signaling in the Drosophila leg. |
| Q39092602 | Planar cell polarity in moving cells: think globally, act locally |
| Q42091527 | Planar cell polarity pathway regulates nephrin endocytosis in developing podocytes |
| Q28749129 | Planar cell polarity signaling: from fly development to human disease |
| Q28274945 | Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling |
| Q37907064 | Potential cross-talk between (pro)renin receptors and Wnt/frizzled receptors in cardiovascular and renal disorders |
| Q28510950 | Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context |
| Q24313293 | Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10 |
| Q40601346 | Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2. |
| Q45345847 | Regulation of Notch signalling by non-visual beta-arrestin |
| Q28266829 | Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors |
| Q38064702 | Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential. |
| Q37676928 | Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking |
| Q51822098 | Ror2 expression in squamous cell carcinoma and epithelial dysplasia of the oral cavity. |
| Q38360630 | Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements |
| Q24318774 | Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins |
| Q30834526 | Signaling of human frizzled receptors to the mating pathway in yeast |
| Q57359903 | Signaling on the endocytic pathway |
| Q34604768 | Small molecule modulators of Wnt/β-catenin signaling. |
| Q36565309 | Sorting nexin 27 interacts with Fzd7 and mediates Wnt signalling |
| Q37834841 | Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia |
| Q27665037 | Structural Analysis of the Interaction between Dishevelled2 and Clathrin AP-2 Adaptor, A Critical Step in Noncanonical Wnt Signaling |
| Q36454906 | Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure |
| Q92040403 | Structure-function analysis of β-arrestin Kurtz reveals a critical role of receptor interactions in downregulation of GPCR signaling in vivo |
| Q35933368 | Subcellular translocation of the eGFP-tagged TRPL channel in Drosophila photoreceptors requires activation of the phototransduction cascade |
| Q35148896 | Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth |
| Q36153315 | Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis |
| Q55280530 | The Coordinated Activities of nAChR and Wnt Signaling Regulate Intestinal Stem Cell Function in Mice. |
| Q39381430 | The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling |
| Q21092882 | The Frizzled family: receptors for multiple signal transduction pathways |
| Q27316057 | The Integrated Role of Wnt/β-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamics |
| Q36797326 | The Intracellular Loop 2 F328S Frizzled-4 Mutation Implicated in Familial Exudative Vitreoretinopathy Impairs Dishevelled Recruitment |
| Q36058465 | The Myopic-Ubpy-Hrs nexus enables endosomal recycling of Frizzled |
| Q24315249 | The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation |
| Q36339909 | The Wingless homolog Wnt5a stimulates phagocytosis but not bacterial killing |
| Q39042481 | The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells |
| Q33505762 | The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling. |
| Q26783047 | The emerging roles of β-arrestins in fibrotic diseases |
| Q48341993 | The function of endocytosis in Wnt signaling |
| Q33607743 | The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin |
| Q40435195 | The mechanism of endogenous receptor activation functionally distinguishes prototype canonical and noncanonical Wnts |
| Q90027731 | The polarity protein VANG-1 antagonizes Wnt signaling by facilitating Frizzled endocytosis |
| Q42825361 | The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon |
| Q26852972 | The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction |
| Q37960345 | The role of endocytosis in activating and regulating signal transduction |
| Q28304550 | The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration |
| Q37651978 | The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis |
| Q37997883 | The tangled web of non-canonical Wnt signalling in neural migration |
| Q39077281 | The thyroid hormone nuclear receptors and the Wnt/β-catenin pathway: An intriguing liaison. |
| Q50636049 | The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling |
| Q24293671 | The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling |
| Q37798661 | The various roles of ubiquitin in Wnt pathway regulation. |
| Q28116790 | Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons |
| Q28246395 | Transduction of receptor signals by beta-arrestins |
| Q36663074 | Type 1 angiotensin receptor pharmacology: signaling beyond G proteins. |
| Q34629577 | Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities |
| Q28116308 | VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin |
| Q47299786 | WNT Signaling in Cardiac and Vascular Disease. |
| Q92424065 | WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer |
| Q26777942 | WNT-5A: signaling and functions in health and disease |
| Q37635264 | WNT/Frizzled signalling: receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3 |
| Q51674853 | WNT5A and Its Receptors in the Bone-Cancer Dialogue. |
| Q50298828 | WNT5A binds FZD4 |
| Q24316338 | WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis |
| Q50298829 | WNT5A-FZD4 recruits DVL2 |
| Q45318264 | WNT5A-dependent internalization of FZD4 |
| Q50298832 | WNT5A:FZD4 is endocytosed |
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| Q34768164 | Wnt signaling and stem cell control |
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| Q41412781 | Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. |
| Q47619354 | Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development. |
| Q24597197 | Wnt/beta-catenin signaling and small molecule inhibitors |
| Q36955697 | Wnt/beta-catenin signaling controls development of the blood-brain barrier |
| Q37109729 | Wnt/beta-catenin signaling: new (and old) players and new insights |
| Q90675233 | Wnt/β-Catenin Signaling and Obesity |
| Q26823272 | Wnt/β-catenin signaling and disease |
| Q33366930 | Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation |
| Q39335491 | Wnt5a Increases the Glycolytic Rate and the Activity of the Pentose Phosphate Pathway in Cortical Neurons. |
| Q38501378 | Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors |
| Q42609832 | Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization |
| Q28588878 | Wnt5a regulates distinct signalling pathways by binding to Frizzled2 |
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| Q37145391 | Xenopus Wntless and the retromer complex cooperate to regulate XWnt4 secretion |
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| Q33730604 | beta-Arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways? |
| Q35804809 | beta-arrestins: traffic cops of cell signaling |
| Q27011654 | microRNA regulation of Wnt signaling pathways in development and disease |
| Q50298831 | p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis |
| Q34138284 | ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease |
| Q35647627 | β-Arrestin and dishevelled coordinate biased signaling |
| Q27325551 | β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation |
| Q35175384 | β-Arrestin-mediated receptor trafficking and signal transduction |
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| Q41863336 | β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein. |
| Q44686499 | β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling. |
| Q33814944 | β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain |
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