The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses

scientific article published on September 2016

The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/1468-0009.12210
P932PMC publication ID5020151
P698PubMed publication ID27620683

P50authorJohn IoannidisQ6251482
P2860cites workTrust but Verify: Trial Registration and Determining Fidelity to the ProtocolQ46134381
Lessons learned from a prospective meta-analysisQ47645129
The automation of systematic reviewsQ51278060
Statistical methods for assessing the influence of study characteristics on treatment effects in 'meta-epidemiological' researchQ52036957
Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approachQ52920486
Ranking antidepressantsQ53056709
Seeding trials: just say "no".Q53133726
Trusting researchers to use open trial registers such as PROSPERO responsibly.Q55057430
How many Cochrane reviews are needed to cover existing evidence on the effects of health care interventions?Q73613994
Antidepressants and suicide. The history of a controversy--and where it stands todayQ80700808
An evidence-based medicine methodology to bridge the gap between clinical and environmental health sciencesQ84069114
Beyond conflict of interest. Non-financial conflicts of interest are more serious than financial conflictsQ95796326
Why most published research findings are falseQ21092395
Epidemiology and reporting characteristics of systematic reviewsQ21144675
The need for randomization in animal trials: an overview of systematic reviewsQ21559463
Drug discovery in jeopardyQ22306297
Drug development: Raise standards for preclinical cancer researchQ22348097
Selective Publication of Antidepressant Trials and Its Influence on Apparent EfficacyQ23791313
The COMET (Core Outcome Measures in Effectiveness Trials) Initiative: Its Role in Improving Cochrane ReviewsQ24199056
Publication bias in reports of animal stroke studies leads to major overstatement of efficacyQ24273209
Following 411 Cochrane protocols to completion: a retrospective cohort studyQ24288733
How to make more published research trueQ24288766
Seventy-five trials and eleven systematic reviews a day: how will we ever keep up?Q24288768
Reproducible Research Practices and Transparency across the Biomedical LiteratureQ24288789
PROSPERO at one year: an evaluation of its utilityQ24288905
Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials?Q24288917
Evidence based medicine: a movement in crisis?Q24289042
Partisan perspectives in the medical literature: a study of high frequency editorialists favoring hormone replacement therapyQ24289488
Methodology and Reports of Systematic Reviews and Meta-analysesQ24289547
Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory commentsQ24568345
Biomedical research: increasing value, reducing wasteQ24707976
Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysisQ24718169
A systematic evaluation of the quality of meta-analyses in the critical care literatureQ24813491
Quality of reporting in systematic reviews of adverse events: systematic reviewQ26828986
Dissemination bias in systematic reviews of animal research: a systematic reviewQ28080709
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaborationQ28131636
Sea change in open science and data sharing: leadership by industryQ28656418
The power of meta-analysis in genome-wide association studiesQ28658972
High reprint orders in medical journals and pharmaceutical industry funding: case-control studyQ28727838
The nuts and bolts of PROSPERO: an international prospective register of systematic reviewsQ28736175
Believe it or not: how much can we rely on published data on potential drug targets?Q29547529
Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanationQ29615706
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysisQ29619093
How evidence-based medicine is failing due to biased trials and selective publication.Q30362457
How useful are systematic reviews for informing palliative care practice? Survey of 25 Cochrane systematic reviewsQ30483437
Ushering in a new era of open science through data sharing: the wall must come downQ30486017
Systematic reviews and meta-analyses on treatment of asthma: critical evaluationQ30841561
Reanalyses of randomized clinical trial dataQ30849007
Industry-supported meta-analyses compared with meta-analyses with non-profit or no support: differences in methodological quality and conclusionsQ33368267
Promotional Tone in Reviews of Menopausal Hormone Therapy After the Women's Health Initiative: An Analysis of Published ArticlesQ33851285
Reviewing the reviews. How strong is the evidence? How clear are the conclusions?Q33956588
Comparative benefits and harms of second-generation antidepressants for treating major depressive disorder: an updated meta-analysisQ34029684
Multisystem failure: the story of anti-influenza drugsQ34040533
Meta-analyses in orthopaedic surgery. A systematic review of their methodologies.Q34155600
The False-positive to False-negative Ratio in Epidemiologic StudiesQ34178142
The medical review article: state of the scienceQ34191468
Cochrane and non-Cochrane systematic reviews in leading orthodontic journals: a quality paradigm?Q34268786
The Cochrane Collaboration.Q34340498
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescenceQ34494429
Meta-analyses with industry involvement are massively published and report no caveats for antidepressantsQ34495405
A comparison of the quality of Cochrane reviews and systematic reviews published in paper-based journalsQ34545769
Discussion sections in reports of controlled trials published in general medical journalsQ34661945
The Geometric Increase in Meta-Analyses from China in the Genomic EraQ34775813
Evaluation of excess significance bias in animal studies of neurological diseasesQ34844822
The methodology for developing a prospective meta-analysis in the family planning communityQ35011344
Cochrane reviews compared with industry supported meta-analyses and other meta-analyses of the same drugs: systematic reviewQ35082900
The proposed rule for U.S. clinical trial registration and results submissionQ35130427
Systematic reviews of animal studies; missing link in translational research?Q35132083
Evaluating the quality of evidence from a network meta-analysis.Q35200686
Survey of systematic reviews in dentistryQ35764811
A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarctionQ35879688
Epidemiology and Reporting Characteristics of Systematic Reviews of Biomedical Research: A Cross-Sectional StudyQ36027782
Evaluating meta-analyses in the general surgical literature: a critical appraisalQ36053431
Relative citation impact of various study designs in the health sciencesQ36130841
Financial ties and concordance between results and conclusions in meta-analyses: retrospective cohort studyQ36248519
Increasing value and reducing waste in research design, conduct, and analysisQ36420861
Why have meta-analyses of randomized controlled trials of the association between non-white-blood-cell-reduced allogeneic blood transfusion and postoperative infection produced discordant results?Q36936374
Interpreting discordant indirect and multiple treatment comparison meta-analyses: an evaluation of direct acting antivirals for chronic hepatitis C infectionQ36984876
Overlapping meta-analyses on the same topic: survey of published studiesQ37027187
Primer: strengths and weaknesses of meta-analysis.Q37070233
Instruments for assessing risk of bias and other methodological criteria of published animal studies: a systematic review.Q37149764
Systematic analysis of hydroxyethyl starch (HES) reviews: proliferation of low-quality reviews overwhelms the results of well-performed meta-analysesQ37199531
Evaluation of meta-analyses in the otolaryngological literatureQ37227360
An international survey indicated that unpublished systematic reviews existQ37375356
Field-wide meta-analyses of observational associations can map selective availability of risk factors and the impact of model specificationsQ37412229
AHRQ series paper 5: grading the strength of a body of evidence when comparing medical interventions--agency for healthcare research and quality and the effective health-care programQ37549075
Publication of trials funded by the National Heart, Lung, and Blood InstituteQ37592322
Twenty years of meta-analyses in orthopaedic surgery: has quality kept up with quantity?Q37667349
Content area experts as authors: helpful or harmful for systematic reviews and meta-analyses?Q38057181
Most meta-analyses of drug interventions have narrow scopes and many focus on specific agentsQ38079314
Ensuring the integrity of clinical practice guidelines: a tool for protecting patientsQ38138934
Financial conflicts of interest and conclusions about neuraminidase inhibitors for influenza: an analysis of systematic reviewsQ38256986
Completeness of main outcomes across randomized trials in entire discipline: survey of chronic lung disease outcomes in preterm infantsQ38333214
Development of a combined database for meta-epidemiological researchQ38372326
The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanationsQ38510678
The COMET initiative database: progress and activities update (2014).Q38943784
Meta-analyses to evaluate analgesic interventions: a systematic qualitative review of their methodologyQ39467950
The Cochrane collaboration: preparing, maintaining, and disseminating systematic reviews of the effects of health careQ40756644
Meta-research: The art of getting it wrongQ40849885
Meta-analysis: current issues in research synthesisQ40936213
Stress ulcer prophylaxis in critically ill patients. Resolving discordant meta-analysesQ40936486
Cumulative meta-analysis of therapeutic trials for myocardial infarctionQ41112231
A guide to interpreting discordant systematic reviewsQ41481576
Why data sharing should be the expected normQ42605031
Why we can't trust clinical guidelinesQ43835785
The case for duplication of meta-analyses and systematic reviewsQ44063501
Bibliometrics: Is your most cited work your best?Q45954443
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmeta-analysisQ815382
systematic reviewQ1504425
P304page(s)485-514
P577publication date2016-09-01
P1433published inMilbank QuarterlyQ6850820
P1476titleThe Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses
P478volume94

Reverse relations

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