scholarly article | Q13442814 |
P2093 | author name string | Miklós Sahin-Tóth | |
Richárd Szmola | |||
P2860 | cites work | Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen | Q46911281 |
Functional analysis of pancreatitis-associated missense mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene. | Q51796788 | ||
Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis. | Q53276855 | ||
Reduced pancreatic volume and beta-cell area in patients with chronic pancreatitis. | Q53383717 | ||
That which does not kill me makes me stronger: adapting to chronic ER stress | Q81405125 | ||
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene | Q24311652 | ||
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis | Q24645261 | ||
Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism | Q24650338 | ||
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis | Q24658116 | ||
Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y | Q24675338 | ||
Biochemical models of hereditary pancreatitis | Q24675973 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis | Q28138406 | ||
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis | Q28145585 | ||
Clinical and genetic characteristics of hereditary pancreatitis in Europe | Q28250117 | ||
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis | Q30815377 | ||
Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis | Q33328503 | ||
Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis | Q34732835 | ||
Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells | Q36212907 | ||
Endoplasmic reticulum stress signaling in disease | Q36610455 | ||
Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. | Q36805212 | ||
Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis. | Q37181595 | ||
From endoplasmic-reticulum stress to the inflammatory response | Q37225354 | ||
Signal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitis | Q37395316 | ||
Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells | Q40223778 | ||
Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation | Q41110653 | ||
Heavy chain binding protein (BiP/GRP78) and endoplasmin are exported from the endoplasmic reticulum in rat exocrine pancreatic cells, similar to protein disulfide-isomerase | Q41617941 | ||
Cell death in pancreatitis: caspases protect from necrotizing pancreatitis | Q46091205 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 365-372 | |
P577 | publication date | 2009-11-30 | |
P1433 | published in | Gut | Q5621669 |
P1476 | title | Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells | |
P478 | volume | 59 |
Q42725781 | A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis |
Q31814814 | A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding. |
Q38963298 | Asparagine-linked glycosylation of human chymotrypsin C is required for folding and secretion but not for enzyme activity |
Q37725572 | Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiency |
Q39571536 | Bromelain inhibits nuclear factor kappa-B translocation, driving human epidermoid carcinoma A431 and melanoma A375 cells through G(2)/M arrest to apoptosis |
Q37591305 | Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice |
Q27693296 | Chymotrypsin C mutations in chronic pancreatitis |
Q40906883 | Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk |
Q39334642 | Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants |
Q43633901 | Effect of emodin on endoplasmic reticulum stress in rats with severe acute pancreatitis |
Q38802376 | Endoplasmic reticulum stress is activated in acute pancreatitis |
Q34283421 | Endoplasmic reticulum stress is chronically activated in chronic pancreatitis |
Q36927073 | Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis. |
Q33843764 | Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway |
Q34667122 | Genetic and phenotypic heterogeneity in tropical calcific pancreatitis |
Q37842752 | Genetic basis of chronic pancreatitis in Asia Pacific region |
Q39398523 | Genetic risk in chronic pancreatitis: the misfolding-dependent pathway |
Q34358474 | Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis |
Q38822781 | Karyopherin Alpha 2 Promotes the Inflammatory Response in Rat Pancreatic Acinar Cells Via Facilitating NF-κB Activation. |
Q36793423 | Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice |
Q97548636 | Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice |
Q35837145 | Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis. |
Q37918238 | Molecular mechanisms of pancreatic injury |
Q39305127 | Pancreatic Disorders |
Q36775826 | Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitis |
Q38034035 | Pathogenic mechanisms of acute pancreatitis |
Q38840155 | Pathophysiological mechanisms in acute pancreatitis: Current understanding |
Q37802876 | Proteomic analysis of zymogen granules. |
Q36122718 | SEC23B is required for the maintenance of murine professional secretory tissues |
Q38776190 | TRAM1 protects AR42J cells from caerulein-induced acute pancreatitis through ER stress-apoptosis pathway |
Q36174524 | Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis |
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