H-NS: a universal regulator for a dynamic genome

scientific article published on May 2004

H-NS: a universal regulator for a dynamic genome is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1011909803
P356DOI10.1038/NRMICRO883
P698PubMed publication ID15100692
P5875ResearchGate publication ID8603443

P2093author name stringCharles J Dorman
P2860cites workEnhanced binding of altered H-NS protein to flagellar rotor protein FliG causes increased flagellar rotational speed and hypermotility in Escherichia coliQ77195516
Requirement for the molecular adapter function of StpA at the Escherichia coli bgl promoter depends upon the level of truncated H-NS proteinQ77333826
An extended role for the nucleoid structuring protein H-NS in the virulence gene regulatory cascade of Shigella flexneriQ78816863
Vibrio cholerae H‐NS domain structure and function with respect to transcriptional repression of ToxR regulon genes reveals differences among H‐NS family membersQ79293752
Identification of the Hfq-binding site on DsrA RNA: Hfq binds without altering DsrA secondary structureQ24540168
Evidence for direct protein-protein interaction between members of the enterobacterial Hha/YmoA and H-NS families of proteinsQ24544235
H-NS oligomerization domain structure reveals the mechanism for high order self-association of the intact proteinQ27640081
Structural origins of adenine-tract bendingQ27640492
The H-NS dimerization domain defines a new fold contributing to DNA recognitionQ27640522
Crystal structure of the N-terminal dimerisation domain of VicH, the H-NS-like protein of Vibrio choleraeQ27642507
Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coliQ27730385
Whole-genome random sequencing and assembly of Haemophilus influenzae RdQ27860765
Riboregulation by DsrA RNA: trans-actions for global economyQ28140236
A DNA structural atlas for Escherichia coliQ30002426
Synthetic curved DNA sequences can act as transcriptional activators in Escherichia coliQ33591850
Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria.Q33594386
Growth phase-dependent variation in protein composition of the Escherichia coli nucleoidQ33638020
Post-transcriptional control by global regulators of gene expression in bacteria.Q33879783
Clarification of the dimerization domain and its functional significance for the Escherichia coli nucleoid protein H-NSQ73940872
H-NS-Dependent regulation of flagellar synthesis is mediated by a LysR family proteinQ33994555
Shigella flexneri 2a strain 2457T expresses three members of the H-NS-like protein family: characterization of the Sfh proteinQ34219679
Lethal overproduction of the Escherichia coli nucleoid protein H-NS: ultramicroscopic and molecular autopsyQ34233352
The RNA-binding protein HF-I, known as a host factor for phage Qbeta RNA replication, is essential for rpoS translation in Escherichia coliQ34383062
Interaction of Ler at the LEE5 (tir) operon of enteropathogenic Escherichia coliQ34521490
The bacterial regulatory protein H-NS--a versatile modulator of nucleic acid structuresQ34835579
HU: promoting or counteracting DNA compaction?Q34953256
Regulation of gene expression by histone-like proteins in bacteria.Q35097677
Control of rRNA expression in Escherichia coliQ35121921
H-NS in Gram-negative bacteria: a family of multifaceted proteinsQ35579488
Effects of H-NS and potassium glutamate on sigmaS- and sigma70-directed transcription in vitro from osmotically regulated P1 and P2 promoters of proU in Escherichia coliQ35609662
Probing the structure, function, and interactions of the Escherichia coli H-NS and StpA proteins by using dominant negative derivatives.Q35610131
Differential protease-mediated turnover of H-NS and StpA revealed by a mutation altering protein stability and stationary-phase survival of Escherichia coliQ35631720
Structure of the histone-like protein H-NS and its role in regulation and genome superstructureQ35737936
Escherichia coli protein analogs StpA and H-NS: regulatory loops, similar and disparate effects on nucleic acid dynamicsQ35846232
Identification and sequence determination of the host factor gene for bacteriophage Q betaQ35916036
The H-NS protein is involved in the biogenesis of flagella in Escherichia coliQ35974947
Stress response of Escherichia coli to elevated hydrostatic pressure.Q36123732
Gene 5.5 protein of bacteriophage T7 inhibits the nucleoid protein H-NS of Escherichia coliQ36129355
Multiple effects of Fis on integration and the control of lysogeny in phage lambdaQ36148023
Rapid site-specific DNA inversion in Escherichia coli mutants lacking the histonelike protein H-NSQ36148365
Identification of a cold shock transcriptional enhancer of the Escherichia coli gene encoding nucleoid protein H-NS.Q37637931
A molecular mechanism for the repression of transcription by the H-NS proteinQ38291337
Large-scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid-associated protein, H-NS.Q38302084
The nucleoid-associated protein StpA binds curved DNA, has a greater DNA-binding affinity than H-NS and is present in significant levels in hns mutantsQ38302753
A role for the Escherichia coli H-NS-like protein StpA in OmpF porin expression through modulation of micF RNA stabilityQ38307599
Transcriptional control of the invasion regulatory gene virB of Shigella flexneri: activation by virF and repression by H-NSQ38315694
Identification of the DNA binding surface of H-NS protein from Escherichia coli by heteronuclear NMR spectroscopyQ38322291
Lac and lambda repressors relieve silencing of the Escherichia coli bgl promoter. Activation by alteration of a repressing nucleoprotein complexQ38330850
Domain structure and RNA annealing activity of the Escherichia coli regulatory protein StpA.Q38336063
The virF promoter in Shigella: more than just a curved DNA stretchQ38345190
The oligomeric structure of nucleoid protein H-NS is necessary for recognition of intrinsically curved DNA and for DNA bending.Q38347186
Role for the histone-like protein H-NS in growth phase-dependent and osmotic regulation of sigma S and many sigma S-dependent genes in Escherichia coliQ39474355
Silencing and activation of ClyA cytotoxin expression in Escherichia coliQ39501275
Heteromeric interactions among nucleoid-associated bacterial proteins: localization of StpA-stabilizing regions in H-NS of Escherichia coliQ39503249
H-NS mediated compaction of DNA visualised by atomic force microscopyQ39584438
Silencing of the Escherichia coli bgl promoter: effects of template supercoiling and cell extracts on promoter activity in vitroQ39716600
Fine-structure deletion analysis of the transcriptional silencer of the proU operon of Salmonella typhimuriumQ39837835
Serratia marcescens contains a heterodimeric HU protein like Escherichia coli and Salmonella typhimuriumQ39839820
The Escherichia coli stpA gene is transiently expressed during growth in rich medium and is induced in minimal medium and by stress conditions.Q39844343
The small nucleoid-binding proteins H-NS, HU, and Fis affect hilA expression in Salmonella enterica serovar TyphimuriumQ39863987
A role for H-NS in the thermo-osmotic regulation of virulence gene expression in Shigella flexneriQ39932607
Increased bending rigidity of single DNA molecules by H-NS, a temperature and osmolarity sensorQ40233805
Conservation of DNA curvature signals in regulatory regions of prokaryotic genesQ40315231
How is osmotic regulation of transcription of the Escherichia coli proU operon achieved? A review and a modelQ41397370
The hha gene modulates haemolysin expression in Escherichia coliQ42625501
The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneriQ42638971
Transcriptional regulation of type III secretion genes in enteropathogenic Escherichia coli: Ler antagonizes H-NS-dependent repressionQ42641819
Thermoregulation of Shigella and Escherichia coli EIEC pathogenicity. A temperature-dependent structural transition of DNA modulates accessibility of virF promoter to transcriptional repressor H-NS.Q42662171
Structural basis for H-NS-mediated trapping of RNA polymerase in the open initiation complex at the rrnB P1.Q42664136
The looped domain organization of the nucleoid in histone-like protein defective Escherichia coli strainsQ43791968
Expression of the gene encoding the major bacterial nucleoid protein H-NS is subject to transcriptional auto-repressionQ47673047
Effects of the Escherichia coli DNA-binding protein H-NS on rRNA synthesis in vivoQ47956517
Fis, a DNA nucleoid-associated protein, is involved in Salmonella typhimurium SPI-1 invasion gene expressionQ50117798
Oligomerization of the chromatin-structuring protein H-NS.Q50120784
Expression and mutational analysis of the nucleoid-associated protein H-NS of Salmonella typhimuriumQ50174655
Characterization of the negative elements involved in silencing the bgl operon of Escherichia coli: possible roles for DNA gyrase, H-NS, and CRP-cAMP in regulation.Q52194747
Synthesis of the Escherichia coli K-12 nucleoid-associated DNA-binding protein H-NS is subjected to growth-phase control and autoregulation.Q52516580
Effects of local transcription and H-NS on inversion of the fim switch of Escherichia coli.Q52921610
Conformational changes of the upstream DNA mediated by H-NS and FIS regulate E. coli RrnB P1 promoter activity.Q53937403
H-NS and Lrp serve as positive modulators of traJ expression from the Escherichia coli plasmid pRK100.Q54519524
Posttranslational modification of E. coli histone-like protein H-NS and bovine histones by short-chain poly-(R)-3-hydroxybutyrate (cPHB).Q54538487
The degree of oligomerization of the H-NS nucleoid structuring protein is related to specific binding to DNA.Q54539177
Systematic mutational analysis revealing the functional domain organization of Escherichia coli nucleoid protein H-NS.Q54578667
Regulation of HU alpha and HU beta by CRP and FIS in Escherichia coli.Q54578674
Antagonistic involvement of FIS and H-NS proteins in the transcriptional control of hns expression.Q54592494
Autoregulatory expression of the Escherichia coli hns gene encoding a nucleoid protein: H-NS functions as a repressor of its own transcription.Q54664095
Molecular analysis of the Escherichia coli has gene encoding a DNA-binding protein, which preferentially recognizes curved DNA sequencesQ54689751
An Escherichia coli protein that preferentially binds to sharply curved DNA.Q54709379
Multimeric Self-assembly Equilibria Involving the Histone-like Protein H-NS: A THERMODYNAMIC STUDYQ56838392
The genomes of Pseudomonas encode a third HU proteinQ57936081
Environmental Influences on DNA CurvatureQ58066731
H-NS-dependent activation of pectate lyases synthesis in the phytopathogenic bacteriumErwinia chrysanthemiis mediated by the PecT repressorQ60671606
Involvement of FIS in the H-NS-mediated regulation of virF gene of Shigella and enteroinvasive Escherichia coliQ61775013
Regulation of gene expression in Vibrio cholerae by ToxT involves both antirepression and RNA polymerase stimulationQ64449517
Coupling of Escherichia coli hns mRNA levels to DNA synthesis by autoregulation: implications for growth phase controlQ70989505
Role of HU proteins in forming and constraining supercoils of chromosomal DNA in Escherichia coliQ71522700
Fluorescence Analysis of the Escherichia coli Transcription Regulator H-NS Reveals Two Distinguishable Complexes Dependent on Binding to Specific or Nonspecific DNA SitesQ72054991
Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinityQ73157405
Three-way interactions among the Sfh, StpA and H-NS nucleoid-structuring proteins of Shigella flexneri 2a strain 2457TQ73481709
Expression of the hemolysin operon in Escherichia coli is modulated by a nucleoid-protein complex that includes the proteins Hha and H-NSQ73706944
Variation in HU composition during growth of Escherichia coli: the heterodimer is required for long term survivalQ73876610
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)391-400
P577publication date2004-05-01
P1433published inNature Reviews MicrobiologyQ1071797
P1476titleH-NS: a universal regulator for a dynamic genome
P478volume2

Reverse relations

cites work (P2860)
Q90619860A bacteriophage mimic of the bacterial nucleoid-associated protein Fis
Q38333433A cis-spreading nucleoprotein filament is responsible for the gene silencing activity found in the promoter relay mechanism
Q36323846A genetic switch controls the production of flagella and toxins in Clostridium difficile
Q36310357A model for chromosome organization during the cell cycle in live E. coli
Q38333799A multifactor regulatory circuit involving H-NS, VirF and an antisense RNA modulates transcription of the virulence gene icsA of Shigella flexneri.
Q37461517A mutational study of Cnu reveals attractive forces between Cnu and H-NS.
Q53471267A new target for the old regulator: H-NS suppress T6SS secretory protein EvpP, the major virulence factor in the fish pathogen Edwardsiella tarda.
Q28486715A novel nucleoid-associated protein of Mycobacterium tuberculosis is a sequence homolog of GroEL
Q39891943A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA.
Q64992212A putative curved DNA region upstream of rcsA in Escherichia coli plays a key role in transcriptional regulation by H-NS.
Q41440787A regulatory network controls expression of the in vivo-expressed HreP protease of Yersinia enterocolitica
Q42045404AatA is a novel autotransporter and virulence factor of avian pathogenic Escherichia coli
Q24541586Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli.
Q36302729Additional regulatory activities of MrkH for the transcriptional expression of the Klebsiella pneumoniae mrk genes: Antagonist of H-NS and repressor
Q36503563Alba shapes the archaeal genome using a delicate balance of bridging and stiffening the DNA.
Q50288424Altered Distribution of RNA Polymerase Lacking the Omega Subunit within the Prophages along the Escherichia coli K-12 Genome.
Q34484309Altered regulation of the OmpF porin by Fis in Escherichia coli during an evolution experiment and between B and K-12 strains
Q42068068Alternate SlyA and H-NS nucleoprotein complexes control hlyE expression in Escherichia coli K-12.
Q51601566Amino acid residues in the Ler protein critical for derepression of the LEE5 promoter in enteropathogenic E. coli.
Q41775452An Interplay among FIS, H-NS, and Guanosine Tetraphosphate Modulates Transcription of the Escherichia coli cspA Gene under Physiological Growth Conditions
Q36344558An unusual feature associated with LEE1 P1 promoters in enteropathogenic Escherichia coli (EPEC).
Q38328783Antagonistic role of H-NS and GadX in the regulation of the glutamate decarboxylase-dependent acid resistance system in Escherichia coli
Q47902988Applications of Magnetic Tweezers to Studies of NAPs
Q38309827Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome.
Q33263766Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation
Q34334679Bacterial nucleoid-associated protein uncouples transcription levels from transcription timing
Q37688895Bacterial nucleoid-associated proteins, nucleoid structure and gene expression
Q36197554Basis for the essentiality of H-NS family members in Pseudomonas aeruginosa
Q41837479Biofilms formed by gram-negative bacteria undergo increased lipid a palmitoylation, enhancing in vivo survival
Q54454859Bipolar localization of the group II intron Ll.LtrB is maintained in Escherichia coli deficient in nucleoid condensation, chromosome partitioning and DNA replication.
Q64063933CRISPR Spacers Indicate Preferential Matching of Specific Virioplankton Genes
Q37323160Cell cycle progression in Caulobacter requires a nucleoid-associated protein with high AT sequence recognition
Q33231303Characterization of hns genes from Erwinia amylovora
Q42561295Characterization of the effects of salicylidene acylhydrazide compounds on type III secretion in Escherichia coli O157:H7.
Q42650546Characterization of the opposing roles of H-NS and TraJ in transcriptional regulation of the F-plasmid tra operon
Q24634543Chromosome organization by a nucleoid-associated protein in live bacteria
Q42108715Cleavage of a model DNA replication fork by a methyl-specific endonuclease.
Q34290309Comparison of the Pathogenic Potentials of Environmental and Clinical Vibrio parahaemolyticus Strains Indicates a Role for Temperature Regulation in Virulence
Q30389375Comprehensive analysis of type 1 fimbriae regulation in fimB-null strains from the multidrug resistant Escherichia coli ST131 clone
Q39265509Compromised factor-dependent transcription termination in a nusA mutant of Escherichia coli: spectrum of termination efficiencies generated by perturbations of Rho, NusG, NusA, and H-NS family proteins
Q47126826Constraints on lateral gene transfer in promoting fimbrial usher protein diversity and function
Q40076724Control of Virulence Gene Expression by the Master Regulator, CfaD, in the Prototypical Enterotoxigenic Escherichia coli Strain, H10407.
Q44448553Control of virulence gene transcription by indirect readout in Vibrio cholerae and Salmonella enterica serovar Typhimurium.
Q35171632Controlling biofilm formation, prophage excision and cell death by rewiring global regulator H-NS of Escherichia coli
Q42007285Coordination of genomic structure and transcription by the main bacterial nucleoid-associated protein HU.
Q42957296CovR activation of the dipeptide permease promoter (PdppA) in Group A Streptococcus
Q42558859CovR alleviates transcriptional silencing by a nucleoid-associated histone-like protein in Streptococcus mutans.
Q64241132CrfC Protein, a Nucleoid Partition Factor, Localizes to Nucleoid Poles via the Activities of Specific Nucleoid-Associated Proteins
Q21131620Crossing the line: selection and evolution of virulence traits
Q52930158Cyclic-di-GMP-mediated signalling within the sigma network of Escherichia coli.
Q37389789DNA bridging and antibridging: a role for bacterial nucleoid-associated proteins in regulating the expression of laterally acquired genes
Q41844405DNA bridging: a property shared among H-NS-like proteins
Q34055951DNA looping-mediated repression by histone-like protein H-NS: specific requirement of Esigma70 as a cofactor for looping
Q41045579DNA recognition for virus assembly through multiple sequence-independent interactions with a helix-turn-helix motif.
Q36026801DNA supercoiling - a global transcriptional regulator for enterobacterial growth?
Q27313514Dielectrophoresis as a tool to characterize and differentiate isogenic mutants of Escherichia coli
Q38357348Differential binding profiles of StpA in wild-type and h-ns mutant cells: a comparative analysis of cooperative partners by chromatin immunoprecipitation-microarray analysis.
Q38503832Differential dependence of StpA on H-NS in autoregulation of stpA and in regulation of bgl.
Q33621541Differential effects and interactions of endogenous and horizontally acquired H-NS-like proteins in pathogenic Escherichia coli
Q34264500Differential epigenetic compatibility of qnr antibiotic resistance determinants with the chromosome of Escherichia coli.
Q33466737Differential regulation of horizontally acquired and core genome genes by the bacterial modulator H-NS.
Q88475321Dimerization site 2 of the bacterial DNA-binding protein H-NS is required for gene silencing and stiffened nucleoprotein filament formation
Q34982570Disarming bacterial virulence through chemical inhibition of the DNA binding domain of an AraC-like transcriptional activator protein.
Q42721560Dissecting RNA chaperone activity
Q33320338Dissecting the logical types of network control in gene expression profiles
Q40736188DsrA regulatory RNA represses both hns and rbsD mRNAs through distinct mechanisms in Escherichia coli.
Q38337459EHEC Adhesins
Q35891566Effects of nucleoid proteins on DNA repression loop formation in Escherichia coli
Q90576184Engineered global regulator H-NS improves the acid tolerance of E. coli
Q34602151Engineering biofilm formation and dispersal
Q36852367Enteropathogenic and enterohemorrhagic Escherichia coli virulence gene regulation.
Q61449803Enteropathogens: Tuning Their Gene Expression for Hassle-Free Survival
Q33830279Escherichia coli biofilms.
Q64268775Everything You Always Wanted to Know About Type 1 Fimbriae, but Were Afraid to Ask
Q35187568Evolutionary adaptation of an AraC-like regulatory protein in Citrobacter rodentium and Escherichia species
Q35746849Expression noise facilitates the evolution of gene regulation
Q39668414Expression, Functional Characterization and X-ray Analysis of HosA, A Member of MarR Family of Transcription Regulator from Uropathogenic Escherichia coli.
Q33415464Fate of the H-NS-repressed bgl operon in evolution of Escherichia coli
Q90604636Fis Contributes to Resistance of Pseudomonas aeruginosa to Ciprofloxacin by Regulating Pyocin synthesis
Q34486085Function of the Histone-Like Protein H-NS in Motility of Escherichia coli: Multiple Regulatory Roles Rather than Direct Action at the Flagellar Motor
Q36362734Functional heterogeneity of the UpaH autotransporter protein from uropathogenic Escherichia coli
Q36470516Functional interactions between Sae2 and the Mre11 complex.
Q42146391Functional replacement of the oligomerization domain of H-NS by the Hha protein of Escherichia coli
Q42168572Functions of the Hha and YdgT proteins in transcriptional silencing by the nucleoid proteins, H-NS and StpA, in Escherichia coli
Q30772031GamR, the LysR-Type Galactose Metabolism Regulator, Regulates hrp Gene Expression via Transcriptional Activation of Two Key hrp Regulators, HrpG and HrpX, in Xanthomonas oryzae pv. oryzae
Q38338657Gene clusters reflecting macrodomain structure respond to nucleoid perturbations.
Q35673712Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle
Q54329564Gene silencing by H-NS from distal DNA site.
Q33517940Gene socialization: gene order, GC content and gene silencing in Salmonella
Q33218546Genetic analysis of the requirements for SOS induction by nalidixic acid in Escherichia coli
Q38358978Genome-wide identification of H-NS-controlled, temperature-regulated genes in Escherichia coli K-12.
Q90637054Genome-wide mapping of Topoisomerase I activity sites reveal its role in chromosome segregation
Q34572484Genomic analysis of the regulatory elements and links with intrinsic DNA structural properties in the shrunken genome of Buchnera
Q55132643Genomic and functional characterisation of IncX3 plasmids encoding blaSHV-12 in Escherichia coli from human and animal origin.
Q91723623H-NS Family Members MvaT and MvaU Regulate the Pseudomonas aeruginosa Type III Secretion System
Q33571629H-NS Mutation-Mediated CRISPR-Cas Activation Inhibits Phage Release and Toxin Production of Escherichia coli Stx2 Phage Lysogen
Q38292579H-NS Nucleoid Protein Controls Virulence Features of Klebsiella pneumoniae by Regulating the Expression of Type 3 Pili and the Capsule Polysaccharide
Q36146713H-NS Regulates Gene Expression and Compacts the Nucleoid: Insights from Single-Molecule Experiments
Q42058447H-NS antagonism in Shigella flexneri by VirB, a virulence gene transcription regulator that is closely related to plasmid partition factors.
Q29346604H-NS binding and repression of the ctx promoter in Vibrio cholerae
Q40694944H-NS binding to evpB and evpC and repressing T6SS expression in fish pathogen Edwardsiella piscicida
Q33254081H-NS controls metabolism and stress tolerance in Escherichia coli O157:H7 that influence mouse passage
Q36999879H-NS family members function coordinately in an opportunistic pathogen
Q27664196H-NS forms a superhelical protein scaffold for DNA condensation
Q50078838H-NS gives invading DNA the silent treatment
Q37264621H-NS is a negative regulator of the two hemolysin/cytotoxin gene clusters in Vibrio anguillarum
Q42041830H-NS is a novel transcriptional modulator of the ribonucleotide reductase genes in Escherichia coli
Q39497729H-NS is a part of a thermally controlled mechanism for bacterial gene regulation.
Q42872563H-NS mediates the dissociation of a refractory protein-DNA complex during Tn10/IS10 transposition.
Q28490022H-NS mediates the silencing of laterally acquired genes in bacteria
Q37274626H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF.
Q50074672H-NS, the genome sentinel
Q39030232H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.
Q42734633High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes
Q34297693High-order oligomerization is required for the function of the H-NS family member MvaT in Pseudomonas aeruginosa
Q30462610Higher order oligomerization is required for H-NS family member MvaT to form gene-silencing nucleoprotein filament
Q36936468HilD-mediated transcriptional cross-talk between SPI-1 and SPI-2.
Q38312050Homeostatic regulation of supercoiling sensitivity coordinates transcription of the bacterial genome
Q42283711Horizontal transfer of DNA methylation patterns into bacterial chromosomes
Q89511205Horizontally Acquired Homologs of Xenogeneic Silencers: Modulators of Gene Expression Encoded by Plasmids, Phages and Genomic Islands
Q35949232Human body temperature (37degrees C) increases the expression of iron, carbohydrate, and amino acid utilization genes in Escherichia coli K-12
Q42072559Identification and characterization of the functional toxboxes in the Vibrio cholerae cholera toxin promoter.
Q41908317Identification of basepairs within Tn5 termini that are critical sfor H-NS binding to the transpososome and regulation of Tn5 transposition
Q54293552Identification of high-specificity H-NS binding site in LEE5 promoter of enteropathogenic Esherichia coli (EPEC).
Q59328846Identifying the region responsible for Brucella abortus MucR higher-order oligomer formation and examining its role in gene regulation
Q33890020Integration Host Factor (IHF) binds to the promoter region of the phtD operon involved in phaseolotoxin synthesis in P. syringae pv. phaseolicola NPS3121.
Q36747405Integration host factor positively regulates virulence gene expression in Vibrio cholerae
Q38114847Integration of syntactic and semantic properties of the DNA code reveals chromosomes as thermodynamic machines converting energy into information
Q41824879Interaction between the bacterial nucleoid associated proteins Hha and H-NS involves a conformational change of Hha
Q35805938Interaction of the histone-like nucleoid structuring protein and the general stress response regulator RpoS at Vibrio cholerae promoters that regulate motility and hemagglutinin/protease expression
Q37247811Involvement of the leucine response transcription factor LeuO in regulation of the genes for sulfa drug efflux
Q38812569Isolating Escherichia coli strains for recombinant protein production
Q35912480Isolation of a non-genomic origin fluoroquinolone responsive regulatory element using a combinatorial bioengineering approach
Q64448469Klebsiella pneumoniae Type VI Secretion System Contributes to Bacterial Competition, Cell Invasion, Type-1 Fimbriae Expression, and In Vivo Colonization
Q41121354Lack of the H-NS Protein Results in Extended and Aberrantly Positioned DNA during Chromosome Replication and Segregation in Escherichia coli
Q42412154Ler and H-NS, regulators controlling expression of the long polar fimbriae of Escherichia coli O157:H7.
Q42039277Ler interdomain linker is essential for anti-silencing activity in enteropathogenic Escherichia coli
Q49941977LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium
Q38330605LeuO protein delimits the transcriptionally active and repressive domains on the bacterial chromosome
Q38921051Local and global regulation of transcription initiation in bacteria
Q33619316Locus of enterocyte effacement-encoded regulator (Ler) of pathogenic Escherichia coli competes off histone-like nucleoid-structuring protein (H-NS) through noncooperative DNA binding
Q27659569Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis
Q28487533Lsr2 of Mycobacterium represents a novel class of H-NS-like proteins
Q28487199Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein
Q33826324Many chromosomal genes modulate MarA-mediated multidrug resistance in Escherichia coli
Q35075713Modes of regulation of RpoS by H-NS
Q33535790Modified intracellular-associated phenotypes in a recombinant Salmonella Typhi expressing S. Typhimurium SPI-3 sequences
Q41911354Modulation of horizontally acquired genes by the Hha-YdgT proteins in Salmonella enterica serovar Typhimurium
Q35827098Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli
Q42957507Molecular evolution of the H-NS protein: interaction with Hha-like proteins is restricted to enterobacteriaceae
Q52597474MucR binds multiple target sites in the promoter of its own gene and is a heat-stable protein: Is MucR a H-NS-like protein?
Q36497535MvaT Family Proteins Encoded on IncP-7 Plasmid pCAR1 and the Host Chromosome Regulate the Host Transcriptome Cooperatively but Differently
Q28487483Mycobacterium tuberculosis Lsr2 is a global transcriptional regulator required for adaptation to changing oxygen levels and virulence
Q33922365Mycobacterium tuberculosis nucleoid-associated DNA-binding protein H-NS binds with high-affinity to the Holliday junction and inhibits strand exchange promoted by RecA protein
Q45383502N9L and L9N mutations toggle Hha binding and hemolysin regulation by Escherichia coli and Vibrio cholerae H-NS.
Q53792036NapM, a new nucleoid-associated protein, broadly regulates gene expression and affects mycobacterial resistance to anti-tuberculosis drugs.
Q38323021Nature and mechanism of the in vivo oligomerization of nucleoid protein H-NS.
Q34161056Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid
Q36672112New insights into transcriptional regulation by H-NS
Q34007486Novel roles of LeuO in transcription regulation of E. coli genome: antagonistic interplay with the universal silencer H-NS.
Q37402014Nucleoid-associated proteins and bacterial physiology.
Q35227911Oligomerization mechanisms of an H-NS family protein, Pmr, encoded on the plasmid pCAR1 provide a molecular basis for functions of H-NS family members
Q41975124One Gene and Two Proteins: a Leaderless mRNA Supports the Translation of a Shorter Form of the Shigella VirF Regulator.
Q37895335Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches
Q39323797Overcoming H-NS-mediated transcriptional silencing of horizontally acquired genes by the PhoP and SlyA proteins in Salmonella enterica
Q45944240PerC and GrlA independently regulate Ler expression in enteropathogenic Escherichia coli.
Q33916703Phage encoded H-NS: a potential achilles heel in the bacterial defence system
Q34119223Pmr, a histone-like protein H1 (H-NS) family protein encoded by the IncP-7 plasmid pCAR1, is a key global regulator that alters host function
Q37002813Predicting antibiotic resistance
Q41824733Predicting the effect of ions on the conformation of the H-NS dimerization domain
Q64123090Predicting the mechanism and rate of H-NS binding to AT-rich DNA
Q51060085Protein oligomers studied by solid-state NMR--the case of the full-length nucleoid-associated protein histone-like nucleoid structuring protein.
Q42575832Protein-mediated molecular bridging: a key mechanism in biopolymer organization
Q30396364Quorum sensing and a global regulator TsrA control expression of type VI secretion and virulence in Vibrio cholerae.
Q35094995RNA-seq analysis identifies new genes regulated by the histone-like nucleoid structuring protein (H-NS) affecting Vibrio cholerae virulence, stress response and chemotaxis.
Q52579540Random sequences rapidly evolve into de novo promoters.
Q38724850Rational design of an artificial genetic switch: Co-option of the H-NS-repressed proU operon by the VirB virulence master regulator
Q42023847Re-engineering cellular physiology by rewiring high-level global regulatory genes.
Q39111071Reciprocal transcriptional and posttranscriptional growth-phase-dependent expression of sfh, a gene that encodes a paralogue of the nucleoid-associated protein H-NS.
Q37348683Regulation by transcription factors in bacteria: beyond description
Q36802922Regulation of fim genes in uropathogenic Escherichia coli
Q42152879Regulation of finP transcription by DNA adenine methylation in the virulence plasmid of Salmonella enterica
Q39798440Regulation of lipid biosynthesis, sliding motility, and biofilm formation by a membrane-anchored nucleoid-associated protein of Mycobacterium tuberculosis.
Q33825930Regulation of pga operon expression and biofilm formation in Actinobacillus pleuropneumoniae by sigmaE and H-NS
Q41911369Regulation of the yjjQ-bglJ operon, encoding LuxR-type transcription factors, and the divergent yjjP gene by H-NS and LeuO.
Q39098419Regulation systems of protease and hemolysin production in Vibrio vulnificus
Q42706889Regulatory control of the Escherichia coli O157:H7 lpf1 operon by H-NS and Ler.
Q36984012Regulatory elements implicated in the environmental control of invasin expression in enteropathogenic Yersinia
Q60932283Regulatory loop between the CsrA system and NhaR, a high salt/high pH regulator
Q52579807Repression by binding of H-NS within the transcription unit.
Q33911477Repression of phase-variable cup gene expression by H-NS-like proteins in Pseudomonas aeruginosa
Q34976630Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli
Q30443796Role of nucleoid-associated proteins Hha and H-NS in expression of Salmonella enterica activators HilD, HilC, and RtsA required for cell invasion
Q36958090Role of the histone-like nucleoid structuring protein in the regulation of rpoS and RpoS-dependent genes in Vibrio cholerae
Q40227942Roles for DNA supercoiling and the Fis protein in modulating expression of virulence genes during intracellular growth of Salmonella enterica serovar Typhimurium.
Q38701806Rv3852 (H-NS) of Mycobacterium tuberculosis Is Not Involved in Nucleoid Compaction and Virulence Regulation
Q36692574Salmonella: from pathogenesis to therapeutics
Q37431786Sequence-specific recognition of DNA by the C-terminal domain of nucleoid-associated protein H-NS.
Q34457585Single-molecule study on histone-like nucleoid-structuring protein (H-NS) paralogue in Pseudomonas aeruginosa: MvaU bears DNA organization mode similarities to MvaT
Q50666255SlyA and H-NS regulate transcription of the Escherichia coli K5 capsule gene cluster, and expression of slyA in Escherichia coli is temperature-dependent, positively autoregulated, and independent of H-NS.
Q53861487SspA is required for acid resistance in stationary phase by downregulation of H-NS in Escherichia coli.
Q34439342SspA up-regulates gene expression of the LEE pathogenicity island by decreasing H-NS levels in enterohemorrhagic Escherichia coli
Q24811273StpA protein from Escherichia coli condenses supercoiled DNA in preference to linear DNA and protects it from digestion by DNase I and EcoKI.
Q92565084Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins
Q27670439Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins
Q27647725Structure and Function of the Escherichia coli Protein YmgB: A Protein Critical for Biofilm Formation and Acid-resistance
Q38077247Structure and dynamics of the crenarchaeal nucleoid.
Q58286649Structure and function of archaeal histones
Q53194873Structure of the H-NS-DNA nucleoprotein complex.
Q37224748Synthetic tolerance: three noncoding small RNAs, DsrA, ArcZ and RprA, acting supra-additively against acid stress
Q38056151Targeting the global regulator Lsr2 as a novel approach for anti-tuberculosis drug development
Q37402032Temperature sensors of eubacteria
Q42863256Temperature-dependent conjugative transfer of R27: role of chromosome- and plasmid-encoded Hha and H-NS proteins
Q41356876The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria.
Q28533887The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence
Q29346718The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets
Q41402756The H-NS protein silences the pyp regulatory network of Yersinia enterocolitica and is involved in controlling biofilm formation
Q37122992The Histone-Like Nucleoid Structuring Protein (H-NS) Is a Negative Regulator of the Lateral Flagellar System in the Deep-Sea Bacterium Shewanella piezotolerans WP3.
Q58066651The Importance of Virulence Prediction and Gene Networks in Microbial Risk Assessment
Q47132224The Intriguing Evolutionary Journey of Enteroinvasive E. coli (EIEC) toward Pathogenicity.
Q33699768The LEE1 promoters from both enteropathogenic and enterohemorrhagic Escherichia coli can be activated by PerC-like proteins from either organism
Q58286818The Major Architects of Chromatin: Architectural Proteins in Bacteria, Archaea and Eukaryotes
Q40736749The Master Quorum-Sensing Regulator OpaR is Activated Indirectly by H-NS in Vibrio parahaemolyticus
Q48063436The Mitochondrial DNA-Associated Protein SWIB5 Influences mtDNA Architecture and Homologous Recombination
Q55263726The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection.
Q28072947The Multifaceted Activity of the VirF Regulatory Protein in the Shigella Lifestyle
Q38298617The RovA regulons of Yersinia enterocolitica and Yersinia pestis are distinct: evidence that many RovA-regulated genes were acquired more recently than the core genome
Q50027215The Transcriptional Regulator HlyU Positively Regulates exsA Expression Leading to Type III Secretion System-1 Activation in Vibrio parahaemolyticus.
Q39969385The absence of inorganic salt is required for the crystallization of the complete oligomerization domain of Salmonella typhimurium histone-like nucleoid-structuring protein
Q35220559The cation-responsive protein NhaR of Escherichia coli activates pgaABCD transcription, required for production of the biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine
Q26782828The extended regulatory networks of SXT/R391 integrative and conjugative elements and IncA/C conjugative plasmids
Q34009176The global regulator H-NS acts directly on the transpososome to promote Tn10 transposition
Q58049666The high-pressure shock response inEscherichia coli: a short survey
Q35827107The histone-like nucleoid structuring protein (H-NS) is a repressor of Vibrio cholerae exopolysaccharide biosynthesis (vps) genes
Q34709533The leucine-responsive regulatory protein, Lrp, activates transcription of the fim operon in Salmonella enterica serovar typhimurium via the fimZ regulatory gene.
Q28492558The multifaceted proteins MvaT and MvaU, members of the H-NS family, control arginine metabolism, pyocyanin synthesis, and prophage activation in Pseudomonas aeruginosa PAO1
Q36658260The novel Hha/YmoA family of nucleoid-associated proteins: use of structural mimicry to modulate the activity of the H-NS family of proteins
Q35585047The nucleoid as a smart polymer.
Q36503444The regulator HlyU, the repeat-in-toxin gene rtxA1, and their roles in the pathogenesis of Vibrio vulnificus infections
Q34805700The regulatory utilization of genetic redundancy through responsive backup circuits
Q22065692The role of nucleoid-associated proteins in the organization and compaction of bacterial chromatin
Q38647767The spectrum of activity of the small RNA DsrA: not so narrow after all.
Q33869046The stealth episome: suppression of gene expression on the excised genomic island PPHGI-1 from Pseudomonas syringae pv. phaseolicola
Q90315218The transcriptional regulator IscR integrates host-derived nitrosative stress and iron starvation in activation of the vvhBA operon in Vibrio vulnificus
Q34254123The use of the HRM method for identifying possible mutations in the ymoA gene region and evaluating their influence on the enterotoxic properties of Y. enterocolitica strains
Q38068486Thermosensing to adjust bacterial virulence in a fluctuating environment
Q43040765Time-resolved assembly of a nucleoprotein complex between Shigella flexneri virF promoter and its transcriptional repressor H-NS.
Q36893565Tracking bacterial virulence: global modulators as indicators.
Q36701127Transcription profile of Escherichia coli: genomic SELEX search for regulatory targets of transcription factors
Q33963003Transcriptional analysis of the grlRA virulence operon from Citrobacter rodentium
Q36648422Transpososome dynamics and regulation in Tn10 transposition
Q36132539Type 3 Fimbriae Encoded on Plasmids Are Expressed from a Unique Promoter without Affecting Host Motility, Facilitating an Exceptional Phenotype That Enhances Conjugal Plasmid Transfer
Q28074332Type Three Secretion System in Attaching and Effacing Pathogens
Q36062473Vibrio parahaemolyticus cell biology and pathogenicity determinants
Q41388795YmoA negatively controls the expression of insecticidal genes in Yersinia enterocolitica

Search more.