| scholarly article | Q13442814 |
| P50 | author | Jan David Alexander Groneberg | Q1174606 |
| Matthias Blüher | Q15431947 | ||
| Michael Stumvoll | Q30434795 | ||
| Milan Macek | Q89467851 | ||
| Joost P H Drenth | Q90032062 | ||
| Heiko Witt | Q90796906 | ||
| Jonas Rosendahl | Q90986615 | ||
| Eesh Bhatia | Q91105235 | ||
| Béla Ózsvári | Q114257179 | ||
| Rene H M Te Morsche | Q114332638 | ||
| Volker Keim | Q114332640 | ||
| Richárd Szmola | Q114332894 | ||
| Roland Pfützer | Q114332895 | ||
| Gourdas Choudhuri | Q114332896 | ||
| Ulrike Witt | Q114332897 | ||
| Johann Ockenga | Q114332898 | ||
| Andreas Kage | Q114332899 | ||
| Renate Nickel | Q114332900 | ||
| Gero Puhl | Q123912984 | ||
| Miklós Sahin-Tóth | Q38318675 | ||
| Bertram Wiedenmann | Q41604544 | ||
| Thomas Berg | Q42981905 | ||
| Johannes-Matthias Löhr | Q49338331 | ||
| Thomas Gress | Q59785425 | ||
| Niels Teich | Q87987079 | ||
| Peter Kovacs | Q88964174 | ||
| P2093 | author name string | Carsten Büning | |
| Olfert Landt | |||
| Hans-Ulrich Schulz | |||
| Joachim Mössner | |||
| Péter Hegyi | |||
| Hartmut Schmidt | |||
| Hans Bödeker | |||
| Kaspar Truninger | |||
| P2860 | cites work | Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene | Q24311652 |
| Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis | Q24658116 | ||
| Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y | Q24675338 | ||
| Biochemical models of hereditary pancreatitis | Q24675973 | ||
| A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis | Q28138105 | ||
| SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis | Q28138406 | ||
| Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis | Q28145585 | ||
| Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis | Q28250483 | ||
| A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis | Q30815377 | ||
| Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations | Q34152791 | ||
| Mutations of the cationic trypsinogen in hereditary pancreatitis | Q34472573 | ||
| SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh | Q39437851 | ||
| Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation | Q41110653 | ||
| Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis | Q43074804 | ||
| Mutation in the SPINK1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis | Q43626455 | ||
| Functional analysis of pancreatitis-associated missense mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene. | Q51796788 | ||
| Hereditary pancreatitis caused by triplication of the trypsinogen locus | Q79314164 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | chronic pancreatitis | Q1996053 |
| P304 | page(s) | 78-82 | |
| P577 | publication date | 2008-01-01 | |
| P1433 | published in | Nature Genetics | Q976454 |
| P1476 | title | Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis | |
| P478 | volume | 40 |
| Q34140192 | A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis |
| Q34784372 | A comprehensive study indicates PRSS1 gene is significantly associated with pancreatitis |
| Q30000783 | A conservative assessment of the major genetic causes of idiopathic chronic pancreatitis: data from a comprehensive analysis of PRSS1, SPINK1, CTRC and CFTR genes in 253 young French patients |
| Q37660241 | A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis |
| Q34594385 | Alcohol and Smoking as Risk Factors in an Epidemiology Study of Patients With Chronic Pancreatitis |
| Q34985636 | Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis. |
| Q27014123 | Alcoholic pancreatitis: A tale of spirits and bacteria |
| Q39260953 | An Evaluation of Factors Associated With Pathogenic PRSS1, SPINK1, CTFR, and/or CTRC Genetic Variants in Patients With Idiopathic Pancreatitis |
| Q38182330 | An update on pancreatic pathophysiology (do we have to rewrite pancreatic pathophysiology?). |
| Q38036389 | Asparaginase-associated pancreatitis in children |
| Q38963298 | Asparagine-linked glycosylation of human chymotrypsin C is required for folding and secretion but not for enzyme activity |
| Q35304061 | Assessing the pathological relevance of SPINK1 promoter variants |
| Q37725572 | Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiency |
| Q34732835 | Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis |
| Q60609750 | Autoimmune Pankreatitis |
| Q36251687 | CTRC gene polymorphism (p.G60=; c.180 C > T) in acute pancreatitis |
| Q26775406 | Caldecrin: A pancreas-derived hypocalcemic factor, regulates osteoclast formation and function |
| Q37640180 | Can a polymorphism in the thalassemia gene and a heterozygote CFTR mutation cause acute pancreatitis? |
| Q45991735 | Cathepsin B-mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice. |
| Q38805333 | Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group. |
| Q86874923 | Characterization of two deletions of the CTRC locus |
| Q30234471 | Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment |
| Q52519464 | Chronic pancreatitis. |
| Q52984504 | Chronic pancreatitis. |
| Q35212921 | Chymotrypsin C (caldecrin) is associated with enamel development |
| Q34503091 | Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2. |
| Q27693296 | Chymotrypsin C mutations in chronic pancreatitis |
| Q50921436 | Clinical and morphological characteristics of sporadic genetically determined pancreatitis as compared to idiopathic pancreatitis: higher risk of pancreatic cancer in CFTR variants. |
| Q37586742 | Clinical aspects of pancreatogenic diabetes secondary to hereditary pancreatitis. |
| Q35907078 | Common Variants in CLDN2 and MORC4 Genes Confer Disease Susceptibility in Patients with Chronic Pancreatitis |
| Q33970803 | Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis |
| Q38760758 | Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2. |
| Q40906883 | Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk |
| Q37172601 | Comprehensive screening for PRSS1, SPINK1, CFTR, CTRC and CLDN2 gene mutations in Chinese paediatric patients with idiopathic chronic pancreatitis: a cohort study |
| Q39334642 | Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants |
| Q33511586 | Connections between genetics and clinical data: Role of MCP-1, CFTR, and SPINK-1 in the setting of acute, acute recurrent, and chronic pancreatitis |
| Q43246426 | Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen. |
| Q51632031 | Discovery and Functional Annotation of PRSS1 Promoter Variants in Chronic Pancreatitis. |
| Q53172779 | Do genetic variants in the SPINK1 gene affect the level of serum PSTI? |
| Q30482616 | ENDEAVOUR update: a web resource for gene prioritization in multiple species |
| Q38684171 | Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations. |
| Q92339091 | Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma |
| Q34674594 | Evaluating Adults With Idiopathic Pancreatitis for Genetic Predisposition: Higher Prevalence of Abnormal Results With Use of Complete Gene Sequencing |
| Q34658718 | Familial pancreatic cancer: genetic advances |
| Q26801332 | Framework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitis |
| Q55311728 | Frequency of CFTR, SPINK1, and cathepsin B gene mutation in North Indian population: connections between genetics and clinical data. |
| Q57091632 | Genetic Alterations of Periampullary and Pancreatic Ductal Adenocarcinoma: An Overview |
| Q37534966 | Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis |
| Q36324719 | Genetic Background and Clinical Characters of Pediatric Chronic Pancreatitis: Data and Implications from the East |
| Q48247460 | Genetic Polymorphisms: A Novel Perspective on Acute Pancreatitis. |
| Q33843764 | Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway |
| Q34292747 | Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis |
| Q34667122 | Genetic and phenotypic heterogeneity in tropical calcific pancreatitis |
| Q37208470 | Genetic aspects of tropical calcific pancreatitis |
| Q37842752 | Genetic basis of chronic pancreatitis in Asia Pacific region |
| Q37367370 | Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis |
| Q36933359 | Genetic risk factors for pancreatic disorders |
| Q35162016 | Genetic risk for alcoholic chronic pancreatitis |
| Q39398523 | Genetic risk in chronic pancreatitis: the misfolding-dependent pathway |
| Q34508844 | Genetics of acute and chronic pancreatitis: An update |
| Q27000406 | Genetics of pancreatitis |
| Q38064709 | Genetics of pancreatitis with a focus on the pancreatic ducts. |
| Q37869759 | Genetics of pancreatitis: a guide for clinicians |
| Q37156909 | Genetics of pancreatitis: a guide for clinicians |
| Q40103441 | Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis |
| Q39379745 | Genotype-phenotype correlation in 9 patients with tropical pancreatitis and identified gene mutations |
| Q36256114 | Hereditary Pancreatitis Associated With the N29T Mutation of the PRSS1 Gene in a Brazilian Family: A Case-Control Study |
| Q48074890 | Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation |
| Q24650338 | Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism |
| Q37256871 | Hereditary pancreatitis of 3 Chinese children: Case report and literature review |
| Q26739600 | Hereditary pancreatitis: current perspectives |
| Q33880616 | High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4' acidic residues |
| Q35058457 | Homozygous STIL mutation causes holoprosencephaly and microcephaly in two siblings |
| Q38757404 | Identification of a functional enhancer variant within the chronic pancreatitis-associated SPINK1 c.101A>G (p.Asn34Ser)-containing haplotype |
| Q36016998 | Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C |
| Q37638790 | Insights into the genetic risk factors for the development of pancreatic disease |
| Q36179367 | Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis |
| Q27676497 | Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation |
| Q35593014 | Loss of Bace1 in mice does not alter the severity of caerulein induced pancreatitis |
| Q97548636 | Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice |
| Q35837145 | Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis. |
| Q37362100 | Molecular basis for pancreatitis |
| Q35049102 | Mutational analysis of ATP8B1 in patients with chronic pancreatitis |
| Q52579674 | Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. |
| Q50238364 | Nationwide survey of hereditary pancreatitis in Japan |
| Q37869762 | New advances in cell physiology and pathophysiology of the exocrine pancreas |
| Q37737642 | No Association Between CEL-HYB Hybrid Allele and Chronic Pancreatitis in Asian Populations |
| Q48153726 | No significant enrichment of rare functionally defective CPA1 variants in a large Chinese idiopathic chronic pancreatitis cohort |
| Q34137364 | PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis |
| Q37231509 | PRSS1, SPINK1, CFTR, and CTRC Pathogenic Variants in Korean Patients With Idiopathic Pancreatitis |
| Q57651851 | Pancreas divisum |
| Q48594379 | Pancreatic Cancer Screening |
| Q37929594 | Pancreatic enzyme therapy |
| Q33764920 | Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells |
| Q36775826 | Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitis |
| Q34386673 | Pathophysiology of chronic pancreatitis |
| Q44741070 | Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study |
| Q91791071 | Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis |
| Q37802876 | Proteomic analysis of zymogen granules. |
| Q91575176 | Rapid Progression of Acute Pancreatitis to Acute Recurrent Pancreatitis in Children |
| Q57154534 | Recurrent Acute Pancreatitis: Current Concepts in the Diagnosis and Management |
| Q43161315 | Relationship of strain-dependent susceptibility to experimentally induced acute pancreatitis with regulation of Prss1 and Spink3 expression |
| Q92359714 | Risk factors for mortality in emphysematous pancreatitis |
| Q58690866 | SPINK1, PRSS1, CTRC, and CFTR Genotypes Influence Disease Onset and Clinical Outcomes in Chronic Pancreatitis |
| Q33970780 | Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis |
| Q48295919 | Severe infantile isolated exocrine pancreatic insufficiency caused by the complete functional loss of the SPINK1 gene |
| Q36423795 | Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice |
| Q30847258 | TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatitis but may interact with SPINK1 and CTSB mutations in predicting diabetes. |
| Q41708880 | Targeted next-generation sequencing effectively analyzed the cystic fibrosis transmembrane conductance regulator gene in pancreatitis |
| Q35565390 | The Common Chymotrypsinogen C (CTRC) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population. |
| Q28478610 | The absence of MIST1 leads to increased ethanol sensitivity and decreased activity of the unfolded protein response in mouse pancreatic acinar cells |
| Q41902456 | The acinar cell and early pancreatitis responses |
| Q35013336 | The c.1275A>G putative chronic pancreatitis-associated synonymous polymorphism in the glycoprotein 2 (GP2) gene decreases exon 9 inclusion |
| Q64055247 | The gene variants in Japanese children with idiopathic pancreatitis |
| Q35206902 | The genetic predisposition and its impact on the diabetes mellitus development in patients with alcoholic chronic pancreatitis |
| Q37255493 | The guinea pig pancreas secretes a single trypsinogen isoform, which is defective in autoactivation. |
| Q38257761 | The past 10 years of gastroenterology and hepatology-reflections and predictions |
| Q37686057 | The role of alcohol and smoking in pancreatitis |
| Q37065823 | Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis |
| Q64239617 | Toward a clinical diagnostic pipeline for SPINK1 intronic variants |
| Q37959209 | Update lecture: benign diseases of the exocrine pancreas |
| Q37540036 | Variants in CPA1 are strongly associated with early onset chronic pancreatitis |
| Q36174524 | Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis |
| Q30235282 | What's unique about acute pancreatitis in children: risk factors, diagnosis and management |
| Q37596314 | Zymogen activation confers thermodynamic stability on a key peptide bond and protects human cationic trypsin from degradation. |
| Q83813027 | [Chronic pancreatitis] |
| Q83629937 | [Genetically determined pancreatic diseases] |
Search more.