Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli

scientific article published on 30 April 2007

Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.00143-07
P932PMC publication ID1913276
P698PubMed publication ID17470656
P5875ResearchGate publication ID6358745

P2093author name stringBruno Périchon
Patrice Courvalin
Marc Galimand
P2860cites workCoproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil.Q35647670
Molecular insights into aminoglycoside action and resistanceQ36034615
Emergence of ArmA and RmtB aminoglycoside resistance 16S rRNA methylases in Belgium.Q40251695
Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosaQ40543666
Plasmid-mediated 16S rRNA methylases conferring high-level aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae isolates from two Taiwanese hospitalsQ45108097
Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferaseQ46862305
Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamideQ46986597
Quinolone resistance from a transferable plasmid.Q54143628
A comparison of methods used for measuring the accumulation of quinolones by Enterobacteriaceae, Pseudomonas aeruginosa and Staphylococcus aureus.Q54689955
Interactions of a small RNA with antibiotic and RNA ligands of the 30S subunitQ59062684
Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics. The effect of drug concentrationQ72059483
Molecular properties of bacterial multidrug transportersQ28139376
Efflux-mediated multiresistance in Gram-negative bacteriaQ28237101
Interaction of antibiotics with functional sites in 16S ribosomal RNAQ29616813
Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548Q33883595
Structural origins of gentamicin antibiotic actionQ33889995
Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoproteinQ33978735
Novel plasmid-mediated 16S rRNA methylase, RmtC, found in a proteus mirabilis isolate demonstrating extraordinary high-level resistance against various aminoglycosides.Q34301499
AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutantsQ34370243
Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosidesQ34397023
Aminoglycoside resistance by ArmA-mediated ribosomal 16S methylation in human bacterial pathogens.Q34515461
The worldwide emergence of plasmid-mediated quinolone resistanceQ34569740
Mechanisms of quinolone action and microbial responseQ35110237
Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylationQ35165835
Plasmid-mediated 16S rRNA methylase in Serratia marcescens conferring high-level resistance to aminoglycosides.Q35548233
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)2464-2469
P577publication date2007-04-30
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleTransferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli
P478volume51

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cites work (P2860)
Q35451219Acquired antibiotic resistance genes: an overview.
Q35084648Aminoglycoside resistance 16S rRNA methyltransferases block endogenous methylation, affect translation efficiency and fitness of the host.
Q64978675An evaluation of multidrug-resistant Escherichia coli isolates in urinary tract infections from Aguascalientes, Mexico: cross-sectional study.
Q34432199Antibiotic-resistant Escherichia coli bacteria, including strains with genes encoding the extended-spectrum beta-lactamase and QnrS, in waterbirds on the Baltic Sea Coast of Poland
Q57300031Antibiotics, Resistome and Resistance Mechanisms: A Bacterial Perspective
Q37570567Characteristics of Quinolone Resistance in Escherichia coli Isolates from Humans, Animals, and the Environment in the Czech Republic
Q40925527Characterization of genetic structures of the QepA3 gene in clinical isolates of Enterobacteriaceae
Q50050219Characterization of multidrug-resistant, qnrB2-positive and extended-spectrum-beta-lactamase-producing Salmonella Concord and Salmonella Senftenberg isolates
Q37335894Ciprofloxacin treatment failure in a murine model of pyelonephritis due to an AAC(6')-Ib-cr-producing Escherichia coli strain susceptible to ciprofloxacin in vitro.
Q28246841Clinical management of infections caused by multidrug-resistant Enterobacteriaceae
Q36313202Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina
Q42355473Coprevalence of plasmid-mediated quinolone resistance determinants QepA, Qnr, and AAC(6')-Ib-cr among 16S rRNA methylase RmtB-producing Escherichia coli isolates from pigs
Q34737591Decreased susceptibility to ciprofloxacin among Shigella isolates in the United States, 2006 to 2009.
Q37256426Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp. in Spain
Q34991586Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics
Q36173968Development of a Pefloxacin Disk Diffusion Method for Detection of Fluoroquinolone-Resistant Salmonella enterica
Q37026587Differential distribution of plasmid-mediated quinolone resistance genes in clinical enterobacteria with unusual phenotypes of quinolone susceptibility from Argentina.
Q33876465Discovery of a gene conferring multiple-aminoglycoside resistance in Escherichia coli.
Q42002757Discrimination between native and Tn6010-associated oqxAB in Klebsiella spp., Raoultella spp., and other Enterobacteriaceae by using a two-step strategy
Q43333922Diversity and antibiotic resistance of Aeromonas spp. in drinking and waste water treatment plants
Q41186835Effect of the efflux pump QepA2 combined with chromosomally mediated mechanisms on quinolone resistance and bacterial fitness in Escherichia coli
Q37190695Emergence of plasmid-mediated quinolone resistance among non-Typhi Salmonella enterica isolates from humans in the United States
Q91951403Emerging coexistence of three PMQR genes on a multiple resistance plasmid with a new surrounding genetic structure of qnrS2 in E. coli in China
Q38029012Enterobacter cloacae complex: clinical impact and emerging antibiotic resistance
Q41109470Erratum: Acquired antibiotic resistance genes: an overview
Q42643928Existence of a novel qepA variant in quinolone resistant Escherichia coli from aquatic habitats of Bangladesh
Q42111161Expression of multidrug efflux pump genes acrAB-tolC, mdfA, and norE in Escherichia coli clinical isolates as a function of fluoroquinolone and multidrug resistance
Q35111248Extended-spectrum-beta-lactamases, AmpC beta-lactamases and plasmid mediated quinolone resistance in klebsiella spp. from companion animals in Italy
Q43611100Genetic Background and Expression of the New qepA4 Gene Variant Recovered in Clinical TEM-1- and CMY-2-Producing Escherichia coli
Q40263075Genetic characterization of fluoroquinolone resistant Escherichia coli from urban streams and municipal and hospital effluents.
Q36337074Global fluoroquinolone resistance epidemiology and implictions for clinical use.
Q43119262High level of quinolone resistance in Escherichia coli from healthy chicken broilers.
Q33831154High levels of multiresistance in quinolone resistant urinary tract isolates of Escherichia coli from Norway; a non clonal phenomen?
Q39164763High prevalence of plasmid-mediated quinolone resistance determinants in commensal members of the Enterobacteriaceae in Ho Chi Minh City, Vietnam
Q37072029High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals
Q39992753High prevalence of qnr and aac(6')-Ib-cr genes in both water-borne environmental bacteria and clinical isolates of Citrobacter freundii in China.
Q43215491High prevalence of the aac(6')-Ib-cr gene and its dissemination among Enterobacteriaceae isolates by CTX-M-15 plasmids in Bulgaria
Q41336639ISEcp1-mediated transposition of qnrB-like gene in Escherichia coli
Q43207261Identification of Qnr and AAC(6')-1b-cr plasmid-mediated fluoroquinolone resistance determinants in multidrug-resistant Enterobacter spp. isolated from extraintestinal infections in companion animals
Q37392904Impact of low-level resistance to fluoroquinolones due to qnrA1 and qnrS1 genes or a gyrA mutation on ciprofloxacin bactericidal activity in a murine model of Escherichia coli urinary tract infection
Q58098746In silico analysis of transferable QepA variants and related chromosomal efflux pumps
Q33314977Increased fluoroquinolone resistance with time in Escherichia coli from >17,000 patients at a large county hospital as a function of culture site, age, sex, and location
Q39164319International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin.
Q42062188Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM
Q87263282Mechanisms involved in quinolone resistance in Mycoplasma mycoides subsp. capri
Q35935319Mechanisms of antimicrobial resistance in Gram-negative bacilli.
Q36225422Mechanisms of drug resistance: quinolone resistance
Q35140054Molecular characterization and antimicrobial susceptibility testing of Escherichia coli isolates from patients with urinary tract infections in 20 Chinese hospitals
Q45907157Molecular screening of antibiotic-resistant determinants among multidrug-resistant clinical isolates of Proteus mirabilis from SouthWest Nigeria.
Q61805104Multidrug-Resistant Complex Emerging as a Global, Diversifying Threat
Q37291349Multiresistant Enterobacteriaceae: new threat of an old problem
Q38741903Mutations That Enhance the Ciprofloxacin Resistance of Escherichia coli with qnrA1.
Q36094929New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate
Q35297743Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae
Q90131047Novel quinolone resistance determinant, qepA8, in Shigella flexneri isolated in the United States, 2016
Q64109392Occurrence and characterization of quinolone resistant Escherichia coli from Norwegian turkey meat and complete sequence of an IncX1 plasmid encoding qnrS1
Q35698156Origin and evolution of antibiotic resistance: the common mechanisms of emergence and spread in water bodies
Q40788996Plasmid-Mediated Quinolone Resistance; Interactions between Human, Animal, and Environmental Ecologies
Q36538723Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan
Q41337698Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates.
Q34888920Plasmid-mediated quinolone resistance
Q36949478Plasmid-mediated quinolone resistance determinants qnrA, qnrB, and qnrS among clinical isolates of Enterobacteriaceae in a Korean hospital
Q30240591Plasmid-mediated quinolone resistance in Enterobacteriaceae: a systematic review with a focus on Mediterranean countries.
Q36932963Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France
Q24645356Plasmid-mediated quinolone resistance: a multifaceted threat
Q54205904Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes.
Q89591629Population bottlenecks strongly influence the evolutionary trajectory to fluoroquinolone resistance in Escherichia coli
Q37132323Predictable and unpredictable evolution of antibiotic resistance
Q33369591Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants
Q37011103Prevalence and characteristics of rmtB and qepA in Escherichia coli isolated from diseased animals in China
Q34151135Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment.
Q37072043Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period
Q34238560Prevalence of plasmid-mediated quinolone resistance genes among ciprofloxacin-nonsusceptible Escherichia coli and Klebsiella pneumoniae isolated from blood cultures in Korea
Q39205256Prevalence of quinolone resistance determinant qnrA6 among broad- and extended-spectrum beta-lactam-resistant Proteus mirabilis and Morganella morganii clinical isolates with sul1-type class 1 integron association in a Tunisian Hospital
Q41454301Quantitative contributions of target alteration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance
Q40137027Quinolone-resistant Escherichia coli isolated from birds of prey in Portugal are genetically distinct from those isolated from water environments and gulls in Portugal, Spain and Sweden
Q37595559Quinolones: action and resistance updated
Q34133116Quinolones: from antibiotics to autoinducers
Q41865434Rapid detection of aac(6')-Ib-cr quinolone resistance gene by pyrosequencing.
Q41975822Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates
Q34132128RmtC introduces G1405 methylation in 16S rRNA and confers high-level aminoglycoside resistance on Gram-positive microorganisms
Q39687011Sequence of conjugative plasmid pIP1206 mediating resistance to aminoglycosides by 16S rRNA methylation and to hydrophilic fluoroquinolones by efflux
Q42849874Sequence type ST405 Escherichia coli isolate producing QepA1, CTX-M-15, and RmtB from Detroit, Michigan.
Q34483705Structural and biochemical analysis of the pentapeptide repeat protein EfsQnr, a potent DNA gyrase inhibitor
Q37304655The SOS response promotes qnrB quinolone-resistance determinant expression
Q33464825The aminoglycoside resistance methyltransferase Sgm impedes RsmF methylation at an adjacent rRNA nucleotide in the ribosomal A site
Q34497409The aminoglycoside resistance methyltransferases from the ArmA/Rmt family operate late in the 30S ribosomal biogenesis pathway
Q37110496The pentapeptide repeat proteins MfpAMt and QnrB4 exhibit opposite effects on DNA gyrase catalytic reactions and on the ternary gyrase-DNA-quinolone complex
Q38906198Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance
Q55215658Wicked: The untold story of ciprofloxacin.
Q48053181qnr, aac(6')-Ib-cr and qepA genes in Escherichia coli and Klebsiella spp.: genetic environments and plasmid and chromosomal location
Q37072053qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin

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