DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair.

scientific article

DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKG324
P932PMC publication ID153752
P698PubMed publication ID12682353
P5875ResearchGate publication ID277419079

P50authorMark C HallQ58925769
P2093author name stringThomas A Kunkel
Christoph H Borchers
Polina V Shcherbakova
Kenneth B Tomer
John M Fortune
J Michael Dial
P2860cites workInitiation of methyl-directed mismatch repairQ64389906
Passing the baton in base excision repairQ73505096
The MutL ATPase is required for mismatch repairQ73586223
Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cellsQ73626700
MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instabilityQ22010995
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repairQ27617873
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]Q27621279
Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repairQ27629464
Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPaseQ27635053
Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesisQ27766073
Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.Q27929951
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutationsQ27935158
High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimerQ27936605
Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteinsQ27937399
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correctionQ27939611
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesisQ27939891
hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNAQ28138775
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing overQ28282791
Meiotic pachytene arrest in MLH1-deficient miceQ28510650
An atypical topoisomerase II from Archaea with implications for meiotic recombinationQ29618230
Identification of in-gel digested proteins by complementary peptide mass fingerprinting and tandem mass spectrometry data obtained on an electrospray ionization quadrupole time-of-flight mass spectrometer.Q30588571
GHKL, an emergent ATPase/kinase superfamilyQ33818817
Mammalian DNA mismatch repairQ33847720
MutS mediates heteroduplex loop formation by a translocation mechanismQ33887145
Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations.Q33957827
Inactivation of DNA mismatch repair by increased expression of yeast MLH1.Q33967139
DNA mismatch repair and genetic instabilityQ34090778
DNA mismatch repair: MutS structures bound to mismatches.Q34141513
DNA mismatch repair: the hands of a genome guardian.Q34144865
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologsQ34554581
The DNA binding properties of the MutL protein isolated from Escherichia coliQ35919359
Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifsQ36159638
Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutationsQ36570003
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Methyl-directed repair of DNA base-pair mismatches in vitroQ37344016
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosisQ38293261
Escherichia coli MutL loads DNA helicase II onto DNA.Q38308417
Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosisQ38344945
Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.Q40920177
Purification of eukaryotic MutL homologs from Saccharomyces cerevisiae using self-affinity technology.Q42427963
Isolation and characterization of the Escherichia coli mutL gene product.Q54734906
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectDNA mismatch repairQ2984243
P304page(s)2025-2034
P577publication date2003-04-01
P1433published inNucleic Acids ResearchQ135122
P1476titleDNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair
P478volume31

Reverse relations

cites work (P2860)
Q37072156Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair
Q35531558DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication
Q36371989Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair
Q36764079Endonuclease activities of MutLα and its homologs in DNA mismatch repair
Q33711830Eukaryotic Mismatch Repair in Relation to DNA Replication
Q27659620Functional residues on the surface of the N-terminal domain of yeast Pms1
Q33343475Human MutLalpha: the jack of all trades in MMR is also an endonuclease
Q90429771Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex
Q28586588Mlh1 mediates tissue-specific regulation of mitotic recombination
Q34884364Modeling of the DNA-binding site of yeast Pms1 by mass spectrometry.
Q38392332Molecular classification of gastric adenocarcinoma: translating new insights from the cancer genome atlas research network
Q35537125Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair
Q34097342Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication
Q53317052PMS1 from Arabidopsis thaliana: optimization of protein overexpression in Escherichia coli.
Q36540776Roles for mismatch repair family proteins in promoting meiotic crossing over
Q35027619Single molecule studies of DNA mismatch repair
Q46919135The DNA binding activity of MutL is required for methyl-directed mismatch repair in Escherichia coli
Q28306188The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions
Q35100583The UvrD helicase and its modulation by the mismatch repair protein MutL.
Q38940735The clinicopathological significance of hMLH1 hypermethylation in non-small-cell lung cancer: a meta-analysis and literature review
Q36370907The sliding clamp tethers the endonuclease domain of MutL to DNA
Q36162012The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair
Q90622154The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair
Q30414522Use of proteinase K nonspecific digestion for selective and comprehensive identification of interpeptide cross-links: application to prion proteins
Q34193203Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice

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