HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response

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HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...624660M
P356DOI10.1371/JOURNAL.PONE.0024660
P3181OpenCitations bibliographic resource ID1422135
P932PMC publication ID3176279
P698PubMed publication ID21949742
P5875ResearchGate publication ID51665667

P50authorYaakov NahmiasQ16215021
Oren ShiboletQ125205189
P2093author name stringRamnik J Xavier
Boaz Tirosh
Emmanuelle Merquiol
Tobias Mueller
Daniel Goldenberg
Dotan Uzi
P2860cites workViewing a stressful episode of ER: is ATF6 the triage nurse?Q83323502
Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-kappaB activationQ39821567
Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2.Q39964572
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Plasma cell-specific transcription factor XBP-1s binds to and transactivates the Epstein-Barr virus BZLF1 promoterQ40075775
Cell culture and infection system for hepatitis C virusQ40150021
Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletionQ40421534
Hepatitis C virus, ER stress, and oxidative stressQ40432170
IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3.Q40674809
Human Cytomegalovirus Induces the Endoplasmic Reticulum Chaperone BiP through Increased Transcription and Activation of Translation by Using the BiP Internal Ribosome Entry SiteQ41894476
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance developmentQ42168234
Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic miceQ42628139
Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.Q42982187
Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1.Q42994110
Hepatitis C virus nonstructural proteins are localized in a modified endoplasmic reticulum of cells expressing viral subgenomic repliconsQ43036635
Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A.Q43037981
Hepatitis C virus envelope proteins regulate CHOP via induction of the unfolded protein responseQ43524712
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C.Q44332232
Inhibition of the interferon-inducible protein kinase PKR by HCV E2 proteinQ22010192
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A proteinQ24319002
Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathwayQ24537844
Robust hepatitis C virus infection in vitroQ27470013
Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein responseQ27487012
HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA MiceQ27487963
Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic MiceQ27490446
Global epidemiology of hepatitis C virus infectionQ27860799
Production of infectious hepatitis C virus in tissue culture from a cloned viral genomeQ27860899
Complete replication of hepatitis C virus in cell cultureQ27860934
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIFQ29547901
Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signalingQ29614206
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunitiesQ29617768
Evasion of intracellular host defence by hepatitis C virusQ29618976
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteinsQ33262919
Interaction of hepatitis C virus proteins with host cell membranes and lipidsQ34160337
Intramembrane proteolysis and endoplasmic reticulum retention of hepatitis C virus core proteinQ34193354
Production of infectious human cytomegalovirus virions is inhibited by drugs that disrupt calcium homeostasis in the endoplasmic reticulumQ34228644
eIF2 and the control of cell physiologyQ34554304
Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replicationQ34797179
Orchestrating the unfolded protein response in health and diseaseQ35001604
Role of the unfolded protein response in cell deathQ36351719
Unconventional splicing of XBP-1 mRNA in the unfolded protein responseQ36989874
PERK and PKR: old kinases learn new tricksQ37140418
From endoplasmic-reticulum stress to the inflammatory responseQ37225354
Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegansQ37385784
New and experimental therapies for HCV.Q37539700
Effects of hepatitis C virus envelope glycoprotein unfolded protein response activation on translation and transcription.Q39797992
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
P304page(s)e24660
P577publication date2011-09-19
P1433published inPLOS OneQ564954
P1476titleHCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response
P478volume6

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